Erich6b (glutamate rich 6B) - Rat Genome Database

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Gene: Erich6b (glutamate rich 6B) Mus musculus
Analyze
Symbol: Erich6b
Name: glutamate rich 6B
RGD ID: 1615032
MGI Page MGI
Description: Orthologous to human ERICH6B (glutamate rich 6B).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 4930564B18Rik; glutamate-rich protein 6B; glutamate-rich protein 6B-like; Gm46471; hypothetical protein LOC75272; predicted gene, 46471; uncharacterized protein LOC75272
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391475,879,662 - 75,934,165 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1475,879,689 - 75,934,157 (+)EnsemblGRCm39 Ensembl
GRCm381475,642,222 - 75,696,725 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1475,642,249 - 75,696,717 (+)EnsemblGRCm38mm10GRCm38
MGSCv371476,042,066 - 76,066,944 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361474,376,414 - 74,401,292 (+)NCBIMGSCv36mm8
Celera1473,144,181 - 73,168,998 (+)NCBICelera
Cytogenetic Map14D3NCBI
cM Map1440.28NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:16141072   PMID:16141073  


Genomics

Comparative Map Data
Erich6b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391475,879,662 - 75,934,165 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1475,879,689 - 75,934,157 (+)EnsemblGRCm39 Ensembl
GRCm381475,642,222 - 75,696,725 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1475,642,249 - 75,696,717 (+)EnsemblGRCm38mm10GRCm38
MGSCv371476,042,066 - 76,066,944 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361474,376,414 - 74,401,292 (+)NCBIMGSCv36mm8
Celera1473,144,181 - 73,168,998 (+)NCBICelera
Cytogenetic Map14D3NCBI
cM Map1440.28NCBI
ERICH6B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381345,541,294 - 45,615,739 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1345,534,522 - 45,615,739 (-)EnsemblGRCh38hg38GRCh38
GRCh371346,115,429 - 46,189,874 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361345,013,433 - 45,087,875 (-)NCBINCBI36Build 36hg18NCBI36
Celera1327,170,108 - 27,244,549 (-)NCBICelera
Cytogenetic Map13q14.13NCBI
HuRef1326,911,668 - 26,986,113 (-)NCBIHuRef
CHM1_11346,084,372 - 46,158,786 (-)NCBICHM1_1
T2T-CHM13v2.01344,762,627 - 44,837,047 (-)NCBIT2T-CHM13v2.0
Erich6b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81557,384,509 - 57,423,543 (+)NCBIGRCr8
mRatBN7.21550,979,066 - 51,014,394 (+)NCBImRatBN7.2mRatBN7.2
Rnor_6.01557,691,875 - 57,754,684 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01561,401,695 - 61,460,759 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41556,523,651 - 56,542,553 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1550,585,979 - 50,648,431 (+)NCBICelera
Cytogenetic Map15q11NCBI
Erich6b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555183,279,721 - 3,333,159 (-)NCBIChiLan1.0ChiLan1.0
ERICH6B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21445,768,880 - 45,843,314 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11336,822,921 - 36,897,573 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01327,409,374 - 27,483,814 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
ERICH6B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1225,485,832 - 5,542,217 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl225,485,891 - 5,542,216 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha225,474,925 - 5,531,318 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0225,603,799 - 5,660,025 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl225,603,858 - 5,660,024 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1225,385,612 - 5,442,002 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0225,448,778 - 5,504,943 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0225,454,151 - 5,510,550 (+)NCBIUU_Cfam_GSD_1.0
Erich6b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945155,737,589 - 155,780,600 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936857158,921 - 202,872 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ERICH6B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11121,674,478 - 21,754,947 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21122,021,206 - 22,052,091 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ERICH6B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1323,625,698 - 23,693,586 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl323,625,790 - 23,674,020 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605720,377,458 - 20,432,097 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Erich6b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247489,446,611 - 9,492,620 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Erich6b
1751 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:132
Count of miRNA genes:129
Interacting mature miRNAs:132
Transcripts:ENSMUST00000022579
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357589Kdnw2_mkidney weight 2 (mouse)Not determined1420887473121269804Mouse
27226774Tibl15_mtibia length 15, 10 week (mouse)143032195787937436Mouse
1301777Bglq15_mbody growth late QTL 15 (mouse)Not determined144296241676962593Mouse
1301424Skull21_mskull morphology 21 (mouse)Not determined144296241676962593Mouse
1300805Mors3_mmodifier of obesity related sterility 3 (mouse)Not determined144303727077037418Mouse
1301091Bbaa21_mB.burgdorferi-associated arthritis 21 (mouse)Not determined144306584777066045Mouse
4141400Nilac8_mnicotine induced locomotor activity 8 (mouse)Not determined144306584777066045Mouse
1300605El5_mepilepsy 5 (mouse)Not determined144945542583455556Mouse
4142364Pbwg18_mpostnatal body weight growth 18 (mouse)Not determined145228198486282125Mouse
1301489Lbm10_mlean body mass 10 (mouse)Not determined145376129687761529Mouse
12880432Fgf23lq3_mFGF23 serum level QTL 3 (mouse)145393744087937440Mouse
10043889Cia52_mcollagen induced arthritis QTL 52 (mouse)Not determined145608238190082509Mouse
1301562Hwq1_mheart weight quantitative locus 1 (mouse)Not determined145654674590546941Mouse
1357565wrmod1_mwobbler modifier 1 (mouse)Not determined1458179640101859473Mouse
11039527Ccc2_mcolitis susceptibility in the Collaborative Cross 2 (mouse)145991861294138217Mouse
1300666Fembm2_mfemoral bone morphometry 2 (mouse)Not determined146239746096397680Mouse
14747006Mancz12_mmandible centroid size 12 (mouse)1470071977104071977Mouse
10054475Ossc3_mosteosarcoma susceptibility 3 (mouse)Not determined1470863768104863926Mouse
1300551Lprm3_mlymphoproliferation modifier 3 (mouse)Not determined1471221224105221344Mouse
1301844Pgia29_mproteoglycan induced arthritis 29 (mouse)Not determined1474352296108352384Mouse
1558819Ossc2_mosteosarcoma susceptibility 2 (mouse)Not determined1474394976108395093Mouse


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000022579   ⟹   ENSMUSP00000022579
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1475,879,699 - 75,904,577 (+)Ensembl
GRCm38.p6 Ensembl1475,642,259 - 75,667,137 (+)Ensembl
RefSeq Acc Id: ENSMUST00000238633   ⟹   ENSMUSP00000158673
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1475,879,689 - 75,934,157 (+)Ensembl
GRCm38.p6 Ensembl1475,642,249 - 75,696,717 (+)Ensembl
RefSeq Acc Id: NM_001369022   ⟹   NP_001355951
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391475,879,662 - 75,934,165 (+)NCBI
GRCm381475,642,222 - 75,696,725 (+)NCBI
Sequence:
RefSeq Acc Id: NM_029230   ⟹   NP_083506
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391475,879,699 - 75,904,577 (+)NCBI
GRCm381475,642,259 - 75,667,137 (+)NCBI
Celera1473,144,181 - 73,168,998 (+)ENTREZGENE
cM Map14 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_001355951 (Get FASTA)   NCBI Sequence Viewer  
  NP_083506 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAB30152 (Get FASTA)   NCBI Sequence Viewer  
  EDL35827 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000022579
  ENSMUSP00000022579.2
  ENSMUSP00000158673
  ENSMUSP00000158673.2
Reference Protein Sequences
RefSeq Acc Id: NP_083506   ⟸   NM_029230
- Peptide Label: isoform 2
- UniProtKB: Q9D4S6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001355951   ⟸   NM_001369022
- Peptide Label: isoform 1
- UniProtKB: A0A571BEV3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSMUSP00000158673   ⟸   ENSMUST00000238633
RefSeq Acc Id: ENSMUSP00000022579   ⟸   ENSMUST00000022579
Protein Domains
FAM194 C-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A571BEV3-F1-model_v2 AlphaFold A0A571BEV3 1-574 view protein structure

Promoters
RGD ID:8683004
Promoter ID:EPDNEW_M19533
Type:initiation region
Name:Erich6b_1
Description:Mus musculus glutamate rich 6B , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381475,642,263 - 75,642,323EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1922522 AgrOrtholog
Ensembl Genes ENSMUSG00000022002 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000022579 ENTREZGENE
  ENSMUST00000022579.2 UniProtKB/TrEMBL
  ENSMUST00000238633 ENTREZGENE
  ENSMUST00000238633.2 UniProtKB/TrEMBL
InterPro FAM194_C UniProtKB/TrEMBL
MGD MGI:1922522 ENTREZGENE
NCBI Gene 75272 ENTREZGENE
PANTHER GLUTAMATE-RICH PROTEIN 6B UniProtKB/TrEMBL
  SIMILAR TO CHROMOSOME 3 OPEN READING FRAME 20 UniProtKB/TrEMBL
Pfam FAM194 UniProtKB/TrEMBL
PhenoGen Erich6b PhenoGen
UniProt A0A571BEV3 ENTREZGENE, UniProtKB/TrEMBL
  Q9D4S6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-03-14 Erich6b  glutamate rich 6B  Gm46471  predicted gene, 46471  Data merged from RGD:12793797 737654 PROVISIONAL
2015-08-04 Erich6b  glutamate rich 6B  4930564B18Rik  RIKEN cDNA 4930564B18 gene  Symbol and/or name change 5135510 APPROVED