Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-catechin | multiple interactions | ISO | SEH1L (Homo sapiens) | 6480464 | [Catechin co-treated with Grape Seed Proanthocyanidins] results in increased expression of SEH1L mRNA | CTD | PMID:24763279 | 1,2-dimethylhydrazine | decreases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of SEH1L mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of SEH1L mRNA | CTD | PMID:22206623 | 17beta-estradiol | decreases expression | ISO | Seh1l (Rattus norvegicus) | 6480464 | Estradiol results in decreased expression of SEH1L mRNA | CTD | PMID:32145629 | 17beta-estradiol | increases expression | ISO | SEH1L (Homo sapiens) | 6480464 | Estradiol results in increased expression of SEH1L mRNA | CTD | PMID:31614463 | 2,2',4,4'-Tetrabromodiphenyl ether | affects expression | EXP | | 6480464 | 2 more ... | CTD | PMID:30294300 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of SEH1L mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SEH1L mRNA | CTD | PMID:15034205 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | AHR protein inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of SEH1L mRNA] | CTD | PMID:15034205 | 2,4,6-tribromophenol | decreases expression | ISO | SEH1L (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | 2-hydroxypropanoic acid | decreases expression | ISO | SEH1L (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of SEH1L mRNA | CTD | PMID:30851411 | 4,4'-sulfonyldiphenol | decreases methylation | ISO | SEH1L (Homo sapiens) | 6480464 | bisphenol S results in decreased methylation of SEH1L gene | CTD | PMID:31601247 | acrolein | multiple interactions | ISO | SEH1L (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of SEH1L mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of SEH1L mRNA | CTD | PMID:32699268 | all-trans-retinoic acid | decreases expression | ISO | SEH1L (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of SEH1L mRNA | CTD | PMID:21934132 and PMID:33167477 | alpha-pinene | multiple interactions | ISO | SEH1L (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of SEH1L mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of SEH1L mRNA | CTD | PMID:32699268 | antirheumatic drug | decreases expression | ISO | SEH1L (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of SEH1L mRNA | CTD | PMID:24449571 | aristolochic acid A | decreases expression | ISO | SEH1L (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of SEH1L mRNA | CTD | PMID:33212167 | benzo[a]pyrene | multiple interactions | EXP | | 6480464 | AHR protein inhibits the reaction [Benzo(a)pyrene results in increased expression of SEH1L mRNA] | CTD | PMID:15034205 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of SEH1L mRNA | CTD | PMID:15034205 and PMID:22228805 | bisphenol A | decreases expression | ISO | SEH1L (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of SEH1L mRNA | CTD | PMID:29275510 | bisphenol A | increases methylation | ISO | SEH1L (Homo sapiens) | 6480464 | bisphenol A results in increased methylation of SEH1L gene | CTD | PMID:31601247 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of SEH1L mRNA | CTD | PMID:33221593 | bisphenol A | increases expression | ISO | Seh1l (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of SEH1L mRNA | CTD | PMID:32145629 | bisphenol A | affects expression | ISO | Seh1l (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of SEH1L mRNA | CTD | PMID:30816183 | carbon nanotube | increases expression | EXP | | 6480464 | Nanotubes and Carbon results in increased expression of SEH1L mRNA | CTD | PMID:25554681 | cisplatin | decreases expression | ISO | SEH1L (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of SEH1L mRNA | CTD | PMID:27594783 | cobalt dichloride | decreases expression | ISO | SEH1L (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of SEH1L mRNA | CTD | PMID:19320972 and PMID:19376846 | copper(II) sulfate | increases expression | ISO | SEH1L (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of SEH1L mRNA | CTD | PMID:19549813 | cyclosporin A | decreases expression | EXP | | 6480464 | Cyclosporine results in decreased expression of SEH1L mRNA | CTD | PMID:19770486 | ethyl methanesulfonate | decreases expression | ISO | SEH1L (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in decreased expression of SEH1L mRNA | CTD | PMID:23649840 | folic acid | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of SEH1L mRNA | CTD | PMID:22206623 | formaldehyde | decreases expression | ISO | SEH1L (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of SEH1L mRNA | CTD | PMID:23649840 | FR900359 | increases phosphorylation | ISO | SEH1L (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of SEH1L protein | CTD | PMID:37730182 | hydrogen peroxide | affects expression | ISO | SEH1L (Homo sapiens) | 6480464 | Hydrogen Peroxide affects the expression of SEH1L mRNA | CTD | PMID:20044591 | ivermectin | decreases expression | ISO | SEH1L (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of SEH1L protein | CTD | PMID:32959892 | menadione | affects expression | ISO | SEH1L (Homo sapiens) | 6480464 | Vitamin K 3 affects the expression of SEH1L mRNA | CTD | PMID:20044591 | methyl methanesulfonate | decreases expression | ISO | SEH1L (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of SEH1L mRNA | CTD | PMID:23649840 | methylmercury chloride | increases expression | ISO | SEH1L (Homo sapiens) | 6480464 | methylmercuric chloride results in increased expression of SEH1L mRNA | CTD | PMID:28001369 | nickel atom | decreases expression | ISO | SEH1L (Homo sapiens) | 6480464 | Nickel results in decreased expression of SEH1L mRNA | CTD | PMID:23195993 | nickel atom | increases expression | ISO | SEH1L (Homo sapiens) | 6480464 | Nickel results in increased expression of SEH1L mRNA | CTD | PMID:24768652 and PMID:25583101 | ozone | multiple interactions | ISO | SEH1L (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of SEH1L mRNA more ... | CTD | PMID:32699268 | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of SEH1L mRNA | CTD | PMID:17562736 | paracetamol | decreases expression | ISO | SEH1L (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of SEH1L mRNA | CTD | PMID:21420995 | pentachlorophenol | increases expression | EXP | | 6480464 | Pentachlorophenol results in increased expression of SEH1L mRNA | CTD | PMID:23892564 | perfluorooctanoic acid | increases expression | EXP | | 6480464 | perfluorooctanoic acid results in increased expression of SEH1L protein | CTD | PMID:37422089 | phenobarbital | decreases expression | EXP | | 6480464 | Phenobarbital results in decreased expression of SEH1L mRNA | CTD | PMID:23091169 | pirinixic acid | increases expression | EXP | | 6480464 | pirinixic acid results in increased expression of SEH1L mRNA | CTD | PMID:23811191 | potassium dichromate | decreases expression | EXP | | 6480464 | Potassium Dichromate results in decreased expression of SEH1L mRNA | CTD | PMID:23608068 | progesterone | decreases expression | ISO | SEH1L (Homo sapiens) | 6480464 | Progesterone results in decreased expression of SEH1L mRNA | CTD | PMID:18037150 | rac-lactic acid | decreases expression | ISO | SEH1L (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of SEH1L mRNA | CTD | PMID:30851411 | resveratrol | multiple interactions | ISO | SEH1L (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of SEH1L mRNA | CTD | PMID:23557933 | sodium arsenite | multiple interactions | ISO | SEH1L (Homo sapiens) | 6480464 | sodium arsenite promotes the reaction [SEH1L protein binds to CAPRIN1 protein] | CTD | PMID:33939924 | sunitinib | increases expression | ISO | SEH1L (Homo sapiens) | 6480464 | Sunitinib results in increased expression of SEH1L mRNA | CTD | PMID:31533062 | tacrolimus hydrate | increases expression | EXP | | 6480464 | Tacrolimus results in increased expression of SEH1L mRNA | CTD | PMID:25270620 | valproic acid | decreases expression | EXP | | 6480464 | Valproic Acid results in decreased expression of SEH1L mRNA | CTD | PMID:19136453 and PMID:21427059 | valproic acid | decreases methylation | ISO | SEH1L (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of SEH1L gene | CTD | PMID:29154799 | valproic acid | affects expression | ISO | SEH1L (Homo sapiens) | 6480464 | Valproic Acid affects the expression of SEH1L mRNA | CTD | PMID:25979313 | valproic acid | decreases expression | ISO | SEH1L (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of SEH1L mRNA | CTD | PMID:23179753 and PMID:27188386 | |