WASF3 (WASP family member 3) - Rat Genome Database

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Gene: WASF3 (WASP family member 3) Homo sapiens
Analyze
Symbol: WASF3
Name: WASP family member 3
RGD ID: 1346468
HGNC Page HGNC:12734
Description: Predicted to enable Arp2/3 complex binding activity and protein kinase A regulatory subunit binding activity. Involved in cytoskeleton organization and regulation of cell shape. Located in extracellular exosome.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: actin-binding protein WASF3; Brush-1; KIAA0900; protein WAVE-3; SCAR3; verprolin homology domain-containing protein 3; WAS protein family member 3; WAS protein family, member 3; WASP family protein member 3; WASP family Verprolin-homologous protein 3; WAVE3; wiskott-Aldrich syndrome protein family member 3
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: WASF5P  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381326,539,139 - 26,688,948 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1326,557,683 - 26,688,948 (+)EnsemblGRCh38hg38GRCh38
GRCh371327,131,820 - 27,263,085 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361326,029,840 - 26,161,082 (+)NCBINCBI36Build 36hg18NCBI36
Build 341326,029,886 - 26,161,063NCBI
Celera138,256,077 - 8,332,052 (+)NCBICelera
Cytogenetic Map13q12.13NCBI
HuRef137,955,351 - 8,086,464 (+)NCBIHuRef
CHM1_11327,099,816 - 27,231,081 (+)NCBICHM1_1
T2T-CHM13v2.01325,753,035 - 25,902,898 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8137235   PMID:8889548   PMID:9732292   PMID:10048485   PMID:10381382   PMID:11073096   PMID:11146629   PMID:11246027   PMID:12168954   PMID:12185600   PMID:12477932   PMID:12856283  
PMID:15057823   PMID:15280206   PMID:15670045   PMID:15752430   PMID:15826941   PMID:15907837   PMID:17623672   PMID:19395286   PMID:19801681   PMID:21105030   PMID:21544801   PMID:21834987  
PMID:21873635   PMID:21875946   PMID:21988832   PMID:22315230   PMID:22581642   PMID:22806308   PMID:22909346   PMID:22952619   PMID:23318438   PMID:23533145   PMID:23677069   PMID:24197660  
PMID:24658140   PMID:25329315   PMID:25378074   PMID:25402006   PMID:25527710   PMID:25544563   PMID:25661390   PMID:25745180   PMID:25823022   PMID:26186194   PMID:26344197   PMID:26804171  
PMID:26971088   PMID:26977009   PMID:27187154   PMID:27432794   PMID:27609421   PMID:28233357   PMID:28476025   PMID:28514442   PMID:28611215   PMID:28794159   PMID:29507755   PMID:29845225  
PMID:31038356   PMID:31540324   PMID:31542393   PMID:31871319   PMID:32104680   PMID:32296183   PMID:32307765   PMID:32359534   PMID:32377706   PMID:33467681   PMID:33594155   PMID:33961781  
PMID:34465361   PMID:35271311   PMID:35384245   PMID:35691539   PMID:36949468  


Genomics

Comparative Map Data
WASF3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381326,539,139 - 26,688,948 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1326,557,683 - 26,688,948 (+)EnsemblGRCh38hg38GRCh38
GRCh371327,131,820 - 27,263,085 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361326,029,840 - 26,161,082 (+)NCBINCBI36Build 36hg18NCBI36
Build 341326,029,886 - 26,161,063NCBI
Celera138,256,077 - 8,332,052 (+)NCBICelera
Cytogenetic Map13q12.13NCBI
HuRef137,955,351 - 8,086,464 (+)NCBIHuRef
CHM1_11327,099,816 - 27,231,081 (+)NCBICHM1_1
T2T-CHM13v2.01325,753,035 - 25,902,898 (+)NCBIT2T-CHM13v2.0
Wasf3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395146,317,411 - 146,410,425 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5146,321,795 - 146,410,425 (+)EnsemblGRCm39 Ensembl
GRCm385146,385,006 - 146,473,615 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5146,384,985 - 146,473,615 (+)EnsemblGRCm38mm10GRCm38
MGSCv375147,196,582 - 147,282,701 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365146,689,240 - 146,774,650 (+)NCBIMGSCv36mm8
Celera5144,372,570 - 144,458,483 (+)NCBICelera
Cytogenetic Map5G3NCBI
cM Map585.23NCBI
Wasf3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81213,675,642 - 13,774,648 (-)NCBIGRCr8
mRatBN7.2128,563,805 - 8,660,799 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl128,562,062 - 8,660,751 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01210,297,896 - 10,391,014 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1210,298,555 - 10,391,270 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01212,401,989 - 12,493,810 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1210,379,274 - 10,474,931 (-)NCBICelera
Cytogenetic Map12p11NCBI
