ALCAM (activated leukocyte cell adhesion molecule) - Rat Genome Database

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Gene: ALCAM (activated leukocyte cell adhesion molecule) Sus scrofa
Analyze
Symbol: ALCAM
Name: activated leukocyte cell adhesion molecule
RGD ID: 14288641
Description: ENCODES a protein that exhibits identical protein binding (inferred); INVOLVED IN axon guidance (ortholog); motor neuron axon guidance (ortholog); ASSOCIATED WITH Animal Mammary Neoplasms (ortholog); carcinoma (ortholog); COVID-19 (ortholog); FOUND IN T cell receptor complex (ortholog); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: CD166 antigen
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13153,794,993 - 153,998,208 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113153,794,991 - 153,998,241 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213162,988,454 - 163,045,771 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21560815   PMID:30032202  


Genomics

Comparative Map Data
ALCAM
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13153,794,993 - 153,998,208 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113153,794,991 - 153,998,241 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213162,988,454 - 163,045,771 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ALCAM
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383105,366,909 - 105,576,900 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3105,366,909 - 105,576,900 (+)EnsemblGRCh38hg38GRCh38
GRCh373105,085,753 - 105,295,744 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363106,568,403 - 106,778,434 (+)NCBINCBI36Build 36hg18NCBI36
Build 343106,568,879 - 106,776,709NCBI
Celera3103,484,109 - 103,694,111 (+)NCBICelera
Cytogenetic Map3q13.11NCBI
HuRef3102,460,407 - 102,670,632 (+)NCBIHuRef
CHM1_13105,048,389 - 105,258,778 (+)NCBICHM1_1
T2T-CHM13v2.03108,084,937 - 108,294,916 (+)NCBIT2T-CHM13v2.0
Alcam
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391652,069,359 - 52,273,444 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1652,069,359 - 52,274,437 (-)EnsemblGRCm39 Ensembl
GRCm381652,248,996 - 52,453,081 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1652,248,996 - 52,454,074 (-)EnsemblGRCm38mm10GRCm38
MGSCv371652,249,109 - 52,453,110 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361652,170,261 - 52,373,422 (-)NCBIMGSCv36mm8
Celera1652,580,657 - 52,784,804 (-)NCBICelera
Cytogenetic Map16B5NCBI
cM Map1632.88NCBI
Alcam
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81161,804,932 - 62,005,250 (+)NCBIGRCr8
mRatBN7.21148,336,123 - 48,536,296 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1148,336,169 - 48,537,954 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1157,110,123 - 57,309,926 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01149,771,802 - 49,971,585 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01148,895,907 - 49,095,677 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01150,780,735 - 50,985,083 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1150,781,127 - 50,985,083 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01153,964,563 - 54,165,636 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41149,424,243 - 49,630,071 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11149,481,831 - 49,687,660 (+)NCBI
Celera1148,024,575 - 48,218,199 (+)NCBICelera
Cytogenetic Map11q21NCBI
Alcam
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554276,494,124 - 6,545,963 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554276,494,657 - 6,544,668 (+)NCBIChiLan1.0ChiLan1.0
ALCAM
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22103,319,297 - 103,529,920 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13103,325,067 - 103,534,696 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03102,468,354 - 102,677,932 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13109,407,296 - 109,616,518 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3109,407,992 - 109,616,518 (+)Ensemblpanpan1.1panPan2
ALCAM
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13310,983,363 - 11,195,170 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3310,983,363 - 11,370,085 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3311,088,414 - 11,300,048 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03311,141,772 - 11,353,405 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3311,141,772 - 11,353,405 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13311,011,197 - 11,222,028 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03311,078,031 - 11,289,490 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03311,486,320 - 11,697,980 (+)NCBIUU_Cfam_GSD_1.0
Alcam
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602145,582,988 - 145,771,697 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936701895,376 - 1,084,172 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936701895,414 - 1,084,155 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ALCAM
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12275,261,104 - 75,475,201 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2275,260,970 - 75,321,082 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604191,034,797 - 91,244,770 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Alcam
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473144,091,769 - 44,280,621 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473144,092,505 - 44,280,022 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ALCAM
4686 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 8 4 3 4 22 2 2 3
Low 2 1 2 1 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000013072   ⟹   ENSSSCP00000012727
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl13153,794,995 - 153,998,208 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000032688   ⟹   ENSSSCP00000030207
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl13153,794,993 - 153,998,196 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000034028   ⟹   ENSSSCP00000028677
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl13153,794,995 - 153,997,989 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000043034   ⟹   ENSSSCP00000047159
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl13153,794,991 - 153,998,022 (-)Ensembl
RefSeq Acc Id: XM_003358827   ⟹   XP_003358875
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.113153,794,991 - 153,998,240 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013982482   ⟹   XP_013837936
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.113153,794,991 - 153,998,241 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021070497   ⟹   XP_020926156
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.113153,794,991 - 153,998,240 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021070498   ⟹   XP_020926157
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.113153,794,991 - 153,998,240 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_013837936   ⟸   XM_013982482
- Peptide Label: isoform X2
- UniProtKB: A0A8D1UMV5 (UniProtKB/TrEMBL),   K9IWH1 (UniProtKB/TrEMBL),   K7GLE8 (UniProtKB/TrEMBL),   K7GQN5 (UniProtKB/TrEMBL),   A0A8D1U7Q4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003358875   ⟸   XM_003358827
- Peptide Label: isoform X1
- UniProtKB: A0A4X1SHK9 (UniProtKB/TrEMBL),   A0A5K1UB62 (UniProtKB/TrEMBL),   A0A8D1U7Q4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020926156   ⟸   XM_021070497
- Peptide Label: isoform X1
- UniProtKB: A0A4X1SHK9 (UniProtKB/TrEMBL),   A0A5K1UB62 (UniProtKB/TrEMBL),   A0A8D1U7Q4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020926157   ⟸   XM_021070498
- Peptide Label: isoform X1
- UniProtKB: A0A4X1SHK9 (UniProtKB/TrEMBL),   A0A5K1UB62 (UniProtKB/TrEMBL),   A0A8D1U7Q4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000028677   ⟸   ENSSSCT00000034028
RefSeq Acc Id: ENSSSCP00000012727   ⟸   ENSSSCT00000013072
RefSeq Acc Id: ENSSSCP00000030207   ⟸   ENSSSCT00000032688
RefSeq Acc Id: ENSSSCP00000047159   ⟸   ENSSSCT00000043034
Protein Domains
Ig-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000011946 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015045561 UniProtKB/TrEMBL
  ENSSSCG00030058932 UniProtKB/TrEMBL
  ENSSSCG00055020900 UniProtKB/TrEMBL
  ENSSSCG00060020300 UniProtKB/TrEMBL
  ENSSSCG00065011046 UniProtKB/TrEMBL
  ENSSSCG00070001080 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000013072 ENTREZGENE
  ENSSSCT00000013072.6 UniProtKB/TrEMBL
  ENSSSCT00000032688 ENTREZGENE
  ENSSSCT00000032688.4 UniProtKB/TrEMBL
  ENSSSCT00000034028 ENTREZGENE
  ENSSSCT00000034028.4 UniProtKB/TrEMBL
  ENSSSCT00015061540.1 UniProtKB/TrEMBL
  ENSSSCT00015061716.1 UniProtKB/TrEMBL
  ENSSSCT00030082399.1 UniProtKB/TrEMBL
  ENSSSCT00030082423.1 UniProtKB/TrEMBL
  ENSSSCT00055041622.1 UniProtKB/TrEMBL
  ENSSSCT00055041775.1 UniProtKB/TrEMBL
  ENSSSCT00060027474.1 UniProtKB/TrEMBL
  ENSSSCT00060027506.1 UniProtKB/TrEMBL
  ENSSSCT00065014687.1 UniProtKB/TrEMBL
  ENSSSCT00065014717.1 UniProtKB/TrEMBL
  ENSSSCT00070002102.1 UniProtKB/TrEMBL
  ENSSSCT00070002109.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro CD80_C2-set UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
KEGG Report ssc:397269 UniProtKB/TrEMBL
NCBI Gene ALCAM ENTREZGENE
PANTHER CELL SURFACE GLYCOPROTEIN MUC18-RELATED UniProtKB/TrEMBL
  PTHR11973:SF2 UniProtKB/TrEMBL
Pfam C2-set_2 UniProtKB/TrEMBL
  Ig_2 UniProtKB/TrEMBL
  Ig_3 UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
SMART SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
UniProt A0A4X1SHK3_PIG UniProtKB/TrEMBL
  A0A4X1SHK9 ENTREZGENE, UniProtKB/TrEMBL
  A0A5K1UB60_PIG UniProtKB/TrEMBL
  A0A5K1UB62 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1U7Q4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1UMV5 ENTREZGENE, UniProtKB/TrEMBL
  F1SL34_PIG UniProtKB/TrEMBL
  K7GLE8 ENTREZGENE, UniProtKB/TrEMBL
  K7GQN5 ENTREZGENE
  K9IWH1 ENTREZGENE
  Q9BDE7_PIG UniProtKB/TrEMBL
UniProt Secondary K7GQN5 UniProtKB/TrEMBL
  K9IWH1 UniProtKB/TrEMBL
VGNC ID VGNC:85236 ENTREZGENE