NOP2 (NOP2 nucleolar protein) - Rat Genome Database

Name: NOP2
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: NOP2 (NOP2 nucleolar protein) Sus scrofa

Analyze

Symbol:

NOP2

Name:

NOP2 nucleolar protein

RGD ID:

14275006

Description:

ENCODES a protein that exhibits methyltransferase activity (inferred); RNA binding (inferred); RNA methyltransferase activity (inferred); INVOLVED IN blastocyst formation (ortholog); ribosomal large subunit biogenesis (ortholog); rRNA processing (ortholog); ASSOCIATED WITH Hyperphosphatemic Familial Tumoral Calcinosis 1 (ortholog); lymphoproliferative syndrome 2 (ortholog); peroxisome biogenesis disorder 2B (ortholog); FOUND IN nucleus (ortholog); INTERACTS WITH deoxynivalenol

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

NOP2 nucleolar protein homolog; probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	NOP2 (NOP2 nucleolar protein)	HGNC	EggNOG, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Nop2 (NOP2 nucleolar protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Nop2 (NOP2 nucleolar protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Nop2 (NOP2 nucleolar protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	NOP2 (NOP2 nucleolar protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	NOP2 (NOP2 nucleolar protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Nop2 (NOP2 nucleolar protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	NOP2 (NOP2 nucleolar protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Nop2 (NOP2 nucleolar protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	64,106,098 - 64,115,579 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	5	64,106,013 - 64,115,582 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	66,463,609 - 66,473,180 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Hyperphosphatemic Familial Tumoral Calcinosis 1 (ISO)

lymphoproliferative syndrome 2 (ISO)

peroxisome biogenesis disorder 2B (ISO)

Temtamy syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

deoxynivalenol (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

blastocyst formation (ISO)

maturation of LSU-rRNA (IBA,IEA)

methylation (IEA)

positive regulation of cell population proliferation (IEA)

regulation of signal transduction by p53 class mediator (IEA)

ribosomal large subunit biogenesis (ISO)

ribosome biogenesis (IEA)

RNA methylation (IEA)

RNA processing (IEA)

rRNA base methylation (IBA,IEA)

rRNA processing (ISO)

tRNA methylation (IEA)

Cellular Component

nucleolus (IBA,IEA)

nucleus (ISO)

Molecular Function

methyltransferase activity (IEA)

protein binding (ISO)

RNA binding (IEA)

RNA methyltransferase activity (IEA)

rRNA (cytosine-C5-)-methyltransferase activity (IBA,IEA)

S-adenosylmethionine-dependent methyltransferase activity (IEA)

tRNA (cytidine-5-)-methyltransferase activity (IEA)

References

Additional References at PubMed

PMID:14681463	PMID:17145712	PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

NOP2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	64,106,098 - 64,115,579 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	5	64,106,013 - 64,115,582 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	66,463,609 - 66,473,180 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NOP2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	6,556,871 - 6,568,291 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	6,556,863 - 6,568,691 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	12	6,666,037 - 6,677,457 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	6,536,298 - 6,547,741 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	12	6,536,289 - 6,547,345	NCBI
Celera	12	8,282,899 - 8,294,342 (-)	NCBI		Celera
Cytogenetic Map	12	p13.31	NCBI
HuRef	12	6,520,171 - 6,531,576 (-)	NCBI		HuRef
CHM1_1	12	6,665,044 - 6,676,501 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	12	6,567,230 - 6,578,651 (-)	NCBI		T2T-CHM13v2.0

Nop2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	125,108,829 - 125,121,716 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	125,108,872 - 125,121,716 (+)	Ensembl		GRCm39 Ensembl
GRCm38	6	125,131,883 - 125,144,753 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	125,131,909 - 125,144,753 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	125,081,901 - 125,094,771 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	6	125,097,558 - 125,110,372 (+)	NCBI		MGSCv36	mm8
Celera	6	126,801,863 - 126,814,607 (+)	NCBI		Celera
Cytogenetic Map	6	F2	NCBI
cM Map	6	59.32	NCBI

