Wasf3 (WASP family member 3) - Rat Genome Database

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Gene: Wasf3 (WASP family member 3) Heterocephalus glaber
Analyze
Symbol: Wasf3
Name: WASP family member 3
RGD ID: 18931715
Description: ENCODES a protein that exhibits actin binding (inferred); Arp2/3 complex binding (inferred); protein kinase A regulatory subunit binding (inferred); INVOLVED IN lamellipodium assembly (ortholog); oligodendrocyte development (ortholog); positive regulation of myelination (ortholog); ASSOCIATED WITH juvenile rheumatoid arthritis (ortholog); Prostatic Neoplasms (ortholog); FOUND IN glutamatergic synapse (ortholog); postsynapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: WAS protein family member 3; wiskott-Aldrich syndrome protein family member 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477611,864,652 - 11,904,295 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477611,863,880 - 11,985,087 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Wasf3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477611,864,652 - 11,904,295 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477611,863,880 - 11,985,087 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
WASF3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381326,539,139 - 26,688,948 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1326,557,683 - 26,688,948 (+)EnsemblGRCh38hg38GRCh38
GRCh371327,131,820 - 27,263,085 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361326,029,840 - 26,161,082 (+)NCBINCBI36Build 36hg18NCBI36
Build 341326,029,886 - 26,161,063NCBI
Celera138,256,077 - 8,332,052 (+)NCBICelera
Cytogenetic Map13q12.13NCBI
HuRef137,955,351 - 8,086,464 (+)NCBIHuRef
CHM1_11327,099,816 - 27,231,081 (+)NCBICHM1_1
T2T-CHM13v2.01325,753,035 - 25,902,898 (+)NCBIT2T-CHM13v2.0
Wasf3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395146,317,411 - 146,410,425 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5146,321,795 - 146,410,425 (+)EnsemblGRCm39 Ensembl
GRCm385146,385,006 - 146,473,615 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5146,384,985 - 146,473,615 (+)EnsemblGRCm38mm10GRCm38
MGSCv375147,196,582 - 147,282,701 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365146,689,240 - 146,774,650 (+)NCBIMGSCv36mm8
Celera5144,372,570 - 144,458,483 (+)NCBICelera
Cytogenetic Map5G3NCBI
cM Map585.23NCBI
Wasf3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81213,675,642 - 13,774,648 (-)NCBIGRCr8
mRatBN7.2128,563,805 - 8,660,799 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl128,562,062 - 8,660,751 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01210,297,896 - 10,391,014 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1210,298,555 - 10,391,270 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01212,401,989 - 12,493,810 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1210,379,274 - 10,474,931 (-)NCBICelera
Cytogenetic Map12p11NCBI
Wasf3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554976,102,909 - 6,190,770 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554976,100,633 - 6,190,639 (+)NCBIChiLan1.0ChiLan1.0
WASF3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21426,156,139 - 26,287,412 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11317,264,980 - 17,396,221 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0137,849,687 - 7,980,979 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11326,250,171 - 26,328,553 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1326,250,171 - 26,328,553 (+)Ensemblpanpan1.1panPan2
WASF3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12512,804,485 - 12,881,988 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2512,805,431 - 12,877,770 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2512,875,143 - 13,008,318 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02512,944,371 - 13,077,673 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2512,944,371 - 13,077,678 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12512,830,485 - 12,963,635 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02512,822,254 - 12,955,911 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02512,873,760 - 13,006,959 (-)NCBIUU_Cfam_GSD_1.0
Wasf3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945115,180,691 - 115,300,651 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936948345,899 - 465,930 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936948345,942 - 465,323 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WASF3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl114,261,177 - 4,366,253 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1114,261,121 - 4,366,258 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2113,736,220 - 3,791,727 (+)NCBISscrofa10.2Sscrofa10.2susScr3
WASF3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.135,805,115 - 5,934,764 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl35,889,263 - 5,931,662 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605738,489,195 - 38,621,738 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000008931   ⟹   ENSHGLP00000008836
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462477611,864,652 - 11,904,295 (-)Ensembl
RefSeq Acc Id: XM_004854817   ⟹   XP_004854874
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477611,863,880 - 11,985,087 (-)NCBI
RefSeq Acc Id: XM_004854818   ⟹   XP_004854875
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477611,863,880 - 11,985,087 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004854874 (Get FASTA)   NCBI Sequence Viewer  
  XP_004854875 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000008836
  ENSHGLP00100005525
GenBank Protein JAO01260 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004854875   ⟸   XM_004854818
- Peptide Label: isoform X2
RefSeq Acc Id: XP_004854874   ⟸   XM_004854817
- Peptide Label: isoform X1
- UniProtKB: A0A0P6JAG5 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000008836   ⟸   ENSHGLT00000008931


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000006350 Ensembl, ENTREZGENE
  ENSHGLG00100004186 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000008931 ENTREZGENE
  ENSHGLT00100005607 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.340 UniProtKB/TrEMBL
  6.10.280.150 UniProtKB/TrEMBL
InterPro SCAR/WAVE_fam UniProtKB/TrEMBL
  WH2_dom UniProtKB/TrEMBL
KEGG Report hgl:101719051 UniProtKB/TrEMBL
NCBI Gene Wasf3 ENTREZGENE
PANTHER PTHR12902 UniProtKB/TrEMBL
  WISKOTT-ALDRICH SYNDROME PROTEIN FAMILY MEMBER UniProtKB/TrEMBL
Pfam WH2 UniProtKB/TrEMBL
PROSITE WH2 UniProtKB/TrEMBL
SMART WH2 UniProtKB/TrEMBL
UniProt A0A0P6JAG5 ENTREZGENE, UniProtKB/TrEMBL