Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | ISO | Mfsd3 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of MFSD3 mRNA] | CTD | PMID:31150632 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Mfsd3 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of MFSD3 mRNA | CTD | PMID:21215274 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Mfsd3 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of MFSD3 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of MFSD3 mRNA | CTD | PMID:21570461 | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | Mfsd3 (Rattus norvegicus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of MFSD3 mRNA | CTD | PMID:30071829 | 4,4'-sulfonyldiphenol | multiple interactions | ISO | Mfsd3 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of MFSD3 mRNA | CTD | PMID:36041667 | acrylamide | decreases expression | ISO | MFSD3 (Homo sapiens) | 6480464 | Acrylamide results in decreased expression of MFSD3 mRNA | CTD | PMID:32763439 | aflatoxin B1 | affects expression | ISO | MFSD3 (Homo sapiens) | 6480464 | Aflatoxin B1 affects the expression of MFSD3 protein | CTD | PMID:20106945 | aflatoxin B1 | decreases expression | ISO | MFSD3 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased expression of MFSD3 mRNA | CTD | PMID:27153756 | aldehydo-D-glucose | multiple interactions | EXP | | 6480464 | fucoxanthin inhibits the reaction [Glucose results in increased expression of MFSD3 mRNA] | CTD | PMID:33448797 | aldehydo-D-glucose | increases expression | EXP | | 6480464 | Glucose results in increased expression of MFSD3 mRNA | CTD | PMID:33448797 | aristolochic acid A | decreases expression | ISO | MFSD3 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of MFSD3 mRNA | CTD | PMID:33212167 | benzo[a]pyrene | decreases expression | ISO | MFSD3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of MFSD3 mRNA | CTD | PMID:20106945 and PMID:32234424 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of MFSD3 mRNA | CTD | PMID:22228805 | bisphenol A | multiple interactions | ISO | Mfsd3 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of MFSD3 mRNA and [bisphenol A co-treated with Testosterone] results in increased expression of MFSD3 mRNA | CTD | PMID:26496021 and PMID:36041667 | bisphenol A | decreases expression | ISO | Mfsd3 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of MFSD3 mRNA | CTD | PMID:30816183 more ... | bisphenol A | increases expression | ISO | Mfsd3 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of MFSD3 mRNA | CTD | PMID:25181051 | bisphenol F | multiple interactions | ISO | Mfsd3 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of MFSD3 mRNA | CTD | PMID:36041667 | carbon nanotube | decreases expression | EXP | | 6480464 | Nanotubes and Carbon results in decreased expression of MFSD3 mRNA | CTD | PMID:25620056 | cisplatin | multiple interactions | ISO | MFSD3 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of MFSD3 mRNA | CTD | PMID:27392435 | cobalt dichloride | decreases expression | ISO | MFSD3 (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of MFSD3 mRNA | CTD | PMID:19320972 | copper atom | multiple interactions | ISO | MFSD3 (Homo sapiens) | 6480464 | [Disulfiram binds to Copper] which results in increased expression of MFSD3 mRNA and [NSC 689534 binds to Copper] which results in decreased expression of MFSD3 mRNA | CTD | PMID:20971185 and PMID:24690739 | copper(0) | multiple interactions | ISO | MFSD3 (Homo sapiens) | 6480464 | [Disulfiram binds to Copper] which results in increased expression of MFSD3 mRNA and [NSC 689534 binds to Copper] which results in decreased expression of MFSD3 mRNA | CTD | PMID:20971185 and PMID:24690739 | cyclosporin A | decreases expression | ISO | MFSD3 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of MFSD3 mRNA | CTD | PMID:20106945 and PMID:25562108 | cyclosporin A | decreases methylation | ISO | MFSD3 (Homo sapiens) | 6480464 | Cyclosporine results in decreased methylation of MFSD3 promoter | CTD | PMID:27989131 | D-glucose | multiple interactions | EXP | | 6480464 | fucoxanthin inhibits the reaction [Glucose results in increased expression of MFSD3 mRNA] | CTD | PMID:33448797 | D-glucose | increases expression | EXP | | 6480464 | Glucose results in increased expression of MFSD3 mRNA | CTD | PMID:33448797 | disulfiram | multiple interactions | ISO | MFSD3 (Homo sapiens) | 6480464 | [Disulfiram binds to Copper] which results in increased expression of MFSD3 mRNA | CTD | PMID:24690739 | dorsomorphin | multiple interactions | ISO | MFSD3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MFSD3 mRNA | CTD | PMID:27188386 | epoxiconazole | decreases expression | EXP | | 6480464 | epoxiconazole results in decreased expression of MFSD3 mRNA | CTD | PMID:35436446 | ethyl methanesulfonate | decreases expression | ISO | MFSD3 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in decreased expression of MFSD3 mRNA | CTD | PMID:23649840 | fenthion | increases expression | EXP | | 6480464 | Fenthion results in increased expression of MFSD3 mRNA | CTD | PMID:34813904 | formaldehyde | decreases expression | ISO | MFSD3 (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of MFSD3 mRNA | CTD | PMID:23649840 | fucoxanthin | multiple interactions | EXP | | 6480464 | fucoxanthin inhibits the reaction [Glucose results in increased expression of MFSD3 mRNA] | CTD | PMID:33448797 | gentamycin | decreases expression | ISO | Mfsd3 (Rattus norvegicus) | 6480464 | Gentamicins results in decreased expression of MFSD3 mRNA | CTD | PMID:33387578 | glucose | multiple interactions | EXP | | 6480464 | fucoxanthin inhibits the reaction [Glucose results in increased expression of MFSD3 mRNA] | CTD | PMID:33448797 | glucose | increases expression | EXP | | 6480464 | Glucose results in increased expression of MFSD3 mRNA | CTD | PMID:33448797 | inulin | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of MFSD3 mRNA | CTD | PMID:36331819 | iron dichloride | decreases expression | ISO | MFSD3 (Homo sapiens) | 6480464 | ferrous chloride results in decreased expression of MFSD3 mRNA | CTD | PMID:35984750 | isobutanol | multiple interactions | ISO | MFSD3 (Homo sapiens) | 6480464 | [[Gasoline co-treated with isobutyl alcohol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of MFSD3 mRNA | CTD | PMID:29432896 | methyl methanesulfonate | decreases expression | ISO | MFSD3 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of MFSD3 mRNA | CTD | PMID:23649840 | N-ethyl-N-nitrosourea | increases mutagenesis | EXP | | 6480464 | Ethylnitrosourea results in increased mutagenesis of MFSD3 gene | CTD | PMID:27776689 | paracetamol | decreases expression | ISO | Mfsd3 (Rattus norvegicus) | 6480464 | Acetaminophen results in decreased expression of MFSD3 mRNA | CTD | PMID:33387578 | perfluorooctane-1-sulfonic acid | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of MFSD3 mRNA | CTD | PMID:36331819 | SB 431542 | multiple interactions | ISO | MFSD3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MFSD3 mRNA | CTD | PMID:27188386 | silver atom | decreases expression | EXP | | 6480464 | Silver results in decreased expression of MFSD3 mRNA | CTD | PMID:27131904 | silver(0) | decreases expression | EXP | | 6480464 | Silver results in decreased expression of MFSD3 mRNA | CTD | PMID:27131904 | Soman | decreases expression | ISO | Mfsd3 (Rattus norvegicus) | 6480464 | Soman results in decreased expression of MFSD3 mRNA | CTD | PMID:19281266 | sunitinib | increases expression | ISO | MFSD3 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of MFSD3 mRNA | CTD | PMID:31533062 | temozolomide | increases expression | ISO | MFSD3 (Homo sapiens) | 6480464 | Temozolomide results in increased expression of MFSD3 mRNA | CTD | PMID:31758290 | testosterone | multiple interactions | ISO | Mfsd3 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with Testosterone] results in increased expression of MFSD3 mRNA | CTD | PMID:26496021 | tetrachloroethene | decreases expression | EXP | | 6480464 | Tetrachloroethylene results in decreased expression of MFSD3 mRNA | CTD | PMID:28973375 | tetrachloromethane | decreases expression | ISO | Mfsd3 (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in decreased expression of MFSD3 mRNA | CTD | PMID:31150632 | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of MFSD3 mRNA | CTD | PMID:31919559 | tetrachloromethane | multiple interactions | ISO | Mfsd3 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of MFSD3 mRNA] | CTD | PMID:31150632 | thioacetamide | decreases expression | ISO | Mfsd3 (Rattus norvegicus) | 6480464 | Thioacetamide results in decreased expression of MFSD3 mRNA | CTD | PMID:34492290 | trichloroethene | increases expression | ISO | Mfsd3 (Rattus norvegicus) | 6480464 | Trichloroethylene results in increased expression of MFSD3 mRNA | CTD | PMID:33387578 | trovafloxacin | decreases expression | EXP | | 6480464 | trovafloxacin results in decreased expression of MFSD3 mRNA | CTD | PMID:35537566 | valproic acid | increases methylation | ISO | MFSD3 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of MFSD3 gene | CTD | PMID:29154799 | valproic acid | multiple interactions | ISO | MFSD3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MFSD3 mRNA | CTD | PMID:27188386 | valproic acid | increases expression | ISO | MFSD3 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of MFSD3 mRNA | CTD | PMID:23179753 more ... | valproic acid | affects expression | ISO | MFSD3 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of MFSD3 mRNA | CTD | PMID:25979313 | vinclozolin | decreases expression | ISO | Mfsd3 (Rattus norvegicus) | 6480464 | vinclozolin results in decreased expression of MFSD3 mRNA | CTD | PMID:23034163 | |