Wasf3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554976,102,909 - 6,190,770 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554976,100,633 - 6,190,639 (+)NCBIChiLan1.0ChiLan1.0
WASF3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21426,156,139 - 26,287,412 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11317,264,980 - 17,396,221 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0137,849,687 - 7,980,979 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11326,250,171 - 26,328,553 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1326,250,171 - 26,328,553 (+)Ensemblpanpan1.1panPan2
WASF3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12512,804,485 - 12,881,988 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2512,805,431 - 12,877,770 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2512,875,143 - 13,008,318 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02512,944,371 - 13,077,673 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2512,944,371 - 13,077,678 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12512,830,485 - 12,963,635 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02512,822,254 - 12,955,911 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02512,873,760 - 13,006,959 (-)NCBIUU_Cfam_GSD_1.0
Wasf3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945115,180,691 - 115,300,651 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936948345,899 - 465,930 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936948345,942 - 465,323 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WASF3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl114,261,177 - 4,366,253 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1114,261,121 - 4,366,258 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2113,736,220 - 3,791,727 (+)NCBISscrofa10.2Sscrofa10.2susScr3
WASF3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.135,805,115 - 5,934,764 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl35,889,263 - 5,931,662 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605738,489,195 - 38,621,738 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Wasf3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477611,864,652 - 11,904,295 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477611,863,880 - 11,985,087 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in WASF3
30 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 13q12.11-12.3(chr13:18958091-31090460)x3 copy number gain See cases [RCV000053729] Chr13:18958091..31090460 [GRCh38]
Chr13:19532231..31664597 [GRCh37]
Chr13:18430231..30562597 [NCBI36]
Chr13:13q12.11-12.3		 pathogenic
GRCh38/hg38 13q12.11-34(chr13:19837395-114327173)x3 copy number gain See cases [RCV000053731] Chr13:19837395..114327173 [GRCh38]
Chr13:20411535..115085141 [GRCh37]
Chr13:19309535..114110750 [NCBI36]
Chr13:13q12.11-34		 pathogenic
GRCh38/hg38 13q11-34(chr13:18565048-114327173)x3 copy number gain See cases [RCV000053719] Chr13:18565048..114327173 [GRCh38]
Chr13:19139188..115085141 [GRCh37]
Chr13:18037188..114110750 [NCBI36]
Chr13:13q11-34		 pathogenic
GRCh38/hg38 13q11-13.3(chr13:18676442-37656039)x3 copy number gain See cases [RCV000053721] Chr13:18676442..37656039 [GRCh38]
Chr13:19250582..38230176 [GRCh37]
Chr13:18148582..37128176 [NCBI36]
Chr13:13q11-13.3		 pathogenic
GRCh38/hg38 13q11-34(chr13:18850545-114327173)x3 copy number gain See cases [RCV000053723] Chr13:18850545..114327173 [GRCh38]
Chr13:19296527..115085141 [GRCh37]
Chr13:18194527..114110750 [NCBI36]
Chr13:13q11-34		 pathogenic
GRCh38/hg38 13q12.11-34(chr13:18946182-114304628)x3 copy number gain See cases [RCV000053726] Chr13:18946182..114304628 [GRCh38]
Chr13:19520322..115070103 [GRCh37]
Chr13:18418322..114088205 [NCBI36]
Chr13:13q12.11-34		 pathogenic
NM_006646.5(WASF3):c.-108-19650G>T single nucleotide variant Lung cancer [RCV000097806] Chr13:26593311 [GRCh38]
Chr13:27167448 [GRCh37]
Chr13:13q12.13		 uncertain significance
GRCh38/hg38 13q12.11-34(chr13:19833130-114298614)x3 copy number gain See cases [RCV000134104] Chr13:19833130..114298614 [GRCh38]
Chr13:20407270..115064089 [GRCh37]
Chr13:19305270..114082191 [NCBI36]
Chr13:13q12.11-34		 pathogenic
GRCh38/hg38 13q11-34(chr13:18445862-114327173)x1 copy number loss See cases [RCV000135610] Chr13:18445862..114327173 [GRCh38]
Chr13:19020001..115085141 [GRCh37]
Chr13:10098739..114110750 [NCBI36]
Chr13:13q11-34		 pathogenic
GRCh38/hg38 13q12.11-14.11(chr13:19671934-40914767)x3 copy number gain See cases [RCV000137892] Chr13:19671934..40914767 [GRCh38]
Chr13:20246074..41488903 [GRCh37]
