Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 17beta-estradiol | increases expression | ISO | MFNG (Homo sapiens) | 6480464 | Estradiol results in increased expression of MFNG mRNA | CTD | PMID:23019147 | 17beta-estradiol | decreases expression | EXP | | 6480464 | Estradiol results in decreased expression of MFNG mRNA | CTD | PMID:19484750 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Mfng (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of MFNG mRNA | CTD | PMID:34747641 | 4,4'-diaminodiphenylmethane | decreases expression | EXP | | 6480464 | 4 and 4'-diaminodiphenylmethane results in decreased expression of MFNG mRNA | CTD | PMID:18648102 | 4-hydroxyphenyl retinamide | decreases expression | EXP | | 6480464 | Fenretinide results in decreased expression of MFNG mRNA | CTD | PMID:28973697 | 5-aza-2'-deoxycytidine | affects expression | ISO | MFNG (Homo sapiens) | 6480464 | Decitabine affects the expression of MFNG mRNA | CTD | PMID:23300844 | 6-propyl-2-thiouracil | increases expression | ISO | Mfng (Rattus norvegicus) | 6480464 | Propylthiouracil results in increased expression of MFNG mRNA | CTD | PMID:24780913 | acrylamide | decreases expression | ISO | MFNG (Homo sapiens) | 6480464 | Acrylamide results in decreased expression of MFNG mRNA | CTD | PMID:32763439 | all-trans-retinoic acid | decreases expression | ISO | MFNG (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of MFNG mRNA | CTD | PMID:23724009 | alpha-Zearalanol | increases expression | ISO | Mfng (Rattus norvegicus) | 6480464 | Zeranol results in increased expression of MFNG mRNA | CTD | PMID:35163327 | alpha-Zearalanol | multiple interactions | ISO | Mfng (Rattus norvegicus) | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in increased expression of MFNG mRNA | CTD | PMID:35163327 | aristolochic acid A | increases expression | ISO | MFNG (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of MFNG mRNA | CTD | PMID:33212167 | belinostat | decreases expression | ISO | MFNG (Homo sapiens) | 6480464 | belinostat results in decreased expression of MFNG mRNA | CTD | PMID:26272509 | belinostat | multiple interactions | ISO | MFNG (Homo sapiens) | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MFNG mRNA | CTD | PMID:27188386 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of MFNG mRNA | CTD | PMID:22228805 | benzo[a]pyrene | affects methylation | ISO | MFNG (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of MFNG 3' UTR and Benzo(a)pyrene affects the methylation of MFNG intron | CTD | PMID:27901495 and PMID:30157460 | benzo[a]pyrene | increases methylation | ISO | MFNG (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of MFNG exon and Benzo(a)pyrene results in increased methylation of MFNG promoter | CTD | PMID:27901495 | benzo[b]fluoranthene | increases expression | EXP | | 6480464 | benzo(b)fluoranthene results in increased expression of MFNG mRNA | CTD | PMID:26377693 | bis(2-ethylhexyl) phthalate | decreases expression | ISO | MFNG (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in decreased expression of MFNG mRNA | CTD | PMID:31163220 | bisphenol A | decreases expression | ISO | MFNG (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of MFNG mRNA | CTD | PMID:31715268 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of MFNG mRNA | CTD | PMID:32156529 | bisphenol A | increases methylation | ISO | Mfng (Rattus norvegicus) | 6480464 | bisphenol A results in increased methylation of MFNG gene | CTD | PMID:28505145 | bisphenol A | affects expression | ISO | Mfng (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of MFNG mRNA | CTD | PMID:25181051 | bortezomib | decreases expression | ISO | MFNG (Homo sapiens) | 6480464 | Bortezomib results in decreased expression of MFNG mRNA | CTD | PMID:20977926 | chlorpyrifos | increases expression | EXP | | 6480464 | Chlorpyrifos results in increased expression of MFNG mRNA | CTD | PMID:37019170 | cisplatin | affects expression | ISO | MFNG (Homo sapiens) | 6480464 | Cisplatin affects the expression of MFNG mRNA | CTD | PMID:23300844 | cisplatin | increases expression | ISO | MFNG (Homo sapiens) | 6480464 | Cisplatin results in increased expression of MFNG mRNA | CTD | PMID:27392435 | Cuprizon | increases expression | ISO | Mfng (Rattus norvegicus) | 6480464 | Cuprizone results in increased expression of MFNG mRNA | CTD | PMID:27523638 | curcumin | increases expression | ISO | MFNG (Homo sapiens) | 6480464 | Curcumin results in increased expression of MFNG mRNA | CTD | PMID:17198877 | cyclosporin A | decreases expression | ISO | MFNG (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of MFNG mRNA | CTD | PMID:20106945 | disodium selenite | increases expression | ISO | MFNG (Homo sapiens) | 6480464 | Sodium Selenite results in increased expression of MFNG mRNA | CTD | PMID:18175754 | dorsomorphin | multiple interactions | ISO | MFNG (Homo sapiens) | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | formaldehyde | decreases expression | ISO | MFNG (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of MFNG mRNA | CTD | PMID:23649840 | furan | increases expression | ISO | Mfng (Rattus norvegicus) | 6480464 | furan results in increased expression of MFNG mRNA | CTD | PMID:27387713 | genistein | increases expression | ISO | MFNG (Homo sapiens) | 6480464 | Genistein results in increased expression of MFNG mRNA | CTD | PMID:23019147 | gentamycin | increases expression | ISO | Mfng (Rattus norvegicus) | 6480464 | Gentamicins results in increased expression of MFNG mRNA | CTD | PMID:22061828 | graphite | affects expression | ISO | Mfng (Rattus norvegicus) | 6480464 | Graphite affects the expression of MFNG mRNA | CTD | PMID:29933104 | mercury dibromide | decreases expression | ISO | MFNG (Homo sapiens) | 6480464 | mercuric bromide results in decreased expression of MFNG mRNA | CTD | PMID:26272509 | mercury dibromide | multiple interactions | ISO | MFNG (Homo sapiens) | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MFNG mRNA | CTD | PMID:27188386 | methyl methanesulfonate | decreases expression | ISO | MFNG (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of MFNG mRNA | CTD | PMID:23649840 | methylmercury chloride | decreases expression | ISO | MFNG (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of MFNG mRNA | CTD | PMID:28001369 | N-methyl-4-phenylpyridinium | increases expression | ISO | MFNG (Homo sapiens) | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of MFNG mRNA | CTD | PMID:24810058 | nickel atom | increases expression | ISO | MFNG (Homo sapiens) | 6480464 | Nickel results in increased expression of MFNG mRNA | CTD | PMID:24768652 and PMID:25583101 | ozone | multiple interactions | EXP | | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of MFNG mRNA | CTD | PMID:34911549 | p-chloromercuribenzoic acid | decreases expression | ISO | MFNG (Homo sapiens) | 6480464 | p-Chloromercuribenzoic Acid results in decreased expression of MFNG mRNA | CTD | PMID:26272509 | p-chloromercuribenzoic acid | multiple interactions | ISO | MFNG (Homo sapiens) | 6480464 | [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MFNG mRNA | CTD | PMID:27188386 | panobinostat | multiple interactions | ISO | MFNG (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MFNG mRNA | CTD | PMID:27188386 | panobinostat | decreases expression | ISO | MFNG (Homo sapiens) | 6480464 | panobinostat results in decreased expression of MFNG mRNA | CTD | PMID:26272509 | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of MFNG mRNA | CTD | PMID:17562736 | paracetamol | decreases expression | ISO | Mfng (Rattus norvegicus) | 6480464 | Acetaminophen results in decreased expression of MFNG mRNA | CTD | PMID:33387578 | perfluorooctanoic acid | multiple interactions | ISO | Mfng (Rattus norvegicus) | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in increased expression of MFNG mRNA | CTD | PMID:35163327 | phenylmercury acetate | decreases expression | ISO | MFNG (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in decreased expression of MFNG mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | ISO | MFNG (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MFNG mRNA | CTD | PMID:27188386 | pirinixic acid | multiple interactions | ISO | MFNG (Homo sapiens) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of MFNG mRNA | CTD | PMID:19710929 | pirinixic acid | decreases expression | EXP | | 6480464 | pirinixic acid results in decreased expression of MFNG mRNA | CTD | PMID:20813756 | progesterone | increases expression | ISO | MFNG (Homo sapiens) | 6480464 | Progesterone results in increased expression of MFNG mRNA | CTD | PMID:21540246 | rotenone | increases expression | ISO | MFNG (Homo sapiens) | 6480464 | Rotenone results in increased expression of MFNG mRNA | CTD | PMID:29955902 | SB 431542 | multiple interactions | ISO | MFNG (Homo sapiens) | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | silicon dioxide | increases expression | ISO | MFNG (Homo sapiens) | 6480464 | Silicon Dioxide results in increased expression of MFNG mRNA | CTD | PMID:25351596 | sodium arsenite | affects methylation | ISO | MFNG (Homo sapiens) | 6480464 | sodium arsenite affects the methylation of MFNG gene | CTD | PMID:28589171 | trichloroethene | increases expression | ISO | Mfng (Rattus norvegicus) | 6480464 | Trichloroethylene results in increased expression of MFNG mRNA | CTD | PMID:33387578 | trichostatin A | decreases expression | ISO | MFNG (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of MFNG mRNA | CTD | PMID:24935251 and PMID:26272509 | trichostatin A | multiple interactions | ISO | MFNG (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MFNG mRNA | CTD | PMID:27188386 | tris(2-butoxyethyl) phosphate | affects expression | ISO | MFNG (Homo sapiens) | 6480464 | tris(2-butoxyethyl) phosphate affects the expression of MFNG mRNA | CTD | PMID:29024780 | valproic acid | affects expression | ISO | MFNG (Homo sapiens) | 6480464 | Valproic Acid affects the expression of MFNG mRNA | CTD | PMID:25979313 | valproic acid | multiple interactions | ISO | MFNG (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MFNG mRNA | CTD | PMID:27188386 | valproic acid | decreases expression | ISO | MFNG (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of MFNG mRNA | CTD | PMID:23179753 more ... | venlafaxine hydrochloride | decreases expression | ISO | Mfng (Rattus norvegicus) | 6480464 | Venlafaxine Hydrochloride results in decreased expression of MFNG mRNA | CTD | PMID:25423262 | vinclozolin | decreases methylation | ISO | Mfng (Rattus norvegicus) | 6480464 | vinclozolin results in decreased methylation of MFNG gene | CTD | PMID:31079544 | |