Them5 (thioesterase superfamily member 5)

Gene: Them5 (thioesterase superfamily member 5) Mus musculus

Analyze

Symbol:

Them5

Name:

thioesterase superfamily member 5

RGD ID:

1615115

MGI Page

MGI

Description:

Predicted to enable long-chain fatty acyl-CoA hydrolase activity. Involved in cardiolipin acyl-chain remodeling. Located in mitochondrion. Is expressed in anterior naris; epidermis; external naris; and oral epithelium. Orthologous to human THEM5 (thioesterase superfamily member 5).

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

1110007B02Rik; 1110038F21Rik; acyl-CoA thioesterase THEM5; acyl-coenzyme A thioesterase 15; acyl-coenzyme A thioesterase THEM5

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	THEM5 (thioesterase superfamily member 5)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):	Them5 (thioesterase superfamily member 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Them5 (thioesterase superfamily member 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	THEM5 (thioesterase superfamily member 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	THEM5 (thioesterase superfamily member 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Them5 (thioesterase superfamily member 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	THEM5 (thioesterase superfamily member 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Them5 (thioesterase superfamily member 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Them5 (thioesterase superfamily member 5)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	THEM5 (thioesterase superfamily member 5)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	them4 (thioesterase superfamily member 4)	Alliance	DIOPT (OrthoFinder\|ZFIN)
Saccharomyces cerevisiae (baker's yeast):	FMP10	Alliance	DIOPT (Ensembl Compara\|OrthoFinder)
Saccharomyces cerevisiae (baker's yeast):	MRX3	Alliance	DIOPT (Ensembl Compara\|OrthoFinder)

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	94,249,406 - 94,254,659 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	94,249,406 - 94,254,659 (+)	Ensembl		GRCm39 Ensembl
GRCm38	3	94,342,099 - 94,347,352 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	94,342,099 - 94,347,352 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	3	94,146,021 - 94,151,272 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	3	94,427,503 - 94,432,753 (+)	NCBI		MGSCv36	mm8
Celera	3	95,788,493 - 95,793,740 (+)	NCBI		Celera
Cytogenetic Map	3	F2.1	NCBI
cM Map	3	40.52	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

gastrointestinal stromal tumor (ISO)

genetic disease (ISO)

immunodeficiency 42 (ISO)

MHC class II deficiency (ISO)

parathyroid carcinoma (ISO)

severe congenital neutropenia 3 (ISO)

severe congenital neutropenia 5 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (EXP)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

17beta-estradiol 3-benzoate (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

3,7-dihydropurine-6-thione (ISO)

3-methylcholanthrene (ISO)

aldehydo-D-glucose (EXP)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (EXP,ISO)

bisphenol A (EXP,ISO)

CGP 52608 (ISO)

chloroprene (ISO)

copper atom (ISO)

copper(0) (ISO)

D-glucose (EXP)

dichloroacetic acid (EXP)

fulvestrant (ISO)

gentamycin (ISO)

glucose (EXP)

leflunomide (ISO)

mercaptopurine (ISO)

N-nitrosodiethylamine (EXP)

nitrofen (ISO)

paracetamol (ISO)

paraquat (ISO)

perfluorooctane-1-sulfonic acid (EXP)

phenobarbital (EXP)

propanal (ISO)

purine-6-thiol (ISO)

resveratrol (ISO)

sodium arsenite (ISO)

sodium fluoride (EXP)

testosterone (ISO)

tetrachloroethene (EXP)

tremolite asbestos (EXP)

trichloroethene (EXP,ISO)

uranium atom (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cardiolipin acyl-chain remodeling (IBA,IMP)

fatty acid metabolic process (IEA)

lipid metabolic process (IEA)

long-chain fatty-acyl-CoA metabolic process (IBA,ISO)

Cellular Component

mitochondrial matrix (IBA,ISO)

mitochondrion (HDA)