Chr13:19144074..40386903 [NCBI36]
Chr13:13q12.11-14.11		 pathogenic
GRCh38/hg38 13q12.11-34(chr13:19833130-114327106)x3 copy number gain See cases [RCV000139078] Chr13:19833130..114327106 [GRCh38]
Chr13:20407270..115085141 [GRCh37]
Chr13:19305270..114110683 [NCBI36]
Chr13:13q12.11-34		 pathogenic
GRCh38/hg38 13q11-34(chr13:18456040-114340285)x3 copy number gain See cases [RCV000140004] Chr13:18456040..114340285 [GRCh38]
Chr13:19030180..115105760 [GRCh37]
Chr13:17928180..114123862 [NCBI36]
Chr13:13q11-34		 pathogenic
GRCh38/hg38 13q11-13.2(chr13:18862146-33577351)x3 copy number gain See cases [RCV000141867] Chr13:18862146..33577351 [GRCh38]
Chr13:19436286..34151488 [GRCh37]
Chr13:18334286..33049488 [NCBI36]
Chr13:13q11-13.2		 pathogenic
GRCh38/hg38 13q12.11-34(chr13:19671934-114340331)x3 copy number gain See cases [RCV000142924] Chr13:19671934..114340331 [GRCh38]
Chr13:20246074..115085141 [GRCh37]
Chr13:19144074..114123908 [NCBI36]
Chr13:13q12.11-34		 pathogenic
GRCh38/hg38 13q11-34(chr13:18862146-114342258)x3 copy number gain See cases [RCV000143462] Chr13:18862146..114342258 [GRCh38]
Chr13:19436286..115107733 [GRCh37]
Chr13:18334286..114125835 [NCBI36]
Chr13:13q11-34		 pathogenic
GRCh38/hg38 13q12.11-34(chr13:19837395-114327173)x3 copy number gain See cases [RCV000148126] Chr13:19837395..114327173 [GRCh38]
Chr13:20411535..115085141 [GRCh37]
Chr13:19309535..114110750 [NCBI36]
Chr13:13q12.11-34		 pathogenic
GRCh37/hg19 13q12.11-34(chr13:19571503-115092569)x3 copy number gain See cases [RCV000240150] Chr13:19571503..115092569 [GRCh37]
Chr13:13q12.11-34		 pathogenic
GRCh37/hg19 13q12.11-34(chr13:19571503-115092510) copy number gain See cases [RCV000449142] Chr13:19571503..115092510 [GRCh37]
Chr13:13q12.11-34		 pathogenic
GRCh37/hg19 13q11-34(chr13:19436286-115107733)x3 copy number gain See cases [RCV000445886] Chr13:19436286..115107733 [GRCh37]
Chr13:13q11-34		 pathogenic
GRCh37/hg19 13q11-34(chr13:19436287-115107733) copy number gain See cases [RCV000510405] Chr13:19436287..115107733 [GRCh37]
Chr13:13q11-34		 pathogenic
GRCh37/hg19 13q11-34(chr13:19436287-115107733)x3 copy number gain See cases [RCV000511880] Chr13:19436287..115107733 [GRCh37]
Chr13:13q11-34		 pathogenic
GRCh37/hg19 13q12.12-13.2(chr13:24080918-34361992)x1 copy number loss Poly (ADP-Ribose) polymerase inhibitor response [RCV000626443] Chr13:24080918..34361992 [GRCh37]
Chr13:13q12.12-13.2		 drug response
GRCh37/hg19 13q11-22.1(chr13:19436286-74045459)x3 copy number gain not provided [RCV000683572] Chr13:19436286..74045459 [GRCh37]
Chr13:13q11-22.1		 pathogenic
GRCh37/hg19 13q11-34(chr13:19058717-115103529)x3 copy number gain not provided [RCV000738115] Chr13:19058717..115103529 [GRCh37]
Chr13:13q11-34		 pathogenic
GRCh37/hg19 13q11-34(chr13:19031237-115107157)x3 copy number gain not provided [RCV000750643] Chr13:19031237..115107157 [GRCh37]
Chr13:13q11-34		 pathogenic
NM_006646.6(WASF3):c.963G>A (p.Pro321=) single nucleotide variant not provided [RCV000966170] Chr13:26681300 [GRCh38]
Chr13:27255437 [GRCh37]
Chr13:13q12.13		 benign
NM_006646.6(WASF3):c.1503C>T (p.Ser501=) single nucleotide variant not provided [RCV000881921] Chr13:26685839 [GRCh38]
Chr13:27259976 [GRCh37]
Chr13:13q12.13		 benign
GRCh37/hg19 13q11-34(chr13:19436286-115107733)x3 copy number gain not provided [RCV000849129] Chr13:19436286..115107733 [GRCh37]
Chr13:13q11-34		 pathogenic
GRCh37/hg19 13q12.11-12.13(chr13:20069228-27474401)x3 copy number gain not provided [RCV000847640] Chr13:20069228..27474401 [GRCh37]
Chr13:13q12.11-12.13		 pathogenic
NM_006646.6(WASF3):c.1142C>G (p.Ala381Gly) single nucleotide variant not provided [RCV000887937] Chr13:26682765 [GRCh38]
Chr13:27256902 [GRCh37]
Chr13:13q12.13		 likely benign
NM_006646.6(WASF3):c.134-10T>C single nucleotide variant not provided [RCV000888081] Chr13:26665018 [GRCh38]
Chr13:27239155 [GRCh37]
Chr13:13q12.13		 benign
NM_006646.6(WASF3):c.1309A>G (p.Ile437Val) single nucleotide variant not provided [RCV000893805] Chr13:26682932 [GRCh38]
Chr13:27257069 [GRCh37]
Chr13:13q12.13		 benign
NM_006646.6(WASF3):c.912G>A (p.Pro304=) single nucleotide variant not provided [RCV000934281] Chr13:26681249 [GRCh38]
Chr13:27255386 [GRCh37]
Chr13:13q12.13		 likely benign
NM_006646.6(WASF3):c.928C>G (p.Pro310Ala) single nucleotide variant not provided [RCV000957292] Chr13:26681265 [GRCh38]
Chr13:27255402 [GRCh37]
Chr13:13q12.13		 likely benign
GRCh37/hg19 13p13-q34(chr13:1-115169878) copy number gain Complete trisomy 13 syndrome [RCV002280659] Chr13:1..115169878 [GRCh37]
Chr13:13p13-q34		 pathogenic
GRCh37/hg19 13q12.12-12.3(chr13:23775339-30534624)x3 copy number gain not provided [RCV001258538] Chr13:23775339..30534624 [GRCh37]
Chr13:13q12.12-12.3		 likely pathogenic
GRCh37/hg19 13q11-34(chr13:19053605-115108528)x3 copy number gain See cases [RCV001353184] Chr13:19053605..115108528 [GRCh37]
Chr13:13q11-34		 pathogenic
GRCh37/hg19 13p13-q34(chr13:1-115169878)x3 copy number gain See cases [RCV001780076] Chr13:1..115169878 [GRCh37]
Chr13:13p13-q34		 pathogenic
GRCh37/hg19 13q11-34(chr13:19436286-114981726) copy number gain not specified [RCV002053035] Chr13:19436286..114981726 [GRCh37]
Chr13:13q11-34		 pathogenic
GRCh37/hg19 13q11-34(chr13:19436286-115107733)x3 copy number gain not provided [RCV001834436] Chr13:19436286..115107733 [GRCh37]
Chr13:13q11-34		 pathogenic
GRCh37/hg19 13q11-34(chr13:19436286-115107733) copy number gain not specified [RCV002053036] Chr13:19436286..115107733 [GRCh37]
Chr13:13q11-34		 pathogenic
GRCh37/hg19 13q11-34(chr13:19253848-115108937)x3 copy number gain not provided [RCV002291540] Chr13:19253848..115108937 [GRCh37]
Chr13:13q11-34		 pathogenic
NM_006646.6(WASF3):c.920C>T (p.Pro307Leu) single nucleotide variant not specified [RCV004323682] Chr13:26681257 [GRCh38]
Chr13:27255394 [GRCh37]
Chr13:13q12.13		 uncertain significance
NM_006646.6(WASF3):c.116G>A (p.Arg39His) single nucleotide variant not specified [RCV004147481] Chr13:26642386 [GRCh38]
Chr13:27216523 [GRCh37]
Chr13:13q12.13		 uncertain significance
NM_006646.6(WASF3):c.752C>T (p.Pro251Leu) single nucleotide variant not specified [RCV004136318] Chr13:26681089 [GRCh38]
Chr13:27255226 [GRCh37]
Chr13:13q12.13		 uncertain significance
NM_006646.6(WASF3):c.169A>G (p.Asn57Asp) single nucleotide variant not specified [RCV004139221] Chr13:26665063 [GRCh38]
Chr13:27239200 [GRCh37]
Chr13:13q12.13		 uncertain significance
NM_006646.6(WASF3):c.826G>A (p.Gly276Arg) single nucleotide variant not specified [RCV004159982] Chr13:26681163 [GRCh38]
Chr13:27255300 [GRCh37]
Chr13:13q12.13		 uncertain significance
NM_006646.6(WASF3):c.917C>G (p.Pro306Arg) single nucleotide variant not specified [RCV004150398] Chr13:26681254 [GRCh38]
Chr13:27255391 [GRCh37]
Chr13:13q12.13		 uncertain significance
NM_006646.6(WASF3):c.496C>G (p.Leu166Val) single nucleotide variant not specified [RCV004194530] Chr13:26671945 [GRCh38]
Chr13:27246082 [GRCh37]
Chr13:13q12.13		 uncertain significance
NM_006646.6(WASF3):c.1399C>T (p.Arg467Trp) single nucleotide variant not specified [RCV004082111] Chr13:26685735 [GRCh38]
Chr13:27259872 [GRCh37]
Chr13:13q12.13		 uncertain significance
NM_006646.6(WASF3):c.106G>A (p.Ala36Thr) single nucleotide variant not specified [RCV004206347] Chr13:26642376 [GRCh38]
Chr13:27216513 [GRCh37]
Chr13:13q12.13		 uncertain significance
NM_006646.6(WASF3):c.233T>C (p.Val78Ala) single nucleotide variant not specified [RCV004152939] Chr13:26665127 [GRCh38]
Chr13:27239264 [GRCh37]
Chr13:13q12.13		 uncertain significance
NM_006646.6(WASF3):c.1037C>T (p.Pro346Leu) single nucleotide variant not specified [RCV004162267] Chr13:26682660 [GRCh38]
Chr13:27256797 [GRCh37]
Chr13:13q12.13		 uncertain significance
NM_006646.6(WASF3):c.345C>G (p.Asn115Lys) single nucleotide variant not specified [RCV004231721] Chr13:26667593 [GRCh38]
Chr13:27241730 [GRCh37]
Chr13:13q12.13		 uncertain significance
NM_006646.6(WASF3):c.139C>T (p.His47Tyr) single nucleotide variant not specified [RCV004115015] Chr13:26665033 [GRCh38]
Chr13:27239170 [GRCh37]
Chr13:13q12.13		 uncertain significance
NM_006646.6(WASF3):c.180C>A (p.Asn60Lys) single nucleotide variant not specified [RCV004111246] Chr13:26665074 [GRCh38]
Chr13:27239211 [GRCh37]
Chr13:13q12.13		 uncertain significance
NM_006646.6(WASF3):c.1193C>T (p.Pro398Leu) single nucleotide variant not specified [RCV004129788] Chr13:26682816 [GRCh38]
Chr13:27256953 [GRCh37]
Chr13:13q12.13		 uncertain significance
NM_006646.6(WASF3):c.1043C>T (p.Pro348Leu) single nucleotide variant not specified [RCV004259689] Chr13:26682666 [GRCh38]
Chr13:27256803 [GRCh37]
Chr13:13q12.13		 uncertain significance
NM_006646.6(WASF3):c.1184C>T (p.Pro395Leu) single nucleotide variant not specified [RCV004259827] Chr13:26682807 [GRCh38]
Chr13:27256944 [GRCh37]
Chr13:13q12.13		 uncertain significance
NM_006646.6(WASF3):c.1339G>A (p.Ala447Thr) single nucleotide variant not specified [RCV004310363] Chr13:26682962 [GRCh38]
Chr13:27257099 [GRCh37]
Chr13:13q12.13		 uncertain significance
NM_006646.6(WASF3):c.1261G>C (p.Gly421Arg) single nucleotide variant not specified [RCV004348466] Chr13:26682884 [GRCh38]
