Camk2b (calcium/calmodulin dependent protein kinase II beta) - Rat Genome Database

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Gene: Camk2b (calcium/calmodulin dependent protein kinase II beta) Heterocephalus glaber
Analyze
Symbol: Camk2b
Name: calcium/calmodulin dependent protein kinase II beta
RGD ID: 18899787
Description: ENCODES a protein that exhibits calcium-dependent protein serine/threonine kinase activity (ortholog); calmodulin-dependent protein kinase activity (ortholog); identical protein binding (ortholog); INVOLVED IN activation of meiosis involved in egg activation (ortholog); apoptotic signaling pathway (ortholog); calcium ion transport (ortholog); PARTICIPATES IN calcium/calmodulin dependent kinase 2 signaling pathway; p38 MAPK signaling pathway; type II interferon signaling pathway; ASSOCIATED WITH Apnea (ortholog); autism spectrum disorder (ortholog); autosomal dominant intellectual developmental disorder 54 (ortholog); FOUND IN calcium- and calmodulin-dependent protein kinase complex (ortholog); cytosol (ortholog); dendrite (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: calcium/calmodulin-dependent protein kinase type II subunit beta
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247407,750,245 - 7,831,454 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247407,750,327 - 7,828,891 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Camk2b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247407,750,245 - 7,831,454 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247407,750,327 - 7,828,891 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
CAMK2B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38744,217,154 - 44,326,013 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl744,210,019 - 44,334,577 (-)EnsemblGRCh38hg38GRCh38
GRCh37744,256,753 - 44,365,193 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36744,225,416 - 44,331,749 (-)NCBINCBI36Build 36hg18NCBI36
Build 34744,032,136 - 44,138,464NCBI
Celera744,354,715 - 44,422,313 (-)NCBICelera
Cytogenetic Map7p13NCBI
HuRef744,142,028 - 44,208,379 (-)ENTREZGENEHuRef
CHM1_1744,260,608 - 44,369,178 (-)NCBICHM1_1
T2T-CHM13v2.0744,375,741 - 44,485,432 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2744,296,255 - 44,404,749 (-)ENTREZGENE
Camk2b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39115,919,642 - 6,016,401 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl115,919,644 - 6,016,362 (-)EnsemblGRCm39 Ensembl
GRCm38115,969,629 - 6,066,357 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl115,969,644 - 6,066,362 (-)EnsemblGRCm38mm10GRCm38
MGSCv37115,869,645 - 5,965,751 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36115,869,675 - 5,965,751 (-)NCBIMGSCv36mm8
Celera116,461,702 - 6,553,628 (-)NCBICelera
Cytogenetic Map11A1NCBI
cM Map113.89NCBI
Camk2b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81485,059,166 - 85,148,121 (-)NCBIGRCr8
mRatBN7.21480,845,206 - 80,934,172 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1480,845,238 - 80,933,994 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1485,247,252 - 85,335,996 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01486,487,349 - 86,576,085 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01482,936,663 - 83,025,404 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01486,208,876 - 86,297,727 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1486,208,901 - 86,297,652 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01486,893,062 - 86,982,256 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41486,632,686 - 86,721,281 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11486,653,834 - 86,740,406 (-)NCBI
Celera1479,728,956 - 79,817,594 (-)NCBICelera
Cytogenetic Map14q21NCBI
Camk2b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554567,713,552 - 7,760,207 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554567,711,583 - 7,760,506 (+)NCBIChiLan1.0ChiLan1.0
CAMK2B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2649,128,517 - 49,238,128 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1797,453,257 - 97,562,867 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0744,930,859 - 45,040,078 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1745,001,240 - 45,110,499 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl745,001,267 - 45,110,342 (-)Ensemblpanpan1.1panPan2
CAMK2B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_Tasha162,142,154 - 2,219,094 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01614,642,707 - 14,719,698 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1614,642,688 - 14,732,697 (+)EnsemblROS_Cfam_1.0 Ensembl
UNSW_CanFamBas_1.01614,274,291 - 14,351,161 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01614,254,459 - 14,331,424 (+)NCBIUU_Cfam_GSD_1.0
Camk2b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511899,971,714 - 100,066,726 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647819,180,726 - 19,278,920 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647819,183,493 - 19,278,457 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CAMK2B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1850,861,466 - 50,956,225 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11850,862,225 - 50,956,263 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21855,764,825 - 55,851,601 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CAMK2B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12114,342,751 - 14,451,274 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2114,342,892 - 14,451,282 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660628,066,177 - 8,195,979 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000022351   ⟹   ENSHGLP00000022140
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247407,750,245 - 7,831,454 (+)Ensembl
RefSeq Acc Id: ENSHGLT00000022352   ⟹   ENSHGLP00000022141
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247407,750,245 - 7,831,454 (+)Ensembl
RefSeq Acc Id: ENSHGLT00000022353   ⟹   ENSHGLP00000022142
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247407,750,245 - 7,831,454 (+)Ensembl
RefSeq Acc Id: ENSHGLT00000022354   ⟹   ENSHGLP00000022143
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247407,750,428 - 7,828,556 (+)Ensembl
RefSeq Acc Id: ENSHGLT00000022355   ⟹   ENSHGLP00000022144
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247407,750,428 - 7,828,556 (+)Ensembl
RefSeq Acc Id: ENSHGLT00000022356   ⟹   ENSHGLP00000022145
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247407,750,428 - 7,828,556 (+)Ensembl
RefSeq Acc Id: ENSHGLT00000022357   ⟹   ENSHGLP00000022146
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247407,750,428 - 7,828,556 (+)Ensembl
RefSeq Acc Id: ENSHGLT00000022358   ⟹   ENSHGLP00000022147
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247407,750,428 - 7,828,556 (+)Ensembl
RefSeq Acc Id: XM_004839914   ⟹   XP_004839971
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247407,750,327 - 7,828,891 (+)NCBI
RefSeq Acc Id: XM_004839915   ⟹   XP_004839972
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247407,750,328 - 7,828,891 (+)NCBI
RefSeq Acc Id: XM_004839916   ⟹   XP_004839973
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247407,750,327 - 7,828,891 (+)NCBI
RefSeq Acc Id: XM_004839917   ⟹   XP_004839974
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247407,750,327 - 7,828,891 (+)NCBI
RefSeq Acc Id: XM_004839919   ⟹   XP_004839976
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247407,750,327 - 7,828,891 (+)NCBI
RefSeq Acc Id: XM_004839920   ⟹   XP_004839977
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247407,801,951 - 7,828,891 (+)NCBI
RefSeq Acc Id: XM_021254280   ⟹   XP_021109939
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247407,750,327 - 7,828,891 (+)NCBI
RefSeq Acc Id: XM_021254282   ⟹   XP_021109941
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247407,750,327 - 7,828,891 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_004839971   ⟸   XM_004839914
- Peptide Label: isoform X8
- UniProtKB: A0A0P6JUM5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004839973   ⟸   XM_004839916
- Peptide Label: isoform X2
- UniProtKB: A0A0P6JUM5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004839974   ⟸   XM_004839917
- Peptide Label: isoform X3
- UniProtKB: A0A0P6JUM5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004839976   ⟸   XM_004839919
- Peptide Label: isoform X5
- UniProtKB: A0A0P6JUM5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021109939   ⟸   XM_021254280
- Peptide Label: isoform X4
- UniProtKB: A0A0P6JUM5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021109941   ⟸   XM_021254282
- Peptide Label: isoform X6
- UniProtKB: A0A0P6JUM5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004839972   ⟸   XM_004839915
- Peptide Label: isoform X1
- UniProtKB: A0A0P6JUM5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004839977   ⟸   XM_004839920
- Peptide Label: isoform X7
- UniProtKB: A0A0P6JUM5 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000022141   ⟸   ENSHGLT00000022352
RefSeq Acc Id: ENSHGLP00000022147   ⟸   ENSHGLT00000022358
RefSeq Acc Id: ENSHGLP00000022143   ⟸   ENSHGLT00000022354
RefSeq Acc Id: ENSHGLP00000022142   ⟸   ENSHGLT00000022353
RefSeq Acc Id: ENSHGLP00000022146   ⟸   ENSHGLT00000022357
RefSeq Acc Id: ENSHGLP00000022144   ⟸   ENSHGLT00000022355
RefSeq Acc Id: ENSHGLP00000022145   ⟸   ENSHGLT00000022356
RefSeq Acc Id: ENSHGLP00000022140   ⟸   ENSHGLT00000022351


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000015797 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000022352 ENTREZGENE
  ENSHGLT00000022353 ENTREZGENE
  ENSHGLT00000022354 ENTREZGENE
  ENSHGLT00000022356 ENTREZGENE
  ENSHGLT00000022358 ENTREZGENE
Gene3D-CATH 3.10.450.50 UniProtKB/TrEMBL
  6.10.140.620 UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro Ca/CaM-dep_prot_kinase-assoc UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  NTF2-like_dom_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
NCBI Gene Camk2b ENTREZGENE
PANTHER CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II SUBUNIT BETA UniProtKB/TrEMBL
  SERINE/THREONINE-PROTEIN KINASE UniProtKB/TrEMBL
Pfam CaMKII_AD UniProtKB/TrEMBL
  Pkinase UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP SSF54427 UniProtKB/TrEMBL
  SSF56112 UniProtKB/TrEMBL
UniProt A0A0P6JUM5 ENTREZGENE, UniProtKB/TrEMBL