ACADS (acyl-CoA dehydrogenase short chain) - Rat Genome Database

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Gene: ACADS (acyl-CoA dehydrogenase short chain) Pan paniscus
Analyze
Symbol: ACADS
Name: acyl-CoA dehydrogenase short chain
RGD ID: 11923393
Description: ENCODES a protein that exhibits acyl-CoA dehydrogenase activity (ortholog); butyryl-CoA dehydrogenase activity (ortholog); fatty-acyl-CoA binding (ortholog); INVOLVED IN butyrate catabolic process (ortholog); fatty acid beta-oxidation using acyl-CoA dehydrogenase (ortholog); response to glucocorticoid (ortholog); PARTICIPATES IN 3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway; 3-hydroxyacyl-CoA dehydrogenase deficiency pathway; 3-hydroxyisobutyric aciduria pathway; ASSOCIATED WITH alcohol use disorder (ortholog); congestive heart failure (ortholog); genetic disease (ortholog); FOUND IN mitochondrial matrix (ortholog); mitochondrial membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: acyl-CoA dehydrogenase, C-2 to C-3 short chain; short-chain specific acyl-CoA dehydrogenase, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210128,794,025 - 128,810,226 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112128,790,398 - 128,806,613 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012118,309,303 - 118,323,489 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112121,682,113 - 121,696,376 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12121,682,113 - 121,696,376 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ACADS
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210128,794,025 - 128,810,226 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112128,790,398 - 128,806,613 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012118,309,303 - 118,323,489 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112121,682,113 - 121,696,376 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12121,682,113 - 121,696,376 (+)Ensemblpanpan1.1panPan2
ACADS
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812120,725,826 - 120,740,008 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12120,725,774 - 120,740,008 (+)EnsemblGRCh38hg38GRCh38
GRCh3712121,163,629 - 121,177,811 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3612119,648,050 - 119,662,193 (+)NCBINCBI36Build 36hg18NCBI36
Build 3412119,626,385 - 119,640,530NCBI
Celera12120,797,834 - 120,812,046 (+)NCBICelera
Cytogenetic Map12q24.31NCBI
HuRef12118,172,924 - 118,187,098 (+)NCBIHuRef
CHM1_112121,132,346 - 121,146,588 (+)NCBICHM1_1
T2T-CHM13v2.012120,714,964 - 120,729,131 (+)NCBIT2T-CHM13v2.0
Acads
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395115,248,358 - 115,257,405 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5115,248,358 - 115,257,405 (-)EnsemblGRCm39 Ensembl
GRCm385115,110,299 - 115,119,346 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5115,110,299 - 115,119,346 (-)EnsemblGRCm38mm10GRCm38
MGSCv375115,560,308 - 115,569,322 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365115,371,298 - 115,380,312 (-)NCBIMGSCv36mm8
Celera5112,206,409 - 112,215,487 (-)NCBICelera
Cytogenetic Map5FNCBI
cM Map555.99NCBI
Acads
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81247,154,259 - 47,163,580 (+)NCBIGRCr8
mRatBN7.21241,493,650 - 41,502,897 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1241,493,626 - 41,502,898 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1242,661,140 - 42,670,447 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01243,274,797 - 43,284,104 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01242,335,363 - 42,344,671 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01247,254,503 - 47,263,747 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1247,254,484 - 47,263,747 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01249,049,549 - 49,059,164 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41242,765,284 - 42,774,528 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11242,628,671 - 42,637,916 (+)NCBI
Celera1243,112,383 - 43,121,613 (+)NCBICelera
Cytogenetic Map12q16NCBI
Acads
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545510,928,560 - 10,942,926 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545510,928,560 - 10,942,748 (-)NCBIChiLan1.0ChiLan1.0
ACADS
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12616,572,936 - 16,584,760 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2616,572,947 - 16,584,194 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2616,574,053 - 16,587,252 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02616,837,490 - 16,850,715 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2616,837,499 - 16,850,713 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12616,798,031 - 16,811,155 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02616,873,738 - 16,886,985 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02616,916,088 - 16,929,300 (+)NCBIUU_Cfam_GSD_1.0
Acads
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118145,758,321 - 145,773,223 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936668254,595 - 272,118 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936668257,214 - 272,089 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ACADS
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1440,642,881 - 40,659,081 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11440,642,810 - 40,656,922 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21443,110,578 - 43,124,662 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap14q16.2-q23.2NCBI
ACADS
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111116,083,156 - 116,096,554 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11116,083,276 - 116,096,607 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037129,000,614 - 129,013,678 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Acads
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474712,955,118 - 12,966,242 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474712,954,635 - 12,966,320 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003832378 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSPPAT00000021347   ⟹   ENSPPAP00000004661
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl12121,682,113 - 121,696,376 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000021357   ⟹   ENSPPAP00000004663
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl12121,682,142 - 121,695,816 (+)Ensembl
RefSeq Acc Id: XM_003832378   ⟹   XP_003832426
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v210128,794,025 - 128,810,226 (+)NCBI
NHGRI_mPanPan112128,790,398 - 128,806,613 (+)NCBI
Mhudiblu_PPA_v012118,309,303 - 118,323,489 (+)NCBI
PanPan1.112121,682,113 - 121,696,376 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003832426 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000004661.1
  ENSPPAP00000004663.1
RefSeq Acc Id: XP_003832426   ⟸   XM_003832378
- UniProtKB: A0A2R8ZL74 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000004663   ⟸   ENSPPAT00000021357
RefSeq Acc Id: ENSPPAP00000004661   ⟸   ENSPPAT00000021347

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000019463 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000021347.1 UniProtKB/TrEMBL
  ENSPPAT00000021357.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.540.10 UniProtKB/TrEMBL
  2.40.110.10 UniProtKB/TrEMBL
  Butyryl-CoA Dehydrogenase, subunit A, domain 3 UniProtKB/TrEMBL
InterPro Acyl-CoA_DH_CS UniProtKB/TrEMBL
  Acyl-CoA_Oxase/DH_cen-dom UniProtKB/TrEMBL
  Acyl-CoA_Oxase/DH_mid-dom_sf UniProtKB/TrEMBL
  AcylCo_DH-like_C UniProtKB/TrEMBL
  AcylCo_DH/oxidase_C UniProtKB/TrEMBL
  AcylCoA_DH/ox_N UniProtKB/TrEMBL
  AcylCoA_DH/ox_N_sf UniProtKB/TrEMBL
  AcylCoA_DH/oxidase_NM_dom UniProtKB/TrEMBL
KEGG Report pps:100994372 UniProtKB/TrEMBL
NCBI Gene ACADS ENTREZGENE
PANTHER ACYL-COA DEHYDROGENASE UniProtKB/TrEMBL
  ISOVALERYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED UniProtKB/TrEMBL
Pfam Acyl-CoA_dh_1 UniProtKB/TrEMBL
  Acyl-CoA_dh_M UniProtKB/TrEMBL
  Acyl-CoA_dh_N UniProtKB/TrEMBL
PIRSF HsaA UniProtKB/TrEMBL
PROSITE ACYL_COA_DH_1 UniProtKB/TrEMBL
  ACYL_COA_DH_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF47203 UniProtKB/TrEMBL
  SSF56645 UniProtKB/TrEMBL
UniProt A0A2R8ZI63_PANPA UniProtKB/TrEMBL
  A0A2R8ZL74 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-10-04 ACADS  acyl-CoA dehydrogenase short chain    acyl-CoA dehydrogenase, C-2 to C-3 short chain  Symbol and/or name change 5135510 APPROVED