Chr13:27257021 [GRCh37]
Chr13:13q12.13		 uncertain significance
NM_006646.6(WASF3):c.224G>T (p.Arg75Leu) single nucleotide variant not specified [RCV004351114] Chr13:26665118 [GRCh38]
Chr13:27239255 [GRCh37]
Chr13:13q12.13		 uncertain significance
GRCh37/hg19 13q12.12-12.2(chr13:23329180-28663294)x3 copy number gain not specified [RCV003987034] Chr13:23329180..28663294 [GRCh37]
Chr13:13q12.12-12.2		 uncertain significance
GRCh37/hg19 13q11-13.3(chr13:19436287-36278224)x3 copy number gain not provided [RCV004442747] Chr13:19436287..36278224 [GRCh37]
Chr13:13q11-13.3		 uncertain significance
NM_006646.6(WASF3):c.1255A>G (p.Met419Val) single nucleotide variant not specified [RCV004477888] Chr13:26682878 [GRCh38]
Chr13:27257015 [GRCh37]
Chr13:13q12.13		 uncertain significance
NM_006646.6(WASF3):c.722A>G (p.His241Arg) single nucleotide variant not specified [RCV004477891] Chr13:26681059 [GRCh38]
Chr13:27255196 [GRCh37]
Chr13:13q12.13		 uncertain significance
NM_006646.6(WASF3):c.568C>T (p.Arg190Cys) single nucleotide variant not specified [RCV004477890] Chr13:26676576 [GRCh38]
Chr13:27250713 [GRCh37]
Chr13:13q12.13		 uncertain significance
NM_006646.6(WASF3):c.236A>G (p.Lys79Arg) single nucleotide variant not specified [RCV004477889] Chr13:26665130 [GRCh38]
Chr13:27239267 [GRCh37]
Chr13:13q12.13		 uncertain significance
NM_006646.6(WASF3):c.1225G>C (p.Gly409Arg) single nucleotide variant not specified [RCV004477887] Chr13:26682848 [GRCh38]
Chr13:27256985 [GRCh37]
Chr13:13q12.13		 uncertain significance
NM_006646.6(WASF3):c.1222C>G (p.Pro408Ala) single nucleotide variant not specified [RCV004477886] Chr13:26682845 [GRCh38]
Chr13:27256982 [GRCh37]
Chr13:13q12.13		 uncertain significance
NM_006646.6(WASF3):c.1190C>T (p.Pro397Leu) single nucleotide variant not specified [RCV004477885] Chr13:26682813 [GRCh38]
Chr13:27256950 [GRCh37]
Chr13:13q12.13		 uncertain significance
NM_006646.6(WASF3):c.109A>G (p.Ile37Val) single nucleotide variant not specified [RCV004477884] Chr13:26642379 [GRCh38]
Chr13:27216516 [GRCh37]
Chr13:13q12.13		 uncertain significance
miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
MIR200Bhsa-miR-200b-3pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCRFunctional MTI19801681
MIR200Bhsa-miR-200b-3pOncomiRDBexternal_infoNANA19801681
MIR200Bhsa-miR-200b-5pMirecordsexternal_info{changed}NA19801681
MIR200Ahsa-miR-200a-3pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI19801681
MIR200Ahsa-miR-200a-3pOncomiRDBexternal_infoNANA19801681
MIR429hsa-miR-429Mirtarbaseexternal_infoLuciferase reporter assayFunctional MTI19801681
MIR200Chsa-miR-200c-3pOncomiRDBexternal_infoNANA19801681
MIR31hsa-miR-31-5pOncomiRDBexternal_infoNANA21105030

Predicted Target Of
Summary Value
Count of predictions:3126
Count of miRNA genes:858
Interacting mature miRNAs:980
Transcripts:ENST00000335327, ENST00000361042, ENST00000496788
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
D6S1660  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37623,313,896 - 23,314,106UniSTSGRCh37
Build 36623,421,875 - 23,422,085RGDNCBI36
Celera624,546,849 - 24,547,059RGD
Cytogenetic Map6p23-p21UniSTS
HuRef623,255,704 - 23,255,914UniSTS
Marshfield Genetic Map640.14UniSTS
Marshfield Genetic Map640.14RGD
Genethon Genetic Map640.2UniSTS
TNG Radiation Hybrid Map612932.0UniSTS
deCODE Assembly Map646.48UniSTS
Stanford-G3 RH Map61177.0UniSTS
GeneMap99-GB4 RH Map695.73UniSTS
Whitehead-YAC Contig Map6 UniSTS
NCBI RH Map6289.3UniSTS
GeneMap99-G3 RH Map61309.0UniSTS
A008C17  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371327,260,358 - 27,260,459UniSTSGRCh37
Build 361326,158,358 - 26,158,459RGDNCBI36
Celera138,329,327 - 8,329,428RGD
Cytogenetic Map13q12UniSTS
HuRef138,083,739 - 8,083,840UniSTS
GeneMap99-GB4 RH Map1376.36UniSTS
NCBI RH Map13205.4UniSTS
D13S861E  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371327,261,991 - 27,262,070UniSTSGRCh37
Build 361326,159,991 - 26,160,070RGDNCBI36
Celera138,330,961 - 8,331,040RGD
Cytogenetic Map13q12UniSTS
HuRef138,085,373 - 8,085,452UniSTS
STS-Z40472  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371327,262,850 - 27,262,948UniSTSGRCh37
Build 361326,160,850 - 26,160,948RGDNCBI36
Celera138,331,820 - 8,331,918RGD
Cytogenetic Map13q12UniSTS
HuRef138,086,232 - 8,086,330UniSTS
GeneMap99-GB4 RH Map1384.01UniSTS
G20666  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371327,262,792 - 27,262,928UniSTSGRCh37
Build 361326,160,792 - 26,160,928RGDNCBI36
Celera138,331,762 - 8,331,898RGD
