Or8a1 (olfactory receptor family 8 subfamily A member 1)

Gene: Or8a1 (olfactory receptor family 8 subfamily A member 1) Mus musculus

Analyze

No known orthologs.

Symbol:

Or8a1

Name:

olfactory receptor family 8 subfamily A member 1

RGD ID:

1619644

MGI Page

MGI

Description:

Predicted to enable odorant binding activity and olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and sensory perception of smell. Predicted to be located in membrane. Is expressed in olfactory epithelium. Orthologous to human OR8A1 (olfactory receptor family 8 subfamily A member 1).

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

GA_x6K02T2PVTD-31408136-31407207; M71; M71 odorant receptor; MOR171; MOR171-2; odorant receptor M71; olfactory receptor 151; olfactory receptor 171-2; olfactory receptor 7H; olfactory receptor 8A1; Olfr151

RGD Orthologs

Alliance Orthologs

More Info

homologs ...

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

NCBI Annotation Information:

Note: Genetic polymorphisms result in both protein coding and non-coding alleles of this gene.

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	37,641,273 - 37,642,357 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	37,641,273 - 37,642,400 (-)	Ensembl		GRCm39 Ensembl
GRCm38	9	37,729,977 - 37,731,061 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	37,729,977 - 37,731,104 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	37,537,562 - 37,538,646 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	37,479,724 - 37,480,652 (-)	NCBI		MGSCv36	mm8
Celera	9	34,948,013 - 34,949,098 (-)	NCBI		Celera
Cytogenetic Map	9	A4	NCBI
cM Map	9	20.8	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

G protein-coupled receptor signaling pathway (IBA,ISA)

sensory perception of smell (IBA,ISA)

Cellular Component

endoplasmic reticulum membrane (TAS)

membrane (ISA)

plasma membrane (TAS)

Molecular Function

odorant binding (IBA)

olfactory receptor activity (IBA,ISA)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

abnormal axon extension (IAGP)

abnormal innervation (IAGP)

abnormal neuron morphology (IAGP)

abnormal olfactory bulb development (IAGP)

abnormal olfactory bulb interneuron morphology (IAGP)

abnormal olfactory bulb morphology (IAGP)

abnormal olfactory neuron innervation pattern (IAGP)

abnormal olfactory receptor morphology (IAGP)

abnormal olfactory sensory neuron morphology (IAGP)

abnormal olfactory sensory neuron physiology (IAGP)

abnormal sensory neuron innervation pattern (IAGP)

decreased olfactory sensory neuron number (IAGP)

impaired olfaction (IAGP)

References

References - curated

#	Reference Title	Reference Citation
1.	Mouse MP Annotation Import Pipeline	RGD automated import pipeline
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:7528109	PMID:8570653	PMID:11739580	PMID:11802173	PMID:11875048	PMID:11943806	PMID:12194868	PMID:12477932	PMID:14611657	PMID:15042081	PMID:15173589	PMID:15178749
PMID:15186781	PMID:15186782	PMID:15737743	PMID:16531066	PMID:17079653	PMID:17350283	PMID:17472961	PMID:17521568	PMID:17581954	PMID:18353676	PMID:18498741	PMID:18854508
PMID:19200072	PMID:20346765	PMID:20624980	PMID:21123261	PMID:21873635	PMID:22910355	PMID:22926192	PMID:23596334	PMID:23884929	PMID:24211402	PMID:24211702	PMID:24292232
PMID:24312457	PMID:24913191	PMID:25550517	PMID:25568110	PMID:26100963	PMID:26365258	PMID:26420875	PMID:26961953	PMID:27396335	PMID:27466441	PMID:27578798	PMID:27844052
PMID:28262096	PMID:28683263	PMID:28933695	PMID:29078327	PMID:29407371	PMID:30061191	PMID:30482691	PMID:31171707	PMID:32209480	PMID:32295537	PMID:33906971

