RGS12 (regulator of G protein signaling 12) - Rat Genome Database

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Gene: RGS12 (regulator of G protein signaling 12) Chlorocebus sabaeus
Analyze
Symbol: RGS12
Name: regulator of G protein signaling 12
RGD ID: 18642217
Description: ENCODES a protein that exhibits G-protein alpha-subunit binding (ortholog); GTPase activator activity (ortholog); GTPase regulator activity (ortholog); INVOLVED IN negative regulation of G protein-coupled receptor signaling pathway (ortholog); termination of G protein-coupled receptor signaling pathway (ortholog); PARTICIPATES IN calcium signaling pathway via the calcium-sensing receptor; G protein mediated signaling pathway via Galpha12/Galpha13 family; ASSOCIATED WITH cherubism (ortholog); Ellis-Van Creveld syndrome (ortholog); schizophrenia (ortholog); FOUND IN apical dendrite (ortholog); cytoplasm (ortholog); cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC103246446; LOC103246533; regulator of G-protein signaling 12; regulator of G-protein signaling 12-like
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12745,302,193 - 45,444,012 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660511,647,849 - 1,802,824 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
RGS12
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12745,302,193 - 45,444,012 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660511,647,849 - 1,802,824 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
RGS12
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3843,285,891 - 3,439,913 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl43,293,021 - 3,439,913 (+)EnsemblGRCh38hg38GRCh38
GRCh3743,287,618 - 3,441,640 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3643,285,672 - 3,411,438 (+)NCBINCBI36Build 36hg18NCBI36
Build 3443,425,087 - 3,478,607NCBI
Celera43,227,025 - 3,352,526 (+)NCBICelera
Cytogenetic Map4p16.3NCBI
HuRef43,253,766 - 3,378,780 (+)NCBIHuRef
CHM1_143,313,437 - 3,439,350 (+)NCBICHM1_1
T2T-CHM13v2.043,284,640 - 3,439,697 (+)NCBIT2T-CHM13v2.0
Rgs12
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39535,106,273 - 35,196,988 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl535,106,789 - 35,196,988 (+)EnsemblGRCm39 Ensembl
GRCm38534,948,929 - 35,039,642 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl534,949,445 - 35,039,644 (+)EnsemblGRCm38mm10GRCm38
MGSCv37535,292,097 - 35,376,244 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36535,266,308 - 35,350,456 (+)NCBIMGSCv36mm8
Celera532,423,269 - 32,508,385 (+)NCBICelera
Cytogenetic Map5B2NCBI
cM Map517.96NCBI
Rgs12
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81479,940,561 - 80,048,637 (-)NCBIGRCr8
mRatBN7.21475,715,925 - 75,824,012 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1475,715,934 - 75,794,596 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1480,175,876 - 80,263,170 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01481,416,503 - 81,503,793 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01477,861,725 - 77,949,017 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01480,975,239 - 81,069,519 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1480,975,322 - 81,053,906 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01481,664,122 - 81,771,788 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41481,363,542 - 81,436,194 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11481,365,932 - 81,438,585 (-)NCBI
Celera1474,648,755 - 74,720,676 (-)NCBICelera
Cytogenetic Map14q21NCBI
Rgs12
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555142,088,354 - 2,154,191 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555142,081,575 - 2,154,414 (+)NCBIChiLan1.0ChiLan1.0
RGS12
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v233,632,834 - 3,783,631 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan143,566,200 - 3,717,305 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v043,439,030 - 3,589,026 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.143,444,467 - 3,573,941 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl43,444,570 - 3,573,712 (+)Ensemblpanpan1.1panPan2
RGS12
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1360,917,033 - 61,011,812 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl360,917,072 - 61,009,131 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha363,567,210 - 63,619,308 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0361,392,603 - 61,512,294 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl361,392,635 - 61,512,321 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1360,884,355 - 61,003,999 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0361,090,461 - 61,208,240 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0361,446,826 - 61,566,535 (-)NCBIUU_Cfam_GSD_1.0
Rgs12
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528566,544,669 - 66,706,669 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647720,257,965 - 20,278,434 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0 EnsemblNW_00493647720,300,521 - 20,388,221 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647720,300,528 - 20,388,212 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RGS12
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl81,963,308 - 2,075,971 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.181,971,390 - 2,074,970 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.281,649,955 - 1,729,384 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Rgs12
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475524,489,966 - 24,553,505 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475524,489,746 - 24,567,937 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_037983143   ⟹   XP_037839071
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660511,647,849 - 1,802,824 (-)NCBI
RefSeq Acc Id: XM_037983144   ⟹   XP_037839072
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660511,647,849 - 1,802,788 (-)NCBI
RefSeq Acc Id: XM_037983145   ⟹   XP_037839073
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660511,647,849 - 1,802,824 (-)NCBI
RefSeq Acc Id: XM_037983146   ⟹   XP_037839074
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660511,656,666 - 1,802,824 (-)NCBI
RefSeq Acc Id: XM_037983147   ⟹   XP_037839075
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660511,647,849 - 1,687,315 (-)NCBI
RefSeq Acc Id: XM_037983148   ⟹   XP_037839076
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660511,647,849 - 1,726,257 (-)NCBI
RefSeq Acc Id: XM_037983149   ⟹   XP_037839077
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660511,647,849 - 1,802,807 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_037839073   ⟸   XM_037983145
- Peptide Label: isoform X2
RefSeq Acc Id: XP_037839071   ⟸   XM_037983143
- Peptide Label: isoform X1
RefSeq Acc Id: XP_037839077   ⟸   XM_037983149
- Peptide Label: isoform X6
RefSeq Acc Id: XP_037839072   ⟸   XM_037983144
- Peptide Label: isoform X1
RefSeq Acc Id: XP_037839076   ⟸   XM_037983148
- Peptide Label: isoform X5
RefSeq Acc Id: XP_037839075   ⟸   XM_037983147
- Peptide Label: isoform X4
RefSeq Acc Id: XP_037839074   ⟸   XM_037983146
- Peptide Label: isoform X3


Additional Information

Database Acc Id Source(s)
NCBI Gene LOC103246446 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-12-08 RGS12  regulator of G protein signaling 12  LOC103246446  regulator of G-protein signaling 12  Symbol and/or name change 5135510 APPROVED
2020-12-03 LOC103246446  regulator of G-protein signaling 12  LOC103246533  regulator of G-protein signaling 12-like  Data merged from RGD:18566832 737654 PROVISIONAL