Zw10 (zw10 kinetochore protein) - Rat Genome Database

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Gene: Zw10 (zw10 kinetochore protein) Ictidomys tridecemlineatus
Analyze
Symbol: Zw10
Name: zw10 kinetochore protein
RGD ID: 12644761
Description: INVOLVED IN cell division (inferred); endoplasmic reticulum to Golgi vesicle-mediated transport (inferred); establishment of mitotic spindle orientation (inferred); ASSOCIATED WITH Chromosome 11, Partial Trisomy 11q (ortholog); intellectual disability (ortholog); osteosarcoma (ortholog); FOUND IN Dsl1/NZR complex (ortholog); RZZ complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: centromere/kinetochore protein zw10 homolog
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494795,842,340 - 95,880,186 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936612825,419 - 860,971 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936612825,419 - 860,971 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Zw10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494795,842,340 - 95,880,186 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936612825,419 - 860,971 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936612825,419 - 860,971 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZW10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811113,733,187 - 113,773,692 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11113,733,187 - 113,773,735 (-)EnsemblGRCh38hg38GRCh38
GRCh3711113,603,909 - 113,644,414 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611113,109,119 - 113,149,635 (-)NCBINCBI36Build 36hg18NCBI36
Build 3411113,109,119 - 113,149,635NCBI
Celera11110,756,828 - 110,797,319 (-)NCBICelera
Cytogenetic Map11q23.2NCBI
HuRef11109,532,443 - 109,573,027 (-)NCBIHuRef
CHM1_111113,487,178 - 113,527,780 (-)NCBICHM1_1
T2T-CHM13v2.011113,743,514 - 113,784,012 (-)NCBIT2T-CHM13v2.0
Zw10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39948,966,880 - 48,990,075 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl948,966,913 - 48,990,075 (+)EnsemblGRCm39 Ensembl
GRCm38949,055,576 - 49,078,775 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl949,055,613 - 49,078,775 (+)EnsemblGRCm38mm10GRCm38
MGSCv37948,863,737 - 48,886,878 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36948,807,564 - 48,830,705 (+)NCBIMGSCv36mm8
Celera946,352,736 - 46,375,856 (+)NCBICelera
Cytogenetic Map9A5.3NCBI
cM Map926.58NCBI
Zw10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8858,292,959 - 58,317,881 (+)NCBIGRCr8
mRatBN7.2849,396,541 - 49,424,743 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl849,396,545 - 49,421,805 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx854,902,405 - 54,927,272 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0853,181,278 - 53,206,138 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0851,045,529 - 51,070,395 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0853,365,881 - 53,390,742 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl853,365,857 - 53,390,930 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0851,980,064 - 52,005,883 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4852,316,233 - 52,341,095 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1852,335,286 - 52,360,149 (+)NCBI
Celera848,953,761 - 48,978,510 (+)NCBICelera
Cytogenetic Map8q23NCBI
Zw10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541215,350,285 - 15,391,996 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541215,354,918 - 15,391,233 (-)NCBIChiLan1.0ChiLan1.0
ZW10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29114,476,266 - 114,517,225 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111115,570,599 - 115,611,545 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011108,611,818 - 108,652,444 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111112,454,637 - 112,494,959 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11112,454,637 - 112,495,316 (-)Ensemblpanpan1.1panPan2
ZW10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1519,496,531 - 19,527,205 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl519,496,611 - 19,527,200 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha519,419,964 - 19,450,401 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0519,517,162 - 19,548,136 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl519,517,176 - 19,573,826 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1519,581,032 - 19,611,948 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0519,481,791 - 19,512,726 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0519,529,918 - 19,560,842 (+)NCBIUU_Cfam_GSD_1.0
ZW10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl941,348,896 - 41,400,208 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1941,358,801 - 41,400,254 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
ZW10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11105,108,531 - 105,152,921 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1105,109,040 - 105,152,862 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604320,866,303 - 20,906,831 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Zw10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247849,221,128 - 9,255,284 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247849,221,123 - 9,255,294 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005334207 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSTOT00000008806   ⟹   ENSSTOP00000007894
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936612825,419 - 860,971 (+)Ensembl
RefSeq Acc Id: XM_005334207   ⟹   XP_005334264
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494795,842,340 - 95,880,186 (-)NCBI
SpeTri2.0NW_004936612825,419 - 860,971 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005334264 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000007894.3
GenBank Protein KAG3286572 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005334264   ⟸   XM_005334207
- UniProtKB: I3MCB8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSTOP00000007894   ⟸   ENSSTOT00000008806
Protein Domains
Centromere/kinetochore protein zw10 C-terminal   Centromere/kinetochore protein zw10 middle   Centromere/kinetochore protein zw10 N-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000008796 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000008806.3 UniProtKB/TrEMBL
Gene3D-CATH 1.10.357.150 UniProtKB/TrEMBL
InterPro RZZ-complex_Zw10 UniProtKB/TrEMBL
  Zw10/DSL1_C_sf UniProtKB/TrEMBL
  ZW10_C UniProtKB/TrEMBL
  Zw10_middle UniProtKB/TrEMBL
NCBI Gene Zw10 ENTREZGENE
PANTHER CENTROMERE/KINETOCHORE PROTEIN ZW10 UniProtKB/TrEMBL
  CENTROMERE/KINETOCHORE PROTEIN ZW10 HOMOLOG UniProtKB/TrEMBL
Pfam Zw10 UniProtKB/TrEMBL
  ZW10_C UniProtKB/TrEMBL
  Zw10_middle UniProtKB/TrEMBL
UniProt I3MCB8 ENTREZGENE, UniProtKB/TrEMBL