Klkb1 (kallikrein B1) - Rat Genome Database

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Gene: Klkb1 (kallikrein B1) Heterocephalus glaber
Analyze
Symbol: Klkb1
Name: kallikrein B1
RGD ID: 18919416
Description: ENCODES a protein that exhibits serine-type endopeptidase activity (inferred); serine-type peptidase activity (inferred); INVOLVED IN liver regeneration (ortholog); PARTICIPATES IN acenocoumarol pharmacodynamics pathway; alteplase pharmacodynamics pathway; aminocaproic acid pharmacodynamics pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); Bietti crystalline corneoretinal dystrophy (ortholog); FOUND IN extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: plasma kallikrein; plasma kallikrein preproprotein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476917,067,342 - 17,087,408 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476917,066,055 - 17,088,587 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Klkb1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476917,067,342 - 17,087,408 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476917,066,055 - 17,088,587 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
KLKB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384186,210,853 - 186,258,471 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4186,226,438 - 186,258,471 (+)EnsemblGRCh38hg38GRCh38
GRCh374187,148,661 - 187,179,625 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364187,385,666 - 187,416,619 (+)NCBINCBI36Build 36hg18NCBI36
Build 344187,523,820 - 187,554,773NCBI
Celera4184,471,184 - 184,503,982 (+)NCBICelera
Cytogenetic Map4q35.2NCBI
HuRef4182,900,717 - 182,930,974 (+)NCBIHuRef
CHM1_14187,125,087 - 187,156,065 (+)NCBICHM1_1
T2T-CHM13v2.04189,554,481 - 189,598,453 (+)NCBIT2T-CHM13v2.0
Klkb1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39845,719,725 - 45,747,872 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl845,719,726 - 45,747,896 (-)EnsemblGRCm39 Ensembl
GRCm38845,266,688 - 45,294,835 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl845,266,689 - 45,294,859 (-)EnsemblGRCm38mm10GRCm38
MGSCv37846,354,796 - 46,380,189 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36846,768,488 - 46,807,283 (-)NCBIMGSCv36mm8
Celera847,956,504 - 47,981,825 (-)NCBICelera
Cytogenetic Map8B1.1NCBI
cM Map825.17NCBI
Klkb1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81653,690,180 - 53,714,570 (+)NCBIGRCr8
mRatBN7.21646,958,634 - 46,982,054 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1646,958,707 - 46,982,053 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1652,351,649 - 52,374,892 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01655,728,965 - 55,752,309 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01650,991,039 - 51,014,284 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01650,151,127 - 50,175,407 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1650,152,008 - 50,175,458 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01649,874,943 - 49,898,364 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41650,248,935 - 50,272,279 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11650,248,906 - 50,272,347 (+)NCBI
Celera1644,949,240 - 44,972,564 (+)NCBICelera
Cytogenetic Map16q11NCBI
Klkb1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540322,833,982 - 22,856,389 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540322,835,544 - 22,856,355 (-)NCBIChiLan1.0ChiLan1.0
KLKB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23183,957,685 - 184,001,315 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14184,307,425 - 184,350,153 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04178,398,359 - 178,429,448 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14190,604,901 - 190,636,300 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4190,604,901 - 190,636,300 (+)Ensemblpanpan1.1panPan2
KLKB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11644,492,735 - 44,517,854 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1644,469,632 - 44,540,292 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1644,979,694 - 45,003,202 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01646,683,089 - 46,736,876 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1646,706,236 - 46,730,702 (-)EnsemblROS_Cfam_1.0 Ensembl
ROS_Cfam_1.0 Ensembl1646,683,106 - 46,700,880 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11644,675,226 - 44,698,533 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01645,288,025 - 45,311,430 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01645,418,960 - 45,442,647 (-)NCBIUU_Cfam_GSD_1.0
Klkb1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494334,872,449 - 34,882,567 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365543,228,735 - 3,256,710 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365543,227,395 - 3,256,710 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KLKB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1547,071,556 - 47,103,622 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11547,071,581 - 47,100,272 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21553,912,808 - 53,941,527 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KLKB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.17132,143,514 - 132,173,189 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl7132,144,420 - 132,173,187 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037112,465,874 - 112,497,290 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000022070   ⟹   ENSHGLP00000021860
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462476917,067,342 - 17,087,408 (+)Ensembl
RefSeq Acc Id: XM_004853057   ⟹   XP_004853114
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476917,066,055 - 17,088,587 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004853114 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000021860
GenBank Protein JAO00937 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004853114   ⟸   XM_004853057
- UniProtKB: A0A0P6JB42 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000021860   ⟸   ENSHGLT00000022070


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000015600 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000022070 ENTREZGENE
Gene3D-CATH 2.40.10.10 UniProtKB/TrEMBL
  Hepatocyte Growth Factor UniProtKB/TrEMBL
InterPro Apple UniProtKB/TrEMBL
  Pan_app UniProtKB/TrEMBL
  Peptidase_S1_PA UniProtKB/TrEMBL
  Peptidase_S1_PA_chymotrypsin UniProtKB/TrEMBL
  Peptidase_S1A UniProtKB/TrEMBL
  Trypsin_dom UniProtKB/TrEMBL
  TRYPSIN_HIS UniProtKB/TrEMBL
  TRYPSIN_SER UniProtKB/TrEMBL
KEGG Report hgl:101719264 UniProtKB/TrEMBL
NCBI Gene Klkb1 ENTREZGENE
PANTHER ACROSIN-RELATED UniProtKB/TrEMBL
  HYALIN UniProtKB/TrEMBL
Pfam PAN_1 UniProtKB/TrEMBL
  Trypsin UniProtKB/TrEMBL
PRINTS APPLEDOMAIN UniProtKB/TrEMBL
  CHYMOTRYPSIN UniProtKB/TrEMBL
PROSITE APPLE UniProtKB/TrEMBL
  PAN UniProtKB/TrEMBL
  PROKAR_LIPOPROTEIN UniProtKB/TrEMBL
  TRYPSIN_DOM UniProtKB/TrEMBL
  TRYPSIN_HIS UniProtKB/TrEMBL
  TRYPSIN_SER UniProtKB/TrEMBL
SMART APPLE UniProtKB/TrEMBL
  Tryp_SPc UniProtKB/TrEMBL
Superfamily-SCOP Hairpin loop containing domain-like UniProtKB/TrEMBL
  SSF50494 UniProtKB/TrEMBL
UniProt A0A0P6JB42 ENTREZGENE, UniProtKB/TrEMBL