Nop2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	159,618,894 - 159,630,697 (+)	NCBI		GRCr8
mRatBN7.2	4	157,932,731 - 157,944,462 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	157,932,716 - 157,944,459 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	4	164,161,797 - 164,173,528 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	159,944,712 - 159,956,443 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	158,580,682 - 158,592,424 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	157,646,759 - 157,658,502 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	157,647,082 - 157,658,390 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	224,663,955 - 224,675,686 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	161,252,117 - 161,264,321 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	4	161,497,375 - 161,509,257 (+)	NCBI
Celera	4	146,669,575 - 146,681,484 (+)	NCBI		Celera
Cytogenetic Map	4	q42	NCBI

Nop2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955413	4,180,573 - 4,190,490 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955413	4,180,463 - 4,190,827 (-)	NCBI	ChiLan1.0	ChiLan1.0

NOP2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	12,118,734 - 12,130,299 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	12,115,491 - 12,127,002 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	6,687,763 - 6,699,234 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	6,606,036 - 6,617,260 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	6,606,036 - 6,617,260 (-)	Ensembl	panpan1.1		panPan2

NOP2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	27	38,441,259 - 38,453,946 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	27	38,441,690 - 38,453,824 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	27	8,162,718 - 8,175,429 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	27	38,795,791 - 38,808,510 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	27	38,795,860 - 38,808,510 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	27	38,667,821 - 38,680,527 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	27	38,709,346 - 38,722,054 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	27	7,641,408 - 7,654,127 (-)	NCBI		UU_Cfam_GSD_1.0

Nop2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	102,547,510 - 102,560,568 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936709	1,215,100 - 1,228,117 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NOP2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	6,590,518 - 6,601,981 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	6,590,642 - 6,601,552 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666063	1,622,901 - 1,634,416 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Nop2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624860	3,273,944 - 3,284,150 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in NOP2
178 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	hemolymphoid system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system
High
Medium				1				1
Low	10	4	3	4	2	23	2	2	3
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001244246	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013987297	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000037	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK343646	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK343669	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK343749	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK343854	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK345763	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK391033	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK393604	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK394992	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK399106	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU914489	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GFLN01050694	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSSCT00000000758 ⟹ ENSSSCP00000000742

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	5	64,106,098 - 64,115,579 (+)	Ensembl

RefSeq Acc Id:

NM_001244246 ⟹ NP_001231175

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	5	64,106,109 - 64,115,582 (+)	NCBI

Sequence:

show sequence

AGACGTTCCCGTGGTGTGGCGTCGGAGCGCCAGCCCCGCACCACACGTGGAGTGCTGTCGCTGC
TTCCTAGGGCCTTCTCGGGACTGGACCCGCTTCCAGTACCATGGGGCGCAAATTGGACCCTACG
AAGGAGAAACGCGGGCCGGGCCGAAAGGCCCGAAAGCAGAAAGGTGCTGAGACCGAACTCGTCA
GATTCTTGCCTGCAGCTGGTGATGAAAATTCCAAGAGGCTGTCCAGTCGTGCTCGAAAGAGGGC
AGCCAAGAGGAGGTTGGGCTCTGCTGAAGTCCGTGAGACAAATAAATCCCCTGGGGCCAGACCA
TTGCCTGGAAAGCTACCAAAAGGAGCCGTCCAGACACCGAGTAAGAAGGGAGCCCTGTCCTTAT
TTAATGCTGCTCAAGGCAAGAAGCGCCCAGCATCAGCCTATAGCAGTGAGGAGGAGGGAGAGGA
GGAAGACTCTGAAGAGGGTGGTGTGGTGAACGAGGGGGACCTCTGGGGCTCTGAGGACAGTGAT
GCCGATATGGTAGATGACTATGGAGCCAACTCCAGTTCAGAGGACGAAGAAGAGGATGACAGTG
AAGAGTTGCTGCCCATTGAAAGGGCTGCTCGAAAGCAGAAGGCCCAGGAAGCTGTTACTGGGAG
CCAGTGGAGTGAGGAGGAGACTGAGGAAGAGGAGGAGGAATCCCCTGAGTCAGGCCCTAGAGAA
GATGATGAGACAGAAGGGGGCCTCCAGATCAATGTGGATGAGGAGGAGCCTTTTGTACTGCCCC
TTGCTGGAGAGATGGAGCAGGATGCCCAGGCTCCAGACTTGCAGCGAGTTCACAAGCGCATCCA
AGATATAGTGGGAGTGTTGCGTGATTTTGGGACTCAGCGGGAGGAGGGTCGGTCTCGTGCTGAA
TATCTGCAGCGGCTTCGGAAGGATTTGGCCACTTATTACTCCTACGGAGACTTTCTCCTTGGCA
AGCTCATGGACCTCTTCCCTCTGTCTGAGCTGGTGGAGTTCTTGGAAGCTAATGAGGTGCCTCG
GCCCATCACCCTCAGGACCAATACGTTGAAGACCCGGCGCCGAGACCTTGCTCAGGCACTAATC
AATCGTGGGGTTAACCTGGATCCCCTGGGCAAGTGGTCAAAGACTGGACTCGTGGTGTATGATT
CCTCGGTGCCCATTGGTGCTACTCCTGAGTACTTGGCTGGGCACTACATGCTACAGGGTGCGTC
CAGCATGTTGCCTGTCATGGCCTTGGCGCCCCAGGAACACGAGCGGATTCTGGACATGTGTTGT
GCCCCTGGAGGAAAGACCAGCTACATTGCCCAGCTCATGAAGAACACGGGTGTGATTCTCGCCA
ACGATGCCAATGCTGAGCGGCTCAAGAGTGTCGTGGGCAACTTGCACCGGCTGGGAGTCACCAA
CACCATCATCAGCAACTACGATGGGCGCCAGTTCCCCAAGGTGGTGGGGGGCTTTGACCGAGTC
CTGCTGGATGCTCCTTGCAGTGGCACTGGGATCATCTCCAAGGACCCAGCTGTGAAGACTAACA
AGGATGAGAAGGACATTCTGCGCTGTGCTCACCTTCAGAAGGAGCTGCTCCTGAGTGCTATCGA
CTCTGTCAGTGCCACCTCCAAGACAGGAGGCTACCTTGTGTACTGCACCTGCTCCATCACGGTG
GAAGAGAATGAGTGGGTGGTAGACTACGCACTGAAGAAGAGGAATGTGCGGCTTGTGCCCACTG
GCCTGGACTTCGGCCAGGAGGGCTTTACCCGCTTCCGGGAAAGGCGCTTCCACCCCACTCTGCG
TTCTACCCGCCGCTTCTACCCTCACACCCACAACATGGATGGTTTCTTTATTGCCAAGTTCAAG
AAGTTCTCCAATTCTATCCCCCAGTCCCAAACAGGAAATTCTGCAACATCAACCCCTACAAACC
CAGACTTGCCCAGCCCGAAAGGGGAGGTGACTCCCAAGCCTGAGCGCAGCAGCCAGCCTGCCAA
GAAGGCCAGAGTGGCTGTGCAAGCAAAGCAGCGGCTGCAGAAACGGCAACTTCCCAAGAAGGCT
TCTTTCCAAAAGCAGAATGGCGTCTCCAAAGGGACAGGCTCAGAATTGTCCACTGTGTCTTCTG
TCACAAAGGTCCAACCTTCCTCCAAGCTCCAGGATAGCAAGCAGCCAGCTGAGAAAGCAGTAGT
GGTCAGGGAACCAAAGGTGGCTGGGAGACTAAAACAGTCACCCAAACTGCAGTCCTCCAAGAAA
GTTGCCTTCCCAAAGCAGTGTGTTCCTCCCAAGGGCATGGACCCAGAAATCCCTCCTGTGCCAT
CCCTCTCCAAGACCCAGGATGCTTTCAAGCCTGAGGACTGCAATCAGCCCCTTGGAAACACCAC
CACAGGGGCTGAGAAGGTAAAGCAGCAGTTACCAGAGCAATCTTTCAAGAAAACTGCCTTCCAG
AAACAGAATGGCACCCCCAAGGGACCTAAGACTCCCACCATGTCCCCTCGCAGTTCTAGCAGGC
CCCCACCAGCGAAGAGGAGAAAATCGCAGTCCAGAGGCAGCAGCCAACCACTGCCGTCTTCAGT
GGATGGTTGAACTAGACTGGGGTGGTTCATTGCCATTGTTACTAGGTTGGAGCTCTTACCTCCG
TGAGGATGGCTTTCCCACCGTGGATGTGAAATTTAATACACAATTTGCAATCTTGCC

