BAG1 (BAG cochaperone 1) - Rat Genome Database

Name: BAG1
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: BAG1 (BAG cochaperone 1) Chlorocebus sabaeus

Analyze

Symbol:

BAG1

Name:

BAG cochaperone 1

RGD ID:

18619069

Description:

ENCODES a protein that exhibits adenyl-nucleotide exchange factor activity (ortholog); ubiquitin protein ligase binding (ortholog); INVOLVED IN apoptotic process (ortholog); chaperone cofactor-dependent protein refolding (ortholog); negative regulation of apoptotic process (ortholog); PARTICIPATES IN chaperone mediated autophagy pathway; ASSOCIATED WITH acromesomelic dysplasia, Maroteaux type (ortholog); breast cancer (ortholog); Breast Neoplasms (ortholog); FOUND IN cytosol (ortholog); nucleoplasm (ortholog); nucleus (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

BAG family molecular chaperone regulator 1; BCL2 associated athanogene 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	BAG1 (BAG cochaperone 1)	NCBI	Ortholog
Mus musculus (house mouse):	Bag1 (BCL2-associated athanogene 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Bag1 (BAG cochaperone 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Bag1 (BAG cochaperone 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	BAG1 (BAG cochaperone 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	BAG1 (BAG cochaperone 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Bag1 (BAG cochaperone 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	BAG1 (BAG cochaperone 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Bag1 (BAG cochaperone 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	47,006,177 - 47,016,177 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666038	43,900,059 - 43,910,137 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

acromesomelic dysplasia, Maroteaux type (ISO)

breast cancer (ISO)

Breast Neoplasms (ISO)

cervix carcinoma (ISO)

COVID-19 (ISO)

distal arthrogryposis type 1A (ISO)

endometrial cancer (ISO)

frontotemporal dementia and/or amyotrophic lateral sclerosis 6 (ISO)

galactosemia (ISO)

Huntington's disease (ISO)

invasive ductal carcinoma (ISO)

lesion of sciatic nerve (ISO)

Lymphatic Metastasis (ISO)

primary ciliary dyskinesia (ISO)

prostate cancer (ISO)

Reperfusion Injury (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

apoptotic process (ISO)

chaperone cofactor-dependent protein refolding (ISO)

negative regulation of apoptotic process (ISO)

negative regulation of motor neuron apoptotic process (ISO)

negative regulation of protein phosphorylation (ISO)

neuron differentiation (ISO)

positive regulation of Schwann cell differentiation (ISO)

positive regulation of smooth muscle cell apoptotic process (ISO)

protein localization to mitochondrion (ISO)

response to benzene (ISO)

response to nicotine (ISO)

response to organic cyclic compound (ISO)

response to xenobiotic stimulus (ISO)

Cellular Component

cytosol (ISO)

nucleoplasm (ISO)

nucleus (ISO)

perinuclear region of cytoplasm (ISO)

Molecular Function

adenyl-nucleotide exchange factor activity (ISO)

protein binding (ISO)

ubiquitin protein ligase binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

chaperone mediated autophagy pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

BAG1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	47,006,177 - 47,016,177 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666038	43,900,059 - 43,910,137 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

BAG1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	33,252,471 - 33,264,708 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	9	33,247,820 - 33,264,720 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	9	33,252,469 - 33,264,706 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	33,242,469 - 33,254,761 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	9	33,245,025 - 33,254,737	NCBI
Celera	9	33,182,605 - 33,194,897 (-)	NCBI		Celera
Cytogenetic Map	9	p13.3	NCBI
HuRef	9	33,209,370 - 33,221,664 (-)	NCBI		HuRef
CHM1_1	9	33,251,269 - 33,264,545 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	9	33,271,122 - 33,283,355 (-)	NCBI		T2T-CHM13v2.0

Bag1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	40,936,398 - 40,948,294 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	40,936,398 - 40,948,294 (-)	Ensembl		GRCm39 Ensembl
GRCm38	4	40,936,398 - 40,948,294 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	40,936,398 - 40,948,294 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	40,883,431 - 40,895,327 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	41,125,088 - 41,136,908 (-)	NCBI		MGSCv36	mm8
Celera	4	40,597,072 - 40,608,972 (-)	NCBI		Celera
Cytogenetic Map	4	A5	NCBI
cM Map	4	20.67	NCBI

Bag1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	60,864,476 - 60,877,059 (-)	NCBI		GRCr8
mRatBN7.2	5	56,068,494 - 56,081,075 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	56,068,494 - 56,081,075 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	58,035,035 - 58,047,611 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	59,854,186 - 59,866,762 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	59,848,377 - 59,861,135 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	57,254,421 - 57,267,002 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	57,254,421 - 57,267,002 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	61,785,751 - 61,798,332 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	58,329,720 - 58,342,293 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	58,329,898 - 58,342,460 (-)	NCBI
Celera	5	54,680,341 - 54,692,922 (-)	NCBI		Celera
Cytogenetic Map	5	q22	NCBI

Bag1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955472	2,394,317 - 2,405,199 (+)	NCBI	ChiLan1.0	ChiLan1.0

BAG1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	11	91,339,036 - 91,348,601 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	9	91,345,096 - 91,354,543 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	9	33,033,267 - 33,043,013 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	9	33,841,254 - 33,851,242 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	33,841,449 - 33,851,167 (-)	Ensembl	panpan1.1		panPan2

BAG1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	11	50,348,833 - 50,363,532 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	11	50,350,999 - 50,363,581 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	11	48,978,818 - 48,993,481 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	11	51,288,922 - 51,303,809 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	11	51,288,044 - 51,303,858 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	11	49,953,304 - 49,967,917 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	11	49,820,251 - 49,835,112 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	11	50,585,344 - 50,600,226 (-)	NCBI		UU_Cfam_GSD_1.0

Bag1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	165,245,421 - 165,256,566 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936524	1,791,119 - 1,804,151 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936524	1,793,001 - 1,804,145 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

BAG1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	10	33,227,338 - 33,240,724 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	10	33,227,530 - 33,240,731 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	10	37,484,543 - 37,497,844 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Bag1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624736	38,015,044 - 38,025,079 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624736	38,015,150 - 38,025,079 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_007969002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

XM_007969002 ⟹ XP_007967193

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	12	47,006,177 - 47,016,177 (+)	NCBI
Vero_WHO_p1.0	NW_023666038	43,900,059 - 43,910,137 (+)	NCBI

Sequence:

show sequence

AAGCAGTCGGGCGGGGTTGTAAGACGCCGCGCTCAGCTACCATCGCTGGGCGGTCAACAAGCGC
GGGCCTGGCTCAACGCGGCGGGGCGCGGAGACCACGAGGCGACCGGGAGCGGCTGGGCTCTCGG
CTGCGCGCCCTTCGGCCAGGCCGTGAGCCGCGCCAGTCGGAGCCCCCGGCCCAGCGTGGCCCGC
CTCCCTCTCGGCGTCCACCTGTCTGGGGTGCTGCCAGCGGGCATGACCGACCCACCAGGGGCGC
CGCCTCCGGCGCTCGCAGGCCGCGGATGAAGAAGAAGACCCGGCGCCGCTCGACCCGGAGCGAG
GAGTTGACCCTGAGTGAGGAGGCGACCCGGAGCGAAGAGGCGACCCAGAGTGAGGAGGCGACTC
GGGGCGAAGAGATGAATCGGAGCCAGGAGGTGACCCGGGACGAGGAGGCGACCCAGAGCGAGGA
GGTGACCAGGGAGGAAATGGCGGCAGCTGGGCTCACCGTGACTGTCACCCACAGCAATGAGAAG
CACGACCTTCATGTTACCCCACAGCAGGGCAGCAGTGAACCAGTTGTCCAAGACCTGGCCCAGG
TTGTTGAAGAGGCCATAGGGGTTCCACAGTCTTTTCAGAAACTCATATTTAAGGGAAAATCCCT
GAAGGAAATGGAAACACCATTGTCAGCACTTGGAATACAAGATGGTTGCCGGGTCATGTTAATT
GGGAAAAAGAACAGTCCAGAGGAAGAGGTTGAACTAAAGAAGTTGAAACATTTGGAGAAGTCTG
TGGAGAAGATAGCTGACCAGCTGGAAGAGTTGAATAAAGAACTTACTGGAATACAGCAGGGTTT
TCTGCCCAAGGATTTGCAAGCTGAAGCTCTCTGCAAACTTGATAGGAGAGTAAAAGCCACAATA
GAGCAGTTTATGAAGATCTTGGAGGAGATTGACACACTGATCCTGCCAGAAAATTTCAAAGACA
GTAGATTGAAAAGGAAAGGCTTGGTAAAAAAGGTTCAGGCATTCCTAGCTGAGTGTGACGCAGT
GGAGCAGAACATCTGCCAGGAGACAGAGCGACTGCAGTCTACAAACTTTGCCCTGGCCGAGTGA
GGTGTGGCAGAAAGAGGCTGTGCTGCCCTGAAGAATGGCACCAGCAGCTCTGCCGTCTCTGGAG
CAGAATTTACCTGATTTCTTCAGGGCTGCTAGGGGCAACTGGCCATTTGCCAGTTTTCCTACTC
TCACCCGGTTCTCAATGAAAAACAGTGTCTTTGTGATTTTGAGTAAAGCTCCTGTCTGTTTTCT
CCTT

hide sequence

Protein Sequences


Protein RefSeqs	XP_007967193	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_007967193 ⟸ XM_007969002

Additional Information

External Database Links

Database	Acc Id	Source(s)
NCBI Gene	BAG1	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations