Nop2 (NOP2 nucleolar protein) - Rat Genome Database

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Gene: Nop2 (NOP2 nucleolar protein) Heterocephalus glaber
Analyze
Symbol: Nop2
Name: NOP2 nucleolar protein
RGD ID: 18913692
Description: ENCODES a protein that exhibits methyltransferase activity (inferred); RNA binding (inferred); RNA methyltransferase activity (inferred); INVOLVED IN blastocyst formation (ortholog); ribosomal large subunit biogenesis (ortholog); rRNA processing (ortholog); ASSOCIATED WITH genetic disease (ortholog); Hyperphosphatemic Familial Tumoral Calcinosis 1 (ortholog); lymphoproliferative syndrome 2 (ortholog); FOUND IN nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase; putative ribosomal RNA methyltransferase NOP2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248603,273,944 - 3,284,150 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Nop2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248603,273,944 - 3,284,150 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
NOP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38126,556,871 - 6,568,291 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl126,556,863 - 6,568,691 (-)EnsemblGRCh38hg38GRCh38
GRCh37126,666,037 - 6,677,457 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36126,536,298 - 6,547,741 (-)NCBINCBI36Build 36hg18NCBI36
Build 34126,536,289 - 6,547,345NCBI
Celera128,282,899 - 8,294,342 (-)NCBICelera
Cytogenetic Map12p13.31NCBI
HuRef126,520,171 - 6,531,576 (-)NCBIHuRef
CHM1_1126,665,044 - 6,676,501 (-)NCBICHM1_1
T2T-CHM13v2.0126,567,230 - 6,578,651 (-)NCBIT2T-CHM13v2.0
Nop2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396125,108,829 - 125,121,716 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6125,108,872 - 125,121,716 (+)EnsemblGRCm39 Ensembl
GRCm386125,131,883 - 125,144,753 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6125,131,909 - 125,144,753 (+)EnsemblGRCm38mm10GRCm38
MGSCv376125,081,901 - 125,094,771 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366125,097,558 - 125,110,372 (+)NCBIMGSCv36mm8
Celera6126,801,863 - 126,814,607 (+)NCBICelera
Cytogenetic Map6F2NCBI
cM Map659.32NCBI
Nop2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84159,618,894 - 159,630,697 (+)NCBIGRCr8
mRatBN7.24157,932,731 - 157,944,462 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4157,932,716 - 157,944,459 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4164,161,797 - 164,173,528 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04159,944,712 - 159,956,443 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04158,580,682 - 158,592,424 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04157,646,759 - 157,658,502 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4157,647,082 - 157,658,390 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04224,663,955 - 224,675,686 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44161,252,117 - 161,264,321 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14161,497,375 - 161,509,257 (+)NCBI
Celera4146,669,575 - 146,681,484 (+)NCBICelera
Cytogenetic Map4q42NCBI
Nop2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554134,180,573 - 4,190,490 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554134,180,463 - 4,190,827 (-)NCBIChiLan1.0ChiLan1.0
NOP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21012,118,734 - 12,130,299 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11212,115,491 - 12,127,002 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0126,687,763 - 6,699,234 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1126,606,036 - 6,617,260 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl126,606,036 - 6,617,260 (-)Ensemblpanpan1.1panPan2
NOP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12738,441,259 - 38,453,946 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2738,441,690 - 38,453,824 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha278,162,718 - 8,175,429 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02738,795,791 - 38,808,510 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2738,795,860 - 38,808,510 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12738,667,821 - 38,680,527 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02738,709,346 - 38,722,054 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0277,641,408 - 7,654,127 (-)NCBIUU_Cfam_GSD_1.0
Nop2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945102,547,510 - 102,560,568 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049367091,215,100 - 1,228,117 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NOP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl564,106,098 - 64,115,579 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1564,106,013 - 64,115,582 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2566,463,609 - 66,473,180 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NOP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1116,590,518 - 6,601,981 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl116,590,642 - 6,601,552 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660631,622,901 - 1,634,416 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_004869399   ⟹   XP_004869456
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248603,273,944 - 3,284,085 (-)NCBI
RefSeq Acc Id: XM_004869400   ⟹   XP_004869457
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248603,273,944 - 3,284,150 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004869456 (Get FASTA)   NCBI Sequence Viewer  
  XP_004869457 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000059740
  ENSHGLP00100035069
GenBank Protein JAO01614 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004869457   ⟸   XM_004869400
- UniProtKB: A0A0N8EUB8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004869456   ⟸   XM_004869399
- UniProtKB: A0A0N8EUB8 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000042932 UniProtKB/TrEMBL
  ENSHGLG00100051669 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000060478 UniProtKB/TrEMBL
  ENSHGLT00100073292 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.150 UniProtKB/TrEMBL
InterPro Fmu/NOL1/Nop2p_CS UniProtKB/TrEMBL
  Methyltr_RsmF_N UniProtKB/TrEMBL
  MeTrfase_RsmB-F_NOP2_cat UniProtKB/TrEMBL
  MeTrfase_RsmB/NOP2 UniProtKB/TrEMBL
  Nop2p UniProtKB/TrEMBL
  RCMT UniProtKB/TrEMBL
  RCMT_NOP2 UniProtKB/TrEMBL
  SAM-dependent_MTases UniProtKB/TrEMBL
NCBI Gene Nop2 ENTREZGENE
PANTHER 28S RRNA (CYTOSINE(4447)-C(5))-METHYLTRANSFERASE-RELATED UniProtKB/TrEMBL
  PTHR22807 UniProtKB/TrEMBL
Pfam Methyltr_RsmB-F UniProtKB/TrEMBL
  Methyltr_RsmF_N UniProtKB/TrEMBL
PRINTS RCMTFAMILY UniProtKB/TrEMBL
  RCMTNOP2 UniProtKB/TrEMBL
PROSITE NOL1_NOP2_SUN UniProtKB/TrEMBL
  SAM_MT_RSMB_NOP UniProtKB/TrEMBL
Superfamily-SCOP SSF53335 UniProtKB/TrEMBL
UniProt A0A0N8EUB8 ENTREZGENE, UniProtKB/TrEMBL