Cytogenetic Map13q12UniSTS
HuRef138,086,174 - 8,086,310UniSTS
A006B03  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371327,262,792 - 27,262,928UniSTSGRCh37
Build 361326,160,792 - 26,160,928RGDNCBI36
Celera138,331,762 - 8,331,898RGD
Cytogenetic Map13q12UniSTS
HuRef138,086,174 - 8,086,310UniSTS
GeneMap99-GB4 RH Map1386.61UniSTS
NCBI RH Map13201.7UniSTS
WI-22261  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371327,261,890 - 27,261,995UniSTSGRCh37
Build 361326,159,890 - 26,159,995RGDNCBI36
Celera138,330,860 - 8,330,965RGD
Cytogenetic Map13q12UniSTS
HuRef138,085,272 - 8,085,377UniSTS
GeneMap99-GB4 RH Map1385.99UniSTS
Whitehead-RH Map1348.4UniSTS
NCBI RH Map13203.0UniSTS
WASF3_3777  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371327,262,378 - 27,263,195UniSTSGRCh37
Build 361326,160,378 - 26,161,195RGDNCBI36
Celera138,331,348 - 8,332,165RGD
HuRef138,085,760 - 8,086,577UniSTS
RH46898  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13q12UniSTS
GeneMap99-GB4 RH Map13109.68UniSTS
NCBI RH Map13284.2UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 1351 1415 1169 78 124 26 2479 773 3616 111 1192 1247 55 1 1189 1466
Low 1007 867 527 522 563 415 1864 1415 110 297 244 343 119 15 1322 4 2
Below cutoff 30 697 21 19 975 19 10 5 6 4 16 13 2

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001291965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_006646 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011534889 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011534890 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024449315 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047430059 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047430060 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047430062 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047430063 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047430064 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054374044 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054374045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054374046 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054374047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054374048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054374049 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054374050 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054374051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB020707 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB026543 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF134305 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF454702 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK289845 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK294725 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL133590 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL159978 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL163538 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL353789 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC050283 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU736040 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471075 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068265 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S69790 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000335327   ⟹   ENSP00000335055
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1326,557,683 - 26,688,948 (+)Ensembl
RefSeq Acc Id: ENST00000361042   ⟹   ENSP00000354325
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1326,557,703 - 26,688,943 (+)Ensembl
RefSeq Acc Id: ENST00000496788
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1326,641,946 - 26,676,624 (+)Ensembl
RefSeq Acc Id: ENST00000671038   ⟹   ENSP00000499292
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1326,557,706 - 26,682,710 (+)Ensembl
RefSeq Acc Id: NM_001291965   ⟹   NP_001278894
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381326,557,703 - 26,688,945 (+)NCBI
CHM1_11327,099,816 - 27,231,081 (+)NCBI
T2T-CHM13v2.01325,771,615 - 25,902,895 (+)NCBI
Sequence:
RefSeq Acc Id: NM_006646   ⟹   NP_006637
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381326,557,683 - 26,688,948 (+)NCBI
GRCh371327,131,840 - 27,263,082 (+)NCBI
Build 361326,029,840 - 26,161,082 (+)NCBI Archive
HuRef137,955,351 - 8,086,464 (+)NCBI
CHM1_11327,099,816 - 27,231,081 (+)NCBI
T2T-CHM13v2.01325,771,595 - 25,902,898 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011534889   ⟹   XP_011533191