hide sequence

RefSeq Acc Id:

XM_013987297 ⟹ XP_013842751

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	5	64,106,013 - 64,115,581 (+)	NCBI

Sequence:

show sequence

CCCCGCGCGGCCGCGCGAATGAAACTTCCGGCTTCCGCGGCGGACGGGAAGCCCGGAAGAGGCG
GGGCCTCAGCGGGCGCGCTGTGCGCTTGCGCGAGACGTTCCCGTGGTGTGGCGTCGGAGCGCCA
GCCCCGCACCACACGTGGAGTGCTGTCGCTGCTTCCTAGGGCCTTCTCGGGACTGGACCCGCTT
CCAGTACCATGGGGCGCAAATTGGACCCTACGAAGGAGAAACGCGGGCCGGGCCGAAAGGCCCG
AAAGCAGAAAGGTGCTGAGACCGAACTCGTCAGATTCTTGCCTGCAGCTGGTGATGAAAATTCC
AAGAGGCTGTCCAGTCGTGCTCGAAAGAGCCAAGAGGAGGTTGGGCTCTGCTGAAGTCCGTGAG
ACAAATAAATCCCCTGGGGCCAGACCATTGCCTGGAAAGCTACCAAAAGGAGCCGTCCAGACAC
CGAGTAAGAAGGGAGCCCTGTCCTTATTTAATGCTGCTCAAGGCAAGAAGCGCCCAGCATCAGC
CTATAGCAGTGAGGAGGAGGGAGAGGAGGAAGACTCTGAAGAGGGTGGTGTGGTGAACGAGGGG
GACCTCTGGGGCTCTGAGGACAGTGATGCCGATATGGTAGATGACTATGGAGCCAACTCCAGTT
CAGAGGACGAAGAAGAGGATGACAGTGAAGAGTTGCTGCCCATTGAAAGGGCTGCTCGAAAGCA
GAAGGCCCAGGAAGCTGTTACTGGGAGCCAGTGGAGTGAGGAGGAGACTGAGGAAGAGGAGGAG
GAATCCCCTGAGTCAGGCCCTAGAGAAGATGATGAGACAGAAGGGGGCCTCCAGATCAATGTGG
ATGAGGAGGAGCCTTTTGTACTGCCCCTTGCTGGAGAGATGGAGCAGGATGCCCAGGCTCCAGA
CTTGCAGCGAGTTCACAAGCGCATCCAAGATATAGTGGGAGTGTTGCGTGATTTTGGGACTCAG
CGGGAGGAGGGTCGGTCTCGTGCTGAATATCTGCAGCGGCTTCGGAAGGATTTGGCCACTTATT
ACTCCTACGGAGACTTTCTCCTTGGCAAGCTCATGGACCTCTTCCCTCTGTCTGAGCTGGTGGA
GTTCTTGGAAGCTAATGAGGTGCCTCGGCCCATCACCCTCAGGACCAATACGTTGAAGACCCGG
CGCCGAGACCTTGCTCAGGCACTAATCAATCGTGGGGTTAACCTGGATCCCCTGGGCAAGTGGT
CAAAGACTGGACTCGTGGTGTATGATTCCTCGGTGCCCATTGGTGCTACTCCTGAGTACTTGGC
TGGGCACTACATGCTACAGGGTGCGTCCAGCATGTTGCCTGTCATGGCCTTGGCGCCCCAGGAA
CACGAGCGGATTCTGGACATGTGTTGTGCCCCTGGAGGAAAGACCAGCTACATTGCCCAGCTCA
TGAAGAACACGGGTGTGATTCTCGCCAACGATGCCAATGCTGAGCGGCTCAAGAGTGTCGTGGG
