DHRS1 (dehydrogenase/reductase 1) - Rat Genome Database

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Gene: DHRS1 (dehydrogenase/reductase 1) Chlorocebus sabaeus
Analyze
Symbol: DHRS1
Name: dehydrogenase/reductase 1
RGD ID: 18708430
Description: ENCODES a protein that exhibits carbonyl reductase (NADPH) activity (inferred); oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (inferred); ASSOCIATED WITH autism spectrum disorder (ortholog); Brain-Lung-Thyroid Syndrome (ortholog); lysinuric protein intolerance (ortholog); FOUND IN endoplasmic reticulum (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: dehydrogenase/reductase SDR family member 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1241,273,717 - 1,282,761 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl241,273,659 - 1,282,812 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603612,958,265 - 12,967,291 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
DHRS1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1241,273,717 - 1,282,761 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl241,273,659 - 1,282,812 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603612,958,265 - 12,967,291 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
DHRS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381424,290,598 - 24,299,780 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1424,290,598 - 24,299,780 (-)EnsemblGRCh38hg38GRCh38
GRCh371424,759,804 - 24,768,986 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361423,829,646 - 23,838,506 (-)NCBINCBI36Build 36hg18NCBI36
Build 341423,829,645 - 23,838,506NCBI
Celera144,624,421 - 4,633,663 (-)NCBICelera
Cytogenetic Map14q12NCBI
HuRef144,874,961 - 4,884,201 (-)NCBIHuRef
CHM1_11424,758,405 - 24,767,639 (-)NCBICHM1_1
T2T-CHM13v2.01418,488,942 - 18,498,124 (-)NCBIT2T-CHM13v2.0
Dhrs1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391455,976,477 - 55,983,147 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1455,976,477 - 55,983,147 (-)EnsemblGRCm39 Ensembl
GRCm381455,739,020 - 55,745,684 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1455,739,020 - 55,745,690 (-)EnsemblGRCm38mm10GRCm38
MGSCv371456,357,857 - 56,364,521 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361454,693,091 - 54,699,663 (-)NCBIMGSCv36mm8
Celera1453,544,068 - 53,550,732 (-)NCBICelera
Cytogenetic Map14C3NCBI
cM Map1428.19NCBI
Dhrs1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81533,206,449 - 33,213,776 (-)NCBIGRCr8
mRatBN7.21529,236,522 - 29,243,807 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1529,236,522 - 29,243,838 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1531,082,199 - 31,089,484 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01532,229,411 - 32,236,696 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01530,471,759 - 30,479,044 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01534,424,017 - 34,431,302 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1534,424,016 - 34,431,325 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01538,313,182 - 38,320,490 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41533,900,694 - 33,907,979 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11533,916,395 - 33,923,679 (-)NCBI
Celera1528,812,169 - 28,819,454 (-)NCBICelera
Cytogenetic Map15p13NCBI
Dhrs1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540936,002,576 - 36,009,513 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540936,002,576 - 36,040,595 (+)NCBIChiLan1.0ChiLan1.0
DHRS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21525,645,629 - 25,654,191 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11424,862,121 - 24,871,292 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0145,066,996 - 5,076,229 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11423,190,323 - 23,199,587 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1423,190,323 - 23,199,587 (-)Ensemblpanpan1.1panPan2
DHRS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.184,263,707 - 4,269,453 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl84,263,700 - 4,270,271 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha84,184,055 - 4,191,794 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.084,373,191 - 4,380,933 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl84,373,194 - 4,380,816 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.184,063,544 - 4,071,277 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.084,125,376 - 4,133,107 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.084,387,953 - 4,395,691 (-)NCBIUU_Cfam_GSD_1.0
Dhrs1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864036,123,012 - 36,133,015 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936722256,192 - 265,985 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936722255,977 - 265,980 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DHRS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl774,992,115 - 75,002,148 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1774,992,120 - 75,002,154 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2780,263,079 - 80,273,096 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Dhrs1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248208,204,627 - 8,213,512 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 28
Low 20 32
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_007986337 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCSAT00000014010   ⟹   ENSCSAP00000011991
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl241,273,659 - 1,282,812 (-)Ensembl
RefSeq Acc Id: XM_007986337   ⟹   XP_007984528
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1241,273,717 - 1,282,761 (-)NCBI
Vero_WHO_p1.0NW_02366603612,958,265 - 12,967,291 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007984528 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000011991.1
Reference Protein Sequences
RefSeq Acc Id: XP_007984528   ⟸   XM_007986337
- UniProtKB: A0A0D9RTQ2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000011991   ⟸   ENSCSAT00000014010


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000015914 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000014010.1 UniProtKB/TrEMBL
Gene3D-CATH NAD(P)-binding Rossmann-like Domain UniProtKB/TrEMBL
InterPro NAD(P)-bd_dom_sf UniProtKB/TrEMBL
  SDR_fam UniProtKB/TrEMBL
KEGG Report csab:103228732 UniProtKB/TrEMBL
NCBI Gene DHRS1 ENTREZGENE
PANTHER DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 1 UniProtKB/TrEMBL
  DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 1 UniProtKB/TrEMBL
Pfam adh_short UniProtKB/TrEMBL
PRINTS GDHRDH UniProtKB/TrEMBL
Superfamily-SCOP SSF51735 UniProtKB/TrEMBL
UniProt A0A0D9RTQ2 ENTREZGENE, UniProtKB/TrEMBL