Them5 (thioesterase superfamily member 5) - Rat Genome Database

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Gene: Them5 (thioesterase superfamily member 5) Chinchilla lanigera
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Symbol: Them5
Name: thioesterase superfamily member 5
RGD ID: 8786281
Description: ENCODES a protein that exhibits long-chain fatty acyl-CoA hydrolase activity (ortholog); INVOLVED IN cardiolipin acyl-chain remodeling (ortholog); long-chain fatty-acyl-CoA metabolic process (ortholog); ASSOCIATED WITH gastrointestinal stromal tumor (ortholog); genetic disease (ortholog); immunodeficiency 42 (ortholog); FOUND IN mitochondrial matrix (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: acyl-coenzyme A thioesterase THEM5
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955589565,182 - 574,872 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955589546,592 - 571,844 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Them5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955589565,182 - 574,872 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955589546,592 - 571,844 (+)NCBIChiLan1.0ChiLan1.0
THEM5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381151,847,101 - 151,853,712 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1151,847,101 - 151,853,712 (-)EnsemblGRCh38hg38GRCh38
GRCh371151,819,577 - 151,826,188 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361150,084,844 - 150,092,797 (-)NCBINCBI36Build 36hg18NCBI36
Celera1124,934,271 - 124,940,820 (-)NCBICelera
Cytogenetic Map1q21.3NCBI
HuRef1123,196,563 - 123,203,112 (-)NCBIHuRef
CHM1_11153,214,902 - 153,221,451 (-)NCBICHM1_1
T2T-CHM13v2.01150,970,601 - 150,977,165 (-)NCBIT2T-CHM13v2.0
Them5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39394,249,406 - 94,254,659 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl394,249,406 - 94,254,659 (+)EnsemblGRCm39 Ensembl
GRCm38394,342,099 - 94,347,352 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl394,342,099 - 94,347,352 (+)EnsemblGRCm38mm10GRCm38
MGSCv37394,146,021 - 94,151,272 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36394,427,503 - 94,432,753 (+)NCBIMGSCv36mm8
Celera395,788,493 - 95,793,740 (+)NCBICelera
Cytogenetic Map3F2.1NCBI
cM Map340.52NCBI
Them5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82184,665,335 - 184,675,041 (+)NCBIGRCr8
mRatBN7.22181,980,783 - 181,986,002 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2181,980,783 - 181,986,002 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2189,643,935 - 189,649,152 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02187,448,061 - 187,453,284 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02182,276,407 - 182,281,624 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02195,582,781 - 195,588,000 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2195,582,781 - 195,588,000 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02215,061,475 - 215,066,694 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42189,315,151 - 189,321,030 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2174,531,200 - 174,536,419 (+)NCBICelera
Cytogenetic Map2q34NCBI
THEM5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2197,967,502 - 97,977,408 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1197,718,686 - 97,735,803 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01127,205,721 - 127,212,112 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11130,849,797 - 130,856,529 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1130,849,815 - 130,856,523 (-)Ensemblpanpan1.1panPan2
THEM5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11760,857,348 - 60,865,789 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1760,857,350 - 60,865,579 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1760,301,796 - 60,310,146 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01761,876,913 - 61,885,249 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1761,876,933 - 61,885,040 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11760,703,724 - 60,712,049 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01760,789,891 - 60,798,385 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01761,519,000 - 61,527,351 (-)NCBIUU_Cfam_GSD_1.0
Them5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505823,006,213 - 23,014,051 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365802,036,704 - 2,043,897 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365802,036,595 - 2,044,053 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
THEM5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl497,332,432 - 97,359,428 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1497,319,579 - 97,358,602 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24106,343,969 - 106,383,109 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Them5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477219,523,526 - 19,530,041 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477219,523,721 - 19,530,019 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000000633   ⟹   ENSCLAP00000000602
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955589565,182 - 574,872 (+)Ensembl
RefSeq Acc Id: XM_005414538   ⟹   XP_005414595
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955589546,602 - 571,844 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005414543   ⟹   XP_005414600
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955589546,592 - 570,818 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005414545   ⟹   XP_005414602
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955589556,346 - 571,844 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013509937   ⟹   XP_013365391
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955589553,680 - 571,844 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013509938   ⟹   XP_013365392
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955589565,079 - 571,844 (+)NCBI
Sequence:
RefSeq Acc Id: XP_005414595   ⟸   XM_005414538
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_005414600   ⟸   XM_005414543
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_005414602   ⟸   XM_005414545
- Peptide Label: isoform X4
- UniProtKB: A0A8C2UK58 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013365391   ⟸   XM_013509937
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_013365392   ⟸   XM_013509938
- Peptide Label: isoform X4
- UniProtKB: A0A8C2UK58 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000000602   ⟸   ENSCLAT00000000633
Protein Domains
Thioesterase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000000481 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000000633 ENTREZGENE
  ENSCLAT00000000633.1 UniProtKB/TrEMBL
Gene3D-CATH Hotdog Thioesterase UniProtKB/TrEMBL
InterPro HotDog_dom_sf UniProtKB/TrEMBL
  Thioestr_dom UniProtKB/TrEMBL
NCBI Gene Them5 ENTREZGENE
PANTHER ACYL-COENZYME A THIOESTERASE THEM5 UniProtKB/TrEMBL
  ACYL-COENZYME A THIOESTERASE THEM5 UniProtKB/TrEMBL
Pfam 4HBT UniProtKB/TrEMBL
Superfamily-SCOP SSF54637 UniProtKB/TrEMBL
UniProt A0A8C2UK58 ENTREZGENE, UniProtKB/TrEMBL