Shld2 (shieldin complex subunit 2) - Rat Genome Database

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Gene: Shld2 (shieldin complex subunit 2) Mus musculus
Analyze
Symbol: Shld2
Name: shieldin complex subunit 2
RGD ID: 1320663
MGI Page MGI
Description: Predicted to be involved in negative regulation of double-strand break repair via homologous recombination; positive regulation of double-strand break repair via nonhomologous end joining; and positive regulation of isotype switching. Predicted to act upstream of or within DNA repair. Predicted to be located in actin cytoskeleton; chromosome; and nucleoplasm. Predicted to be active in nucleus and site of double-strand break. Orthologous to human SHLD2 (shieldin complex subunit 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 3110001K24Rik; Fam3; Fam35a; family with sequence similarity 35, member A; hypothetical protein LOC75698; RINN1-REV7-interacting novel NHEJ regulator 2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391433,958,905 - 34,032,528 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1433,958,990 - 34,032,450 (-)EnsemblGRCm39 Ensembl
GRCm381434,236,948 - 34,310,651 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1434,237,033 - 34,310,493 (-)EnsemblGRCm38mm10GRCm38
MGSCv371435,050,219 - 35,123,689 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361433,066,133 - 33,139,458 (-)NCBIMGSCv36mm8
Celera1430,499,098 - 30,576,001 (-)NCBICelera
Cytogenetic Map14BNCBI
cM Map1420.8NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11544199   PMID:12226475   PMID:12466851   PMID:12477932   PMID:14610273   PMID:16141072   PMID:16141073  
PMID:17967808   PMID:18799693   PMID:21267068   PMID:21873635   PMID:29656893   PMID:35027730  


Genomics

Comparative Map Data
Shld2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391433,958,905 - 34,032,528 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1433,958,990 - 34,032,450 (-)EnsemblGRCm39 Ensembl
GRCm381434,236,948 - 34,310,651 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1434,237,033 - 34,310,493 (-)EnsemblGRCm38mm10GRCm38
MGSCv371435,050,219 - 35,123,689 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361433,066,133 - 33,139,458 (-)NCBIMGSCv36mm8
Celera1430,499,098 - 30,576,001 (-)NCBICelera
Cytogenetic Map14BNCBI
cM Map1420.8NCBI
SHLD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381087,094,473 - 87,191,465 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1087,094,161 - 87,191,465 (+)EnsemblGRCh38hg38GRCh38
GRCh371088,854,963 - 88,951,222 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361088,844,933 - 88,941,202 (+)NCBINCBI36Build 36hg18NCBI36
Build 341088,844,932 - 88,941,200NCBI
Cytogenetic Map10q23.2NCBI
HuRef1082,778,394 - 82,789,042 (+)NCBIHuRef
CHM1_11089,136,724 - 89,232,977 (+)NCBICHM1_1
T2T-CHM13v2.01087,978,839 - 88,075,088 (+)NCBIT2T-CHM13v2.0
Shld2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8169,554,921 - 9,646,186 (-)NCBIGRCr8
mRatBN7.2169,544,940 - 9,640,323 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl169,548,660 - 9,639,965 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx169,562,132 - 9,660,662 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01610,706,838 - 10,805,376 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0169,557,197 - 9,655,744 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01610,570,307 - 10,661,528 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1610,570,314 - 10,661,528 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0168,888,929 - 8,979,969 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4169,868,212 - 9,965,225 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera165,576,833 - 5,667,636 (+)NCBICelera
