ANG (angiogenin) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: ANG (angiogenin) Sus scrofa
Analyze
Symbol: ANG
Name: angiogenin
RGD ID: 14013658
Description: ENCODES a protein that exhibits protein homodimerization activity (ortholog); INVOLVED IN angiogenesis (ortholog); ASSOCIATED WITH Acute-Phase Reaction (ortholog); Alzheimer's disease (ortholog); amyotrophic lateral sclerosis type 10 (ortholog); FOUND IN growth cone (ortholog); neuronal cell body (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ANG1; Ribonuclease 5; RNase 5
RGD Orthologs
Human
Mouse
Rat
Bonobo
Squirrel
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl778,249,487 - 78,250,138 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1778,249,479 - 78,262,846 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:19247805   PMID:22301074   PMID:30032202   PMID:31549540  


Genomics

Comparative Map Data
ANG
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl778,249,487 - 78,250,138 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1778,249,479 - 78,262,846 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
ANG
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381420,684,177 - 20,694,186 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1420,684,177 - 20,698,971 (+)EnsemblGRCh38hg38GRCh38
GRCh371421,152,336 - 21,162,345 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361420,222,176 - 20,232,185 (+)NCBINCBI36Build 36hg18NCBI36
Build 341420,222,608 - 20,232,183NCBI
Celera141,013,208 - 1,023,217 (+)NCBICelera
Cytogenetic Map14q11.2NCBI
HuRef141,273,259 - 1,283,264 (+)NCBIHuRef
CHM1_11421,154,356 - 21,164,361 (+)NCBICHM1_1
T2T-CHM13v2.01414,881,287 - 14,891,295 (+)NCBIT2T-CHM13v2.0
Ang
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391451,328,607 - 51,339,462 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1451,328,607 - 51,339,466 (+)EnsemblGRCm39 Ensembl
GRCm381451,091,077 - 51,102,009 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1451,091,150 - 51,102,009 (+)EnsemblGRCm38mm10GRCm38
MGSCv371451,710,752 - 51,721,684 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361450,018,364 - 50,023,956 (+)NCBIMGSCv36mm8
Celera1447,385,172 - 47,396,946 (+)NCBICelera
Cytogenetic Map14C1NCBI
cM Map1426.37NCBI
Ang
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81526,786,233 - 26,796,883 (+)NCBIGRCr8
mRatBN7.21524,312,711 - 24,323,361 (+)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_Utx1527,093,931 - 27,094,368 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01528,053,067 - 28,053,504 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01526,302,490 - 26,302,927 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01528,022,926 - 28,028,636 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01531,854,833 - 31,859,801 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41527,083,089 - 27,083,526 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1524,640,646 - 24,641,083 (+)NCBICelera
Cytogenetic Map15p14NCBI
ANG
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21522,184,500 - 22,194,602 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11421,400,986 - 21,410,662 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0141,548,693 - 1,558,528 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11419,605,854 - 19,615,571 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1419,614,950 - 19,615,393 (+)Ensemblpanpan1.1panPan2
Ang
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864032,124,921 - 32,130,709 (+)NCBIHiC_Itri_2
SpeTri2.0NW_00493688039,372 - 40,070 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ANG
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12921,215,985 - 21,226,927 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605925,203,862 - 25,214,926 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in ANG
149 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 6 1 2 3 2
Low 4 3 3 3 2 21 2 1
Below cutoff 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000044088   ⟹   ENSSSCP00000038692
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl778,248,732 - 78,260,147 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000044269   ⟹   ENSSSCP00000068285
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl778,243,691 - 78,244,930 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000065893   ⟹   ENSSSCP00000037223
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl778,249,487 - 78,250,138 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000067644   ⟹   ENSSSCP00000062620
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl778,243,692 - 78,262,830 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000076822   ⟹   ENSSSCP00000068632
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl778,243,714 - 78,244,930 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000078526   ⟹   ENSSSCP00000068520
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl778,243,697 - 78,244,930 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000078860   ⟹   ENSSSCP00000071309
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl778,243,697 - 78,244,930 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000082946   ⟹   ENSSSCP00000074132
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl778,249,487 - 78,262,814 (-)Ensembl
RefSeq Acc Id: NM_001044573   ⟹   NP_001038038
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1778,249,676 - 78,250,140 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021098367   ⟹   XP_020954026
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1778,249,479 - 78,262,846 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020954026   ⟸   XM_021098367
- Peptide Label: isoform X1
- UniProtKB: A0A4X1UVR5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001038038   ⟸   NM_001044573
- Peptide Label: precursor
- UniProtKB: Q1HDU1 (UniProtKB/TrEMBL),   A0A8D0QG20 (UniProtKB/TrEMBL),   A0A287A0F3 (UniProtKB/TrEMBL),   A0A8D0LNL7 (UniProtKB/TrEMBL),   A0A8D1GP79 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000068520   ⟸   ENSSSCT00000078526
RefSeq Acc Id: ENSSSCP00000071309   ⟸   ENSSSCT00000078860
RefSeq Acc Id: ENSSSCP00000038692   ⟸   ENSSSCT00000044088
RefSeq Acc Id: ENSSSCP00000068285   ⟸   ENSSSCT00000044269
RefSeq Acc Id: ENSSSCP00000037223   ⟸   ENSSSCT00000065893
RefSeq Acc Id: ENSSSCP00000068632   ⟸   ENSSSCT00000076822
RefSeq Acc Id: ENSSSCP00000062620   ⟸   ENSSSCT00000067644
RefSeq Acc Id: ENSSSCP00000074132   ⟸   ENSSSCT00000082946
Protein Domains
Ribonuclease A-domain


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000031538 Ensembl, UniProtKB/TrEMBL
  ENSSSCG00000059608 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005022658 UniProtKB/TrEMBL
  ENSSSCG00015081231 UniProtKB/TrEMBL
  ENSSSCG00025004731 UniProtKB/TrEMBL
  ENSSSCG00030041623 UniProtKB/TrEMBL
  ENSSSCG00035000933 UniProtKB/TrEMBL
  ENSSSCG00040017428 UniProtKB/TrEMBL
  ENSSSCG00045004300 UniProtKB/TrEMBL
  ENSSSCG00050003361 UniProtKB/TrEMBL
  ENSSSCG00055015921 UniProtKB/TrEMBL
  ENSSSCG00060027285 UniProtKB/TrEMBL
  ENSSSCG00065059715 UniProtKB/TrEMBL
  ENSSSCG00070019793 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000044269.3 UniProtKB/TrEMBL
  ENSSSCT00000065893 ENTREZGENE
  ENSSSCT00000065893.3 UniProtKB/TrEMBL
  ENSSSCT00000076822.2 UniProtKB/TrEMBL
  ENSSSCT00000078526.2 UniProtKB/TrEMBL
  ENSSSCT00000078860.2 UniProtKB/TrEMBL
  ENSSSCT00005035923.1 UniProtKB/TrEMBL
  ENSSSCT00015110788.1 UniProtKB/TrEMBL
  ENSSSCT00025006406.1 UniProtKB/TrEMBL
  ENSSSCT00030057853.1 UniProtKB/TrEMBL
  ENSSSCT00030057871.1 UniProtKB/TrEMBL
  ENSSSCT00030057924.1 UniProtKB/TrEMBL
  ENSSSCT00035001126.1 UniProtKB/TrEMBL
  ENSSSCT00040023622.1 UniProtKB/TrEMBL
  ENSSSCT00045007166.1 UniProtKB/TrEMBL
  ENSSSCT00045007176.1 UniProtKB/TrEMBL
  ENSSSCT00045007183.1 UniProtKB/TrEMBL
  ENSSSCT00050004466.1 UniProtKB/TrEMBL
  ENSSSCT00050004476.1 UniProtKB/TrEMBL
  ENSSSCT00050004529.1 UniProtKB/TrEMBL
  ENSSSCT00055031473.1 UniProtKB/TrEMBL
  ENSSSCT00060036979.1 UniProtKB/TrEMBL
  ENSSSCT00065081814.1 UniProtKB/TrEMBL
  ENSSSCT00070039201.1 UniProtKB/TrEMBL
  ENSSSCT00070039206.1 UniProtKB/TrEMBL
  ENSSSCT00070039208.1 UniProtKB/TrEMBL
  ENSSSCT00070039214.1 UniProtKB/TrEMBL
Gene3D-CATH 3.10.130.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro RNaseA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RNaseA-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RNaseA_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RNaseA_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report ssc:733639 UniProtKB/TrEMBL
NCBI Gene ANG ENTREZGENE
PANTHER ANGIOGENIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11437 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RIBONUCLEASE 4 UniProtKB/TrEMBL
Pfam RnaseA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS RIBONUCLEASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE RNASE_PANCREATIC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART RNAse_Pc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54076 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A287A0F3 ENTREZGENE
  A0A4X1UVQ0_PIG UniProtKB/TrEMBL
  A0A4X1UVQ4_PIG UniProtKB/TrEMBL
  A0A4X1UVR5 ENTREZGENE, UniProtKB/TrEMBL
  A0A5G2R2I5_PIG UniProtKB/TrEMBL
  A0A5G2R360_PIG UniProtKB/TrEMBL
  A0A8D0LNL7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0QG20 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1GP79 ENTREZGENE, UniProtKB/TrEMBL
  ANGI_PIG UniProtKB/Swiss-Prot, ENTREZGENE
  Q1HDU1 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A287A0F3 UniProtKB/TrEMBL
  A0A5G2QWJ4 UniProtKB/TrEMBL