SIRT5 (sirtuin 5) - Rat Genome Database

Name: SIRT5
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: SIRT5 (sirtuin 5) Sus scrofa

Analyze

Symbol:

SIRT5

Name:

sirtuin 5

RGD ID:

13892792

Description:

ENCODES a protein that exhibits metal ion binding (inferred); NAD+ binding (inferred); NAD-dependent histone deacetylase activity (inferred); INVOLVED IN negative regulation of cardiac muscle cell apoptotic process (ortholog); regulation of ketone biosynthetic process (ortholog); response to ischemia (ortholog); PARTICIPATES IN histone modification pathway; Sirtuin mediated pathway; FOUND IN mitochondrial inner membrane (ortholog); mitochondrion (ortholog)

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

NAD-dependent protein deacylase sirtuin-5, mitochondrial

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SIRT5 (sirtuin 5)	HGNC	Ensembl, NCBI, OrthoDB
Mus musculus (house mouse):	Sirt5 (sirtuin 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Sirt5 (sirtuin 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Sirt5 (sirtuin 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SIRT5 (sirtuin 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SIRT5 (sirtuin 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Sirt5 (sirtuin 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SIRT5 (sirtuin 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Sirt5 (sirtuin 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	9,951,030 - 9,968,448 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	9,951,024 - 9,968,004 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	10,327,724 - 10,330,511 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

chromatin remodeling (IEA)

epigenetic regulation of gene expression (IBA)

negative regulation of cardiac muscle cell apoptotic process (ISO)

negative regulation of reactive oxygen species metabolic process (IEA)

regulation of ketone biosynthetic process (ISO)

response to ischemia (ISO)

response to nutrient levels (ISO)

Cellular Component

cytoplasm (IEA)

cytosol (IEA)

mitochondrial inner membrane (ISO)

mitochondrial intermembrane space (IEA)

mitochondrial matrix (IBA,IEA)

mitochondrion (IEA,ISO)

nucleus (IEA)

Molecular Function

metal ion binding (IEA)

NAD+ binding (IEA)

NAD-dependent histone deacetylase activity (IEA)

NAD-dependent protein lysine deacetylase activity (IEA)

protein binding (ISO)

protein-glutaryllysine deglutarylase activity (IBA,IEA)

protein-malonyllysine demalonylase activity (IBA,IEA)

protein-succinyllysine desuccinylase activity (IBA,IEA)

transferase activity (IEA)

zinc ion binding (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

histone modification pathway (ISO)

Sirtuin mediated pathway (ISO)

References

Additional References at PubMed

PMID:14681463	PMID:17145712	PMID:19389481	PMID:22301074

Genomics

Comparative Map Data

SIRT5
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	9,951,030 - 9,968,448 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	9,951,024 - 9,968,004 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	10,327,724 - 10,330,511 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SIRT5
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	13,574,274 - 13,615,158 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	13,574,227 - 13,615,158 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	13,574,506 - 13,615,390 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	13,682,812 - 13,720,500 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	13,682,811 - 13,713,947	NCBI
Celera	6	14,814,287 - 14,854,285 (+)	NCBI		Celera
Cytogenetic Map	6	p23	NCBI
HuRef	6	13,519,134 - 13,559,766 (+)	NCBI		HuRef
CHM1_1	6	13,577,139 - 13,617,757 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	6	13,447,831 - 13,488,715 (+)	NCBI		T2T-CHM13v2.0

Sirt5
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	13	43,518,849 - 43,549,073 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	13	43,518,972 - 43,548,679 (+)	Ensembl		GRCm39 Ensembl
GRCm38	13	43,365,389 - 43,395,203 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	13	43,365,496 - 43,395,203 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	13	43,460,904 - 43,490,572 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	13	43,376,507 - 43,406,175 (+)	NCBI		MGSCv36	mm8
Celera	13	44,444,248 - 44,473,768 (+)	NCBI		Celera
Cytogenetic Map	13	A4	NCBI
cM Map	13	21.6	NCBI

Sirt5
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	17	21,515,982 - 21,543,529 (-)	NCBI		GRCr8
mRatBN7.2	17	21,310,028 - 21,337,137 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	17	21,310,028 - 21,337,101 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	17	21,198,845 - 21,226,111 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	17	22,802,514 - 22,829,782 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	17	21,125,948 - 21,153,215 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	17	23,986,710 - 24,013,854 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	17	23,986,758 - 24,013,881 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	17	25,936,391 - 25,963,434 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	17	27,135,610 - 27,162,715 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	17	27,138,453 - 27,165,556 (-)	NCBI
Celera	17	21,007,452 - 21,034,513 (-)	NCBI		Celera
Cytogenetic Map	17	p14	NCBI

Sirt5
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955465	1,129,217 - 1,167,604 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955465	1,129,217 - 1,167,604 (-)	NCBI	ChiLan1.0	ChiLan1.0

SIRT5
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	28,228,262 - 28,266,098 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	24,218,286 - 24,256,255 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	13,419,242 - 13,457,200 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	13,790,576 - 13,828,464 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	13,791,112 - 13,828,464 (+)	Ensembl	panpan1.1		panPan2

SIRT5
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	35	13,017,397 - 13,055,655 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	35	13,017,397 - 13,063,022 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	35	12,966,806 - 13,004,993 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	35	13,115,780 - 13,154,165 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	35	13,115,780 - 13,179,805 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	35	12,941,308 - 12,979,591 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	35	12,994,546 - 13,031,107 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	35	14,317,852 - 14,356,107 (+)	NCBI		UU_Cfam_GSD_1.0

Sirt5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	11,516,904 - 11,539,107 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936552	192,226 - 214,030 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936552	192,182 - 214,037 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SIRT5
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	17	58,535,645 - 58,573,769 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	17	58,532,650 - 58,563,818 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666044	13,624,450 - 13,664,862 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Sirt5
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624756	12,678,877 - 12,706,604 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624756	12,678,866 - 12,705,862 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in SIRT5
789 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	hemolymphoid system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system
High
Medium	2	2	2	1	2	13	2
Low	8	2	1	4		10		3	3
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001105308	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000051	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK350144	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK398688	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK400225	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU457756	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	EU100953	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	EU357901	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GFLN01100125	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSSCT00000039420 ⟹ ENSSSCP00000042575

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	7	9,951,030 - 9,968,448 (+)	Ensembl

RefSeq Acc Id:

ENSSSCT00000070505 ⟹ ENSSSCP00000073575

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	7	9,951,030 - 9,968,448 (+)	Ensembl

RefSeq Acc Id:

ENSSSCT00000104892 ⟹ ENSSSCP00000075685

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	7	9,951,030 - 9,968,446 (+)	Ensembl

RefSeq Acc Id:

NM_001105308 ⟹ NP_001098778

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	7	9,951,024 - 9,968,004 (+)	NCBI

Sequence:

show sequence

AACCTGATGCCACCTCTCTGGGGCGTCCCGGGCCGATTACTTTCCCAGCTGCGTTGTGGGTTGA
CGTCTCCAGCCTCCGCACCAACCAGGATTTGCCCAACAATGGCTCGTCCAAGTTCAAGTATGGC
CGACTTTCGGAAGCATTTTGCAAAAGCCAAGCACATAGTTGTCATTTCGGGGGCTGGTGTTAGT
GCCGAGAGTGGGATTCCGACCTTCAGAGGAGCAGGAGGTTATTGGAGAAAATGGCAAGCTCAGG
ACCTGGCCACCCCTCAGGCCTTTGCCCGAAACCCGTCCCGGGTGTGGGAGTTCTACCACCACCG
GCGGGAGGTGGTGCAGGGCAGGGCGCCCAACGCCGGGCACCTGGCCATCGCCCAGTGTGAGGCC
CGGCTGCACGGGCAGGGCCGCCGGCTCGTGGTCATCACCCAGAACATCGACGAGCTGCACCGCA
AGGCTGGCACCAGGAACCTTCTGGAAATCCATGGTAGTTTGTTTAAAACCCGGTGTACCTCTTG
TGGAGCTGTAGCTGAGAATTACAAGAGTCCAATTTGTCCAGCTTTATCAGGAAAAGGTGCTCCA
GAACCTGAGACTCAAGATGCCAGAATCCCAGTTGAGAAACTCCCTCGGTGTGAAGAGGCGGGAT
GCGGGGGCCTGCTGCGACCTCACGTCGTGTGGTTTGGAGAGAACCTGGACCCTGCCATCCTGGA
GGAGGTTGACAGAGAGCTGGCCCTCTGTGACTTGTGTCTAGTGGTGGGAACGTCCTCGGTGGTC
TACCCCGCGGCCCTCTTCGCCCCACAGGTGTCCGCCCGGGGAGTGCCGGTGGCCGAATTTAATG
TGGAAGCGACCCCCGCCACCAACAGATTCAGGTTTCACTTCCAGGGGCCGTGTGGGACGACTCT
TCCTGAAGCCCTAGCTCCTCATGAAACTGAACCTGTCTCTTAGTCGTCCCG

hide sequence

Protein Sequences


Protein RefSeqs	NP_001098778	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	ABU89799	(Get FASTA)	NCBI Sequence Viewer
	ABY65335	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000042575
	ENSSSCP00000042575.1
	ENSSSCP00000073575.1
	ENSSSCP00000075685.1
	ENSSSCP00005002917.1
	ENSSSCP00005030719.1
	ENSSSCP00005030735.1
	ENSSSCP00005030739.1
	ENSSSCP00005030742.1
	ENSSSCP00005030804.1
	ENSSSCP00015022630.1
	ENSSSCP00015022729.1
	ENSSSCP00015022838.1
	ENSSSCP00025030123.1
	ENSSSCP00025030193.1
	ENSSSCP00030010022.1
	ENSSSCP00030010027.1
	ENSSSCP00035026254.1
	ENSSSCP00035026259.1
	ENSSSCP00040009791.1
	ENSSSCP00040009806.1
	ENSSSCP00045029743.1
	ENSSSCP00045029832.1
	ENSSSCP00050007180.1
	ENSSSCP00050007182.1
	ENSSSCP00050007186.1
	ENSSSCP00050007188.1
	ENSSSCP00050007192.1
	ENSSSCP00055025609.1
	ENSSSCP00055025693.1
	ENSSSCP00060002443.1
	ENSSSCP00060002445.1
	ENSSSCP00065017262.1
	ENSSSCP00065017268.1
	ENSSSCP00070043639.1
	ENSSSCP00070043646.1
	ENSSSCP00070043661.1
	ENSSSCP00070043666.1

RefSeq Acc Id:

NP_001098778 ⟸ NM_001105308

- UniProtKB:

A7XXV9 (UniProtKB/TrEMBL), A0A4X1VJI2 (UniProtKB/TrEMBL), B0FWP7 (UniProtKB/TrEMBL), A0A8D1I6P1 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MPPLWGVPGRLLSQLRCGLTSPASAPTRICPTMARPSSSMADFRKHFAKAKHIVVISGAGVSAE
SGIPTFRGAGGYWRKWQAQDLATPQAFARNPSRVWEFYHHRREVVQGRAPNAGHLAIAQCEARL
HGQGRRLVVITQNIDELHRKAGTRNLLEIHGSLFKTRCTSCGAVAENYKSPICPALSGKGAPEP
ETQDARIPVEKLPRCEEAGCGGLLRPHVVWFGENLDPAILEEVDRELALCDLCLVVGTSSVVYP
AALFAPQVSARGVPVAEFNVEATPATNRFRFHFQGPCGTTLPEALAPHETEPVS

hide sequence

RefSeq Acc Id:

ENSSSCP00000042575 ⟸ ENSSSCT00000039420

RefSeq Acc Id:

ENSSSCP00000073575 ⟸ ENSSSCT00000070505

RefSeq Acc Id:

ENSSSCP00000075685 ⟸ ENSSSCT00000104892

Protein Domains

Deacetylase sirtuin-type

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000031129	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCG00005003449	UniProtKB/TrEMBL
	ENSSSCG00005031195	UniProtKB/TrEMBL
	ENSSSCG00015042376	UniProtKB/TrEMBL
	ENSSSCG00025051121	UniProtKB/TrEMBL
	ENSSSCG00030016010	UniProtKB/TrEMBL
	ENSSSCG00035048674	UniProtKB/TrEMBL
	ENSSSCG00040017259	UniProtKB/TrEMBL
	ENSSSCG00045025131	UniProtKB/TrEMBL
	ENSSSCG00050012911	UniProtKB/TrEMBL
	ENSSSCG00055016307	UniProtKB/TrEMBL
	ENSSSCG00060005508	UniProtKB/TrEMBL
	ENSSSCG00065030217	UniProtKB/TrEMBL
	ENSSSCG00070025817	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000039420	ENTREZGENE
	ENSSSCT00000039420.2	UniProtKB/TrEMBL
	ENSSSCT00000070505.1	UniProtKB/TrEMBL
	ENSSSCT00000104892.1	UniProtKB/TrEMBL
	ENSSSCT00005005086.1	UniProtKB/TrEMBL
	ENSSSCT00005049750.1	UniProtKB/TrEMBL
	ENSSSCT00005049778.1	UniProtKB/TrEMBL
	ENSSSCT00005049788.1	UniProtKB/TrEMBL
	ENSSSCT00005049796.1	UniProtKB/TrEMBL
	ENSSSCT00005049897.1	UniProtKB/TrEMBL
	ENSSSCT00015056466.1	UniProtKB/TrEMBL
	ENSSSCT00015056728.1	UniProtKB/TrEMBL
	ENSSSCT00015057004.1	UniProtKB/TrEMBL
	ENSSSCT00025069861.1	UniProtKB/TrEMBL
	ENSSSCT00025070004.1	UniProtKB/TrEMBL
	ENSSSCT00030022196.1	UniProtKB/TrEMBL
	ENSSSCT00030022210.1	UniProtKB/TrEMBL
	ENSSSCT00035064848.1	UniProtKB/TrEMBL
	ENSSSCT00035064857.1	UniProtKB/TrEMBL
	ENSSSCT00040023253.1	UniProtKB/TrEMBL
	ENSSSCT00040023272.1	UniProtKB/TrEMBL
	ENSSSCT00045042829.1	UniProtKB/TrEMBL
	ENSSSCT00045042946.1	UniProtKB/TrEMBL
	ENSSSCT00050017420.1	UniProtKB/TrEMBL
	ENSSSCT00050017426.1	UniProtKB/TrEMBL
	ENSSSCT00050017434.1	UniProtKB/TrEMBL
	ENSSSCT00050017437.1	UniProtKB/TrEMBL
	ENSSSCT00050017446.1	UniProtKB/TrEMBL
	ENSSSCT00055032161.1	UniProtKB/TrEMBL
	ENSSSCT00055032264.1	UniProtKB/TrEMBL
	ENSSSCT00060006945.1	UniProtKB/TrEMBL
	ENSSSCT00060006947.1	UniProtKB/TrEMBL
	ENSSSCT00065040782.1	UniProtKB/TrEMBL
	ENSSSCT00065040794.1	UniProtKB/TrEMBL
	ENSSSCT00070051601.1	UniProtKB/TrEMBL
	ENSSSCT00070051608.1	UniProtKB/TrEMBL
	ENSSSCT00070051624.1	UniProtKB/TrEMBL
	ENSSSCT00070051629.1	UniProtKB/TrEMBL
Gene3D-CATH	3.30.1600.10	UniProtKB/TrEMBL
	TPP-binding domain	UniProtKB/TrEMBL
InterPro	DHS-like_NAD/FAD-binding_dom	UniProtKB/TrEMBL
	Sirtuin	UniProtKB/TrEMBL
	Sirtuin_cat_small_dom_sf	UniProtKB/TrEMBL
	Sirtuin_class_III	UniProtKB/TrEMBL
	Ssirtuin_cat_dom	UniProtKB/TrEMBL
KEGG Report	ssc:100125966	UniProtKB/TrEMBL
NCBI Gene	SIRT5	ENTREZGENE
PANTHER	NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL	UniProtKB/TrEMBL
	NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED	UniProtKB/TrEMBL
Pfam	SIR2	UniProtKB/TrEMBL
PROSITE	SIRTUIN	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52467	UniProtKB/TrEMBL
UniProt	A0A287AF07_PIG	UniProtKB/TrEMBL
	A0A480MQ13_PIG	UniProtKB/TrEMBL
	A0A4X1VJI2	ENTREZGENE
	A0A4X1VJJ7_PIG	UniProtKB/TrEMBL
	A0A4X1VJK2_PIG	UniProtKB/TrEMBL
	A0A5G2RB79_PIG	UniProtKB/TrEMBL
	A0A8D0I0F6_PIG	UniProtKB/TrEMBL
	A0A8D0NVT8_PIG	UniProtKB/TrEMBL
	A0A8D1AB22_PIG	UniProtKB/TrEMBL
	A0A8D1C148_PIG	UniProtKB/TrEMBL
	A0A8D1CWG5_PIG	UniProtKB/TrEMBL
	A0A8D1I6P1	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D1K297_PIG	UniProtKB/TrEMBL
	A0A8D1K5F6_PIG	UniProtKB/TrEMBL
	A0A8D1LE60_PIG	UniProtKB/TrEMBL
	A0A8D1LEN0_PIG	UniProtKB/TrEMBL
	A0A8D1LEN2_PIG	UniProtKB/TrEMBL
	A0A8D1SFF9_PIG	UniProtKB/TrEMBL
	A0A8D1SXL0_PIG	UniProtKB/TrEMBL
	A0A8D1Y7B2_PIG	UniProtKB/TrEMBL
	A0A8D1Y9L2_PIG	UniProtKB/TrEMBL
	A0A8W4F8P2_PIG	UniProtKB/TrEMBL
	A7XXV9	ENTREZGENE, UniProtKB/TrEMBL
	B0FWP7	ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary	A0A4X1VJI2	UniProtKB/TrEMBL
VGNC ID	VGNC:92888	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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RGD Manual Annotations