Acads (acyl-CoA dehydrogenase short chain) - Rat Genome Database

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Gene: Acads (acyl-CoA dehydrogenase short chain) Heterocephalus glaber
Analyze
Symbol: Acads
Name: acyl-CoA dehydrogenase short chain
RGD ID: 18927533
Description: ENCODES a protein that exhibits acyl-CoA dehydrogenase activity (ortholog); butyryl-CoA dehydrogenase activity (ortholog); fatty-acyl-CoA binding (ortholog); INVOLVED IN butyrate catabolic process (ortholog); fatty acid beta-oxidation using acyl-CoA dehydrogenase (ortholog); response to glucocorticoid (ortholog); PARTICIPATES IN 3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway; 3-hydroxyacyl-CoA dehydrogenase deficiency pathway; 3-hydroxyisobutyric aciduria pathway; ASSOCIATED WITH alcohol use disorder (ortholog); congestive heart failure (ortholog); genetic disease (ortholog); FOUND IN centrosome (ortholog); mitochondrial matrix (ortholog); mitochondrial membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: acyl-CoA dehydrogenase, C-2 to C-3 short chain; Short-chain specific acyl-CoA dehydrogenase, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474712,955,118 - 12,966,242 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474712,954,635 - 12,966,320 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Acads
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474712,955,118 - 12,966,242 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474712,954,635 - 12,966,320 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
ACADS
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812120,725,826 - 120,740,008 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12120,725,774 - 120,740,008 (+)EnsemblGRCh38hg38GRCh38
GRCh3712121,163,629 - 121,177,811 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3612119,648,050 - 119,662,193 (+)NCBINCBI36Build 36hg18NCBI36
Build 3412119,626,385 - 119,640,530NCBI
Celera12120,797,834 - 120,812,046 (+)NCBICelera
Cytogenetic Map12q24.31NCBI
HuRef12118,172,924 - 118,187,098 (+)NCBIHuRef
CHM1_112121,132,346 - 121,146,588 (+)NCBICHM1_1
T2T-CHM13v2.012120,714,964 - 120,729,131 (+)NCBIT2T-CHM13v2.0
Acads
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395115,248,358 - 115,257,405 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5115,248,358 - 115,257,405 (-)EnsemblGRCm39 Ensembl
GRCm385115,110,299 - 115,119,346 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5115,110,299 - 115,119,346 (-)EnsemblGRCm38mm10GRCm38
MGSCv375115,560,308 - 115,569,322 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365115,371,298 - 115,380,312 (-)NCBIMGSCv36mm8
Celera5112,206,409 - 112,215,487 (-)NCBICelera
Cytogenetic Map5FNCBI
cM Map555.99NCBI
Acads
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81247,154,259 - 47,163,580 (+)NCBIGRCr8
mRatBN7.21241,493,650 - 41,502,897 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1241,493,626 - 41,502,898 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1242,661,140 - 42,670,447 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01243,274,797 - 43,284,104 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01242,335,363 - 42,344,671 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01247,254,503 - 47,263,747 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1247,254,484 - 47,263,747 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01249,049,549 - 49,059,164 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41242,765,284 - 42,774,528 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11242,628,671 - 42,637,916 (+)NCBI
Celera1243,112,383 - 43,121,613 (+)NCBICelera
Cytogenetic Map12q16NCBI
Acads
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545510,928,560 - 10,942,926 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545510,928,560 - 10,942,748 (-)NCBIChiLan1.0ChiLan1.0
ACADS
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210128,794,025 - 128,810,226 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112128,790,398 - 128,806,613 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012118,309,303 - 118,323,489 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112121,682,113 - 121,696,376 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12121,682,113 - 121,696,376 (+)Ensemblpanpan1.1panPan2
ACADS
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12616,572,936 - 16,584,760 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2616,572,947 - 16,584,194 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2616,574,053 - 16,587,252 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02616,837,490 - 16,850,715 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2616,837,499 - 16,850,713 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12616,798,031 - 16,811,155 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02616,873,738 - 16,886,985 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02616,916,088 - 16,929,300 (+)NCBIUU_Cfam_GSD_1.0
Acads
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118145,758,321 - 145,773,223 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936668254,595 - 272,118 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936668257,214 - 272,089 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ACADS
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1440,642,881 - 40,659,081 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11440,642,810 - 40,656,922 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21443,110,578 - 43,124,662 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap14q16.2-q23.2NCBI
ACADS
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111116,083,156 - 116,096,554 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11116,083,276 - 116,096,607 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037129,000,614 - 129,013,678 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000017802   ⟹   ENSHGLP00000017627
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474712,955,118 - 12,966,242 (-)Ensembl
RefSeq Acc Id: XM_013071726   ⟹   XP_012927180
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474712,954,635 - 12,966,319 (-)NCBI
RefSeq Acc Id: XM_021257347   ⟹   XP_021113006
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474712,954,635 - 12,966,320 (-)NCBI
Protein Sequences
Protein RefSeqs XP_012927180 (Get FASTA)   NCBI Sequence Viewer  
  XP_021113006 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB01534 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000017627
  ENSHGLP00100018254
GenBank Protein JAN96024 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_021113006   ⟸   XM_021257347
- Peptide Label: isoform X1
- UniProtKB: G5AWX3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012927180   ⟸   XM_013071726
- Peptide Label: isoform X2
- UniProtKB: G5AWX3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000017627   ⟸   ENSHGLT00000017802


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000012611 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSHGLG00100013456 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000017802 ENTREZGENE, UniProtKB/TrEMBL
  ENSHGLT00100018444 UniProtKB/TrEMBL
Gene3D-CATH 1.10.540.10 UniProtKB/TrEMBL
  2.40.110.10 UniProtKB/TrEMBL
  Butyryl-CoA Dehydrogenase, subunit A, domain 3 UniProtKB/TrEMBL
InterPro Acyl-CoA_DH_CS UniProtKB/TrEMBL
  Acyl-CoA_Oxase/DH_cen-dom UniProtKB/TrEMBL
  Acyl-CoA_Oxase/DH_mid-dom_sf UniProtKB/TrEMBL
  AcylCo_DH-like_C UniProtKB/TrEMBL
  AcylCo_DH/oxidase_C UniProtKB/TrEMBL
  AcylCoA_DH/ox_N UniProtKB/TrEMBL
  AcylCoA_DH/ox_N_sf UniProtKB/TrEMBL
  AcylCoA_DH/oxidase_NM_dom UniProtKB/TrEMBL
NCBI Gene Acads ENTREZGENE
PANTHER ACYL-COA DEHYDROGENASE UniProtKB/TrEMBL
  SHORT-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL UniProtKB/TrEMBL
Pfam Acyl-CoA_dh_1 UniProtKB/TrEMBL
  Acyl-CoA_dh_M UniProtKB/TrEMBL
  Acyl-CoA_dh_N UniProtKB/TrEMBL
PIRSF HsaA UniProtKB/TrEMBL
PROSITE ACYL_COA_DH_1 UniProtKB/TrEMBL
  ACYL_COA_DH_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF47203 UniProtKB/TrEMBL
  SSF56645 UniProtKB/TrEMBL
UniProt G5AWX3 ENTREZGENE, UniProtKB/TrEMBL