SLC22A16 (solute carrier family 22 member 16) - Rat Genome Database

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Gene: SLC22A16 (solute carrier family 22 member 16) Sus scrofa
Analyze
Symbol: SLC22A16
Name: solute carrier family 22 member 16
RGD ID: 13960121
Description: ENCODES a protein that exhibits amine transmembrane transporter activity (inferred); carnitine transmembrane transporter activity (inferred); organic cation transmembrane transporter activity (inferred); INVOLVED IN carnitine transport (ortholog); organic cation transport (ortholog); PARTICIPATES IN doxorubicin pharmacokinetics pathway; ASSOCIATED WITH COVID-19 (ortholog); juvenile rheumatoid arthritis (ortholog); FOUND IN cytosol (inferred); membrane (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: solute carrier family 22 (organic cation/carnitine transporter), member 16
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl176,423,355 - 76,467,575 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1176,423,386 - 76,468,267 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2186,021,436 - 86,064,197 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IEA)
membrane  (IEA)
plasma membrane  (IEA)

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SLC22A16
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl176,423,355 - 76,467,575 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1176,423,386 - 76,468,267 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2186,021,436 - 86,064,197 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLC22A16
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386110,424,687 - 110,476,613 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6110,424,687 - 110,476,641 (-)EnsemblGRCh38hg38GRCh38
GRCh376110,745,890 - 110,797,816 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366110,852,599 - 110,904,537 (-)NCBINCBI36Build 36hg18NCBI36
Build 346110,852,602 - 110,904,537NCBI
Celera6111,492,526 - 111,544,454 (-)NCBICelera
Cytogenetic Map6q21NCBI
HuRef6108,312,812 - 108,364,722 (-)NCBIHuRef
CHM1_16111,009,079 - 111,061,055 (-)NCBICHM1_1
T2T-CHM13v2.06111,603,183 - 111,655,121 (-)NCBIT2T-CHM13v2.0
Slc22a16
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391040,446,317 - 40,480,128 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1040,446,332 - 40,480,128 (+)EnsemblGRCm39 Ensembl
GRCm381040,570,321 - 40,604,132 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1040,570,336 - 40,604,132 (+)EnsemblGRCm38mm10GRCm38
MGSCv371040,290,168 - 40,323,938 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361040,259,752 - 40,293,557 (+)NCBIMGSCv36mm8
Celera1041,459,880 - 41,493,899 (+)NCBICelera
Cytogenetic Map10B1NCBI
cM Map1021.99NCBI
Slc22a16
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82045,527,275 - 45,647,675 (+)NCBIGRCr8
mRatBN7.22043,972,808 - 44,068,447 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2043,972,836 - 44,065,019 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.02045,658,398 - 45,669,192 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02047,377,218 - 47,389,105 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera2044,675,285 - 44,692,225 (+)NCBICelera
Cytogenetic Map20q12NCBI
SLC22A16
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25130,438,134 - 130,490,825 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16128,324,168 - 128,376,849 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06108,232,950 - 108,332,469 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16112,302,079 - 112,354,629 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6112,302,265 - 112,354,829 (-)Ensemblpanpan1.1panPan2
SLC22A16
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11267,110,606 - 67,167,812 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1267,110,606 - 67,149,880 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1266,930,237 - 66,986,909 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01267,995,002 - 68,050,363 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1267,995,015 - 68,037,024 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11267,346,263 - 67,401,153 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01267,192,304 - 67,247,319 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01267,464,534 - 67,521,660 (-)NCBIUU_Cfam_GSD_1.0
Slc22a16
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946102,036,912 - 102,078,052 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365646,311,934 - 6,352,759 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC22A16
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11363,422,540 - 63,474,920 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1363,442,867 - 63,474,874 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604035,665,444 - 35,767,647 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in SLC22A16
1484 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system musculoskeletal system nervous system renal system reproductive system
High
Medium 1 1
Low 2 1 5 2
Below cutoff 1 8

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000004862   ⟹   ENSSSCP00000004747
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl176,423,355 - 76,467,575 (-)Ensembl
RefSeq Acc Id: XM_003121349   ⟹   XP_003121397
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1176,423,386 - 76,467,782 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021091125   ⟹   XP_020946784
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1176,423,386 - 76,468,267 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020946784   ⟸   XM_021091125
- Peptide Label: isoform X2
- UniProtKB: A0A8D0LUT5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003121397   ⟸   XM_003121349
- Peptide Label: isoform X1
- UniProtKB: F1RT02 (UniProtKB/TrEMBL),   A0A8D1RPU4 (UniProtKB/TrEMBL),   A0A8D0LUT5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000004747   ⟸   ENSSSCT00000004862
Protein Domains
Major facilitator superfamily (MFS) profile


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000004399 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005037595 UniProtKB/TrEMBL
  ENSSSCG00015027042 UniProtKB/TrEMBL
  ENSSSCG00025048566 UniProtKB/TrEMBL
  ENSSSCG00030000102 UniProtKB/TrEMBL
  ENSSSCG00035019725 UniProtKB/TrEMBL
  ENSSSCG00040070810 UniProtKB/TrEMBL
  ENSSSCG00050049840 UniProtKB/TrEMBL
  ENSSSCG00055023717 UniProtKB/TrEMBL
  ENSSSCG00060034578 UniProtKB/TrEMBL
  ENSSSCG00065034221 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000004862 ENTREZGENE
  ENSSSCT00000004862.5 UniProtKB/TrEMBL
  ENSSSCT00005060049.1 UniProtKB/TrEMBL
  ENSSSCT00015035877.1 UniProtKB/TrEMBL
  ENSSSCT00025066087.1 UniProtKB/TrEMBL
  ENSSSCT00030000197.1 UniProtKB/TrEMBL
  ENSSSCT00035025568.1 UniProtKB/TrEMBL
  ENSSSCT00040097239.1 UniProtKB/TrEMBL
  ENSSSCT00050067799.1 UniProtKB/TrEMBL
  ENSSSCT00055046639.1 UniProtKB/TrEMBL
  ENSSSCT00060046863.1 UniProtKB/TrEMBL
  ENSSSCT00065046556.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1250.20 UniProtKB/TrEMBL
InterPro MFS_dom UniProtKB/TrEMBL
  MFS_sugar_transport-like UniProtKB/TrEMBL
  MFS_trans_sf UniProtKB/TrEMBL
KEGG Report ssc:100525793 UniProtKB/TrEMBL
NCBI Gene SLC22A16 ENTREZGENE
PANTHER SOLUTE CARRIER FAMILY 22 MEMBER UniProtKB/TrEMBL
  SOLUTE CARRIER FAMILY 22 MEMBER 16 UniProtKB/TrEMBL
Pfam Sugar_tr UniProtKB/TrEMBL
PROSITE MFS UniProtKB/TrEMBL
Superfamily-SCOP SSF103473 UniProtKB/TrEMBL
UniProt A0A8D0LUT5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1RPU4 ENTREZGENE, UniProtKB/TrEMBL
  F1RT02 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:92976 ENTREZGENE