CAACTTGCACCGGCTGGGAGTCACCAACACCATCATCAGCAACTACGATGGGCGCCAGTTCCCC
AAGGTGGTGGGGGGCTTTGACCGAGTCCTGCTGGATGCTCCTTGCAGTGGCACTGGGATCATCT
CCAAGGACCCAGCTGTGAAGACTAACAAGGATGAGAAGGACATTCTGCGCTGTGCTCACCTTCA
GAAGGAGCTGCTCCTGAGTGCTATCGACTCTGTCAGTGCCACCTCCAAGACAGGAGGCTACCTT
GTGTACTGCACCTGCTCCATCACGGTGGAAGAGAATGAGTGGGTGGTAGACTACGCACTGAAGA
AGAGGAATGTGCGGCTTGTGCCCACTGGCCTGGACTTCGGCCAGGAGGGCTTTACCCGCTTCCG
GGAAAGGCGCTTCCACCCCACTCTGCGTTCTACCCGCCGCTTCTACCCTCACACCCACAACATG
GATGGTTTCTTTATTGCCAAGTTCAAGAAGTTCTCCAATTCTATCCCCCAGTCCCAAACAGGAA
ATTCTGCAACATCAACCCCTACAAACCCAGACTTGCCCAGCCCGAAAGGGGAGGTGACTCCCAA
GCCTGAGCGCAGCAGCCAGCCTGCCAAGAAGGCCAGAGTGGCTGTGCAAGCAAAGCAGCGGCTG
CAGAAACGGCAACTTCCCAAGAAGGCTTCTTTCCAAAAGCAGAATGGCGTCTCCAAAGGGACAG
GCTCAGAATTGTCCACTGTGTCTTCTGTCACAAAGGTCCAACCTTCCTCCAAGCTCCAGGATAG
CAAGCAGCCAGCTGAGAAAGCAGTAGTGGTCAGGGAACCAAAGGTGGCTGGGAGACTAAAACAG
TCACCCAAACTGCAGTCCTCCAAGAAAGTTGCCTTCCCAAAGCAGTGTGTTCCTCCCAAGGGCA
TGGACCCAGAAATCCCTCCTGTGCCATCCCTCTCCAAGACCCAGGATGCTTTCAAGCCTGAGGA
CTGCAATCAGCCCCTTGGAAACACCACCACAGGGGCTGAGAAGGTAAAGCAGCAGTTACCAGAG
CAATCTTTCAAGAAAACTGCCTTCCAGAAACAGAATGGCACCCCCAAGGGACCTAAGACTCCCA
CCATGTCCCCTCGCAGTTCTAGCAGGCCCCCACCAGCGAAGAGGAGAAAATCGCAGTCCAGAGG
CAGCAGCCAACCACTGCCGTCTTCAGTGGATGGTTGAACTAGACTGGGGTGGTTCATTGCCATT
GTTACTAGGTTGGAGCTCTTACCTCCGTGAGGATGGCTTTCCCACCGTGGATGTGAAATTTAAT
ACACAATTTGCAATCTTGC

hide sequence

Protein Sequences


Protein RefSeqs	NP_001231175	(Get FASTA)	NCBI Sequence Viewer
	XP_013842751	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000000742
	ENSSSCP00000000742.4
	ENSSSCP00005037167.1
	ENSSSCP00015037539.1
	ENSSSCP00030023923.1
	ENSSSCP00035048681.1
	ENSSSCP00040037669.1
	ENSSSCP00045019853.1
	ENSSSCP00055048673.1
	ENSSSCP00060024091.1
	ENSSSCP00070032858.1

