SHLD2 (shieldin complex subunit 2)

Gene: SHLD2 (shieldin complex subunit 2) Chlorocebus sabaeus

Analyze

Symbol:

SHLD2

Name:

shieldin complex subunit 2

RGD ID:

18532559

Description:

INVOLVED IN negative regulation of double-strand break repair via homologous recombination (inferred); positive regulation of double-strand break repair via nonhomologous end joining (inferred); positive regulation of isotype switching (inferred); ASSOCIATED WITH diabetes mellitus (ortholog); familial hyperinsulinemic hypoglycemia 6 (ortholog); genetic disease (ortholog); FOUND IN actin cytoskeleton (inferred); chromosome (inferred); nucleoplasm (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

FAM35A; family with sequence similarity 35 member A; protein FAM35A

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	9	44,565,105 - 44,652,926 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	9	44,564,792 - 44,605,562 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666048	4,377,310 - 4,464,557 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

diabetes mellitus (ISO)

familial hyperinsulinemic hypoglycemia 6 (ISO)

genetic disease (ISO)

hyperinsulinism (ISO)

juvenile polyposis syndrome (ISO)

PTEN hamartoma tumor syndrome (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of double-strand break repair via homologous recombination (IEA)

positive regulation of double-strand break repair via nonhomologous end joining (IEA)

positive regulation of isotype switching (IEA)

regulation of double-strand break repair via homologous recombination (IEA)

Cellular Component

actin cytoskeleton (IEA)

chromosome (IEA)

nucleoplasm (IEA)

nucleus (IEA)

site of double-strand break (IEA)

Molecular Function

protein binding (ISO)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

SHLD2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	9	44,565,105 - 44,652,926 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	9	44,564,792 - 44,605,562 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666048	4,377,310 - 4,464,557 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

SHLD2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	10	87,094,473 - 87,191,465 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	10	87,094,161 - 87,191,465 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	10	88,854,963 - 88,951,222 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	88,844,933 - 88,941,202 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	10	88,844,932 - 88,941,200	NCBI
Cytogenetic Map	10	q23.2	NCBI
HuRef	10	82,778,394 - 82,789,042 (+)	NCBI		HuRef
CHM1_1	10	89,136,724 - 89,232,977 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	10	87,978,839 - 88,075,088 (+)	NCBI		T2T-CHM13v2.0

Shld2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	33,958,905 - 34,032,528 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	33,958,990 - 34,032,450 (-)	Ensembl		GRCm39 Ensembl
GRCm38	14	34,236,948 - 34,310,651 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	34,237,033 - 34,310,493 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	14	35,050,219 - 35,123,689 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	14	33,066,133 - 33,139,458 (-)	NCBI		MGSCv36	mm8
Celera	14	30,499,098 - 30,576,001 (-)	NCBI		Celera
Cytogenetic Map	14	B	NCBI
cM Map	14	20.8	NCBI

Shld2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	9,554,921 - 9,646,186 (-)	NCBI		GRCr8
mRatBN7.2	16	9,544,940 - 9,640,323 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	9,548,660 - 9,639,965 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	16	9,562,132 - 9,660,662 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	10,706,838 - 10,805,376 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	9,557,197 - 9,655,744 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	10,570,307 - 10,661,528 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	10,570,314 - 10,661,528 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	16	8,888,929 - 8,979,969 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	16	9,868,212 - 9,965,225 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	16	5,576,833 - 5,667,636 (+)	NCBI		Celera
Cytogenetic Map	16	p15	NCBI

Shld2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955510	6,075,510 - 6,114,898 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955510	6,021,477 - 6,114,745 (+)	NCBI	ChiLan1.0	ChiLan1.0

LOC103784056
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	8	59,311,152 - 59,353,528 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	10	59,316,469 - 59,359,047 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	10	43,572,547 - 43,624,201 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	87,923,049 - 87,928,101 (+)	NCBI	panpan1.1	PanPan1.1	panPan2

SHLD2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	4	34,665,111 - 34,740,645 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	4	34,688,245 - 34,763,705 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	4	34,654,858 - 34,732,283 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	4	35,023,800 - 35,101,252 (+)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	4	34,869,031 - 34,946,347 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	4	35,038,013 - 35,115,455 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	4	35,544,430 - 35,621,946 (+)	NCBI		UU_Cfam_GSD_1.0