Molecular Function

hydrolase activity (IEA)

long-chain fatty acyl-CoA hydrolase activity (IBA,ISO)

protein binding (ISO)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

abnormal cellular respiration (IAGP)

abnormal mitochondrial morphology (IAGP)

abnormal mitochondrial shape (IAGP)

abnormal respiratory electron transport chain (IAGP)

decreased fatty acids level (IAGP)

hepatic steatosis (IAGP)

increased circulating free fatty acids level (IAGP)

increased mitochondrial size (IAGP)

References

References - curated

#	Reference Title	Reference Citation
1.	Mouse MP Annotation Import Pipeline	RGD automated import pipeline
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:10349636	PMID:11042159	PMID:11076861	PMID:11217851	PMID:12466851	PMID:12477932	PMID:16141072	PMID:16141073	PMID:18614015	PMID:21267068	PMID:21677750	PMID:21873635
PMID:22586271

Genomics

Comparative Map Data

Them5
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	94,249,406 - 94,254,659 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	94,249,406 - 94,254,659 (+)	Ensembl		GRCm39 Ensembl
GRCm38	3	94,342,099 - 94,347,352 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	94,342,099 - 94,347,352 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	3	94,146,021 - 94,151,272 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	3	94,427,503 - 94,432,753 (+)	NCBI		MGSCv36	mm8
Celera	3	95,788,493 - 95,793,740 (+)	NCBI		Celera
Cytogenetic Map	3	F2.1	NCBI
cM Map	3	40.52	NCBI

THEM5
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	151,847,101 - 151,853,712 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	151,847,101 - 151,853,712 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	151,819,577 - 151,826,188 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	150,084,844 - 150,092,797 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	1	124,934,271 - 124,940,820 (-)	NCBI		Celera
Cytogenetic Map	1	q21.3	NCBI
HuRef	1	123,196,563 - 123,203,112 (-)	NCBI		HuRef
CHM1_1	1	153,214,902 - 153,221,451 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	150,970,601 - 150,977,165 (-)	NCBI		T2T-CHM13v2.0

Them5
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	184,665,335 - 184,675,041 (+)	NCBI		GRCr8
mRatBN7.2	2	181,980,783 - 181,986,002 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	181,980,783 - 181,986,002 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	189,643,935 - 189,649,152 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	187,448,061 - 187,453,284 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	182,276,407 - 182,281,624 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	195,582,781 - 195,588,000 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	195,582,781 - 195,588,000 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	215,061,475 - 215,066,694 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	189,315,151 - 189,321,030 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	2	174,531,200 - 174,536,419 (+)	NCBI		Celera
Cytogenetic Map	2	q34	NCBI

Them5
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955589	565,182 - 574,872 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955589	546,592 - 571,844 (+)	NCBI	ChiLan1.0	ChiLan1.0

THEM5
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	97,967,502 - 97,977,408 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	97,718,686 - 97,735,803 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	127,205,721 - 127,212,112 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	130,849,797 - 130,856,529 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	130,849,815 - 130,856,523 (-)	Ensembl	panpan1.1		panPan2

THEM5
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	17	60,857,348 - 60,865,789 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	17	60,857,350 - 60,865,579 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	17	60,301,796 - 60,310,146 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	17	61,876,913 - 61,885,249 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	17	61,876,933 - 61,885,040 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	17	60,703,724 - 60,712,049 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	17	60,789,891 - 60,798,385 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	17	61,519,000 - 61,527,351 (-)	NCBI		UU_Cfam_GSD_1.0

Them5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	23,006,213 - 23,014,051 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936580	2,036,704 - 2,043,897 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936580	2,036,595 - 2,044,053 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

THEM5
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	97,332,432 - 97,359,428 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	97,319,579 - 97,358,602 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	106,343,969 - 106,383,109 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Them5
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624772	19,523,526 - 19,530,041 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624772	19,523,721 - 19,530,019 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Them5
131 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	285
Count of miRNA genes:	159
Interacting mature miRNAs:	161
Transcripts:	ENSMUST00000029794, ENSMUST00000128907
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
26884436	Zlq3_m	zygomatic length QTL 3, 10 week (mouse)					3	3265060	142405761	Mouse
4142399	Aec1_m	autoimmune exocrinopathy 1 (mouse)			Not determined			7586174	102690034	Mouse
26884427	Cvht4_m	cranial vault height 4, 10 week (mouse)					3	16054164	109707316	Mouse
13207570	Tcq12_m	total cholesterol QTL 12 (mouse)					3	16504164	130163649	Mouse
26884422	Cvht7_m	cranial vault height 7, 16 week (mouse)					3	28954149	118893649	Mouse
1302056	Orgwq4_m	organ weight QTL 4 (mouse)			Not determined		3	30067588	147304689	Mouse
1301705	Sles3_m	systemic lupus erythmatosus suppressor 3 (mouse)			Not determined		3	37174862	143353183	Mouse
13208566	Bmiq5_m	body mass index QTL 5 (mouse)					3	40954435	115793649	Mouse
26884380	Skwq1_m	skull length QTL 1, 5 week (mouse)					3	43954435	101607316	Mouse
26884378	Skwq6_m	skull length QTL 6, 10 week (mouse)					3	51907421	102307316	Mouse
26884382	Bzwq1_m	bi-zygomatic width QTL 1, 5 week (mouse)					3	52207421	137205761	Mouse
11039519	Ltpr3_m	Leishmania tropica response 3 (mouse)					3	56704102	100464137	Mouse
4141294	Bmd24_m	bone mineral density 24 (mouse)			Not determined		3	61740061	95740241	Mouse
1301971	Cia5_m	collagen induced arthritis QTL 5 (mouse)			Not determined		3	66046658	100046795	Mouse
25314313	Syncl1_m	synaptonemal complex length 1 (mouse)					3	67907333	128393649	Mouse
11251721	Ewc3_m	ethanol withdrawal and consumption 3 (mouse)					3	69568554	103568554	Mouse
1301791	Char4_m	P. chabaudi malaria resistance QTL 4 (mouse)			Not determined		3	69625509	100655290	Mouse
1301422	Sle11_m	systematic lupus erythematosus susceptibility 11 (mouse)			Not determined		3	70208904	104209042	Mouse
11049572	Lmr11c_m	leishmaniasis resistance 11c (mouse)					3	72139967	106140094	Mouse
1300982	Lmr11_m	leishmaniasis resistance 11 (mouse)			Not determined		3	72139967	106140094	Mouse
1300595	Tmevd2_m	Theiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 2 (mouse)			Not determined		3	75463302	109463549	Mouse
1301392	Eae3_m	susceptibility to experimental allergic encephalomyelitis 3 (mouse)			Not determined		3	79548730	113548837	Mouse
1301947	Pcfm3_m	periosteal circumference and femur length 3 (mouse)			Not determined		3	81084652	115084797	Mouse
1301904	Iba2_m	induction of brown adipocytes 2 (mouse)			Not determined		3	82147043	116147184	Mouse
11041900	Lmr11a_m	leishmaniasis resistance 11a (mouse)					3	83463991	117464137	Mouse
11039510	Ltpr3d_m	Leishmania tropica response 3d (mouse)					3	83463991	117464137	Mouse
11039511	Ltpr3c_m	Leishmania tropica response 3c (mouse)					3	83463991	117464137	Mouse
11039507	Ltpr3g_m	Leishmania tropica response 3g (mouse)					3	83463991	117464137	Mouse
11039508	Ltpr3f_m	Leishmania tropica response 3f (mouse)					3	83463991	117464137	Mouse
11039509	Ltpr3e_m	Leishmania tropica response 3e (mouse)					3	83463991	117464137	Mouse
11039512	Ltpr3b_m	Leishmania tropica response 3b (mouse)					3	83463991	117464137	Mouse
1301272	Cfsw1_m	cystic fibrosis survival to weaning 1 (mouse)			Not determined		3	83882912	117883044	Mouse
4142099	Cq3_m	cholesterol QTL 3 (mouse)			Not determined		3	84888918	118889067	Mouse
14746984	Manh54_m	mandible shape 54 (mouse)					3	85289152	119289152	Mouse
1357583	Sle18_m	systematic lupus erythematosus susceptibility 18 (mouse)			Not determined		3	87208904	125316236	Mouse
12738440	Twq3_m	testis weight QTL 3 (mouse)					3	87228015	121228015	Mouse
4142178	Ctrq2_m	C. trachomatis resistance QTL 2 (mouse)			Not determined		3	89139967	137453008	Mouse
10766455	Sle22_m	systematic lupus erythematosus susceptibility 22 (mouse)					3	90376936	124377072	Mouse
14747001	Mancz4_m	mandible centroid size 4 (mouse)					3	90378017	124378017	Mouse
1301398	Rapop3_m	radiation-induced apoptosis 3 (mouse)			Not determined		3	90511217	100464137	Mouse
1302052	Etohcta4_m	ethanol conditioned taste aversion 4 (mouse)			Not determined		3	91000105	125008748	Mouse
1301349	Pgia26_m	proteoglycan induced arthritis 26 (mouse)			Not determined		3	92251533	126251650	Mouse

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_025416	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC164562	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK003517	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK004155	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK009228	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AV021934	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC046437	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466620	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSMUST00000029794 ⟹ ENSMUSP00000029794

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	3	94,249,406 - 94,254,659 (+)	Ensembl
GRCm38.p6 Ensembl	3	94,342,099 - 94,347,352 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000198083 ⟹ ENSMUSP00000142808

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	3	94,249,566 - 94,254,657 (+)	Ensembl
GRCm38.p6 Ensembl	3	94,342,259 - 94,347,350 (+)	Ensembl

RefSeq Acc Id:

NM_025416 ⟹ NP_079692

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	3	94,249,406 - 94,254,659 (+)	NCBI
GRCm38	3	94,342,099 - 94,347,352 (+)	ENTREZGENE
MGSCv37	3	94,146,021 - 94,151,272 (+)	RGD
Celera	3	95,788,493 - 95,793,742 (+)	ENTREZGENE
cM Map	3		ENTREZGENE

Sequence:

show sequence

CCAGCCCAGTCTTGCACAGTTTCTTCTTCAGCAGGAACTCTCTGCTAGAAGAAAGCCCGTGTTA
GGTGTGCCTGGTCCAAGCAAGGCTGCCTGGCACTCACTTGTCCTCTGGAGTCAGCCACTATTTA
TCCAAGCAAAGCCGGGATCCTGGCACTCAGCCATGTTGAGGACAAGTTTCCAGGGAGTGGCAAG
ACTTGTCCGCCACAAAGCTCTTTACAGAAGCCCCTGTCTCCTGCCCAGAGTCCACCTGGCCTCA
GCATTTGGTTCCTCCACAGAGTCCCTGGTTGCAAGATTCTGCCCAGAGAAGACAGATTTGAAAG
ATTATGCCCTTCCCAATGCCAGCTGGTGTTCAGATATGCTGAGTCTGTATCAAGAATTTCTGGA
AAAAACCAAATCAGGCGGCTGGATTAAACTACCCTCCTTCAAATCCAACAGAGATCATATCCAG
GGCCTTAAGCTCCCATTTGGGCTGGAAACTGCCTCAGACAAACAGGACTGGCGCCTCTTTACCA
GGTCCATACAACTGGAAGGACAAGGCTATGAATACGTCATCTTTTTCCACCCATCTGAGAAGAA
GTCTGTCTGTCTTTTCCAGCCAGGCCCCTACCTGGAGGGGGCACCAGGGTTTGCTCACGGAGGG
TCACTGGCAGCCTTGATGGATGAGACATATTCGAAAACTGCATATCTGGCTGGAGAAGGACTAT
TCACACTAAGTCTAAACATCAAGTTCAAAAACTTGATCCCCGTGGGCTCTTTGGCTGTCCTGGA
CATTCAAGTAGAAAAGATTGAAGACCAGAAACTCTACATGTCCTGCATCGCCCAGAGCAGAGAC
AAGCAGACCGTCTATGCCAAGTCCTCCGGTGTTTTCCTTCAGCTGCAGTTGGAAGAACAGTCCC
AGGAGCAATGACCTTGACCTTGATGACTCAGTGGCCACATAACAGACAAGGGTCCCCAGGAATC
AGGTGGCAGAGGAGGGAGAAAAAGGCATTTTTACCACCCCACGGTCAGTCCAAGAACCTTCTGT
AGTTGGAATCAAAATCGTCCGTAGGCCACAGATAACTCAGCAGTTAAGAACCCTAGCTGCTGCT
TGATTTCCAGCACCAACAAGGTGGTTCACAACCATCTGTAACTCCTGTCCCAGGGAATCCAATA
CCCTTTTCTGGCCTCCATGGAGTACCAGGTACACGTCCAGTGCCTTCCGTACAAACCCAACACC
CGTATACCTAAAAATAAATGAATGTTTTAAACCTT