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381326,610,489 - 26,688,948 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011534890   ⟹   XP_011533192
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381326,641,933 - 26,688,948 (+)NCBI
Sequence:
RefSeq Acc Id: XM_024449315   ⟹   XP_024305083
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381326,539,139 - 26,688,948 (+)NCBI
Sequence:
RefSeq Acc Id: XM_047430059   ⟹   XP_047286015
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381326,593,613 - 26,688,948 (+)NCBI
RefSeq Acc Id: XM_047430060   ⟹   XP_047286016
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381326,557,683 - 26,688,948 (+)NCBI
RefSeq Acc Id: XM_047430062   ⟹   XP_047286018
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381326,610,490 - 26,688,948 (+)NCBI
RefSeq Acc Id: XM_047430063   ⟹   XP_047286019
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381326,593,613 - 26,688,948 (+)NCBI
RefSeq Acc Id: XM_047430064   ⟹   XP_047286020
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381326,557,683 - 26,688,948 (+)NCBI
RefSeq Acc Id: XM_054374044   ⟹   XP_054230019
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01325,824,456 - 25,902,898 (+)NCBI
RefSeq Acc Id: XM_054374045   ⟹   XP_054230020
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01325,807,583 - 25,902,898 (+)NCBI
RefSeq Acc Id: XM_054374046   ⟹   XP_054230021
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01325,855,912 - 25,902,898 (+)NCBI
RefSeq Acc Id: XM_054374047   ⟹   XP_054230022
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01325,753,035 - 25,902,898 (+)NCBI
RefSeq Acc Id: XM_054374048   ⟹   XP_054230023
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01325,771,595 - 25,902,898 (+)NCBI
RefSeq Acc Id: XM_054374049   ⟹   XP_054230024
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01325,824,457 - 25,902,898 (+)NCBI
RefSeq Acc Id: XM_054374050   ⟹   XP_054230025
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01325,807,583 - 25,902,898 (+)NCBI
RefSeq Acc Id: XM_054374051   ⟹   XP_054230026
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01325,771,595 - 25,902,898 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001278894 (Get FASTA)   NCBI Sequence Viewer  
  NP_006637 (Get FASTA)   NCBI Sequence Viewer  
  XP_011533191 (Get FASTA)   NCBI Sequence Viewer  
  XP_011533192 (Get FASTA)   NCBI Sequence Viewer  
  XP_024305083 (Get FASTA)   NCBI Sequence Viewer  
  XP_047286015 (Get FASTA)   NCBI Sequence Viewer  
  XP_047286016 (Get FASTA)   NCBI Sequence Viewer  
  XP_047286018 (Get FASTA)   NCBI Sequence Viewer  
  XP_047286019 (Get FASTA)   NCBI Sequence Viewer  
  XP_047286020 (Get FASTA)   NCBI Sequence Viewer  
  XP_054230019 (Get FASTA)   NCBI Sequence Viewer  
  XP_054230020 (Get FASTA)   NCBI Sequence Viewer  
  XP_054230021 (Get FASTA)   NCBI Sequence Viewer  
  XP_054230022 (Get FASTA)   NCBI Sequence Viewer  
  XP_054230023 (Get FASTA)   NCBI Sequence Viewer  
  XP_054230024 (Get FASTA)   NCBI Sequence Viewer  
  XP_054230025 (Get FASTA)   NCBI Sequence Viewer  
  XP_054230026 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAD33054 (Get FASTA)   NCBI Sequence Viewer  
  AAH50283 (Get FASTA)   NCBI Sequence Viewer  
  AAL51032 (Get FASTA)   NCBI Sequence Viewer  
  BAA74923 (Get FASTA)   NCBI Sequence Viewer  
  BAA81796 (Get FASTA)   NCBI Sequence Viewer  
  BAF82534 (Get FASTA)   NCBI Sequence Viewer  
  BAG57872 (Get FASTA)   NCBI Sequence Viewer  
  EAX08388 (Get FASTA)   NCBI Sequence Viewer  
  EAX08389 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000335055
  ENSP00000335055.5
  ENSP00000354325
  ENSP00000354325.4
  ENSP00000499292.1
GenBank Protein Q9UPY6 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_006637   ⟸   NM_006646
- Peptide Label: isoform 1
- UniProtKB: O94974 (UniProtKB/Swiss-Prot),   Q86VQ2 (UniProtKB/Swiss-Prot),   Q9UPY6 (UniProtKB/Swiss-Prot),   Q5T8P4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001278894   ⟸   NM_001291965
- Peptide Label: isoform 2
- UniProtKB: Q9UPY6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011533191   ⟸   XM_011534889
- Peptide Label: isoform X1
- UniProtKB: O94974 (UniProtKB/Swiss-Prot),   Q86VQ2 (UniProtKB/Swiss-Prot),   Q9UPY6 (UniProtKB/Swiss-Prot),   Q5T8P4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011533192   ⟸   XM_011534890
- Peptide Label: isoform X1
- UniProtKB: O94974 (UniProtKB/Swiss-Prot),   Q86VQ2 (UniProtKB/Swiss-Prot),   Q9UPY6 (UniProtKB/Swiss-Prot),   Q5T8P4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_024305083   ⟸   XM_024449315
- Peptide Label: isoform X1
- UniProtKB: Q9UPY6 (UniProtKB/Swiss-Prot),   O94974 (UniProtKB/Swiss-Prot),   Q86VQ2 (UniProtKB/Swiss-Prot),   Q5T8P4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000335055   ⟸   ENST00000335327
RefSeq Acc Id: ENSP00000354325   ⟸   ENST00000361042
RefSeq Acc Id: ENSP00000499292   ⟸   ENST00000671038
RefSeq Acc Id: XP_047286016   ⟸   XM_047430060
- Peptide Label: isoform X1
- UniProtKB: Q9UPY6 (UniProtKB/Swiss-Prot),   O94974 (UniProtKB/Swiss-Prot),   Q86VQ2 (UniProtKB/Swiss-Prot),   Q5T8P4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_047286020   ⟸   XM_047430064
- Peptide Label: isoform X2
RefSeq Acc Id: XP_047286015   ⟸   XM_047430059
- Peptide Label: isoform X1
- UniProtKB: Q9UPY6 (UniProtKB/Swiss-Prot),   O94974 (UniProtKB/Swiss-Prot),   Q86VQ2 (UniProtKB/Swiss-Prot),   Q5T8P4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_047286019   ⟸   XM_047430063
- Peptide Label: isoform X2
RefSeq Acc Id: XP_047286018   ⟸   XM_047430062
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054230022   ⟸   XM_054374047
- Peptide Label: isoform X1
- UniProtKB: Q86VQ2 (UniProtKB/Swiss-Prot),   Q9UPY6 (UniProtKB/Swiss-Prot),   O94974 (UniProtKB/Swiss-Prot),   Q5T8P4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054230023   ⟸   XM_054374048
- Peptide Label: isoform X1
- UniProtKB: Q86VQ2 (UniProtKB/Swiss-Prot),   Q9UPY6 (UniProtKB/Swiss-Prot),   O94974 (UniProtKB/Swiss-Prot),   Q5T8P4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054230026   ⟸   XM_054374051
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054230020   ⟸   XM_054374045
- Peptide Label: isoform X1
- UniProtKB: Q86VQ2 (UniProtKB/Swiss-Prot),   Q9UPY6 (UniProtKB/Swiss-Prot),   O94974 (UniProtKB/Swiss-Prot),   Q5T8P4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054230025   ⟸   XM_054374050
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054230019   ⟸   XM_054374044
- Peptide Label: isoform X1
- UniProtKB: Q86VQ2 (UniProtKB/Swiss-Prot),   Q9UPY6 (UniProtKB/Swiss-Prot),   O94974 (UniProtKB/Swiss-Prot),   Q5T8P4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054230024   ⟸   XM_054374049
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054230021   ⟸   XM_054374046
- Peptide Label: isoform X1
- UniProtKB: Q86VQ2 (UniProtKB/Swiss-Prot),   Q9UPY6 (UniProtKB/Swiss-Prot),   O94974 (UniProtKB/Swiss-Prot),   Q5T8P4 (UniProtKB/TrEMBL)
Protein Domains
WH2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9UPY6-F1-model_v2 AlphaFold Q9UPY6 1-502 view protein structure

Promoters
RGD ID:7226075
Promoter ID:EPDNEW_H18783
Type:initiation region
Name:WASF3_1
Description:WAS protein family member 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381326,557,715 - 26,557,775EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:12734 AgrOrtholog
COSMIC WASF3 COSMIC
Ensembl Genes ENSG00000132970 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000335327 ENTREZGENE
  ENST00000335327.6 UniProtKB/Swiss-Prot
  ENST00000361042 ENTREZGENE
  ENST00000361042.8 UniProtKB/Swiss-Prot
  ENST00000671038.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.340 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  6.10.280.150 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000132970 GTEx
HGNC ID HGNC:12734 ENTREZGENE
Human Proteome Map WASF3 Human Proteome Map
InterPro SCAR/WAVE_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WH2_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:10810 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 10810 ENTREZGENE
OMIM 605068 OMIM
PANTHER PTHR12902 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WISKOTT-ALDRICH SYNDROME PROTEIN FAMILY MEMBER 3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam WH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA37345 PharmGKB
PROSITE WH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART WH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A590UJ74_HUMAN UniProtKB/TrEMBL
  O94974 ENTREZGENE
  Q5T8P4 ENTREZGENE, UniProtKB/TrEMBL
  Q86VQ2 ENTREZGENE
  Q9UPY6 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary O94974 UniProtKB/Swiss-Prot
  Q86VQ2 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-02-19 WASF3  WASP family member 3  WASF3  WAS protein family member 3  Symbol and/or name change 5135510 APPROVED
2015-11-24 WASF3  WAS protein family member 3  WASF3  WAS protein family, member 3  Symbol and/or name change 5135510 APPROVED