Shld2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	43,682,657 - 43,768,173 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936601	5,315,261 - 5,396,301 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936601	5,315,297 - 5,400,752 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SHLD2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	88,005,611 - 88,121,352 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	88,005,599 - 88,121,155 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	95,538,054 - 95,600,923 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Shld2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624841	20,431 - 133,163 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624841	21,077 - 133,155 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	endocrine system	hemolymphoid system	nervous system
High
Medium	36		32
Low		20	28
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_007962673	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007962674	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007962675	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007962676	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007962677	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007962678	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007962679	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007962681	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007962682	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038008940	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038008941	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038008942	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038008944	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038008945	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038008946	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038008947	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000016	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCSAT00000007963 ⟹ ENSCSAP00000006121

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	9	44,564,792 - 44,605,562 (-)	Ensembl

RefSeq Acc Id:

XM_007962675 ⟹ XP_007960866

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	9	44,565,105 - 44,629,078 (-)	NCBI
Vero_WHO_p1.0	NW_023666048	4,377,310 - 4,441,297 (-)	NCBI

Sequence:

show sequence

ACTCCTGACCTCCAGTGATCTGCCTGCCTTGGTTTCCCAAAGTTCTGGGATTATAGGCATGAGC
CACTGCACCTGGCCAAAAGTGGTATTTTCTGTTGCATTTGAGGTAAAAGAAATTGATGGGCTTG
TTATTGCATTTGGTGTGGCTTTTTTTTTTTTTCTTGTTGTGTTTCTCCACTGACTGTCAAAACA
AACAAACAAACAAACAAAAAATGCTACATTCATGAGTGCCACGAGAGAGATTCCCGATTCTCGA
GTGCTACAAGAGACCAAGAAATCATGAGTGGAGGATCTCAAGTCCACATTTTTTGGGGTGCTCC
AGTTGCTCCACTGAAAATGACAGTATCACAAGACACAGTTTCTTTAATGTCCGTTGCTGACCCC
TGGAAAAAAATTCAGCTTTTATGCAGTCAACATTCTTTATATCTGAAGGATGAAAAACCGCACA
ACAATCTTGAAAACTGTGAAGTCCCAGAATCTATTGGTTCTCCAGATCTTCTTAGTGGTCCTTT
CTTAACAAACTGTATGAATAGACATGTTCATGTGAAAGATGACTTTGTACATTCTGTTTCTGAA
ACACAGAATATAGAGTCCCAGAAGATTCACTCCTCTAGACTGAGTGATGTAACTAGCTCTAATA
TGCAAATATGTGGATTTAAAAGCGCAGTTCCGCATTTAACTGAAGAAGAAAAGTATCAAAAGCT
TCTCAGTGAAAATAAAATTATAGATGAACAGCCTAAACATCAGTCAGACATATGTGGTCAGAAC
