TRPV5 (transient receptor potential cation channel subfamily V member 5) - Rat Genome Database

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Gene: TRPV5 (transient receptor potential cation channel subfamily V member 5) Sus scrofa
Analyze
Symbol: TRPV5
Name: transient receptor potential cation channel subfamily V member 5
RGD ID: 14157647
Description: ENCODES a protein that exhibits calcium channel activity (ortholog); INVOLVED IN calcium ion transport into cytosol (ortholog); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; ASSOCIATED WITH genetic disease (ortholog); gestational diabetes (ortholog); pre-eclampsia (ortholog); FOUND IN apical plasma membrane (ortholog); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl187,284,589 - 7,318,392 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1187,285,186 - 7,341,965 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2187,540,598 - 7,549,310 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
TRPV5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl187,284,589 - 7,318,392 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1187,285,186 - 7,341,965 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2187,540,598 - 7,549,310 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TRPV5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387142,908,101 - 142,933,746 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7142,908,101 - 142,933,746 (-)EnsemblGRCh38hg38GRCh38
GRCh377142,605,267 - 142,630,843 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367142,315,770 - 142,340,942 (-)NCBINCBI36Build 36hg18NCBI36
Build 347142,122,103 - 142,147,742NCBI
Celera7137,442,506 - 137,467,678 (-)NCBICelera
Cytogenetic Map7q34NCBI
HuRef7136,943,932 - 136,969,107 (-)NCBIHuRef
CHM1_17142,542,454 - 142,567,695 (-)NCBICHM1_1
T2T-CHM13v2.07144,263,556 - 144,289,165 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27142,007,517 - 142,032,689 (-)NCBI

Variants

.
Variants in TRPV5
2224 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 2
Low 6 2 4 1 2 2 1
Below cutoff 2 2 1 2 16 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000017933   ⟹   ENSSSCP00000017452
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl187,332,491 - 7,348,381 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000057027   ⟹   ENSSSCP00000035081
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl187,332,222 - 7,348,379 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000076572   ⟹   ENSSSCP00000063408
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl187,284,589 - 7,318,392 (+)Ensembl
RefSeq Acc Id: XM_003360094   ⟹   XP_003360142
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1187,285,188 - 7,318,395 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021078896   ⟹   XP_020934555
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1187,285,186 - 7,318,395 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021078897   ⟹   XP_020934556
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1187,288,639 - 7,318,395 (+)NCBI
Sequence:
RefSeq Acc Id: XR_002340352
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1187,285,186 - 7,341,965 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020934555   ⟸   XM_021078896
- Peptide Label: isoform X1
- UniProtKB: A0A480QGB9 (UniProtKB/TrEMBL),   A0A8D1G440 (UniProtKB/TrEMBL),   A0A8D0SWK0 (UniProtKB/TrEMBL),   A0A8D0MU24 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003360142   ⟸   XM_003360094
- Peptide Label: isoform X1
- UniProtKB: A0A480QGB9 (UniProtKB/TrEMBL),   A0A8D1G440 (UniProtKB/TrEMBL),   A0A8D0SWK0 (UniProtKB/TrEMBL),   A0A8D0MU24 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020934556   ⟸   XM_021078897
- Peptide Label: isoform X2
- UniProtKB: A0A8D0SWK0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000063408   ⟸   ENSSSCT00000076572
RefSeq Acc Id: ENSSSCP00000035081   ⟸   ENSSSCT00000057027
RefSeq Acc Id: ENSSSCP00000017452   ⟸   ENSSSCT00000017933
Protein Domains
Ion transport


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000016469 Ensembl, UniProtKB/TrEMBL
  ENSSSCG00000062134 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005040342 UniProtKB/TrEMBL
  ENSSSCG00015016301 UniProtKB/TrEMBL
  ENSSSCG00025060239 UniProtKB/TrEMBL
  ENSSSCG00030041830 UniProtKB/TrEMBL
  ENSSSCG00040071039 UniProtKB/TrEMBL
  ENSSSCG00045011511 UniProtKB/TrEMBL
  ENSSSCG00065067234 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000017933.4 UniProtKB/TrEMBL
  ENSSSCT00000057027.2 UniProtKB/TrEMBL
  ENSSSCT00000076572 ENTREZGENE
  ENSSSCT00000076572.2 UniProtKB/TrEMBL
  ENSSSCT00005064774.1 UniProtKB/TrEMBL
  ENSSSCT00015021889.1 UniProtKB/TrEMBL
  ENSSSCT00025085738.1 UniProtKB/TrEMBL
  ENSSSCT00030058222.1 UniProtKB/TrEMBL
  ENSSSCT00040097745.1 UniProtKB/TrEMBL
  ENSSSCT00045019948.1 UniProtKB/TrEMBL
  ENSSSCT00065092437.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.20 UniProtKB/TrEMBL
InterPro Ankyrin_rpt UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/TrEMBL
  Ion_trans_dom UniProtKB/TrEMBL
  TRPV UniProtKB/TrEMBL
  TRPV5 UniProtKB/TrEMBL
  TRPV5/TRPV6 UniProtKB/TrEMBL
  TRPV6_channel UniProtKB/TrEMBL
NCBI Gene TRPV5 ENTREZGENE
PANTHER PTHR10582 UniProtKB/TrEMBL
  TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 5 UniProtKB/TrEMBL
  TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 6 UniProtKB/TrEMBL
Pfam Ank_2 UniProtKB/TrEMBL
  Ion_trans UniProtKB/TrEMBL
PRINTS ANKYRIN UniProtKB/TrEMBL
  ECACCHANNEL UniProtKB/TrEMBL
  ECACCHANNEL1 UniProtKB/TrEMBL
  ECACCHANNEL2 UniProtKB/TrEMBL
PROSITE ANK_REP_REGION UniProtKB/TrEMBL
  ANK_REPEAT UniProtKB/TrEMBL
SMART ANK UniProtKB/TrEMBL
Superfamily-SCOP SSF48403 UniProtKB/TrEMBL
UniProt A0A286ZUB6_PIG UniProtKB/TrEMBL
  A0A480QGB9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0MU24 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0SWK0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1G440 ENTREZGENE
  F1SRU0_PIG UniProtKB/TrEMBL
UniProt Secondary A0A8D1G440 UniProtKB/TrEMBL
  F1SRU1 UniProtKB/TrEMBL
VGNC ID VGNC:108162 ENTREZGENE