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Protein Sequences


Protein RefSeqs	NP_079692	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH46437	(Get FASTA)	NCBI Sequence Viewer
	BAB22830	(Get FASTA)	NCBI Sequence Viewer
	BAB23196	(Get FASTA)	NCBI Sequence Viewer
	BAB26151	(Get FASTA)	NCBI Sequence Viewer
	EDL38720	(Get FASTA)	NCBI Sequence Viewer
	EDL38721	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000029794
	ENSMUSP00000029794.6
	ENSMUSP00000142808.2
GenBank Protein	Q9CQJ0	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_079692 ⟸ NM_025416

- UniProtKB:

Q9CTI2 (UniProtKB/Swiss-Prot), Q9CQJ0 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MLRTSFQGVARLVRHKALYRSPCLLPRVHLASAFGSSTESLVARFCPEKTDLKDYALPNASWCS
DMLSLYQEFLEKTKSGGWIKLPSFKSNRDHIQGLKLPFGLETASDKQDWRLFTRSIQLEGQGYE
YVIFFHPSEKKSVCLFQPGPYLEGAPGFAHGGSLAALMDETYSKTAYLAGEGLFTLSLNIKFKN
LIPVGSLAVLDIQVEKIEDQKLYMSCIAQSRDKQTVYAKSSGVFLQLQLEEQSQEQ

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RefSeq Acc Id:

ENSMUSP00000142808 ⟸ ENSMUST00000198083

RefSeq Acc Id:

ENSMUSP00000029794 ⟸ ENSMUST00000029794

Protein Domains

Thioesterase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9CQJ0-F1-model_v2	AlphaFold	Q9CQJ0	1-248	view protein structure

Promoters

RGD ID:

6881538

Promoter ID:

EPDNEW_M4194

Type:

single initiation site

Name:

Them5_1

Description:

Mus musculus thioesterase superfamily member 5 , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	3	94,343,309 - 94,343,369	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:1913448	AgrOrtholog
Ensembl Genes	ENSMUSG00000028148	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript	ENSMUST00000029794	ENTREZGENE
	ENSMUST00000029794.11	UniProtKB/Swiss-Prot
	ENSMUST00000198083.2	UniProtKB/TrEMBL
Gene3D-CATH	Hotdog Thioesterase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	HotDog_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Thioestr_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	mmu:66198	UniProtKB/Swiss-Prot
MGD	MGI:1913448	ENTREZGENE
NCBI Gene	66198	ENTREZGENE
PANTHER	ACYL-COENZYME A THIOESTERASE THEM5	UniProtKB/Swiss-Prot
	ACYL-COENZYME A THIOESTERASE THEM5	UniProtKB/Swiss-Prot
	ACYL-COENZYME A THIOESTERASE THEM5	UniProtKB/TrEMBL
	ACYL-COENZYME A THIOESTERASE THEM5	UniProtKB/TrEMBL
Pfam	4HBT	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Them5	PhenoGen
Superfamily-SCOP	SSF54637	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A0G2JEK7_MOUSE	UniProtKB/TrEMBL
	ACO15_MOUSE	UniProtKB/Swiss-Prot, ENTREZGENE
	Q9CTI2	ENTREZGENE
UniProt Secondary	Q9CTI2	UniProtKB/Swiss-Prot

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar

Mammalian Phenotype