Genomics

Variants

Variants in Or8a1
38 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	71
Count of miRNA genes:	70
Interacting mature miRNAs:	71
Transcripts:	ENSMUST00000104875
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
13504833	Bglu19_m	blood glucose level 19 (mouse)					9	9910768	43910768	Mouse
1300532	Tbs2_m	tuberculosis severity 2 (mouse)			Not determined		9	12369970	46370114	Mouse
10043917	Obq37_m	obesity QTL 37 (mouse)			Not determined		9	13391175	47391175	Mouse
1357637	Si5lq2_m	serum IGFBP-5 level QTL 2 (mouse)			Not determined		9	15411751	49411890	Mouse
4141591	Cq4_m	cholesterol QTL 4 (mouse)			Not determined		9	15411751	49411890	Mouse
1301421	Lgth4_m	body length 4 (mouse)			Not determined		9	15411751	49411890	Mouse
4141447	Cfmq2_m	cystic fibrosis modifier QTL 2 (mouse)			Not determined		9	15411751	49411890	Mouse
12790993	Adq1_m	aortic diameter QTL 1 (mouse)					9	15749627	49749627	Mouse
11354951	Pdcc3_m	plasmacytoid dentritic cell compartment 3 (mouse)					9	15749627	49749627	Mouse
12790997	Adq2_m	aortic diameter QTL 2 (mouse)					9	15749627	49749627	Mouse
12880415	V125Dq7_m	vitamin D active form serum level QTL 7 (mouse)					9	16011296	50011296	Mouse
12880416	V125Dq8_m	vitamin D active form serum level QTL 8 (mouse)					9	16011296	50011296	Mouse
13504834	Hdlq109_m	HDL QTL 109 (mouse)					9	16709641	50709641	Mouse
1357465	Vtbt6_m	vertebral trabecular bone trait 6 (mouse)			Not determined		9	16978840	50978943	Mouse
1300643	Pvcan2_m	protection against vaginal candidiasis 2 (mouse)			Not determined		9	19943406	53943525	Mouse
1301439	Morph2_m	morphine antinociception 2 (mouse)			Not determined		9	20153362	54153492	Mouse
1301883	Skull12_m	skull morphology 12 (mouse)			Not determined		9	20306197	54306370	Mouse
1301045	Sluc10_m	susceptibility to lung cancer 10 (mouse)			Not determined		9	20306197	54306370	Mouse
10043950	Pbft5_m	percent body fat 5 (mouse)			Not determined		9	20306197	54306370	Mouse
4142352	Lmr17_m	leishmaniasis resistance 17 (mouse)			Not determined		9	20306197	54306370	Mouse
12904939	Edlmmq8_m	extensor digitorum longus muscle mass QTL 8 (mouse)					9	20852740	54852740	Mouse
13208563	Bmiq8_m	body mass index QTL 8 (mouse)					9	24911296	68907282	Mouse
11532712	Sluc39d_m	susceptibility to lung cancer 39d (mouse)					9	25587485	59587581	Mouse
11532696	Sluc39c_m	susceptibility to lung cancer 39c (mouse)					9	25587485	59587581	Mouse
11532694	Sluc39a_m	susceptibility to lung cancer 39a (mouse)					9	25587485	59587581	Mouse
11532695	Sluc39b_m	susceptibility to lung cancer 39b (mouse)					9	25587485	59587581	Mouse
10043987	Stheal13_m	soft tissue heal 13 (mouse)			Not determined		9	26796421	60796552	Mouse
1300932	Hdlq17_m	HDL QTL 17 (mouse)			Not determined		9	26796421	60796552	Mouse
10043867	Mtbcq9_m	multiple trait body composition QTL 9 (mouse)			Not determined		9	26796421	60796552	Mouse
10043878	Adip20_m	adiposity 20 (mouse)			Not determined		9	27251194	61251323	Mouse
1301000	Obq5_m	obesity QTL 5 (mouse)			Not determined		9	28503333	41799326	Mouse
10043847	Hdlq89_m	HDL QTL 89 (mouse)			Not determined		9	29292929	63293072	Mouse
1301782	Chol11_m	cholesterol 11 (mouse)			Not determined		9	29292929	63293072	Mouse
1301365	Ap5q_m	alcohol preference 5 QTL (mouse)			Not determined		9	30053164	64053277	Mouse
1558949	Igan3_m	IgA nephropathy 3 (mouse)			Not determined		9	30414694	40565914	Mouse
1357746	Vtbt7_m	vertebral trabecular bone trait 7 (mouse)			Not determined		9	30739915	64740021	Mouse
1302180	Actd4_m	activity-distance traveled 4 (mouse)			Not determined		9	32434563	66434857	Mouse
4141148	Cq5_m	cholesterol QTL 5 (mouse)			Not determined		9	32452421	66452546	Mouse
1301692	Hts_m	hypothermia sensitivity (mouse)			Not determined		9	32511172	66511421	Mouse
4141323	Ptnu3_m	proteinuria 3 (mouse)			Not determined		9	32889702	66889836	Mouse
1357709	Si5lq3_m	serum IGFBP-5 level QTL 3 (mouse)			Not determined		9	33111025	67111140	Mouse
1558872	Ibdq1_m	inflammatory bowel disease QTL 1 (mouse)			Not determined		9	33978840	73439255	Mouse
1357682	Phdlc1_m	plasma HDL cholesterol 1 (mouse)			Not determined		9	34104619	42764866	Mouse
1301252	Etohc3_m	ethanol consumption 3 (mouse)			Not determined		9	35034478	69034599	Mouse
1301972	Cocrb8_m	cocaine related behavior 8 (mouse)			Not determined		9	35034478	69034599	Mouse
1558968	Tbdr1_m	body temperature response to dietary restriction, QTL 1 (mouse)			Not determined		9	35034478	69034599	Mouse
10045613	Rapop7_m	radiation-induced apoptosis 6 (mouse)			Not determined		9	36736243	49420511	Mouse
1301501	Lmr2_m	leishmaniasis resistance 2 (mouse)			Not determined		9	36943406	50111140	Mouse
1301007	Pid2_m	prion incubation determinant 2 (mouse)			Not determined		9	37153362	44251323	Mouse
4142042	Alpq3_m	alcohol preference QTL 3 (mouse)			Not determined		9	37306197	98701707	Mouse

Markers in Region

UniSTS:485259

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	9	37,730,053 - 37,730,981	UniSTS	GRCm38
GRCm38	9	37,711,348 - 37,712,277	UniSTS	GRCm38
MGSCv37	9	37,537,638 - 37,538,566	UniSTS	GRCm37
MGSCv37	9	37,518,933 - 37,519,862	UniSTS	GRCm37
Celera	9	34,948,089 - 34,949,018	UniSTS
Celera	9	34,929,399 - 34,930,328	UniSTS
Cytogenetic Map	9	A4	UniSTS

UniSTS:494408

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	9	37,729,977 - 37,731,061	UniSTS	GRCm38
MGSCv37	9	37,537,562 - 37,538,646	UniSTS	GRCm37
Celera	9	34,948,013 - 34,949,098	UniSTS
Cytogenetic Map	9	A4	UniSTS

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_207664	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NR_160653	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC160125	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF281061	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY073205	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY245537	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY318055	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC138117	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC138118	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U28782	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSMUST00000211893 ⟹ ENSMUSP00000148694

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	9	37,641,273 - 37,642,400 (-)	Ensembl
GRCm38.p6 Ensembl	9	37,729,977 - 37,731,104 (-)	Ensembl

RefSeq Acc Id:

NR_160653

RefSeq Status:

VALIDATED

Type:

NON-CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	9	37,641,273 - 37,642,357 (-)	NCBI
GRCm38	9	37,729,977 - 37,731,061 (-)	NCBI

Sequence:

show sequence

AACCAGCTCTCCAAGCAGGGCAAGAACAGCCATTCACAAACTCCTTCTCTCCCACCACACAGGC
TTCCCACCCAGACACAATGACTGCAGAGAATCAATCTACAGTGACAGAGTTTATCCTCGGGGGG
CTAACTAACAGGCCAGAGCTCCAGCTACCCCTCTTCCTCCTCTTTCTGGGGATCCTCGTAGTCA
CCATGGTAGGAAACCTGGGCATGATCACCTTGATTGGACTCAACTCACAGCTTCACACCCCCAT
GTACTTCTTCCTCAGTAACCTGTCACTCGTGGATCTCTGCTACTCCTCTGTCATTACCCCTAAA
ATGCTCATCAACTTTGTGGCCCAAAGAAACCTCATCTCCTATGTGGGGTGCATGTCTCAGCTAT
ACTTCTTCCTGGTTTTCGTCATTGCTGAGTGTTACATGCTCACTGTGATGGCCTATGACCGCTA
TGTGGCCATCTGTCAACCCTTGCTTTATAACATCATCATGTCTCCTGCCCTCTGCTCTCTGCTG
GTGGCTTTTGTCTATGCCGTAGGACTCATCGGTTCAGCAATTGAGACTGGCCTCATGTTGAAAT
TAAACTATTGTGAGGACCTCATCAGCCACTACTTCTGTGACATCCTCCCCCTCATGAAGCTCTC
TTGCTCTAGTACCTATGATGTAGAAATGGCTGTCTTCTTTTTAGCTGGATTTGACATTATCGTC
ACAAGCTTAACCGTACTCATTTCCTATGCATTCATCCTGTCCAGCATCCTTCGCATCAGCTCCA
ACGAGGGCAGGTCCAAAGCCTTCAGCACCTGCAGCTCCCACTTTGCAGCTGTGGCTTGTTCTAT
GGATCCACAGCATTCATGTACTTAAAGCCTTCTACAGCTAGTTCCCTGGCCCGGGAGAATGTAG
CTTCTGTGTTCTACACCACAGTGATCCCCATGCTCAACCCCCTGATCTACAGCCTGAGAAACAA
GGAGGTGAAGACCGCACTGGACAAAACACTGAGGAGAAAAGTCTTTTGATGTAAATGCTGATCT
TTCTTCATGTAAAAGTAAGTGGTTATGCACACCTGTATGATAACCTCTGCAAGCTCACCCA

hide sequence

Protein Sequences


Protein RefSeqs	NP_997547	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAC52405	(Get FASTA)	NCBI Sequence Viewer
	AAG29379	(Get FASTA)	NCBI Sequence Viewer
	AAI38118	(Get FASTA)	NCBI Sequence Viewer
	AAI38119	(Get FASTA)	NCBI Sequence Viewer
	AAL60868	(Get FASTA)	NCBI Sequence Viewer
	AAP45845	(Get FASTA)	NCBI Sequence Viewer
	AAP71352	(Get FASTA)	NCBI Sequence Viewer
	Q60893	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

ENSMUSP00000148694 ⟸ ENSMUST00000211893

Protein Domains

G-protein coupled receptors family 1 profile

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q60893-F1-model_v2	AlphaFold	Q60893	1-309	view protein structure

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:2661338	AgrOrtholog
Ensembl Genes	ENSMUSG00000110526	Ensembl, ENTREZGENE
Ensembl Transcript	ENSMUST00000211893	ENTREZGENE
Gene3D-CATH	Rhodopsin 7-helix transmembrane proteins	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	GPCR_Rhodpsn	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	GPCR_Rhodpsn_7TM	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Olfact_rcpt	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	mmu:406176	UniProtKB/Swiss-Prot
MGD	MGI:2661338	ENTREZGENE
NCBI Gene	406176	ENTREZGENE
PANTHER	OLFACTORY RECEPTOR	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	OLFACTORY RECEPTOR 8A1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	7tm_4	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Or8a1	PhenoGen
PRINTS	GPCRRHODOPSN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	OLFACTORYR	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	G_PROTEIN_RECEP_F1_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	G_PROTEIN_RECEP_F1_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	Family A G protein-coupled receptor-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	B2RQX1	ENTREZGENE
	OL151_MOUSE	UniProtKB/Swiss-Prot, ENTREZGENE
	Q7TMN3_MOUSE	UniProtKB/TrEMBL
	Q7TRE7	ENTREZGENE
	Q9EQG1	ENTREZGENE, UniProtKB/TrEMBL
	Q9ERU6	ENTREZGENE
UniProt Secondary	B2RQX1	UniProtKB/Swiss-Prot
	Q7TRE7	UniProtKB/Swiss-Prot
	Q9ERU6	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2022-05-24	Or8a1	olfactory receptor family 8 subfamily A member 1	Olfr151	olfactory receptor 151	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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