Cytogenetic Map16p15NCBI
Shld2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555106,075,510 - 6,114,898 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555106,021,477 - 6,114,745 (+)NCBIChiLan1.0ChiLan1.0
LOC103784056
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2859,311,152 - 59,353,528 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11059,316,469 - 59,359,047 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01043,572,547 - 43,624,201 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11487,923,049 - 87,928,101 (+)NCBIpanpan1.1PanPan1.1panPan2
SHLD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1434,665,111 - 34,740,645 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl434,688,245 - 34,763,705 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha434,654,858 - 34,732,283 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0435,023,800 - 35,101,252 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1434,869,031 - 34,946,347 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0435,038,013 - 35,115,455 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0435,544,430 - 35,621,946 (+)NCBIUU_Cfam_GSD_1.0
Shld2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721343,682,657 - 43,768,173 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366015,315,261 - 5,396,301 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366015,315,297 - 5,400,752 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SHLD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1488,005,611 - 88,121,352 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11488,005,599 - 88,121,155 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21495,538,054 - 95,600,923 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SHLD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1944,565,105 - 44,652,926 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl944,564,792 - 44,605,562 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660484,377,310 - 4,464,557 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Shld2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462484120,431 - 133,163 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462484121,077 - 133,155 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Shld2
2452 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:116
Count of miRNA genes:106
Interacting mature miRNAs:110
Transcripts:ENSMUST00000111917
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301991Wta3_mweight adult 3 (mouse)Not determined14388747337887650Mouse
4141550Dbm3_mdiabetes modifier 3 (mouse)Not determined514347339143596Mouse
4141864Mrdq4_mmodifier of retinal degeneration QTL 4 (mouse)Not determined992324548765082Mouse
1300779Dyscalc4_mdystrophic cardiac calcinosis 4 (mouse)Not determined141221287146213007Mouse
27226748Femd8_mfemur midshaft diameter 8, 10 week (mouse)141376927346737457Mouse
27226752Femd4_mfemur midshaft diameter 4, 5 week (mouse)141376927347237457Mouse
1300544Hypn_mhyperinsulinemia (mouse)Not determined141516061649160765Mouse
1301372Sluc13_msusceptibility to lung cancer 13 (mouse)Not determined141882760452827726Mouse
1357589Kdnw2_mkidney weight 2 (mouse)Not determined1420887473121269804Mouse
1357527Epfpq1_mepididymal fat percentage QTL 1 (mouse)Not determined142106245071885801Mouse
14746973Manh76_mmandible shape 76 (mouse)142228721756287217Mouse
4142485Modor2_mmodifier of ocular retardation 2 (mouse)Not determined142492624858179769Mouse
13506929Recrq10_mrecombination rate in male meiosis QTL 10 (mouse)142792195761137449Mouse
10043886Cia49_mcollagen induced arthritis QTL 49 (mouse)Not determined142999699463997133Mouse
27226775Tibl7_mtibia length 7, 5 week (mouse)143032195748837457Mouse
27226744Metcl6_mmetatarsal-calcaneal length 6, 5 week (mouse)143032195752937457Mouse
27226774Tibl15_mtibia length 15, 10 week (mouse)143032195787937436Mouse
1300909Ath13_matherosclerosis 13 (mouse)Not determined143033525064335381Mouse
1300998Cia17_mcollagen induced arthritis 17 (mouse)Not determined143033525064335381Mouse
27226737Metcl12_mmetatarsal-calcaneal length 12, 10 week (mouse)143322195759437449Mouse
14696688Rfq2_mrearing frequency QTL 2, males (mouse)143372195735721957Mouse

Markers in Region
UniSTS:237163  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381434,237,343 - 34,237,588UniSTSGRCm38
MGSCv371435,050,529 - 35,050,774UniSTSGRCm37
Celera1430,499,408 - 30,499,653UniSTS
Cytogenetic Map14BUniSTS
UniSTS:237165  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381434,268,151 - 34,268,428UniSTSGRCm38
MGSCv371435,081,337 - 35,081,614UniSTSGRCm37
Celera1430,530,635 - 30,530,912UniSTS
Cytogenetic Map14BUniSTS
GDB:277890  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381434,311,043 - 34,311,302UniSTSGRCm38
MGSCv371435,124,229 - 35,124,488UniSTSGRCm37
Cytogenetic Map14BUniSTS
cM Map1415.5UniSTS
D10Mit157.2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6D1UniSTS
Cytogenetic Map16B4UniSTS
Cytogenetic Map18E2UniSTS
Cytogenetic Map4C3UniSTS
Cytogenetic Map7B2UniSTS
Cytogenetic Map4D2.3UniSTS
Cytogenetic Map11E1UniSTS
Cytogenetic Map14E2.2UniSTS
Cytogenetic Map4C7UniSTS
Cytogenetic Map2H4UniSTS
Cytogenetic Map1FUniSTS
Cytogenetic Map6C3UniSTS
Cytogenetic Map11DUniSTS
Cytogenetic Map3G2UniSTS
Cytogenetic Map17A1UniSTS
Cytogenetic Map9F2UniSTS
Cytogenetic Map12F1UniSTS
Cytogenetic Map19C2UniSTS
Cytogenetic Map3BUniSTS
Cytogenetic Map8C1UniSTS
Cytogenetic Map18A2UniSTS
Cytogenetic Map3F2UniSTS
Cytogenetic Map14C3UniSTS
Cytogenetic Map8E1UniSTS
Cytogenetic Map8E2UniSTS
Cytogenetic Map5B1UniSTS
Cytogenetic Map18B1UniSTS
Cytogenetic Map9CUniSTS
Cytogenetic Map14C2UniSTS
Cytogenetic Map6A1UniSTS
Cytogenetic Map10B4UniSTS
Cytogenetic Map13D2.1UniSTS
Cytogenetic Map5E5UniSTS
Cytogenetic Map11B1.3UniSTS
Cytogenetic Map4D1UniSTS
Cytogenetic Map9A5.2UniSTS
Cytogenetic Map3F1UniSTS
Cytogenetic Map17E3UniSTS
Cytogenetic Map11B3UniSTS
Cytogenetic Map1H4UniSTS
Cytogenetic Map6A3UniSTS
Cytogenetic Map5E4-E5UniSTS
Cytogenetic Map15E1UniSTS
Cytogenetic Map13DUniSTS
Cytogenetic Map14BUniSTS
Cytogenetic Map14D1UniSTS
Cytogenetic Map7B4UniSTS
Cytogenetic Map8D3UniSTS
Cytogenetic MapXDUniSTS
Cytogenetic Map17A3.3UniSTS
Cytogenetic Map7E2UniSTS
Cytogenetic Map1H2.3UniSTS
Cytogenetic Map7A2UniSTS
Cytogenetic Map7F3UniSTS
Cytogenetic Map9F1UniSTS
Cytogenetic Map10C1UniSTS
Cytogenetic Map4E2UniSTS
Cytogenetic Map16A1UniSTS
Cytogenetic Map8B3.3UniSTS
Cytogenetic Map8D2UniSTS
Cytogenetic Map3DUniSTS
Cytogenetic Map15D2UniSTS
Cytogenetic Map17B1UniSTS
Cytogenetic Map7A3UniSTS
Cytogenetic Map15F1UniSTS
Cytogenetic Map16B2UniSTS
Cytogenetic Map7CUniSTS
Cytogenetic Map3F2.1UniSTS
Cytogenetic Map6F3UniSTS
Cytogenetic Map1C4UniSTS
Cytogenetic Map11E2UniSTS
Cytogenetic Map11B5UniSTS
Cytogenetic Map9F3UniSTS
Cytogenetic Map2BUniSTS
Cytogenetic Map13B3UniSTS
Cytogenetic Map9A4UniSTS
Cytogenetic Map5A3UniSTS
Cytogenetic Map2H1UniSTS
Cytogenetic Map16B1UniSTS
Cytogenetic Map1A5UniSTS
Cytogenetic Map11CUniSTS
Cytogenetic Map9E1UniSTS
Cytogenetic Map6G1UniSTS
Cytogenetic MapXA2UniSTS
Cytogenetic Map13B1UniSTS
Cytogenetic Map5E2UniSTS
Cytogenetic Map12C1UniSTS
Cytogenetic Map5FUniSTS
Cytogenetic Map4D3UniSTS
Cytogenetic Map10C2UniSTS
Cytogenetic Map9BUniSTS
Cytogenetic Map5G2UniSTS
Cytogenetic Map7F1UniSTS
Cytogenetic Map12C3UniSTS
Cytogenetic Map10A4UniSTS
Cytogenetic Map8A2UniSTS
Cytogenetic Map18A1UniSTS
Cytogenetic Map12A1.1UniSTS
Cytogenetic Map1C2UniSTS
Cytogenetic Map11B2UniSTS
Cytogenetic Map6E3UniSTS
Cytogenetic Map5C3.3UniSTS
Cytogenetic Map1BUniSTS
Cytogenetic Map17A3.1UniSTS
Cytogenetic Map7A1UniSTS
Cytogenetic Map2E5UniSTS
Cytogenetic Map11A1UniSTS
Cytogenetic Map4B1UniSTS
Cytogenetic Map15A2UniSTS
Cytogenetic Map8C3UniSTS
Cytogenetic Map2A3UniSTS
Cytogenetic Map5G3UniSTS
Cytogenetic Map4A3UniSTS
Cytogenetic Map2H3UniSTS
Cytogenetic Map8A1UniSTS
Cytogenetic Map8A1.1UniSTS
Cytogenetic Map16A3UniSTS
Cytogenetic Map10B1UniSTS
Cytogenetic Map19AUniSTS
Cytogenetic Map10A1UniSTS
Cytogenetic Map13D1UniSTS
Cytogenetic Map4A1UniSTS
Cytogenetic Map9A3UniSTS
Cytogenetic Map17CUniSTS
Cytogenetic Map1DUniSTS
Cytogenetic Map5E3UniSTS
Cytogenetic Map15D3UniSTS
Cytogenetic Map2H2UniSTS
Cytogenetic Map7D3UniSTS
Cytogenetic Map2A1UniSTS
Cytogenetic Map14C1UniSTS
Cytogenetic Map14E5UniSTS
Cytogenetic Map10CUniSTS
Cytogenetic Map18B2UniSTS
Cytogenetic Map2F1UniSTS
Cytogenetic Map10D3UniSTS
Cytogenetic Map17A2UniSTS
Cytogenetic Map2C3UniSTS
Cytogenetic Map1C3UniSTS
Cytogenetic Map17B2UniSTS
Cytogenetic Map5B2UniSTS
Cytogenetic Map5G1UniSTS
Cytogenetic Map4C6UniSTS
Cytogenetic Map13C3UniSTS
Cytogenetic Map2E1UniSTS
Cytogenetic Map17A3.2-A3.3UniSTS
Cytogenetic Map19C3UniSTS
Cytogenetic Map7E3UniSTS
Cytogenetic Map13C1UniSTS
Cytogenetic Map9E3.1UniSTS
Cytogenetic Map15E3UniSTS
Cytogenetic Map6B1UniSTS
Cytogenetic MapXE3UniSTS
Cytogenetic Map4C4UniSTS
Cytogenetic Map3E3UniSTS
Cytogenetic Map11A4UniSTS
Cytogenetic Map4C5UniSTS
Cytogenetic Map18B3UniSTS
Cytogenetic Map9A2UniSTS
Cytogenetic Map7E1UniSTS
Cytogenetic Map5D-E1UniSTS
Cytogenetic Map5B3UniSTS
Cytogenetic Map13A2-A3UniSTS
Cytogenetic Map5A2UniSTS
Cytogenetic Map4B3UniSTS
Cytogenetic Map1E4UniSTS
Cytogenetic Map17E4UniSTS
Cytogenetic Map1G2UniSTS
Cytogenetic Map15B3.1UniSTS
Cytogenetic Map12EUniSTS
Cytogenetic MapXA5UniSTS
Cytogenetic Map6A3.3UniSTS
Cytogenetic Map6G3UniSTS
Cytogenetic Map6F2UniSTS
Cytogenetic Map5C1UniSTS
Cytogenetic Map4D2.1UniSTS
Cytogenetic Map4A5UniSTS
Cytogenetic Map3F2.2UniSTS
Cytogenetic Map1E3-E4UniSTS
Cytogenetic Map9F1-F3UniSTS
Cytogenetic Map1C1.1UniSTS
Cytogenetic Map14D2UniSTS
Cytogenetic Map12A2UniSTS
Cytogenetic Map17A3-BUniSTS
Cytogenetic Map7F5UniSTS
Cytogenetic Map14A3UniSTS
Cytogenetic Map5G1.1UniSTS
Cytogenetic MapXF2-F4UniSTS
Cytogenetic Map7D2UniSTS
Cytogenetic Map2F3UniSTS
Cytogenetic Map10A3UniSTS
Cytogenetic MapXA7.3UniSTS
Cytogenetic Map9F1-F2UniSTS
Cytogenetic Map13A3.2UniSTS
Cytogenetic Map10A2UniSTS
Cytogenetic Map1C1UniSTS
Cytogenetic Map1A1UniSTS
Cytogenetic Map12D3UniSTS
Cytogenetic Map1A3-A5UniSTS
Cytogenetic Map2A2UniSTS
Cytogenetic Map3A1UniSTS
Cytogenetic MapXA3.3UniSTS
Cytogenetic Map16A-B1UniSTS
Cytogenetic Map1D2.3UniSTS
Cytogenetic Map6B2.3UniSTS
Cytogenetic Map2G3UniSTS
Cytogenetic MapXA2-A3.1UniSTS
Cytogenetic Map9A5.3UniSTS
Cytogenetic Map14A2-BUniSTS
Cytogenetic Map8E1-E2UniSTS
Cytogenetic Map8A3UniSTS
Cytogenetic Map1G3-H1UniSTS
Cytogenetic Map8B3-C1UniSTS
Cytogenetic Map19C1UniSTS
Cytogenetic Map8C5UniSTS
Cytogenetic Map8A4UniSTS
Cytogenetic Map15F3UniSTS
Cytogenetic Map14E4UniSTS
Cytogenetic Map4D2.2UniSTS
Cytogenetic MapXF5UniSTS
cM Map1040.0UniSTS
Whitehead Genetic1033.9UniSTS
D16Mgh3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381434,309,456 - 34,309,647UniSTSGRCm38
MGSCv371435,122,642 - 35,122,833UniSTSGRCm37
Celera1430,574,914 - 30,575,105UniSTS
Cytogenetic Map14BUniSTS
cM Map1415.5UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001360074 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_029389 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_153399 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006519645 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006519646 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006519648 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006519650 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006519651 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006519652 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011245216 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011245218 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017316219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001781163 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC154738 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC160930 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI451789 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK013957 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK081061 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK149442 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK162134 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC144822 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE630700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE648821 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE848901 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BF467362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ829235 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU756157 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD547520 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466573 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000111917   ⟹   ENSMUSP00000107548
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1433,958,990 - 34,032,323 (-)Ensembl
GRCm38.p6 Ensembl1434,237,033 - 34,310,366 (-)Ensembl
RefSeq Acc Id: ENSMUST00000227006   ⟹   ENSMUSP00000154637
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1433,990,680 - 33,996,216 (-)Ensembl
GRCm38.p6 Ensembl1434,268,723 - 34,274,259 (-)Ensembl
RefSeq Acc Id: ENSMUST00000227375   ⟹   ENSMUSP00000154555
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1433,990,518 - 34,032,450 (-)Ensembl
GRCm38.p6 Ensembl1434,268,561 - 34,310,493 (-)Ensembl
RefSeq Acc Id: ENSMUST00000228132
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1433,995,446 - 34,031,422 (-)Ensembl
GRCm38.p6 Ensembl1434,273,489 - 34,309,465 (-)Ensembl
RefSeq Acc Id: ENSMUST00000228337   ⟹   ENSMUSP00000153771
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1433,990,562 - 34,019,212 (-)Ensembl
GRCm38.p6 Ensembl1434,268,605 - 34,297,255 (-)Ensembl
RefSeq Acc Id: ENSMUST00000228626   ⟹   ENSMUSP00000154080
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1433,988,078 - 34,009,316 (-)Ensembl
GRCm38.p6 Ensembl1434,266,121 - 34,287,359 (-)Ensembl
RefSeq Acc Id: ENSMUST00000228704   ⟹   ENSMUSP00000154214
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1433,963,261 - 34,032,342 (-)Ensembl
GRCm38.p6 Ensembl1434,241,304 - 34,310,385 (-)Ensembl
RefSeq Acc Id: NM_001360074   ⟹   NP_001347003
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391433,958,990 - 34,032,474 (-)NCBI
GRCm381434,237,033 - 34,310,517 (-)NCBI
Sequence:
RefSeq Acc Id: NM_029389   ⟹   NP_083665
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391433,958,990 - 34,032,474 (-)NCBI
GRCm381434,237,033 - 34,310,517 (-)NCBI
MGSCv371435,050,219 - 35,123,689 (-)RGD
Celera1430,499,098 - 30,576,001 (-)RGD
cM Map14 ENTREZGENE
Sequence:
RefSeq Acc Id: NR_153399
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391433,958,990 - 34,032,474 (-)NCBI
GRCm381434,237,033 - 34,310,517 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006519645   ⟹   XP_006519708
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391433,958,990 - 33,996,986 (-)NCBI
GRCm381434,237,292 - 34,275,032 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006519646   ⟹   XP_006519709
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391433,958,990 - 34,032,210 (-)NCBI
GRCm381434,237,038 - 34,310,253 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006519648   ⟹   XP_006519711
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391433,958,990 - 33,996,986 (-)NCBI
GRCm381434,237,292 - 34,275,032 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006519650   ⟹   XP_006519713
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391433,958,905 - 33,974,591 (-)NCBI
GRCm381434,236,948 - 34,252,628 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006519651   ⟹   XP_006519714
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391433,958,905 - 33,974,584 (-)NCBI
GRCm381434,236,948 - 34,252,622 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006519652   ⟹   XP_006519715
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391433,958,905 - 34,032,528 (-)NCBI
GRCm381434,236,948 - 34,310,651 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011245216   ⟹   XP_011243518
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391433,958,990 - 34,032,210 (-)NCBI
GRCm381434,237,292 - 34,310,253 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011245218   ⟹   XP_011243520
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391433,958,905 - 34,032,210 (-)NCBI
GRCm381434,236,948 - 34,310,651 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017316219   ⟹   XP_017171708
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391433,958,905 - 34,032,526 (-)NCBI
GRCm381434,236,948 - 34,310,651 (-)NCBI
Sequence:
RefSeq Acc Id: XR_001781163
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391433,958,905 - 34,032,528 (-)NCBI
GRCm381434,236,948 - 34,310,651 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_083665   ⟸   NM_029389
- UniProtKB: E9Q8K3 (UniProtKB/Swiss-Prot),   Q3UEN2 (UniProtKB/Swiss-Prot),   B7ZMV3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006519715   ⟸   XM_006519652
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006519709   ⟸   XM_006519646
- Peptide Label: isoform X1
- UniProtKB: E9Q8K3 (UniProtKB/Swiss-Prot),   Q3UEN2 (UniProtKB/Swiss-Prot),   B7ZMV3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006519711   ⟸   XM_006519648
- Peptide Label: isoform X1
- UniProtKB: E9Q8K3 (UniProtKB/Swiss-Prot),   Q3UEN2 (UniProtKB/Swiss-Prot),   B7ZMV3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006519708   ⟸   XM_006519645
- Peptide Label: isoform X1
- UniProtKB: E9Q8K3 (UniProtKB/Swiss-Prot),   Q3UEN2 (UniProtKB/Swiss-Prot),   B7ZMV3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006519713   ⟸   XM_006519650
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006519714   ⟸   XM_006519651
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_011243520   ⟸   XM_011245218
- Peptide Label: isoform X2
- UniProtKB: B7ZMV3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011243518   ⟸   XM_011245216
- Peptide Label: isoform X1
- UniProtKB: E9Q8K3 (UniProtKB/Swiss-Prot),   Q3UEN2 (UniProtKB/Swiss-Prot),   B7ZMV3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017171708   ⟸   XM_017316219
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: NP_001347003   ⟸   NM_001360074
- UniProtKB: Q3UEN2 (UniProtKB/Swiss-Prot),   E9Q8K3 (UniProtKB/Swiss-Prot),   B7ZMV3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSMUSP00000107548   ⟸   ENSMUST00000111917
RefSeq Acc Id: ENSMUSP00000153771   ⟸   ENSMUST00000228337
RefSeq Acc Id: ENSMUSP00000154555   ⟸   ENSMUST00000227375
RefSeq Acc Id: ENSMUSP00000154637   ⟸   ENSMUST00000227006
RefSeq Acc Id: ENSMUSP00000154214   ⟸   ENSMUST00000228704
RefSeq Acc Id: ENSMUSP00000154080   ⟸   ENSMUST00000228626
Protein Domains
Shieldin complex subunit 2 C-terminal   Shieldin complex subunit 2 first OB fold

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q3UEN2-F1-model_v2 AlphaFold Q3UEN2 1-891 view protein structure

Promoters
RGD ID:8681926
Promoter ID:EPDNEW_M18994
Type:initiation region
Name:Fam35a_1
Description:Mus musculus family with sequence similarity 35, member A , transcriptvariant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381434,310,554 - 34,310,614EPDNEW
RGD ID:6824956
Promoter ID:MM_KWN:16204
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000035262,   NM_029389,   OTTMUST00000076096,   UC007TAR.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361435,122,966 - 35,125,022 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1922948 AgrOrtholog
Ensembl Genes ENSMUSG00000041471 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000111917 ENTREZGENE
  ENSMUST00000111917.3 UniProtKB/Swiss-Prot
  ENSMUST00000227006.2 UniProtKB/TrEMBL
  ENSMUST00000227375.2 UniProtKB/TrEMBL
  ENSMUST00000228337.2 UniProtKB/TrEMBL
  ENSMUST00000228626.2 UniProtKB/TrEMBL
  ENSMUST00000228704.2 UniProtKB/TrEMBL
InterPro FAM35A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FAM35A_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SHLD2_OB1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:75698 UniProtKB/Swiss-Prot
MGD MGI:1922948 ENTREZGENE
NCBI Gene 75698 ENTREZGENE
PANTHER PTHR14495 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SHIELDIN COMPLEX SUBUNIT 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam FAM35_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SHLD2_OB1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Shld2 PhenoGen
UniProt A0A2I3BPG1_MOUSE UniProtKB/TrEMBL
  A0A2I3BQ88_MOUSE UniProtKB/TrEMBL
  A0A2I3BQV1_MOUSE UniProtKB/TrEMBL
  A0A2I3BRM7_MOUSE UniProtKB/TrEMBL
  B7ZMV3 ENTREZGENE, UniProtKB/TrEMBL
  E9Q8K3 ENTREZGENE
  Q3UEN2 ENTREZGENE
  Q9CRX3_MOUSE UniProtKB/TrEMBL
  SHLD2_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary E9Q8K3 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-06-05 Shld2  shieldin complex subunit 2  Fam35a  family with sequence similarity 35, member A  Symbol and/or name change 5135510 APPROVED