TTTAACACAGATTTGTGTCAGTTAAGCCATAAGTGTGCAGCTGTGTTGGATTTGGTGTGTAGTA
CTGAACAAATTAATATAGGGCCTGAAGTGGTACAAAGAGAGTGTGTGCCGACAGAATATCATGA
AATACAAAACCAGTGTTTGGGATTATTTTCCTCGAACGCAGTATATAAGCCAAGGTCTGAAGGA
GCAGTTAGGAAGGTCTCAGACCTTAAAATATCAACTGATACTGAATTTCTCAGTATAATTACCT
CCAGCCAGGTTGCTTTTTTAGCTCAAAAGAAAGATAAAGGGCGGAGTCCTATAAATAAAGGGAA
TGCAAACATGGAGACTGAACCAAAGGCAAGTTACGGGGAGATAAGAATACCTGAAGAGAATTCA
ATTCAGCTTGATGATTTTACAGATGCATATGAAAGTGGACAAAACCAAGCATATTCTCTTGAAC
TTTTTAGTCCTGTTTGTCCTAAAACAGAAAATAGCCACATTCACATAAACTCTGATAAAGGTCT
TGAAGAAAATACAGGATCTCAAGAACTTTTCAGTTCTGAAGATGAACTGCCACCAAATGAGATA
CGTATTGAGTTGTGTAGCTCAGGAATACTGTGTTCCCAGCTAAATACCTTTCACAGAAGTGCTA
TTAAAAGAAGCTGCATCTCTGAAGATAAGGTGGGCCAGTCTGAAGCTCTGTCTCGAGTCCTTCA
AGTAGCTAAGAAAATGAAGTTGATTTCTAATGAAGGAGATTCTGCTGTAGAAGTGGATCAGAGG
AATGTGTCTGAATTTAAGGGTATTAAAAAAACGTCATTAATAAAAAACTGTGATTCTAAAAGCC
AGAAGTATAATTGTTTAGTCATGGTGCTATCTCCATGCCATGTGAAGGAAATAAACATAAAATT
CGGACCAAATTCTGGCTCTAAAGTGCCTTTAGCAACAGTTATAGTAATTGATCAATCAGAAACT
AAGAAGAAAGTTTTTCTGTGGAGGACTGCAGCATTTTGGGCATTTACAGTGTTTCTTGGAGATA
TAATTTTACTCACAGATGTTGTTATTCATGAGGACCAATGGGTTGGCGAGACAGTACTACAATC
AACATTTAGCAGTCAGTTATTAAATCTTGGGAGTTATTCATCTATTCAGCCTGAAGAATATTCC
AGTGTAGTTAGTAATGTTGTACTTCAAGACTTACTGGCATATGTGTCCTCAAAACATTCCTACC
TCAGAGATCTTCCTCCAAGGCAGCCTCAGAGGGTGAACAGTATAGACTTTGTAGAATTGGAGCA
CCTTCAGCCTGATGTATTAGTCCACGCAGTACTAAGAGTTGTTGATTTCACTGTACTTACAGAG
GCAGTATACAGTTATAGAGGACAGAAGCAGAAAAAAGTTATGTTAACAGTGGAACAGGCCCAAG
ACAAACATTATGTGCTTGTATTATGGGGTCCTGGAGCAGCCTGGTACCCTCAACTTCAAAGGAA
AAAAGGTTATATTTGGGAATTTAAATATCTTTTTGTTCAGCGCAATTACACACTAGAAAACCTA
GAGTTGCATACAACACCTTGGTCATCCTGTGAGTGCTTGTTTGATGATGATATAAGGGCAATTA
CATTTAAAGCAAAATTTCAAAAAAGTACACCCGCCTTTGTGAAGATATCAGACTTAGCAGCCCA
CCTAGAGGATAAGTGTTCAGGAGTGATTCTAATTAAAGCCCAGATTTCAGAGCTGGCATTTCCT
ACAGCAACTCAGAAGATAGCTCTAAATGCTCACAGTTCTCTGAAGAGTATTTTCTCTTCTCTTC
CCAACATCGTATATACTGGCTGCGCAAAATGTGGATTGGAACTAGAAACAGATGAGAACAGGAT
CTATAAACAGTGTTTTAGCTGCTTGCCATTTACTATGAAGAAAATACACTATAGGCCAGCCTTA
ATGACTGTAGTTGATGGAAGACATGATGTTTGCATCCGTGTAGAATCAAAGCTGATAGAGAAGA
TTCTTCTCAACATTTCTGCAGACTGCCTCAACAGAGTGATAGTTCCTTCCTCAGACATCACCTA
TGGGATGGTCGTGGCAGACCTGTTCCACTCCTTGCTGGCAGTCAACGCAGAACCTTGTGTATTG
AAGATTCAGAGCCTTTTTGTGTCAGATGAAAACAGCTATCCATTACAACAAGATTTCTCCCTCC
TGGATTTTTATCCTGACATTGTAAAGCATGGAGCCGATGCCCTTCTTTGTGGCCAGAGGAAGAA
ATTGTAGACATTTCAAGGAAGAAGTACTGAAATGATTTGTCTTTTGAAATAAATGAATGACAGG
ACTTTTGCTTTGGATTTTTTATTAAATATATTTTACGAAGAGAATTGCAGTAGATATATAAATT
AAAACTTTTTTCTAAGAAAATCCTGTGAGGTTTAAAAAGATTGTTTTTGTTTTTTTGGTTTCTT
CCTTTCTTCTGGAGAAATGATCTACCAGTCAAAGCAATATGTAGCCGATCCCTGGGAATTAAAG
GTTTGCCCATTTGTTCACTGTGTTTAGTCCCTGCTGCATTCCAGGCATTGTACTAAGTATGGGG
AACTACATGGAAGACAGTCCCTCAGAAACTGCTGCAGTGCTTTTGCTTATCCCTACCTAAAAAA
CCGTCAATGTGAAATCATTTCCTTGATTATAACTATACATGATAATGGATTAGTTTATATAAAC
CTATGTTTAGACAAGTTCAAAACAAGCGTGTCTTTCTATAAAAAGCTTTGAAAATGAAGGAAAT
GAGATCATGTTTCAATTTATTAAAGCGGAGAAGAGCGTTCTGTGGTTAGTTCGTGTCTAGGATT
TGAGTGCCTTACTGAATGTATTTACCAGCAAACATGTAGCAATCGGTTCTCTCATTGTGATGGT
AGAAGCTCATGTAAAATGGTAGTCATTAATGAGGAAGTATGGAGTGGTACTTATTCTGTAAGTT
CAGAGTATGCCAAGTGTTAATATATTATCATATTGCCTGAAAATAAATTTATGATGATATGAAC
AAGCTTA

hide sequence

RefSeq Acc Id:

XM_007962678 ⟹ XP_007960869

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	9	44,565,105 - 44,652,926 (-)	NCBI
Vero_WHO_p1.0	NW_023666048	4,377,310 - 4,464,540 (-)	NCBI

Sequence:

show sequence

GGGAGGGCTGGGGCGGGCCGGCGGGCGGCCGGATCTGCTCGCAGGCCGCACCCGCCTCCGGCTG
GGTGCTCAGAAATCATGAGTGGAGGATCTCAAGTCCACATTTTTTGGGGTGCTCCAGTTGCTCC
ACTGAAAATGACAGTATCACAAGACACAGTTTCTTTAATGTCCGTTGCTGACCCCTGGAAAAAA
ATTCAGCTTTTATGCAGTCAACATTCTTTATATCTGAAGGATGAAAAACCGCACAACAATCTTG
AAAACTGTGAAGTCCCAGAATCTATTGGTTCTCCAGATCTTCTTAGTGGTCCTTTCTTAACAAA
CTGTATGAATAGACATGTTCATGTGAAAGATGACTTTGTACATTCTGTTTCTGAAACACAGAAT
ATAGAGTCCCAGAAGATTCACTCCTCTAGACTGAGTGATGTAACTAGCTCTAATATGCAAATAT
GTGGATTTAAAAGCGCAGTTCCGCATTTAACTGAAGAAGAAAAGTATCAAAAGCTTCTCAGTGA
AAATAAAATTATAGATGAACAGCCTAAACATCAGTCAGACATATGTGGTCAGAACTTTAACACA
GATTTGTGTCAGTTAAGCCATAAGTGTGCAGCTGTGTTGGATTTGGTGTGTAGTACTGAACAAA
TTAATATAGGGCCTGAAGTGGTACAAAGAGAGTGTGTGCCGACAGAATATCATGAAATACAAAA
CCAGTGTTTGGGATTATTTTCCTCGAACGCAGTATATAAGCCAAGGTCTGAAGGAGCAGTTAGG
AAGGTCTCAGACCTTAAAATATCAACTGATACTGAATTTCTCAGTATAATTACCTCCAGCCAGG
TTGCTTTTTTAGCTCAAAAGAAAGATAAAGGGCGGAGTCCTATAAATAAAGGGAATGCAAACAT
GGAGACTGAACCAAAGGCAAGTTACGGGGAGATAAGAATACCTGAAGAGAATTCAATTCAGCTT
GATGATTTTACAGATGCATATGAAAGTGGACAAAACCAAGCATATTCTCTTGAACTTTTTAGTC
CTGTTTGTCCTAAAACAGAAAATAGCCACATTCACATAAACTCTGATAAAGGTCTTGAAGAAAA
TACAGGATCTCAAGAACTTTTCAGTTCTGAAGATGAACTGCCACCAAATGAGATACGTATTGAG
TTGTGTAGCTCAGGAATACTGTGTTCCCAGCTAAATACCTTTCACAGAAGTGCTATTAAAAGAA
GCTGCATCTCTGAAGATAAGGTGGGCCAGTCTGAAGCTCTGTCTCGAGTCCTTCAAGTAGCTAA
GAAAATGAAGTTGATTTCTAATGAAGGAGATTCTGCTGTAGAAGTGGATCAGAGGAATGTGTCT
GAATTTAAGGGTATTAAAAAAACGTCATTAATAAAAAACTGTGATTCTAAAAGCCAGAAGTATA
ATTGTTTAGTCATGGTGCTATCTCCATGCCATGTGAAGGAAATAAACATAAAATTCGGACCAAA
TTCTGGCTCTAAAGTGCCTTTAGCAACAGTTATAGTAATTGATCAATCAGAAACTAAGAAGAAA
GTTTTTCTGTGGAGGACTGCAGCATTTTGGGCATTTACAGTGTTTCTTGGAGATATAATTTTAC
TCACAGATGTTGTTATTCATGAGGACCAATGGGTTGGCGAGACAGTACTACAATCAACATTTAG
CAGTCAGTTATTAAATCTTGGGAGTTATTCATCTATTCAGCCTGAAGAATATTCCAGTGTAGTT
AGTAATGTTGTACTTCAAGACTTACTGGCATATGTGTCCTCAAAACATTCCTACCTCAGAGATC
TTCCTCCAAGGCAGCCTCAGAGGGTGAACAGTATAGACTTTGTAGAATTGGAGCACCTTCAGCC
TGATGTATTAGTCCACGCAGTACTAAGAGTTGTTGATTTCACTGTACTTACAGAGGCAGTATAC
AGTTATAGAGGACAGAAGCAGAAAAAAGTTATGTTAACAGTGGAACAGGCCCAAGACAAACATT
ATGTGCTTGTATTATGGGGTCCTGGAGCAGCCTGGTACCCTCAACTTCAAAGGAAAAAAGGTTA
TATTTGGGAATTTAAATATCTTTTTGTTCAGCGCAATTACACACTAGAAAACCTAGAGTTGCAT
ACAACACCTTGGTCATCCTGTGAGTGCTTGTTTGATGATGATATAAGGGCAATTACATTTAAAG
CAAAATTTCAAAAAAGTACACCCGCCTTTGTGAAGATATCAGACTTAGCAGCCCACCTAGAGGA
TAAGTGTTCAGGAGTGATTCTAATTAAAGCCCAGATTTCAGAGCTGGCATTTCCTACAGCAACT
CAGAAGATAGCTCTAAATGCTCACAGTTCTCTGAAGAGTATTTTCTCTTCTCTTCCCAACATCG
TATATACTGGCTGCGCAAAATGTGGATTGGAACTAGAAACAGATGAGAACAGGATCTATAAACA
GTGTTTTAGCTGCTTGCCATTTACTATGAAGAAAATACACTATAGGCCAGCCTTAATGACTGTA
GTTGATGGAAGACATGATGTTTGCATCCGTGTAGAATCAAAGCTGATAGAGAAGATTCTTCTCA
ACATTTCTGCAGACTGCCTCAACAGAGTGATAGTTCCTTCCTCAGACATCACCTATGGGATGGT
CGTGGCAGACCTGTTCCACTCCTTGCTGGCAGTCAACGCAGAACCTTGTGTATTGAAGATTCAG
AGCCTTTTTGTGTCAGATGAAAACAGCTATCCATTACAACAAGATTTCTCCCTCCTGGATTTTT
ATCCTGACATTGTAAAGCATGGAGCCGATGCCCTTCTTTGTGGCCAGAGGAAGAAATTGTAGAC
ATTTCAAGGAAGAAGTACTGAAATGATTTGTCTTTTGAAATAAATGAATGACAGGACTTTTGCT
TTGGATTTTTTATTAAATATATTTTACGAAGAGAATTGCAGTAGATATATAAATTAAAACTTTT
TTCTAAGAAAATCCTGTGAGGTTTAAAAAGATTGTTTTTGTTTTTTTGGTTTCTTCCTTTCTTC
TGGAGAAATGATCTACCAGTCAAAGCAATATGTAGCCGATCCCTGGGAATTAAAGGTTTGCCCA
TTTGTTCACTGTGTTTAGTCCCTGCTGCATTCCAGGCATTGTACTAAGTATGGGGAACTACATG
GAAGACAGTCCCTCAGAAACTGCTGCAGTGCTTTTGCTTATCCCTACCTAAAAAACCGTCAATG
TGAAATCATTTCCTTGATTATAACTATACATGATAATGGATTAGTTTATATAAACCTATGTTTA
GACAAGTTCAAAACAAGCGTGTCTTTCTATAAAAAGCTTTGAAAATGAAGGAAATGAGATCATG
TTTCAATTTATTAAAGCGGAGAAGAGCGTTCTGTGGTTAGTTCGTGTCTAGGATTTGAGTGCCT
TACTGAATGTATTTACCAGCAAACATGTAGCAATCGGTTCTCTCATTGTGATGGTAGAAGCTCA
TGTAAAATGGTAGTCATTAATGAGGAAGTATGGAGTGGTACTTATTCTGTAAGTTCAGAGTATG
CCAAGTGTTAATATATTATCATATTGCCTGAAAATAAATTTATGATGATATGAACAAGCTTA

hide sequence

RefSeq Acc Id:

XM_007962679 ⟹ XP_007960870

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	9	44,565,105 - 44,600,114 (-)	NCBI
Vero_WHO_p1.0	NW_023666048	4,377,310 - 4,412,275 (-)	NCBI

Sequence:

show sequence

TACCTCGGCCTCCCAAAGTTCTGGGATTACAGGTGTGAGCCACCACACCCGGCCCAAACTGAAA
AATTTTAAGTAACAGATGTATTCCAGATCTTGTTGAATACCAACACAGTAGACAGTTTGCTATT
ATACTTCTAGCAATAGAATGAAGAGATGCCAAAAATAAGGATTACCTAAGGGAGACTACTGACT
AGAATTAGATGAAGACAGGGGACTTACCACTGGGAAACAACAGTGTTTAAAGGACAAACAGCAT
AAGAACTAGGAGCTGGGGTATGTCAGTGAGAGGGCAGGAAGGAGCCAGGAGGCCAGGGCAGGCT
ACCCATCCCCTCCATCCACTGCTAGTGATTACCATGTGACTAATCCAACATTGGCTTCAGAGTC
CTAGCTTTCAGAACGCTCTCCTTGAAATTTCTCATCTGTTCCTTTTTTCTGAAGAACATGCATC
CTGAATGTTGGATCATGAAAAGTCTTGAATGCTGTACTAGCTCTTCCTGGCTAGGCAGTGGGGA
GCCACTGTTTTTCAATGTTGTTATTCATGAGGACCAATGGGTTGGCGAGACAGTACTACAATCA
ACATTTAGCAGTCAGTTATTAAATCTTGGGAGTTATTCATCTATTCAGCCTGAAGAATATTCCA
GTGTAGTTAGTAATGTTGTACTTCAAGACTTACTGGCATATGTGTCCTCAAAACATTCCTACCT
CAGAGATCTTCCTCCAAGGCAGCCTCAGAGGGTGAACAGTATAGACTTTGTAGAATTGGAGCAC
CTTCAGCCTGATGTATTAGTCCACGCAGTACTAAGAGTTGTTGATTTCACTGTACTTACAGAGG
CAGTATACAGTTATAGAGGACAGAAGCAGAAAAAAGTTATGTTAACAGTGGAACAGGCCCAAGA
CAAACATTATGTGCTTGTATTATGGGGTCCTGGAGCAGCCTGGTACCCTCAACTTCAAAGGAAA
AAAGGTTATATTTGGGAATTTAAATATCTTTTTGTTCAGCGCAATTACACACTAGAAAACCTAG
AGTTGCATACAACACCTTGGTCATCCTGTGAGTGCTTGTTTGATGATGATATAAGGGCAATTAC
ATTTAAAGCAAAATTTCAAAAAAGTACACCCGCCTTTGTGAAGATATCAGACTTAGCAGCCCAC
CTAGAGGATAAGTGTTCAGGAGTGATTCTAATTAAAGCCCAGATTTCAGAGCTGGCATTTCCTA
CAGCAACTCAGAAGATAGCTCTAAATGCTCACAGTTCTCTGAAGAGTATTTTCTCTTCTCTTCC
CAACATCGTATATACTGGCTGCGCAAAATGTGGATTGGAACTAGAAACAGATGAGAACAGGATC
TATAAACAGTGTTTTAGCTGCTTGCCATTTACTATGAAGAAAATACACTATAGGCCAGCCTTAA
TGACTGTAGTTGATGGAAGACATGATGTTTGCATCCGTGTAGAATCAAAGCTGATAGAGAAGAT
TCTTCTCAACATTTCTGCAGACTGCCTCAACAGAGTGATAGTTCCTTCCTCAGACATCACCTAT
GGGATGGTCGTGGCAGACCTGTTCCACTCCTTGCTGGCAGTCAACGCAGAACCTTGTGTATTGA
AGATTCAGAGCCTTTTTGTGTCAGATGAAAACAGCTATCCATTACAACAAGATTTCTCCCTCCT
GGATTTTTATCCTGACATTGTAAAGCATGGAGCCGATGCCCTTCTTTGTGGCCAGAGGAAGAAA
TTGTAGACATTTCAAGGAAGAAGTACTGAAATGATTTGTCTTTTGAAATAAATGAATGACAGGA
CTTTTGCTTTGGATTTTTTATTAAATATATTTTACGAAGAGAATTGCAGTAGATATATAAATTA
AAACTTTTTTCTAAGAAAATCCTGTGAGGTTTAAAAAGATTGTTTTTGTTTTTTTGGTTTCTTC
CTTTCTTCTGGAGAAATGATCTACCAGTCAAAGCAATATGTAGCCGATCCCTGGGAATTAAAGG
TTTGCCCATTTGTTCACTGTGTTTAGTCCCTGCTGCATTCCAGGCATTGTACTAAGTATGGGGA
ACTACATGGAAGACAGTCCCTCAGAAACTGCTGCAGTGCTTTTGCTTATCCCTACCTAAAAAAC
CGTCAATGTGAAATCATTTCCTTGATTATAACTATACATGATAATGGATTAGTTTATATAAACC
TATGTTTAGACAAGTTCAAAACAAGCGTGTCTTTCTATAAAAAGCTTTGAAAATGAAGGAAATG
AGATCATGTTTCAATTTATTAAAGCGGAGAAGAGCGTTCTGTGGTTAGTTCGTGTCTAGGATTT
GAGTGCCTTACTGAATGTATTTACCAGCAAACATGTAGCAATCGGTTCTCTCATTGTGATGGTA
GAAGCTCATGTAAAATGGTAGTCATTAATGAGGAAGTATGGAGTGGTACTTATTCTGTAAGTTC
AGAGTATGCCAAGTGTTAATATATTATCATATTGCCTGAAAATAAATTTATGATGATATGAACA
AGCTTA

hide sequence

RefSeq Acc Id:

XM_007962682 ⟹ XP_007960873

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	9	44,565,105 - 44,652,913 (-)	NCBI
Vero_WHO_p1.0	NW_023666048	4,377,310 - 4,464,540 (-)	NCBI

Sequence:

show sequence

CGGGCCGGCGGGCGGCCGGATCTGCTCGCAGGCCGCACCCGCCTCCGGCTGGGTGCTCAGATGT
TGTTATTCATGAGGACCAATGGGTTGGCGAGACAGTACTACAATCAACATTTAGCAGTCAGTTA
TTAAATCTTGGGAGTTATTCATCTATTCAGCCTGAAGAATATTCCAGTGTAGTTAGTAATGTTG
TACTTCAAGACTTACTGGCATATGTGTCCTCAAAACATTCCTACCTCAGAGATCTTCCTCCAAG
GCAGCCTCAGAGGGTGAACAGTATAGACTTTGTAGAATTGGAGCACCTTCAGCCTGATGTATTA
GTCCACGCAGTACTAAGAGTTGTTGATTTCACTGTACTTACAGAGGCAGTATACAGTTATAGAG
GACAGAAGCAGAAAAAAGTTATGTTAACAGTGGAACAGGCCCAAGACAAACATTATGTGCTTGT
ATTATGGGGTCCTGGAGCAGCCTGGTACCCTCAACTTCAAAGGAAAAAAGGTTATATTTGGGAA
TTTAAATATCTTTTTGTTCAGCGCAATTACACACTAGAAAACCTAGAGTTGCATACAACACCTT
GGTCATCCTGTGAGTGCTTGTTTGATGATGATATAAGGGCAATTACATTTAAAGCAAAATTTCA
AAAAAGTACACCCGCCTTTGTGAAGATATCAGACTTAGCAGCCCACCTAGAGGATAAGTGTTCA
GGAGTGATTCTAATTAAAGCCCAGATTTCAGAGCTGGCATTTCCTACAGCAACTCAGAAGATAG
CTCTAAATGCTCACAGTTCTCTGAAGAGTATTTTCTCTTCTCTTCCCAACATCGTATATACTGG
CTGCGCAAAATGTGGATTGGAACTAGAAACAGATGAGAACAGGATCTATAAACAGTGTTTTAGC
TGCTTGCCATTTACTATGAAGAAAATACACTATAGGCCAGCCTTAATGACTGTAGTTGATGGAA
GACATGATGTTTGCATCCGTGTAGAATCAAAGCTGATAGAGAAGATTCTTCTCAACATTTCTGC
AGACTGCCTCAACAGAGTGATAGTTCCTTCCTCAGACATCACCTATGGGATGGTCGTGGCAGAC
CTGTTCCACTCCTTGCTGGCAGTCAACGCAGAACCTTGTGTATTGAAGATTCAGAGCCTTTTTG
TGTCAGATGAAAACAGCTATCCATTACAACAAGATTTCTCCCTCCTGGATTTTTATCCTGACAT
TGTAAAGCATGGAGCCGATGCCCTTCTTTGTGGCCAGAGGAAGAAATTGTAGACATTTCAAGGA
AGAAGTACTGAAATGATTTGTCTTTTGAAATAAATGAATGACAGGACTTTTGCTTTGGATTTTT
TATTAAATATATTTTACGAAGAGAATTGCAGTAGATATATAAATTAAAACTTTTTTCTAAGAAA
ATCCTGTGAGGTTTAAAAAGATTGTTTTTGTTTTTTTGGTTTCTTCCTTTCTTCTGGAGAAATG
ATCTACCAGTCAAAGCAATATGTAGCCGATCCCTGGGAATTAAAGGTTTGCCCATTTGTTCACT
GTGTTTAGTCCCTGCTGCATTCCAGGCATTGTACTAAGTATGGGGAACTACATGGAAGACAGTC
CCTCAGAAACTGCTGCAGTGCTTTTGCTTATCCCTACCTAAAAAACCGTCAATGTGAAATCATT
TCCTTGATTATAACTATACATGATAATGGATTAGTTTATATAAACCTATGTTTAGACAAGTTCA
AAACAAGCGTGTCTTTCTATAAAAAGCTTTGAAAATGAAGGAAATGAGATCATGTTTCAATTTA
TTAAAGCGGAGAAGAGCGTTCTGTGGTTAGTTCGTGTCTAGGATTTGAGTGCCTTACTGAATGT
ATTTACCAGCAAACATGTAGCAATCGGTTCTCTCATTGTGATGGTAGAAGCTCATGTAAAATGG
TAGTCATTAATGAGGAAGTATGGAGTGGTACTTATTCTGTAAGTTCAGAGTATGCCAAGTGTTA
ATATATTATCATATTGCCTGAAAATAAATTTATGATGATATGAACAAGCTTA

hide sequence

RefSeq Acc Id:

XM_038008940 ⟹ XP_037864868

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
Vero_WHO_p1.0	NW_023666048	4,377,310 - 4,464,555 (-)	NCBI

RefSeq Acc Id:

XM_038008941 ⟹ XP_037864869

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
Vero_WHO_p1.0	NW_023666048	4,377,310 - 4,441,297 (-)	NCBI

RefSeq Acc Id:

XM_038008942 ⟹ XP_037864870

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
Vero_WHO_p1.0	NW_023666048	4,377,310 - 4,464,555 (-)	NCBI

RefSeq Acc Id:

XM_038008944 ⟹ XP_037864872

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
Vero_WHO_p1.0	NW_023666048	4,377,310 - 4,464,557 (-)	NCBI

RefSeq Acc Id:

XM_038008945 ⟹ XP_037864873

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
Vero_WHO_p1.0	NW_023666048	4,377,310 - 4,464,557 (-)	NCBI

RefSeq Acc Id:

XM_038008946 ⟹ XP_037864874

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
Vero_WHO_p1.0	NW_023666048	4,377,310 - 4,464,557 (-)	NCBI

RefSeq Acc Id:

XM_038008947 ⟹ XP_037864875

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
Vero_WHO_p1.0	NW_023666048	4,377,310 - 4,464,546 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_007960866	(Get FASTA)	NCBI Sequence Viewer
	XP_007960869	(Get FASTA)	NCBI Sequence Viewer
	XP_007960870	(Get FASTA)	NCBI Sequence Viewer
	XP_007960873	(Get FASTA)	NCBI Sequence Viewer
	XP_037864868	(Get FASTA)	NCBI Sequence Viewer
	XP_037864869	(Get FASTA)	NCBI Sequence Viewer
	XP_037864870	(Get FASTA)	NCBI Sequence Viewer
	XP_037864872	(Get FASTA)	NCBI Sequence Viewer
	XP_037864873	(Get FASTA)	NCBI Sequence Viewer
	XP_037864874	(Get FASTA)	NCBI Sequence Viewer
	XP_037864875	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000006121.1

RefSeq Acc Id:	XP_007960869 ⟸ XM_007962678
- Peptide Label:	isoform X2
- UniProtKB:	A0A0D9RBY2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_007960873 ⟸ XM_007962682
- Peptide Label:	isoform X8

RefSeq Acc Id:	XP_007960866 ⟸ XM_007962675
- Peptide Label:	isoform X2
- UniProtKB:	A0A0D9RBY2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_007960870 ⟸ XM_007962679
- Peptide Label:	isoform X6

RefSeq Acc Id:

ENSCSAP00000006121 ⟸ ENSCSAT00000007963

RefSeq Acc Id:	XP_037864874 ⟸ XM_038008946
- Peptide Label:	isoform X5
- UniProtKB:	A0A0D9RBY2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_037864872 ⟸ XM_038008944
- Peptide Label:	isoform X3
- UniProtKB:	A0A0D9RBY2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_037864873 ⟸ XM_038008945
- Peptide Label:	isoform X4
- UniProtKB:	A0A0D9RBY2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_037864870 ⟸ XM_038008942
- Peptide Label:	isoform X2
- UniProtKB:	A0A0D9RBY2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_037864868 ⟸ XM_038008940
- Peptide Label:	isoform X1
- UniProtKB:	A0A0D9RBY2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_037864875 ⟸ XM_038008947
- Peptide Label:	isoform X7

RefSeq Acc Id:	XP_037864869 ⟸ XM_038008941
- Peptide Label:	isoform X1
- UniProtKB:	A0A0D9RBY2 (UniProtKB/TrEMBL)

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000009879	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000007963.1	UniProtKB/TrEMBL
InterPro	FAM35A	UniProtKB/TrEMBL
	FAM35A_C	UniProtKB/TrEMBL
	SHLD2_OB1	UniProtKB/TrEMBL
NCBI Gene	SHLD2	ENTREZGENE
PANTHER	PTHR14495	UniProtKB/TrEMBL
	SHIELDIN COMPLEX SUBUNIT 2	UniProtKB/TrEMBL
Pfam	FAM35_C	UniProtKB/TrEMBL
	SHLD2_OB1	UniProtKB/TrEMBL
UniProt	A0A0D9RBY2	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar