Gml (glycosylphosphatidylinositol anchored molecule like) - Rat Genome Database

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Gene: Gml (glycosylphosphatidylinositol anchored molecule like) Mus musculus
Analyze
Symbol: Gml
Name: glycosylphosphatidylinositol anchored molecule like
RGD ID: 1621804
MGI Page MGI
Description: Orthologous to human GML (glycosylphosphatidylinositol anchored molecule like).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: EG625599; hematopoietic cell transcript 3; HemT; hemT-3 protein
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391574,685,283 - 74,691,898 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1574,685,301 - 74,690,664 (-)EnsemblGRCm39 Ensembl
GRCm381574,813,434 - 74,820,049 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1574,813,452 - 74,818,815 (-)EnsemblGRCm38mm10GRCm38
MGSCv371574,643,884 - 74,649,245 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361574,640,709 - 74,645,982 (-)NCBIMGSCv36mm8
Celera1576,320,413 - 76,324,166 (-)NCBICelera
Cytogenetic Map15D3NCBI
cM Map1534.28NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10231568   PMID:12477932   PMID:16141072   PMID:27098205  


Genomics

Comparative Map Data
Gml
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391574,685,283 - 74,691,898 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1574,685,301 - 74,690,664 (-)EnsemblGRCm39 Ensembl
GRCm381574,813,434 - 74,820,049 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1574,813,452 - 74,818,815 (-)EnsemblGRCm38mm10GRCm38
MGSCv371574,643,884 - 74,649,245 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361574,640,709 - 74,645,982 (-)NCBIMGSCv36mm8
Celera1576,320,413 - 76,324,166 (-)NCBICelera
Cytogenetic Map15D3NCBI
cM Map1534.28NCBI
GML
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388142,834,801 - 142,846,851 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8142,834,247 - 142,916,506 (+)EnsemblGRCh38hg38GRCh38
GRCh378143,916,217 - 143,928,267 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 368143,913,219 - 143,925,264 (+)NCBINCBI36Build 36hg18NCBI36
Build 348143,913,218 - 143,925,264NCBI
Celera8140,225,950 - 140,237,983 (+)NCBICelera
Cytogenetic Map8q24.3NCBI
HuRef8139,168,331 - 139,180,326 (+)NCBIHuRef
CHM1_18143,956,347 - 143,968,421 (+)NCBICHM1_1
T2T-CHM13v2.08143,978,146 - 143,990,184 (+)NCBIT2T-CHM13v2.0
Gml
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87108,578,386 - 108,601,738 (-)NCBIGRCr8
mRatBN7.27106,683,749 - 106,712,802 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7106,689,410 - 106,712,724 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.07116,054,862 - 116,063,459 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7116,039,715 - 116,063,098 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07115,960,326 - 115,975,471 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47112,937,278 - 112,940,886 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17112,971,366 - 112,975,116 (+)NCBI
Celera7103,105,681 - 103,113,951 (-)NCBICelera
Cytogenetic Map7q34NCBI
Gml
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554541,724,859 - 1,735,424 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554541,724,929 - 1,735,380 (+)NCBIChiLan1.0ChiLan1.0
GML
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27160,271,607 - 160,290,017 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan18135,797,821 - 135,818,031 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08139,497,857 - 139,560,838 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18142,589,622 - 142,601,636 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8142,589,622 - 142,601,636 (+)Ensemblpanpan1.1panPan2
LOC100684332
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_Tasha1336,754,369 - 36,755,090 (-)NCBIDog10K_Boxer_Tasha
Gml
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244053031,550,244 - 1,571,521 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049364708,978,825 - 8,997,476 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GML
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.141,355,696 - 1,364,106 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
GML
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18137,070,864 - 137,095,154 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl8137,088,766 - 137,094,991 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660392,853,102 - 2,873,404 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gml
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473513,737,122 - 13,749,775 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Gml
197 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:233
Count of miRNA genes:110
Interacting mature miRNAs:113
Transcripts:ENSMUST00000096400, ENSMUST00000164026
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4141952W3q7_mweight 3 weeks QTL 7 (mouse)Not determined348969478601286Mouse
4142252Tailaq4_mtail length adjusted QTL 4 (mouse)Not determined348969478601286Mouse
4142448Tailq6_mtail length QTL 6 (mouse)Not determined348969478601286Mouse
1357559Scfq2_msubcutaneous fat pad weight QTL 2 (mouse)Not determined15348969478601286Mouse
1357659Epfpq4_mepididymal fat percentage QTL 4 (mouse)Not determined15348969478601286Mouse
27226786Feml11_mfemur length 11, 5 week (mouse)15612948175871849Mouse
27095932Ulnl11_mulna length 11, 16 week (mouse)15612948176384200Mouse
27226717Tibw4_mtibia width 4, proximal, 10 week (mouse)15612948178684200Mouse
27226734Tibmd5_mtibia midshaft diameter 5, 10 week (mouse)15612948186684201Mouse
26884442Sklq6_mskull length QTL 6, 5 week (mouse)156129481100797881Mouse
27226721Tibw8_mtibia width 8, proximal, 16 week (mouse)15692948175871849Mouse
27226773Tibl16_mtibia length 16, 10 week (mouse)15692948175871849Mouse
27226777Tibl8_mtibia length 8, 5 week (mouse)15692948184584201Mouse
1301433Rapop5_mradiation-induced apoptosis 5 (mouse)Not determined15927302279474762Mouse
1357526Hyplip2_mhyperlipidemia 2 (mouse)Not determined1512402203102896555Mouse
26884425Cvht2_mcranial vault height 2, 5 week (mouse)1528800146102008435Mouse
26884392Humsd8_mhumerus midshaft diameter 8, 16 week (mouse)152930014676084200Mouse
1558985Eae32_mexperimental allergic encephalomyelitis susceptibility 32 (mouse)Not determined1532578416103425899Mouse
27226729Tibmd2_mtibia midshaft diameter 2, 5 week (mouse)153800024486684201Mouse
26884402Cvht9_mcranial vault height 9, 16 week (mouse)154216339695497881Mouse
1357703Vtbt17_mvertebral trabecular bone trait 17 (mouse)Not determined154455331378553437Mouse
1301568Tria2_mT-cell receptor induced activation 2 (mouse)Not determined154485914178859281Mouse
1357756Alaa4_malopecia areata 4 (mouse)Not determined154638964680389845Mouse
10755515Amzn3_manatomical modifier of Zfp423 3 (mouse)154638964680389845Mouse
1301006Hfib1_mhepatic fibrogenesis 1 (mouse)Not determined154730633481306479Mouse
1301860Gct3_mgranulosa cell tumorigenesis 3 (mouse)Not determined154740959681409691Mouse
26884397Humsd5_mhumerus midshaft diameter 5, 10 week (mouse)154836339698397881Mouse
26884399Humsd1_mhumerus midshaft diameter 1, 5 week (mouse)1548363396101708435Mouse
1301429Pcir3_mperiosteal circumference 3 (mouse)Not determined154846536282465496Mouse
1301779Dpml_mdopamine loss (mouse)Not determined155100469476794493Mouse
4142198Hbtq_mhabituation QTL (mouse)Not determined155116070885160833Mouse
10045637Heal27_mwound healing/regeneration 29 (mouse)Not determined155141836185418511Mouse
10412067Pain2_mpain 2 (mouse)Not determined155164533985645626Mouse
1302080Szs13_mseizure susceptibility 13 (mouse)Not determined155168583285694449Mouse
1301708Cocrb14_mcocaine related behavior 14 (mouse)Not determined155180651585806651Mouse
38501067Tip3_mtuberculosis immunophenotype 3, IFN-g level (mouse)155356339689584203Mouse
13504731Cath5_mcarotid atherosclerosis 5 (mouse)155478912988789129Mouse
1302074Bmd4_mbone mineral density 4 (mouse)Not determined1556186708103425899Mouse
27095936Ulnl4_mulna length 4, 5 week (mouse)155676339687684201Mouse
1300800Ses3_msalmonella enteritidis susceptibility 3 (mouse)Not determined155711700591117153Mouse
1357407Pfat4_mpredicted fat percentage 4 (mouse)8.6Body fat amountpredicted fat percentage155711700591117153Mouse
12880420V25Dq8_mvitamin D inactive form serum level QTL 8 (mouse)156158420095584200Mouse
1301601Faq9_mfluctuating asymmetry QTL 9 (mouse)Not determined156316390397163995Mouse
1558786Msq1_mMAV-1 susceptibility QTL 1 (mouse)Not determined156338964681086436Mouse
1302197Bhr2_mbronchial hyperresponsiveness 2 (mouse)Not determined1564306334103425899Mouse
4141135Cia35_mcollagen induced arthritis 35 (mouse)Not determined156481182698811946Mouse
1301119Drb7_mdopamine receptor binding 7 (mouse)Not determined156533657899341028Mouse
1301171Brm2_mbrachyury modifier 2 (mouse)Not determined156552537699525499Mouse
4141921Pstc3_mperiosteal circumference 3 (mouse)Not determined1567270698101270847Mouse
1300627Sluc26_msusceptibility to lung cancer 26 (mouse)Not determined1570345653104073951Mouse
1300648Dbsty4_mdiabesity 4 (mouse)Not determined1570349271104073951Mouse
1300726Pitm4_mprion incubation time 4 (mouse)Not determined1570349271104073951Mouse
25671381Hrsq3_mhost response to SARS QTL 3, eosinophilia (mouse)157214453975844833Mouse
1300844Emo2_memotionality 2 (mouse)Not determined157237245976794493Mouse
1302002Cocia2_mcocaine induced activation 2 (mouse)Not determined157237245979899178Mouse
14747011Mancz13_mmandible centroid size 13 (mouse)1572382669104073951Mouse
12791003Aath8_maortic arch atherosclerosis 8 (mouse)1573430144104073951Mouse
15092079Igly6_mIgG glycosylation 6, GP6 (mouse)157410054082674156Mouse
13442492Mecth2_mmechanosensation threshold 2 (mouse)157466284979387201Mouse

Markers in Region
UniSTS:492583  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381574,823,072 - 74,824,399UniSTSGRCm38
GRCm381574,813,494 - 74,814,686UniSTSGRCm38
MGSCv371574,653,502 - 74,654,829UniSTSGRCm37
MGSCv371574,643,924 - 74,645,116UniSTSGRCm37
Celera1576,320,453 - 76,321,645UniSTS
Celera1576,329,289 - 76,330,616UniSTS
Cytogenetic Map15D3UniSTS


Expression


Sequence


RefSeq Acc Id: ENSMUST00000096400   ⟹   ENSMUSP00000094131
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1574,685,301 - 74,689,322 (-)Ensembl
GRCm38.p6 Ensembl1574,813,452 - 74,817,473 (-)Ensembl
RefSeq Acc Id: ENSMUST00000164026   ⟹   ENSMUSP00000128174
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1574,685,303 - 74,690,664 (-)Ensembl
GRCm38.p6 Ensembl1574,813,454 - 74,818,815 (-)Ensembl
RefSeq Acc Id: ENSMUST00000185253   ⟹   ENSMUSP00000140245
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1574,685,661 - 74,690,662 (-)Ensembl
GRCm38.p6 Ensembl1574,813,812 - 74,818,813 (-)Ensembl
RefSeq Acc Id: NM_001177524   ⟹   NP_001170995
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391574,685,301 - 74,690,579 (-)NCBI
GRCm381574,813,454 - 74,818,815 (-)NCBI
MGSCv371574,643,884 - 74,649,245 (-)RGD
Celera1576,320,413 - 76,324,166 (-)RGD
cM Map15 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001415959   ⟹   NP_001402888
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391574,685,301 - 74,690,579 (-)NCBI
RefSeq Acc Id: NM_001415965   ⟹   NP_001402894
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391574,685,301 - 74,689,431 (-)NCBI
RefSeq Acc Id: XM_011245704   ⟹   XP_011244006
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391574,685,284 - 74,691,898 (-)NCBI
GRCm381574,813,435 - 74,820,049 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011245705   ⟹   XP_011244007
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391574,685,284 - 74,689,429 (-)NCBI
GRCm381574,813,435 - 74,817,580 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030248680   ⟹   XP_030104540
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391574,685,283 - 74,689,378 (-)NCBI
GRCm381574,813,434 - 74,817,529 (-)NCBI
Sequence:
RefSeq Acc Id: NP_001170995   ⟸   NM_001177524
- Peptide Label: isoform 1 precursor
- UniProtKB: E9PX31 (UniProtKB/TrEMBL),   Q9QUL5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011244006   ⟸   XM_011245704
- Peptide Label: isoform X3
- UniProtKB: E9PX31 (UniProtKB/TrEMBL),   Q9QUL5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011244007   ⟸   XM_011245705
- Peptide Label: isoform X3
- UniProtKB: E9PX31 (UniProtKB/TrEMBL),   Q9QUL5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030104540   ⟸   XM_030248680
- Peptide Label: isoform X1
RefSeq Acc Id: ENSMUSP00000128174   ⟸   ENSMUST00000164026
RefSeq Acc Id: ENSMUSP00000140245   ⟸   ENSMUST00000185253
RefSeq Acc Id: ENSMUSP00000094131   ⟸   ENSMUST00000096400
RefSeq Acc Id: NP_001402888   ⟸   NM_001415959
- Peptide Label: isoform 2 precursor
RefSeq Acc Id: NP_001402894   ⟸   NM_001415965
- Peptide Label: isoform 1 precursor
- UniProtKB: E9PX31 (UniProtKB/TrEMBL)
Protein Domains
UPAR/Ly6

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-E9PX31-F1-model_v2 AlphaFold E9PX31 1-176 view protein structure

Promoters
RGD ID:8683974
Promoter ID:EPDNEW_M20018
Type:initiation region
Name:Gml_1
Description:Mus musculus glycosylphosphatidylinositol anchored molecule like, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381574,818,730 - 74,818,790EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3644767 AgrOrtholog
Ensembl Genes ENSMUSG00000068349 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000096400 ENTREZGENE
  ENSMUST00000096400.10 UniProtKB/TrEMBL
  ENSMUST00000164026 ENTREZGENE
  ENSMUST00000164026.8 UniProtKB/TrEMBL
  ENSMUST00000185253.2 UniProtKB/TrEMBL
Gene3D-CATH 2.10.60.10 UniProtKB/TrEMBL
InterPro LY6_UPA_recep-like UniProtKB/TrEMBL
  Snake_toxin-like_sf UniProtKB/TrEMBL
KEGG Report mmu:625599 UniProtKB/TrEMBL
MGD MGI:3644767 ENTREZGENE
NCBI Gene 625599 ENTREZGENE
PANTHER GLYCOSYL-PHOSPHATIDYLINOSITOL-ANCHORED MOLECULE-LIKE PROTEIN UniProtKB/TrEMBL
  GLYCOSYL-PHOSPHATIDYLINOSITOL-ANCHORED MOLECULE-LIKE PROTEIN-RELATED UniProtKB/TrEMBL
Pfam UPAR_LY6 UniProtKB/TrEMBL
PhenoGen Gml PhenoGen
SMART SM00134 UniProtKB/TrEMBL
Superfamily-SCOP SSF57302 UniProtKB/TrEMBL
UniProt A0A087WQL5_MOUSE UniProtKB/TrEMBL
  E9PX31 ENTREZGENE, UniProtKB/TrEMBL
  Q9QUL5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-06-30 Gml  glycosylphosphatidylinositol anchored molecule like    GPI anchored molecule like protein  Symbol and/or name change 5135510 APPROVED