KIF3C (kinesin family member 3C) - Rat Genome Database

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Gene: KIF3C (kinesin family member 3C) Chlorocebus sabaeus
Analyze
Symbol: KIF3C
Name: kinesin family member 3C
RGD ID: 18607494
Description: ENCODES a protein that exhibits kinesin binding (ortholog); microtubule binding (ortholog); INVOLVED IN positive regulation of neuron projection development (ortholog); ASSOCIATED WITH amyotrophic lateral sclerosis type 1 (ortholog); atrial fibrillation (ortholog); Tatton-Brown-Rahman syndrome (ortholog); FOUND IN axon (ortholog); dendrite (ortholog); growth cone (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: kinesin-like protein KIF3C
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11481,666,884 - 81,717,489 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1481,666,793 - 81,717,508 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604530,438,707 - 30,491,806 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
KIF3C
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11481,666,884 - 81,717,489 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1481,666,793 - 81,717,508 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604530,438,707 - 30,491,806 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
KIF3C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38225,926,598 - 25,982,497 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl225,926,598 - 25,982,749 (-)EnsemblGRCh38hg38GRCh38
GRCh37226,149,467 - 26,205,366 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36226,002,959 - 26,058,947 (-)NCBINCBI36Build 36hg18NCBI36
Build 34226,061,118 - 26,117,054NCBI
Celera225,989,739 - 26,045,730 (-)NCBICelera
Cytogenetic Map2p23.3NCBI
HuRef225,886,207 - 25,942,013 (-)NCBIHuRef
CHM1_1226,079,044 - 26,135,487 (-)NCBICHM1_1
T2T-CHM13v2.0225,961,945 - 26,017,861 (-)NCBIT2T-CHM13v2.0
Kif3c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39123,415,132 - 3,456,494 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl123,415,132 - 3,456,494 (+)EnsemblGRCm39 Ensembl
GRCm38123,365,132 - 3,406,494 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl123,365,132 - 3,406,494 (+)EnsemblGRCm38mm10GRCm38
MGSCv37123,365,132 - 3,406,494 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36123,365,132 - 3,406,494 (+)NCBIMGSCv36mm8
Celera123,292,187 - 3,333,551 (+)NCBICelera
Cytogenetic Map12A1.1NCBI
cM Map121.77NCBI
Kif3c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8632,086,879 - 32,125,812 (+)NCBIGRCr8
mRatBN7.2626,367,092 - 26,406,033 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl626,366,531 - 26,406,130 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx626,659,683 - 26,698,621 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0626,975,571 - 27,014,501 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0626,453,926 - 26,492,858 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0627,768,943 - 27,815,611 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl627,768,943 - 27,815,611 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0637,579,445 - 37,625,883 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4626,342,388 - 26,381,233 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1626,345,340 - 26,384,186 (+)NCBI
Celera625,843,783 - 25,882,712 (+)NCBICelera
Cytogenetic Map6q14NCBI
Kif3c
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554697,958,481 - 8,001,738 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554697,960,224 - 8,001,161 (-)NCBIChiLan1.0ChiLan1.0
KIF3C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v212100,536,872 - 100,591,788 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A100,540,100 - 100,595,754 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A25,927,039 - 25,982,715 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A26,020,025 - 26,074,961 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A26,020,025 - 26,074,961 (-)Ensemblpanpan1.1panPan2
KIF3C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11720,090,374 - 20,128,703 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1720,091,759 - 20,128,562 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1719,986,149 - 20,024,501 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01720,411,768 - 20,450,554 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1720,411,774 - 20,451,095 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11720,098,664 - 20,136,938 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01720,109,348 - 20,147,627 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01720,155,378 - 20,193,906 (-)NCBIUU_Cfam_GSD_1.0
Kif3c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629264,402,587 - 64,442,970 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364936,396,276 - 6,435,266 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364936,396,606 - 6,435,266 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KIF3C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3112,966,804 - 113,014,624 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13112,963,424 - 113,014,632 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23119,943,241 - 119,968,158 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Kif3c
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247388,127,797 - 8,171,697 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247388,128,594 - 8,171,638 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 20 60
Low 16 18
Below cutoff 2

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_007971255 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCSAT00000006749   ⟹   ENSCSAP00000004945
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1481,666,793 - 81,717,508 (+)Ensembl
RefSeq Acc Id: XM_007971255   ⟹   XP_007969446
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11481,666,884 - 81,717,489 (+)NCBI
Vero_WHO_p1.0NW_02366604530,438,707 - 30,491,806 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007969446 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000004945
  ENSCSAP00000004945.1
Reference Protein Sequences
RefSeq Acc Id: XP_007969446   ⟸   XM_007971255
- UniProtKB: A0A0D9R8K6 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000004945   ⟸   ENSCSAT00000006749


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000008688 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000006749.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.850.10 UniProtKB/TrEMBL
InterPro Kinesin-like_fam UniProtKB/TrEMBL
  Kinesin_motor_CS UniProtKB/TrEMBL
  Kinesin_motor_dom UniProtKB/TrEMBL
  Kinesin_motor_dom_sf UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
KEGG Report csab:103220646 UniProtKB/TrEMBL
NCBI Gene KIF3C ENTREZGENE
PANTHER CENTROMERE PROTEIN E UniProtKB/TrEMBL
  KINESIN-LIKE PROTEIN UniProtKB/TrEMBL
Pfam Kinesin UniProtKB/TrEMBL
PRINTS KINESINHEAVY UniProtKB/TrEMBL
PROSITE KINESIN_MOTOR_1 UniProtKB/TrEMBL
  KINESIN_MOTOR_2 UniProtKB/TrEMBL
SMART KISc UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A0D9R8K6 ENTREZGENE, UniProtKB/TrEMBL