ZW10 (zw10 kinetochore protein) - Rat Genome Database

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Gene: ZW10 (zw10 kinetochore protein) Sus scrofa
Analyze
Symbol: ZW10
Name: zw10 kinetochore protein
RGD ID: 13911179
Description: INVOLVED IN cell division (inferred); endoplasmic reticulum to Golgi vesicle-mediated transport (inferred); establishment of mitotic spindle orientation (inferred); ASSOCIATED WITH Chromosome 11, Partial Trisomy 11q (ortholog); intellectual disability (ortholog); osteosarcoma (ortholog); FOUND IN Dsl1/NZR complex (ortholog); RZZ complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: centromere/kinetochore protein zw10 homolog
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl941,348,896 - 41,400,208 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1941,358,801 - 41,400,254 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ZW10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl941,348,896 - 41,400,208 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1941,358,801 - 41,400,254 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
ZW10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811113,733,187 - 113,773,692 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11113,733,187 - 113,773,735 (-)EnsemblGRCh38hg38GRCh38
GRCh3711113,603,909 - 113,644,414 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611113,109,119 - 113,149,635 (-)NCBINCBI36Build 36hg18NCBI36
Build 3411113,109,119 - 113,149,635NCBI
Celera11110,756,828 - 110,797,319 (-)NCBICelera
Cytogenetic Map11q23.2NCBI
HuRef11109,532,443 - 109,573,027 (-)NCBIHuRef
CHM1_111113,487,178 - 113,527,780 (-)NCBICHM1_1
T2T-CHM13v2.011113,743,514 - 113,784,012 (-)NCBIT2T-CHM13v2.0
Zw10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39948,966,880 - 48,990,075 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl948,966,913 - 48,990,075 (+)EnsemblGRCm39 Ensembl
GRCm38949,055,576 - 49,078,775 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl949,055,613 - 49,078,775 (+)EnsemblGRCm38mm10GRCm38
MGSCv37948,863,737 - 48,886,878 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36948,807,564 - 48,830,705 (+)NCBIMGSCv36mm8
Celera946,352,736 - 46,375,856 (+)NCBICelera
Cytogenetic Map9A5.3NCBI
cM Map926.58NCBI
Zw10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8858,292,959 - 58,317,881 (+)NCBIGRCr8
mRatBN7.2849,396,541 - 49,424,743 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl849,396,545 - 49,421,805 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx854,902,405 - 54,927,272 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0853,181,278 - 53,206,138 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0851,045,529 - 51,070,395 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0853,365,881 - 53,390,742 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl853,365,857 - 53,390,930 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0851,980,064 - 52,005,883 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4852,316,233 - 52,341,095 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1852,335,286 - 52,360,149 (+)NCBI
Celera848,953,761 - 48,978,510 (+)NCBICelera
Cytogenetic Map8q23NCBI
Zw10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541215,350,285 - 15,391,996 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541215,354,918 - 15,391,233 (-)NCBIChiLan1.0ChiLan1.0
ZW10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29114,476,266 - 114,517,225 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111115,570,599 - 115,611,545 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011108,611,818 - 108,652,444 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111112,454,637 - 112,494,959 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11112,454,637 - 112,495,316 (-)Ensemblpanpan1.1panPan2
ZW10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1519,496,531 - 19,527,205 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl519,496,611 - 19,527,200 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha519,419,964 - 19,450,401 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0519,517,162 - 19,548,136 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl519,517,176 - 19,573,826 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1519,581,032 - 19,611,948 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0519,481,791 - 19,512,726 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0519,529,918 - 19,560,842 (+)NCBIUU_Cfam_GSD_1.0
Zw10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494795,842,340 - 95,880,186 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936612825,419 - 860,971 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936612825,419 - 860,971 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZW10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11105,108,531 - 105,152,921 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1105,109,040 - 105,152,862 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604320,866,303 - 20,906,831 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Zw10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247849,221,128 - 9,255,284 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247849,221,123 - 9,255,294 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ZW10
1058 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 9 2 3 5 9 2 3
Low 1 2 2 14 2 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000016416   ⟹   ENSSSCP00000015975
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl941,356,010 - 41,400,208 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000044232   ⟹   ENSSSCP00000038430
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl941,356,001 - 41,400,304 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000045559   ⟹   ENSSSCP00000046544
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl941,358,808 - 41,400,201 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000056103   ⟹   ENSSSCP00000057626
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl941,358,801 - 41,400,207 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000065080   ⟹   ENSSSCP00000048309
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl941,364,759 - 41,400,208 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000077367   ⟹   ENSSSCP00000063846
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl941,348,896 - 41,390,801 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000078349   ⟹   ENSSSCP00000064743
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl941,356,010 - 41,400,208 (-)Ensembl
RefSeq Acc Id: XM_021062840   ⟹   XP_020918499
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1941,358,801 - 41,400,254 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020918499   ⟸   XM_021062840
- UniProtKB: A0A4X1T8H9 (UniProtKB/TrEMBL),   F1SM67 (UniProtKB/TrEMBL),   A0A8D1JMR7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000064743   ⟸   ENSSSCT00000078349
RefSeq Acc Id: ENSSSCP00000038430   ⟸   ENSSSCT00000044232
RefSeq Acc Id: ENSSSCP00000048309   ⟸   ENSSSCT00000065080
RefSeq Acc Id: ENSSSCP00000015975   ⟸   ENSSSCT00000016416
RefSeq Acc Id: ENSSSCP00000046544   ⟸   ENSSSCT00000045559
RefSeq Acc Id: ENSSSCP00000057626   ⟸   ENSSSCT00000056103
RefSeq Acc Id: ENSSSCP00000063846   ⟸   ENSSSCT00000077367
Protein Domains
Centromere/kinetochore protein zw10 C-terminal   Centromere/kinetochore protein zw10 middle   Centromere/kinetochore protein zw10 N-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000015050 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005017645 UniProtKB/TrEMBL
  ENSSSCG00015006902 UniProtKB/TrEMBL
  ENSSSCG00025028575 UniProtKB/TrEMBL
  ENSSSCG00030066499 UniProtKB/TrEMBL
  ENSSSCG00045007412 UniProtKB/TrEMBL
  ENSSSCG00050006053 UniProtKB/TrEMBL
  ENSSSCG00055011245 UniProtKB/TrEMBL
  ENSSSCG00060003155 UniProtKB/TrEMBL
  ENSSSCG00065009833 UniProtKB/TrEMBL
  ENSSSCG00070007231 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000016416 ENTREZGENE
  ENSSSCT00000016416.5 UniProtKB/TrEMBL
  ENSSSCT00000045559.1 UniProtKB/TrEMBL
  ENSSSCT00000056103.3 UniProtKB/TrEMBL
  ENSSSCT00000065080.2 UniProtKB/TrEMBL
  ENSSSCT00000077367.2 UniProtKB/TrEMBL
  ENSSSCT00000078349.2 UniProtKB/TrEMBL
  ENSSSCT00005029456.1 UniProtKB/TrEMBL
  ENSSSCT00015009381.1 UniProtKB/TrEMBL
  ENSSSCT00015009520.1 UniProtKB/TrEMBL
  ENSSSCT00025038847.1 UniProtKB/TrEMBL
  ENSSSCT00025039014.1 UniProtKB/TrEMBL
  ENSSSCT00025039160.1 UniProtKB/TrEMBL
  ENSSSCT00025039315.1 UniProtKB/TrEMBL
  ENSSSCT00030093027.1 UniProtKB/TrEMBL
  ENSSSCT00030093124.1 UniProtKB/TrEMBL
  ENSSSCT00030093165.1 UniProtKB/TrEMBL
  ENSSSCT00045012347.1 UniProtKB/TrEMBL
  ENSSSCT00045012442.1 UniProtKB/TrEMBL
  ENSSSCT00050008241.1 UniProtKB/TrEMBL
  ENSSSCT00050008259.1 UniProtKB/TrEMBL
  ENSSSCT00055022187.1 UniProtKB/TrEMBL
  ENSSSCT00055022230.1 UniProtKB/TrEMBL
  ENSSSCT00055022260.1 UniProtKB/TrEMBL
  ENSSSCT00060003918.1 UniProtKB/TrEMBL
  ENSSSCT00060003925.1 UniProtKB/TrEMBL
  ENSSSCT00060003937.1 UniProtKB/TrEMBL
  ENSSSCT00060003939.1 UniProtKB/TrEMBL
  ENSSSCT00060003943.1 UniProtKB/TrEMBL
  ENSSSCT00065013180.1 UniProtKB/TrEMBL
  ENSSSCT00065013190.1 UniProtKB/TrEMBL
  ENSSSCT00065013193.1 UniProtKB/TrEMBL
  ENSSSCT00070013984.1 UniProtKB/TrEMBL
  ENSSSCT00070013989.1 UniProtKB/TrEMBL
  ENSSSCT00070014007.1 UniProtKB/TrEMBL
  ENSSSCT00070014009.1 UniProtKB/TrEMBL
  ENSSSCT00070014018.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.357.150 UniProtKB/TrEMBL
InterPro RZZ-complex_Zw10 UniProtKB/TrEMBL
  Zw10/DSL1_C_sf UniProtKB/TrEMBL
  ZW10_C UniProtKB/TrEMBL
  Zw10_middle UniProtKB/TrEMBL
NCBI Gene ZW10 ENTREZGENE
PANTHER CENTROMERE/KINETOCHORE PROTEIN ZW10 UniProtKB/TrEMBL
  CENTROMERE/KINETOCHORE PROTEIN ZW10 HOMOLOG UniProtKB/TrEMBL
Pfam Zw10 UniProtKB/TrEMBL
  ZW10_C UniProtKB/TrEMBL
  Zw10_middle UniProtKB/TrEMBL
UniProt A0A287AWJ4_PIG UniProtKB/TrEMBL
  A0A287BNH2_PIG UniProtKB/TrEMBL
  A0A4X1T8F7_PIG UniProtKB/TrEMBL
  A0A4X1T8H9 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1T8J0_PIG UniProtKB/TrEMBL
  A0A4X1T911_PIG UniProtKB/TrEMBL
  A0A4X1T9Q7_PIG UniProtKB/TrEMBL
  A0A5G2QIV5_PIG UniProtKB/TrEMBL
  A0A5G2QJS6_PIG UniProtKB/TrEMBL
  A0A8D0RGI5_PIG UniProtKB/TrEMBL
  A0A8D1JMR7 ENTREZGENE, UniProtKB/TrEMBL
  F1SM67 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A287ARQ7 UniProtKB/TrEMBL
VGNC ID VGNC:95340 ENTREZGENE