RefSeq Acc Id:	XP_013842751 ⟸ XM_013987297
- Peptide Label:	isoform X1
- UniProtKB:	A0A4X1UVU6 (UniProtKB/TrEMBL), A0A8D1SIB1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MKLPASAADGKPGRGGASAGALCACARRSRGVASERQPRTTRGVLSLLPRAFSGLDPLPVPWGA NWTLRRRNAGRAERPESRKVLRPNSSDSCLQLVMKIPRGCPVVLERAKRRLGSAEVRETNKSPG ARPLPGKLPKGAVQTPSKKGALSLFNAAQGKKRPASAYSSEEEGEEEDSEEGGVVNEGDLWGSE DSDADMVDDYGANSSSEDEEEDDSEELLPIERAARKQKAQEAVTGSQWSEEETEEEEEESPESG PREDDETEGGLQINVDEEEPFVLPLAGEMEQDAQAPDLQRVHKRIQDIVGVLRDFGTQREEGRS RAEYLQRLRKDLATYYSYGDFLLGKLMDLFPLSELVEFLEANEVPRPITLRTNTLKTRRRDLAQ ALINRGVNLDPLGKWSKTGLVVYDSSVPIGATPEYLAGHYMLQGASSMLPVMALAPQEHERILD MCCAPGGKTSYIAQLMKNTGVILANDANAERLKSVVGNLHRLGVTNTIISNYDGRQFPKVVGGF DRVLLDAPCSGTGIISKDPAVKTNKDEKDILRCAHLQKELLLSAIDSVSATSKTGGYLVYCTCS ITVEENEWVVDYALKKRNVRLVPTGLDFGQEGFTRFRERRFHPTLRSTRRFYPHTHNMDGFFIA KFKKFSNSIPQSQTGNSATSTPTNPDLPSPKGEVTPKPERSSQPAKKARVAVQAKQRLQKRQLP KKASFQKQNGVSKGTGSELSTVSSVTKVQPSSKLQDSKQPAEKAVVVREPKVAGRLKQSPKLQS SKKVAFPKQCVPPKGMDPEIPPVPSLSKTQDAFKPEDCNQPLGNTTTGAEKVKQQLPEQSFKKT AFQKQNGTPKGPKTPTMSPRSSSRPPPAKRRKSQSRGSSQPLPSSVDG hide sequence

RefSeq Acc Id:

NP_001231175 ⟸ NM_001244246

- UniProtKB:

F1SLR6 (UniProtKB/TrEMBL), A0A4X1UVU6 (UniProtKB/TrEMBL), A0A8D1SIB1 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MGRKLDPTKEKRGPGRKARKQKGAETELVRFLPAAGDENSKRLSSRARKRAAKRRLGSAEVRET
NKSPGARPLPGKLPKGAVQTPSKKGALSLFNAAQGKKRPASAYSSEEEGEEEDSEEGGVVNEGD
LWGSEDSDADMVDDYGANSSSEDEEEDDSEELLPIERAARKQKAQEAVTGSQWSEEETEEEEEE
SPESGPREDDETEGGLQINVDEEEPFVLPLAGEMEQDAQAPDLQRVHKRIQDIVGVLRDFGTQR
EEGRSRAEYLQRLRKDLATYYSYGDFLLGKLMDLFPLSELVEFLEANEVPRPITLRTNTLKTRR
RDLAQALINRGVNLDPLGKWSKTGLVVYDSSVPIGATPEYLAGHYMLQGASSMLPVMALAPQEH
ERILDMCCAPGGKTSYIAQLMKNTGVILANDANAERLKSVVGNLHRLGVTNTIISNYDGRQFPK
VVGGFDRVLLDAPCSGTGIISKDPAVKTNKDEKDILRCAHLQKELLLSAIDSVSATSKTGGYLV
YCTCSITVEENEWVVDYALKKRNVRLVPTGLDFGQEGFTRFRERRFHPTLRSTRRFYPHTHNMD
GFFIAKFKKFSNSIPQSQTGNSATSTPTNPDLPSPKGEVTPKPERSSQPAKKARVAVQAKQRLQ
KRQLPKKASFQKQNGVSKGTGSELSTVSSVTKVQPSSKLQDSKQPAEKAVVVREPKVAGRLKQS
PKLQSSKKVAFPKQCVPPKGMDPEIPPVPSLSKTQDAFKPEDCNQPLGNTTTGAEKVKQQLPEQ
SFKKTAFQKQNGTPKGPKTPTMSPRSSSRPPPAKRRKSQSRGSSQPLPSSVDG

