AASS (aminoadipate-semialdehyde synthase)

Gene: AASS (aminoadipate-semialdehyde synthase) Chlorocebus sabaeus

Analyze

Symbol:

AASS

Name:

aminoadipate-semialdehyde synthase

RGD ID:

18682368

Description:

ENCODES a protein that exhibits oxidoreductase activity (inferred); saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity (inferred); saccharopine dehydrogenase (NADP+, L-lysine-forming) activity (inferred); INVOLVED IN L-lysine catabolic process (ortholog); PARTICIPATES IN 2-aminoadipic 2-oxoadipic aciduria pathway; glutaric aciduria type I pathway; hyperlysinemia pathway; ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); genetic disease (ortholog); hyperlysinemia (ortholog); FOUND IN cytoplasm (inferred); intracellular membrane-bounded organelle (inferred); mitochondrion (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

alpha-aminoadipic semialdehyde synthase, mitochondrial

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	21	90,891,781 - 90,959,351 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	21	90,892,023 - 90,959,343 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666042	12,584,431 - 12,655,125 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Chemical and Drug Induced Liver Injury (ISO)

genetic disease (ISO)

hyperlysinemia (ISO)

Lysine Intolerance (ISO)

pleomorphic xanthoastrocytoma (ISO)

Saccharopinuria (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

L-lysine catabolic process (IEA,ISO)

L-lysine catabolic process to acetyl-CoA via saccharopine (IEA)

lysine biosynthetic process via aminoadipic acid (IEA)

lysine catabolic process (IEA)

lysine metabolic process (IEA)

Cellular Component

cytoplasm (IEA)

intracellular membrane-bounded organelle (IEA)

mitochondrion (IEA)

Molecular Function

oxidoreductase activity (IEA)

saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity (IEA)

saccharopine dehydrogenase (NADP+, L-lysine-forming) activity (IEA)

saccharopine dehydrogenase activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

2-aminoadipic 2-oxoadipic aciduria pathway (ISO)

glutaric aciduria type I pathway (ISO)

hyperlysinemia pathway (ISO)

lysine degradation pathway (ISO)

saccharopinuria pathway (ISO)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

AASS
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	21	90,891,781 - 90,959,351 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	21	90,892,023 - 90,959,343 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666042	12,584,431 - 12,655,125 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

AASS
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	7	122,073,549 - 122,144,249 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	7	122,064,583 - 122,144,308 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	7	121,713,603 - 121,784,303 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	121,503,423 - 121,561,112 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	7	121,310,137 - 121,367,827	NCBI
Celera	7	116,522,826 - 116,593,571 (-)	NCBI		Celera
Cytogenetic Map	7	q31.32	NCBI
HuRef	7	116,077,048 - 116,147,810 (-)	NCBI		HuRef
CHM1_1	7	121,646,898 - 121,717,645 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	7	123,389,454 - 123,460,169 (-)	NCBI		T2T-CHM13v2.0
CRA_TCAGchr7v2	7	121,108,272 - 121,179,018 (-)	NCBI

Aass
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	23,072,172 - 23,132,985 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	23,072,172 - 23,132,985 (-)	Ensembl		GRCm39 Ensembl
GRCm38	6	23,072,173 - 23,132,986 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	23,072,173 - 23,132,986 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	23,022,173 - 23,082,986 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	6	23,022,171 - 23,082,975 (-)	NCBI		MGSCv36	mm8
Celera	6	23,117,896 - 23,183,403 (-)	NCBI		Celera
Cytogenetic Map	6	A3.1	NCBI
cM Map	6	10.27	NCBI

Aass
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	52,572,146 - 52,628,811 (-)	NCBI		GRCr8
mRatBN7.2	4	51,606,461 - 51,663,136 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	51,606,462 - 51,663,136 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	4	56,573,037 - 56,636,497 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	52,494,066 - 52,557,519 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	50,935,584 - 50,999,363 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	50,152,005 - 50,208,935 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	50,152,452 - 50,200,328 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	49,938,569 - 49,993,864 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	49,479,938 - 49,539,782 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	4	49,710,958 - 49,806,368 (-)	NCBI
Celera	4	46,798,734 - 46,861,408 (-)	NCBI		Celera
Cytogenetic Map	4	q22	NCBI

Aass
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955479	3,742,757 - 3,814,338 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955479	3,746,003 - 3,805,835 (-)	NCBI	ChiLan1.0	ChiLan1.0

AASS
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	6	158,945,704 - 159,016,545 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	7	10,955,958 - 11,026,799 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	7	114,084,792 - 114,155,558 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	7	126,769,655 - 126,840,346 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	7	126,769,655 - 126,840,346 (-)	Ensembl	panpan1.1		panPan2

AASS
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	14	59,950,123 - 59,993,457 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	14	59,951,216 - 60,000,212 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	14	59,366,730 - 59,419,159 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	14	59,984,503 - 60,037,014 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	14	59,986,237 - 60,035,749 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	14	60,076,161 - 60,128,175 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	14	59,703,783 - 59,756,172 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	14	60,081,118 - 60,133,517 (-)	NCBI		UU_Cfam_GSD_1.0

Aass
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	49,012,960 - 49,067,984 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936605	3,136,018 - 3,190,948 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936605	3,135,977 - 3,190,956 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

AASS
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	18	24,974,754 - 25,039,195 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	18	24,938,366 - 25,039,197 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	18	26,579,353 - 26,641,402 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Aass
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624783	13,831,150 - 13,902,082 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624783	13,831,220 - 13,904,806 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	endocrine system	hemolymphoid system	nervous system
High
Medium	4		16
Low	32	18	44
Below cutoff		2

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_007982735	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007982736	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007982738	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007982739	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007982740	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCSAT00000008668 ⟹ ENSCSAP00000006813

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	21	90,892,023 - 90,959,343 (-)	Ensembl

RefSeq Acc Id:

XM_007982735 ⟹ XP_007980926

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	21	90,891,781 - 90,959,351 (-)	NCBI
Vero_WHO_p1.0	NW_023666042	12,584,431 - 12,655,125 (+)	NCBI

Sequence:

show sequence

CCTTCCCAATTTCTGCTAGGAATTCGGAGCCTCCCCTGCAGCGACTCAGAAGATCCGAGGCGGC
GGGGGACAAGTCGGCGCCCCAGAGCGGACGAGTCACCAGGTGTCAAGATGCTGCGAGTCCATAG
GACTGGACTGAGCAGGCTGGAGGTCAGCCTCTCCAAGGGTCTTCACCACAAAGCTGTGTTGGCC
GTCCGGAGGGAGGATGTGAATGCCTGGGAGAGAAGGGCCCCTCTAGCTCCCAAGCACATCAAAG
GCATCACCAATCTGGGATACAAGGTCTTGATACAGCCTTCGAATCGACGGGCCATTCATGATAA
GGACTATGTCAAAGCTGGTGGCATTCTTCAGGAGGATATTTCTGAAGCTTGTCTAATTTTGGGA
GTTAAAAGACCTCCAGAGGAAAAATTAATGTCCAGGAAGACTTACGCATTTTTCTCCCACACAA
TAAAAGCTCAGGAGGCCAATATGGGCTTGTTGGATGAGATTCTAAAACAGGAAATTCGCCTTAT
TGATTATGAGAAAATGGTGGATCATAGAGGAGTACGGGTAGTGGCATTTGGACAGTGGGCTGGT
GTGGCAGGGATGATCAACATTTTACATGGAATGGGTTTAAGGCTCCTTGCTTTGGGACATCACA
CACCTTTTATGCACATTGGCATGGCTCATAACTACAGGAATAGCAGTCAGGCTGTGCAAGCTGT
TCGTGATGCTGGCTATGAAATATCTTTGGGTTTGATGCCTAAGTCAATAGGGCCCTTAACATTT
GTGTTCACAGGAACTGGTAATGTTTCTAAGGGAGCCCAAGCAATCTTTAATGAGCTACCTTGTG
AATATGTGGAGCCCCATGAATTAAAAGAAGTTTCCCAAACTGGAGACCTCAGAAAAGTGTATGG
GACAGTGTTAAGTCGTCATCATCATCTTGTCAGGAAAACAGATGGTGTGTATGATCCTGCAGAG
TATGACAAACATCCTGAGCGCTACATAAGTCGTTTTAATACTGATATTGCACCTTATACAACTT
GCTTAATTAATGGAATCTACTGGGAACAAAACACTCCTCGCCTCCTAACCCGCCAAGATGCTCA
GAGTCTCCTGGCTCCAGGCAAGTTCTCAGCTGCTGGTGTGGAAGGCTGCCCTTCATTACCACAC
AAACTTGTGGCAATATGTGACATTTCCGCTGACACAGGAGGGTCTATAGAGTTTATGACTGAGT
GTACAACAATAGAGCGTCCCTTTTGCATGTATGATGCAGACCAGCATATTATTCATGACAGTGT
TGAAGGCTCAGGGATCCTGATGTGTTCCATTGACAATTTGCCAGCACAGCTCCCAATTGAAGCT
ACAGAATGCTTTGGAGACATGCTTTACCCTTATGTTGAAGAAATGATATTATCAGATGCAACAC
AGCCTCTTGAAAGTCAGAATTTTTCTCCTGTGGTGAGAGATGCAGTGATTACATCCAACGGTAC
ATTACCTGATAAATATAAATATATCCAGACACTCCGGGAGAGCAGGGAATGTGCTCAGTCACTT
TCAATGGGCACCAGAAAGGTTTTGGTTCTTGGATCTGGCTATGTATCTGAGCCTGTATTGGAAT
ATTTATCAAGAGATGGCAATATAGAAATAACAGTAGGCTCTGACATGAAGAATCAAATTGAACA
GTTAGGCAAGAAATATAATATTAATCCTGTTAGCATGGACATTTGTAAACAAGAAGAGAAGCTG
GGCTTCTTGGTGGCAAAACAGGATCTTGTCATCAGCTTGTTGCCTTATGTATTGCACCCTCTTG
TGGCCAAGGCCTGCATCACAAACAAAGTTAACATGGTCACTGCAAGCTACATCACACCAGCACT
AAAAGAACTGGAAAAAAGTGTGGAAGATGCTGGCATCACAATCATTGGTGAATTGGGATTGGAC
CCTGGTCTTGATCACATGTTAGCAATGGAAACAATAGATAAAGCCAAGGAAGTGGGAGCCACGA
TTGAATCATATATTTCCTACTGTGGTGGGCTTCCAGCCCCCGAACATTCGAACAATCCATTGAG
ATATAAATTTAGCTGGAGTCCGGTGGGAGTTTTGATGAACGTAATGCAGTCTGCCACCTATCTG
CTTGATGGAAAGGTTGTGAATGTTGCAGGGGGCATCTTCTTTCTTGATGCCGTTACGTCCATGG
ATTTTTTCCCAGGATTAAATTTGGAAGGCTATCCTAACAGAGACAGTACGAAATATGCTGAGAT
TTATGGCATTTCTTCTGCTCACACTTTGTTGCGGGGGACACTGAGATATAAGGGATATATGAAA
GCTTTGAATGGATTTGTAAAATTAGGTCTTATAAACAGAGAAGCACTTCCTGCCTTTAGACCTG
AGGCCAACTTTCTCACCTGGAAACAACTCCTCTGTGACCTAGTTGGGATTTCACCCTCCTCTGA
GCACGACGTGTTGAAGGAAGCTGTTCTTAAGAAACTAGGAGGAGACAATACCCAGTTGGAGGCT
GCTGAATGGTTGGGCTTACTTGGGGATGAAGAAGTCCCTCAGGCAGAGTCCATTGTGGATGCCC
TCTCCAAGCATTTGGTCATGAAGCTTTCCTATGGTCCTGAAGAAAAAGATATGATTGTGATGAG
AGACAGCTTTGGAATCAGACATCCGTCTGGACATTTAGAAAATAAAACGATTGATCTTGTGGCT
TATGGGGACATCAATGGCTTTTCAGCCATGGCTAAAACCGTGGGGTTACCCACCGCCATGGCAG
CCAAAATGTTGCTTGACGGTGAAATTGGAGCCAAAGGCCTAATGGGGCCCTTTTCAAAGGAGAT
CTATGGACCAATATTGGAGCGAATTAAAGCAGAAGGCATTATATATACTACACAGAGTACAATT
AAACCATAATTGGGAATTATATTTTGTTCTTTTCTTCCCAGGCAATACAGCTCTGAACGTGTGT
GATAAATGGGTTTGCTAATGTGCTGTTTTAAAGTATAAAGCATAATATGTTTTGGTTAACACAA
TGTAGTTTGTGAACTATAAATCTGTATTTTAATATGGAAATGTTTGGAACAGGAGATGTCAGCT
ACTAACAGAGAATTTTAATAATTCTATCCTGTATTTTATAAATATGTATGTGAAAGTGA

hide sequence

RefSeq Acc Id:

XM_007982738 ⟹ XP_007980929

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	21	90,891,781 - 90,959,346 (-)	NCBI
Vero_WHO_p1.0	NW_023666042	12,584,459 - 12,655,125 (+)	NCBI

Sequence:

show sequence

CCAATTTCTGCTAGGAATTCGGAGCCTCCCCTGCAGCGACTCAGAAGATCCGAGGCGGCGGGGG
ACAAGTCGGCGCCCCAGAGCGGACGAGATTTCTCAGGAGACCAGAACTGATCTGCCAGTCCTGC
CACCTTTTGTTGCTCTGCTCTTTACATTGCCCTTACAGTCACCAGGTGTCAAGATGCTGCGAGT
CCATAGGACTGGACTGAGCAGGCTGGAGGTCAGCCTCTCCAAGGGTCTTCACCACAAAGCTGTG
TTGGCCGTCCGGAGGGAGGATGTGAATGCCTGGGAGAGAAGGGCCCCTCTAGCTCCCAAGCACA
TCAAAGGCATCACCAATCTGGGATACAAGGTCTTGATACAGCCTTCGAATCGACGGGCCATTCA
TGATAAGGACTATGTCAAAGCTGGTGGCATTCTTCAGGAGGATATTTCTGAAGCTTGTCTAATT
TTGGGAGTTAAAAGACCTCCAGAGGAAAAATTAATGTCCAGGAAGACTTACGCATTTTTCTCCC
ACACAATAAAAGCTCAGGAGGCCAATATGGGCTTGTTGGATGAGATTCTAAAACAGGAAATTCG
CCTTATTGATTATGAGAAAATGGTGGATCATAGAGGAGTACGGGTAGTGGCATTTGGACAGTGG
GCTGGTGTGGCAGGGATGATCAACATTTTACATGGAATGGGTTTAAGGCTCCTTGCTTTGGGAC
ATCACACACCTTTTATGCACATTGGCATGGCTCATAACTACAGGAATAGCAGTCAGGCTGTGCA
AGCTGTTCGTGATGCTGGCTATGAAATATCTTTGGGTTTGATGCCTAAGTCAATAGGGCCCTTA
ACATTTGTGTTCACAGGAACTGGTAATGTTTCTAAGGGAGCCCAAGCAATCTTTAATGAGCTAC
CTTGTGAATATGTGGAGCCCCATGAATTAAAAGAAGTTTCCCAAACTGGAGACCTCAGAAAAGT
GTATGGGACAGTGTTAAGTCGTCATCATCATCTTGTCAGGAAAACAGATGGTGTGTATGATCCT
GCAGAGTATGACAAACATCCTGAGCGCTACATAAGTCGTTTTAATACTGATATTGCACCTTATA
CAACTTGCTTAATTAATGGAATCTACTGGGAACAAAACACTCCTCGCCTCCTAACCCGCCAAGA
TGCTCAGAGTCTCCTGGCTCCAGGCAAGTTCTCAGCTGCTGGTGTGGAAGGCTGCCCTTCATTA
CCACACAAACTTGTGGCAATATGTGACATTTCCGCTGACACAGGAGGGTCTATAGAGTTTATGA
CTGAGTGTACAACAATAGAGCGTCCCTTTTGCATGTATGATGCAGACCAGCATATTATTCATGA
CAGTGTTGAAGGCTCAGGGATCCTGATGTGTTCCATTGACAATTTGCCAGCACAGCTCCCAATT
GAAGCTACAGAATGCTTTGGAGACATGCTTTACCCTTATGTTGAAGAAATGATATTATCAGATG
CAACACAGCCTCTTGAAAGTCAGAATTTTTCTCCTGTGGTGAGAGATGCAGTGATTACATCCAA
CGGTACATTACCTGATAAATATAAATATATCCAGACACTCCGGGAGAGCAGGGAATGTGCTCAG
TCACTTTCAATGGGCACCAGAAAGGTTTTGGTTCTTGGATCTGGCTATGTATCTGAGCCTGTAT
TGGAATATTTATCAAGAGATGGCAATATAGAAATAACAGTAGGCTCTGACATGAAGAATCAAAT
TGAACAGTTAGGCAAGAAATATAATATTAATCCTGTTAGCATGGACATTTGTAAACAAGAAGAG
AAGCTGGGCTTCTTGGTGGCAAAACAGGATCTTGTCATCAGCTTGTTGCCTTATGTATTGCACC
CTCTTGTGGCCAAGGCCTGCATCACAAACAAAGTTAACATGGTCACTGCAAGCTACATCACACC
AGCACTAAAAGAACTGGAAAAAAGTGTGGAAGATGCTGGCATCACAATCATTGGTGAATTGGGA
TTGGACCCTGGTCTTGATCACATGTTAGCAATGGAAACAATAGATAAAGCCAAGGAAGTGGGAG
CCACGATTGAATCATATATTTCCTACTGTGGTGGGCTTCCAGCCCCCGAACATTCGAACAATCC
ATTGAGATATAAATTTAGCTGGAGTCCGGTGGGAGTTTTGATGAACGTAATGCAGTCTGCCACC
TATCTGCTTGATGGAAAGGTTGTGAATGTTGCAGGGGGCATCTTCTTTCTTGATGCCGTTACGT
CCATGGATTTTTTCCCAGGATTAAATTTGGAAGGCTATCCTAACAGAGACAGTACGAAATATGC
TGAGATTTATGGCATTTCTTCTGCTCACACTTTGTTGCGGGGGACACTGAGATATAAGGGATAT
ATGAAAGCTTTGAATGGATTTGTAAAATTAGGTCTTATAAACAGAGAAGCACTTCCTGCCTTTA
GACCTGAGGCCAACTTTCTCACCTGGAAACAACTCCTCTGTGACCTAGTTGGGATTTCACCCTC
CTCTGAGCACGACGTGTTGAAGGAAGCTGTTCTTAAGAAACTAGGAGGAGACAATACCCAGTTG
GAGGCTGCTGAATGGTTGGGCTTACTTGGGGATGAAGAAGTCCCTCAGGCAGAGTCCATTGTGG
ATGCCCTCTCCAAGCATTTGGTCATGAAGCTTTCCTATGGTCCTGAAGAAAAAGATATGATTGT
GATGAGAGACAGCTTTGGAATCAGACATCCGTCTGGACATTTAGAAAATAAAACGATTGATCTT
GTGGCTTATGGGGACATCAATGGCTTTTCAGCCATGGCTAAAACCGTGGGGTTACCCACCGCCA
TGGCAGCCAAAATGTTGCTTGACGGTGAAATTGGAGCCAAAGGCCTAATGGGGCCCTTTTCAAA
GGAGATCTATGGACCAATATTGGAGCGAATTAAAGCAGAAGGCATTATATATACTACACAGAGT
ACAATTAAACCATAATTGGGAATTATATTTTGTTCTTTTCTTCCCAGGCAATACAGCTCTGAAC
GTGTGTGATAAATGGGTTTGCTAATGTGCTGTTTTAAAGTATAAAGCATAATATGTTTTGGTTA
ACACAATGTAGTTTGTGAACTATAAATCTGTATTTTAATATGGAAATGTTTGGAACAGGAGATG
TCAGCTACTAACAGAGAATTTTAATAATTCTATCCTGTATTTTATAAATATGTATGTGAAAGTG
A

hide sequence

Protein Sequences


Protein RefSeqs	XP_007980926	(Get FASTA)	NCBI Sequence Viewer
	XP_007980929	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000006813.1

RefSeq Acc Id:	XP_007980926 ⟸ XM_007982735
- UniProtKB:	A0A0D9RDX4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_007980929 ⟸ XM_007982738
- UniProtKB:	A0A0D9RDX4 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCSAP00000006813 ⟸ ENSCSAT00000008668

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000010587	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000008668.1	UniProtKB/TrEMBL
Gene3D-CATH	Domain 3, Saccharopine reductase	UniProtKB/TrEMBL
	NAD(P)-binding Rossmann-like Domain	UniProtKB/TrEMBL
InterPro	AlaDH/PNT_N	UniProtKB/TrEMBL
	AlaDH/PNT_NAD(H)-bd	UniProtKB/TrEMBL
	NAD(P)-bd_dom_sf	UniProtKB/TrEMBL
	Sacchrp_dh_C	UniProtKB/TrEMBL
	Sacchrp_dh_NADP	UniProtKB/TrEMBL
KEGG Report	csab:103226802	UniProtKB/TrEMBL
NCBI Gene	AASS	ENTREZGENE
PANTHER	ALPHA-AMINOADIPIC SEMIALDEHYDE SYNTHASE, MITOCHONDRIAL	UniProtKB/TrEMBL
	SACCHAROPINE DEHYDROGENASE	UniProtKB/TrEMBL
Pfam	AlaDh_PNT_N	UniProtKB/TrEMBL
	Sacchrp_dh_C	UniProtKB/TrEMBL
	Sacchrp_dh_NADP	UniProtKB/TrEMBL
SMART	AlaDh_PNT_C	UniProtKB/TrEMBL
	AlaDh_PNT_N	UniProtKB/TrEMBL
Superfamily-SCOP	Formate/glycerate dehydrogenase catalytic domain-like	UniProtKB/TrEMBL
	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	UniProtKB/TrEMBL
	SSF51735	UniProtKB/TrEMBL
UniProt	A0A0D9RDX4	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB