Mroh5 (maestro heat-like repeat family member 5) - Rat Genome Database

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Gene: Mroh5 (maestro heat-like repeat family member 5) Mus musculus
Analyze
Symbol: Mroh5
Name: maestro heat-like repeat family member 5
RGD ID: 1615592
MGI Page MGI
Description: Predicted to be active in cytoplasm. Orthologous to human MROH5 (maestro heat like repeat family member 5 (gene/pseudogene)).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Gm628; hypothetical protein LOC268816; uncharacterized protein LOC268816
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391573,658,785 - 73,711,520 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1573,631,916 - 73,711,548 (-)EnsemblGRCm39 Ensembl
GRCm381573,786,936 - 73,839,671 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1573,760,067 - 73,839,699 (-)EnsemblGRCm38mm10GRCm38
MGSCv371573,617,366 - 73,670,101 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361573,614,191 - 73,666,926 (-)NCBIMGSCv36mm8
Celera1575,292,062 - 75,350,235 (-)NCBICelera
Cytogenetic Map15D3NCBI
cM Map1534.06NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:16141072   PMID:16141073   PMID:18799693   PMID:21677750   PMID:21873635  


Genomics

Comparative Map Data
Mroh5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391573,658,785 - 73,711,520 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1573,631,916 - 73,711,548 (-)EnsemblGRCm39 Ensembl
GRCm381573,786,936 - 73,839,671 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1573,760,067 - 73,839,699 (-)EnsemblGRCm38mm10GRCm38
MGSCv371573,617,366 - 73,670,101 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361573,614,191 - 73,666,926 (-)NCBIMGSCv36mm8
Celera1575,292,062 - 75,350,235 (-)NCBICelera
Cytogenetic Map15D3NCBI
cM Map1534.06NCBI
MROH5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388141,433,825 - 141,507,229 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8141,433,829 - 141,507,230 (-)EnsemblGRCh38hg38GRCh38
GRCh378142,443,925 - 142,517,329 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368142,513,111 - 142,586,512 (-)NCBINCBI36Build 36hg18NCBI36
Celera8138,610,353 - 138,681,759 (-)NCBICelera
Cytogenetic Map8q24.3NCBI
HuRef8137,798,003 - 137,836,354 (-)NCBIHuRef
HuRef8137,761,305 - 137,795,358 (-)NCBIHuRef
CHM1_18142,484,157 - 142,557,292 (-)NCBICHM1_1
T2T-CHM13v2.08142,561,183 - 142,635,781 (-)NCBIT2T-CHM13v2.0
Mroh5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87107,551,767 - 107,626,899 (-)NCBIGRCr8
mRatBN7.27105,662,737 - 105,737,820 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7105,662,744 - 105,730,060 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.07115,003,594 - 115,079,728 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7115,033,025 - 115,045,802 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.07114,924,955 - 115,000,223 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47111,469,995 - 111,544,323 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera7102,068,757 - 102,144,721 (-)NCBICelera
Cytogenetic Map7q34NCBI
Mroh5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955454442,757 - 504,231 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955454442,857 - 503,429 (-)NCBIChiLan1.0ChiLan1.0
LOC100987797
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27158,830,349 - 158,905,179 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan18134,360,794 - 134,435,639 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08138,109,975 - 138,183,612 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18141,189,759 - 141,262,348 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8141,189,814 - 141,262,269 (-)Ensemblpanpan1.1panPan2
MROH5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11335,887,434 - 35,957,954 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1335,889,010 - 35,957,861 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1335,746,540 - 35,817,459 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01336,273,053 - 36,344,038 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1336,274,629 - 36,344,783 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11335,993,153 - 36,064,062 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01336,084,735 - 36,153,919 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01336,503,493 - 36,574,457 (-)NCBIUU_Cfam_GSD_1.0
LOC101965287
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244053032,552,867 - 2,614,461 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049364709,991,758 - 10,040,617 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MROH5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl42,282,120 - 2,343,887 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.142,282,120 - 2,344,176 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.241,538,079 - 1,569,070 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103237517
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18135,673,927 - 135,746,166 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl8135,674,055 - 135,744,562 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660394,378,617 - 4,454,096 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mroh5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473514,914,479 - 14,961,747 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Mroh5
1637 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1394
Count of miRNA genes:637
Interacting mature miRNAs:784
Transcripts:ENSMUST00000071419, ENSMUST00000110021, ENSMUST00000126186, ENSMUST00000136698, ENSMUST00000151999
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4141952W3q7_mweight 3 weeks QTL 7 (mouse)Not determined348969478601286Mouse
4142252Tailaq4_mtail length adjusted QTL 4 (mouse)Not determined348969478601286Mouse
4142448Tailq6_mtail length QTL 6 (mouse)Not determined348969478601286Mouse
1357559Scfq2_msubcutaneous fat pad weight QTL 2 (mouse)Not determined15348969478601286Mouse
1357659Epfpq4_mepididymal fat percentage QTL 4 (mouse)Not determined15348969478601286Mouse
27226786Feml11_mfemur length 11, 5 week (mouse)15612948175871849Mouse
27095932Ulnl11_mulna length 11, 16 week (mouse)15612948176384200Mouse
27226717Tibw4_mtibia width 4, proximal, 10 week (mouse)15612948178684200Mouse
27226734Tibmd5_mtibia midshaft diameter 5, 10 week (mouse)15612948186684201Mouse
26884442Sklq6_mskull length QTL 6, 5 week (mouse)156129481100797881Mouse
27226721Tibw8_mtibia width 8, proximal, 16 week (mouse)15692948175871849Mouse
27226773Tibl16_mtibia length 16, 10 week (mouse)15692948175871849Mouse
27226777Tibl8_mtibia length 8, 5 week (mouse)15692948184584201Mouse
1301433Rapop5_mradiation-induced apoptosis 5 (mouse)Not determined15927302279474762Mouse
1357526Hyplip2_mhyperlipidemia 2 (mouse)Not determined1512402203102896555Mouse
26884425Cvht2_mcranial vault height 2, 5 week (mouse)1528800146102008435Mouse
26884392Humsd8_mhumerus midshaft diameter 8, 16 week (mouse)152930014676084200Mouse
1558985Eae32_mexperimental allergic encephalomyelitis susceptibility 32 (mouse)Not determined1532578416103425899Mouse
27226729Tibmd2_mtibia midshaft diameter 2, 5 week (mouse)153800024486684201Mouse
26884402Cvht9_mcranial vault height 9, 16 week (mouse)154216339695497881Mouse
1357703Vtbt17_mvertebral trabecular bone trait 17 (mouse)Not determined154455331378553437Mouse
1301568Tria2_mT-cell receptor induced activation 2 (mouse)Not determined154485914178859281Mouse
1357756Alaa4_malopecia areata 4 (mouse)Not determined154638964680389845Mouse
10755515Amzn3_manatomical modifier of Zfp423 3 (mouse)154638964680389845Mouse
1301006Hfib1_mhepatic fibrogenesis 1 (mouse)Not determined154730633481306479Mouse
1301860Gct3_mgranulosa cell tumorigenesis 3 (mouse)Not determined154740959681409691Mouse
26884397Humsd5_mhumerus midshaft diameter 5, 10 week (mouse)154836339698397881Mouse
26884399Humsd1_mhumerus midshaft diameter 1, 5 week (mouse)1548363396101708435Mouse
1301429Pcir3_mperiosteal circumference 3 (mouse)Not determined154846536282465496Mouse
1301779Dpml_mdopamine loss (mouse)Not determined155100469476794493Mouse
4142198Hbtq_mhabituation QTL (mouse)Not determined155116070885160833Mouse
10045637Heal27_mwound healing/regeneration 29 (mouse)Not determined155141836185418511Mouse
10412067Pain2_mpain 2 (mouse)Not determined155164533985645626Mouse
1302080Szs13_mseizure susceptibility 13 (mouse)Not determined155168583285694449Mouse
1301708Cocrb14_mcocaine related behavior 14 (mouse)Not determined155180651585806651Mouse
38501067Tip3_mtuberculosis immunophenotype 3, IFN-g level (mouse)155356339689584203Mouse
13504731Cath5_mcarotid atherosclerosis 5 (mouse)155478912988789129Mouse
1302074Bmd4_mbone mineral density 4 (mouse)Not determined1556186708103425899Mouse
27095936Ulnl4_mulna length 4, 5 week (mouse)155676339687684201Mouse
1300800Ses3_msalmonella enteritidis susceptibility 3 (mouse)Not determined155711700591117153Mouse
1357407Pfat4_mpredicted fat percentage 4 (mouse)8.6Body fat amountpredicted fat percentage155711700591117153Mouse
12880420V25Dq8_mvitamin D inactive form serum level QTL 8 (mouse)156158420095584200Mouse
1301601Faq9_mfluctuating asymmetry QTL 9 (mouse)Not determined156316390397163995Mouse
1558786Msq1_mMAV-1 susceptibility QTL 1 (mouse)Not determined156338964681086436Mouse
1302197Bhr2_mbronchial hyperresponsiveness 2 (mouse)Not determined1564306334103425899Mouse
4141135Cia35_mcollagen induced arthritis 35 (mouse)Not determined156481182698811946Mouse
1301119Drb7_mdopamine receptor binding 7 (mouse)Not determined156533657899341028Mouse
1301171Brm2_mbrachyury modifier 2 (mouse)Not determined156552537699525499Mouse
4141921Pstc3_mperiosteal circumference 3 (mouse)Not determined1567270698101270847Mouse
1300627Sluc26_msusceptibility to lung cancer 26 (mouse)Not determined1570345653104073951Mouse
1300648Dbsty4_mdiabesity 4 (mouse)Not determined1570349271104073951Mouse
1300726Pitm4_mprion incubation time 4 (mouse)Not determined1570349271104073951Mouse
25671381Hrsq3_mhost response to SARS QTL 3, eosinophilia (mouse)157214453975844833Mouse
1300844Emo2_memotionality 2 (mouse)Not determined157237245976794493Mouse
1302002Cocia2_mcocaine induced activation 2 (mouse)Not determined157237245979899178Mouse
14747011Mancz13_mmandible centroid size 13 (mouse)1572382669104073951Mouse
12791003Aath8_maortic arch atherosclerosis 8 (mouse)1573430144104073951Mouse

Markers in Region
Ndufb4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381925,033,271 - 25,033,509UniSTSGRCm38
GRCm381573,809,529 - 73,809,767UniSTSGRCm38
MGSCv371925,107,761 - 25,107,999UniSTSGRCm37
MGSCv371573,639,959 - 73,640,197UniSTSGRCm37
Cytogenetic Map15D3UniSTS
Cytogenetic Map16B3UniSTS
Cytogenetic Map19BUniSTS
cM Map16 UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000071419   ⟹   ENSMUSP00000071366
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1573,658,261 - 73,711,520 (-)Ensembl
GRCm38.p6 Ensembl1573,786,412 - 73,839,671 (-)Ensembl
RefSeq Acc Id: ENSMUST00000110021   ⟹   ENSMUSP00000105648
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1573,658,785 - 73,691,259 (-)Ensembl
GRCm38.p6 Ensembl1573,786,936 - 73,819,410 (-)Ensembl
RefSeq Acc Id: ENSMUST00000136698
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1573,668,585 - 73,711,548 (-)Ensembl
GRCm38.p6 Ensembl1573,796,736 - 73,839,699 (-)Ensembl
RefSeq Acc Id: ENSMUST00000151999   ⟹   ENSMUSP00000118236
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1573,633,259 - 73,702,832 (-)Ensembl
GRCm38.p6 Ensembl1573,761,410 - 73,830,983 (-)Ensembl
RefSeq Acc Id: ENSMUST00000238402   ⟹   ENSMUSP00000158590
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1573,631,916 - 73,702,832 (-)Ensembl
GRCm38.p6 Ensembl1573,760,067 - 73,830,983 (-)Ensembl
RefSeq Acc Id: NM_001033365   ⟹   NP_001028537
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391573,658,785 - 73,711,520 (-)NCBI
GRCm381573,786,936 - 73,839,671 (-)ENTREZGENE
MGSCv371573,617,366 - 73,670,101 (-)RGD
Celera1575,292,062 - 75,350,235 (-)RGD
cM Map15 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001368162   ⟹   NP_001355091
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391573,658,785 - 73,711,520 (-)NCBI
GRCm381573,786,936 - 73,839,671 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_001028537   ⟸   NM_001033365
- Peptide Label: isoform 2
- UniProtKB: Q3TY91 (UniProtKB/TrEMBL),   B7ZWG8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001355091   ⟸   NM_001368162
- Peptide Label: isoform 1
- UniProtKB: B9EKG2 (UniProtKB/TrEMBL),   B7ZWG8 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSMUSP00000071366   ⟸   ENSMUST00000071419
RefSeq Acc Id: ENSMUSP00000105648   ⟸   ENSMUST00000110021
RefSeq Acc Id: ENSMUSP00000118236   ⟸   ENSMUST00000151999
RefSeq Acc Id: ENSMUSP00000158590   ⟸   ENSMUST00000238402

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A571BEG0-F1-model_v2 AlphaFold A0A571BEG0 1-1293 view protein structure

Promoters
RGD ID:8683932
Promoter ID:EPDNEW_M19997
Type:multiple initiation site
Name:Mroh5_1
Description:Mus musculus maestro heat-like repeat family member 5 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M19998  EPDNEW_M19999  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381573,809,933 - 73,809,993EPDNEW
RGD ID:8683934
Promoter ID:EPDNEW_M19998
Type:initiation region
Name:Mroh5_2
Description:Mus musculus maestro heat-like repeat family member 5 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M19997  EPDNEW_M19999  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381573,831,014 - 73,831,074EPDNEW
RGD ID:8683936
Promoter ID:EPDNEW_M19999
Type:single initiation site
Name:Mroh5_3
Description:Mus musculus maestro heat-like repeat family member 5 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M19997  EPDNEW_M19998  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381573,839,670 - 73,839,730EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2685474 AgrOrtholog
Ensembl Genes ENSMUSG00000072487 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000071419 ENTREZGENE
  ENSMUST00000071419.12 UniProtKB/TrEMBL
  ENSMUST00000110021 ENTREZGENE
  ENSMUST00000110021.3 UniProtKB/TrEMBL
  ENSMUST00000151999.9 UniProtKB/TrEMBL
  ENSMUST00000238402.2 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  Maestro_heat-like_prot UniProtKB/TrEMBL
  Maestro_HEAT_rpt UniProtKB/TrEMBL
KEGG Report mmu:268816 UniProtKB/TrEMBL
MGD MGI:2685474 ENTREZGENE
NCBI Gene 268816 ENTREZGENE
PANTHER MAESTRO HEAT-LIKE REPEAT FAMILY MEMBER 5 UniProtKB/TrEMBL
  PTHR23120 UniProtKB/TrEMBL
Pfam Maestro_HEAT UniProtKB/TrEMBL
PhenoGen Mroh5 PhenoGen
Superfamily-SCOP ARM-type_fold UniProtKB/TrEMBL
UniProt A0A571BEG0_MOUSE UniProtKB/TrEMBL
  B7ZWG8 ENTREZGENE, UniProtKB/TrEMBL
  B9EKG2 ENTREZGENE, UniProtKB/TrEMBL
  E9PUJ8_MOUSE UniProtKB/TrEMBL
  Q3TY91 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-01-08 Mroh5  maestro heat-like repeat family member 5  Gm628  predicted gene 628  Symbol and/or name change 5135510 APPROVED