hide sequence

RefSeq Acc Id:

ENSSSCP00000000742 ⟸ ENSSSCT00000000758

Protein Domains

SAM-dependent MTase RsmB/NOP-type

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000000696	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCG00005037009	UniProtKB/TrEMBL
	ENSSSCG00015067369	UniProtKB/TrEMBL
	ENSSSCG00030037476	UniProtKB/TrEMBL
	ENSSSCG00035080978	UniProtKB/TrEMBL
	ENSSSCG00040062661	UniProtKB/TrEMBL
	ENSSSCG00045016661	UniProtKB/TrEMBL
	ENSSSCG00055030489	UniProtKB/TrEMBL
	ENSSSCG00060041498	UniProtKB/TrEMBL
	ENSSSCG00070019777	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000000758	ENTREZGENE
	ENSSSCT00000000758.5	UniProtKB/TrEMBL
	ENSSSCT00005060208.1	UniProtKB/TrEMBL
	ENSSSCT00015091715.1	UniProtKB/TrEMBL
	ENSSSCT00030052443.1	UniProtKB/TrEMBL
	ENSSSCT00035111244.1	UniProtKB/TrEMBL
	ENSSSCT00040085999.1	UniProtKB/TrEMBL
	ENSSSCT00045028701.1	UniProtKB/TrEMBL
	ENSSSCT00055060742.1	UniProtKB/TrEMBL
	ENSSSCT00060056357.1	UniProtKB/TrEMBL
	ENSSSCT00070039240.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.150	UniProtKB/TrEMBL
InterPro	Fmu/NOL1/Nop2p_CS	UniProtKB/TrEMBL
	Methyltr_RsmF_N	UniProtKB/TrEMBL
	MeTrfase_RsmB-F_NOP2_cat	UniProtKB/TrEMBL
	MeTrfase_RsmB/NOP2	UniProtKB/TrEMBL
	Nop2p	UniProtKB/TrEMBL
	RCMT	UniProtKB/TrEMBL
	RCMT_NOP2	UniProtKB/TrEMBL
	SAM-dependent_MTases	UniProtKB/TrEMBL
KEGG Report	ssc:100516080	UniProtKB/TrEMBL
NCBI Gene	NOP2	ENTREZGENE
PANTHER	28S RRNA (CYTOSINE(4447)-C(5))-METHYLTRANSFERASE-RELATED	UniProtKB/TrEMBL
	PTHR22807	UniProtKB/TrEMBL
Pfam	Methyltr_RsmB-F	UniProtKB/TrEMBL
	Methyltr_RsmF_N	UniProtKB/TrEMBL
PRINTS	RCMTFAMILY	UniProtKB/TrEMBL
	RCMTNOP2	UniProtKB/TrEMBL
PROSITE	NOL1_NOP2_SUN	UniProtKB/TrEMBL
	SAM_MT_RSMB_NOP	UniProtKB/TrEMBL
Superfamily-SCOP	SSF53335	UniProtKB/TrEMBL
UniProt	A0A4X1UVU6	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D0WPG5_PIG	UniProtKB/TrEMBL
	A0A8D1KIB6_PIG	UniProtKB/TrEMBL
	A0A8D1SIB1	ENTREZGENE, UniProtKB/TrEMBL
	F1SLR6	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:103306	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar