Mab21l3 (mab-21-like 3) - Rat Genome Database

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Gene: Mab21l3 (mab-21-like 3) Mus musculus
Analyze
Symbol: Mab21l3
Name: mab-21-like 3
RGD ID: 1318616
MGI Page MGI
Description: Orthologous to human MAB21L3 (mab-21 like 3).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: hypothetical protein LOC242125; mab-21-like 3 (C. elegans); MGC47256; protein mab-21-like 3
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393101,720,392 - 101,743,601 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3101,720,392 - 101,756,275 (-)EnsemblGRCm39 Ensembl
GRCm383101,813,076 - 101,836,283 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3101,813,076 - 101,848,959 (-)EnsemblGRCm38mm10GRCm38
MGSCv373101,616,999 - 101,640,146 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363101,942,137 - 101,965,022 (-)NCBIMGSCv36mm8
Celera3104,025,072 - 104,048,098 (-)NCBICelera
Cytogenetic Map3F2.2NCBI
cM Map344.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:14691545   PMID:16141072   PMID:16141073   PMID:21677750   PMID:22967998  


Genomics

Comparative Map Data
Mab21l3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393101,720,392 - 101,743,601 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3101,720,392 - 101,756,275 (-)EnsemblGRCm39 Ensembl
GRCm383101,813,076 - 101,836,283 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3101,813,076 - 101,848,959 (-)EnsemblGRCm38mm10GRCm38
MGSCv373101,616,999 - 101,640,146 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363101,942,137 - 101,965,022 (-)NCBIMGSCv36mm8
Celera3104,025,072 - 104,048,098 (-)NCBICelera
Cytogenetic Map3F2.2NCBI
cM Map344.3NCBI
MAB21L3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381116,111,399 - 116,138,149 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1116,111,399 - 116,138,149 (+)EnsemblGRCh38hg38GRCh38
GRCh371116,654,020 - 116,680,770 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361116,455,899 - 116,479,384 (+)NCBINCBI36Build 36hg18NCBI36
Celera1114,883,120 - 114,906,605 (+)NCBICelera
Cytogenetic Map1p13.1NCBI
HuRef1114,512,300 - 114,535,787 (+)NCBIHuRef
CHM1_11116,769,127 - 116,792,612 (+)NCBICHM1_1
T2T-CHM13v2.01116,119,359 - 116,146,123 (+)NCBIT2T-CHM13v2.0
Mab21l3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82191,937,451 - 191,960,204 (-)NCBIGRCr8
mRatBN7.22189,248,895 - 189,271,652 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2189,248,895 - 189,271,652 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2196,881,904 - 196,904,344 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02194,733,566 - 194,756,228 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02189,560,016 - 189,582,718 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02204,231,936 - 204,269,235 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2204,231,685 - 204,254,699 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02223,666,827 - 223,703,837 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42196,903,848 - 196,926,798 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12196,868,997 - 196,888,640 (-)NCBI
Celera2181,682,377 - 181,705,041 (-)NCBICelera
Cytogenetic Map2q34NCBI
Mab21l3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543519,300,476 - 19,320,332 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543519,300,663 - 19,321,257 (+)NCBIChiLan1.0ChiLan1.0
MAB21L3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21108,749,983 - 108,784,482 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11108,358,513 - 108,382,323 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0186,432,777 - 86,457,064 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11121,482,368 - 121,504,903 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1121,481,357 - 121,504,841 (-)Ensemblpanpan1.1panPan2
MAB21L3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11753,583,510 - 53,606,091 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1753,585,088 - 53,605,748 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1753,230,527 - 53,252,848 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01754,464,336 - 54,486,101 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1754,464,330 - 54,487,212 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11753,501,954 - 53,524,391 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01753,538,046 - 53,561,138 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01754,110,868 - 54,133,173 (+)NCBIUU_Cfam_GSD_1.0
Mab21l3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505813,109,216 - 13,185,341 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366271,336,726 - 1,357,668 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366271,336,731 - 1,375,501 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MAB21L3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4104,599,818 - 104,625,234 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14104,572,922 - 104,651,287 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24114,663,158 - 114,741,427 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MAB21L3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12017,581,327 - 17,639,131 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2017,580,612 - 17,602,920 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603820,274,134 - 20,344,391 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mab21l3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477211,845,855 - 11,865,929 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477211,844,823 - 11,864,342 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Mab21l3
873 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1195
Count of miRNA genes:462
Interacting mature miRNAs:546
Transcripts:ENSMUST00000061831, ENSMUST00000118411
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884436Zlq3_mzygomatic length QTL 3, 10 week (mouse)33265060142405761Mouse
4142399Aec1_mautoimmune exocrinopathy 1 (mouse)Not determined7586174102690034Mouse
26884427Cvht4_mcranial vault height 4, 10 week (mouse)316054164109707316Mouse
13207570Tcq12_mtotal cholesterol QTL 12 (mouse)316504164130163649Mouse
26884422Cvht7_mcranial vault height 7, 16 week (mouse)328954149118893649Mouse
1302056Orgwq4_morgan weight QTL 4 (mouse)Not determined330067588147304689Mouse
1301705Sles3_msystemic lupus erythmatosus suppressor 3 (mouse)Not determined337174862143353183Mouse
13208566Bmiq5_mbody mass index QTL 5 (mouse)340954435115793649Mouse
26884378Skwq6_mskull length QTL 6, 10 week (mouse)351907421102307316Mouse
26884382Bzwq1_mbi-zygomatic width QTL 1, 5 week (mouse)352207421137205761Mouse
25314313Syncl1_msynaptonemal complex length 1 (mouse)367907333128393649Mouse
11251721Ewc3_methanol withdrawal and consumption 3 (mouse)369568554103568554Mouse
1301422Sle11_msystematic lupus erythematosus susceptibility 11 (mouse)Not determined370208904104209042Mouse
11049572Lmr11c_mleishmaniasis resistance 11c (mouse)372139967106140094Mouse
1300982Lmr11_mleishmaniasis resistance 11 (mouse)Not determined372139967106140094Mouse
1300595Tmevd2_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 2 (mouse)Not determined375463302109463549Mouse
1301392Eae3_msusceptibility to experimental allergic encephalomyelitis 3 (mouse)Not determined379548730113548837Mouse
1301947Pcfm3_mperiosteal circumference and femur length 3 (mouse)Not determined381084652115084797Mouse
1301904Iba2_minduction of brown adipocytes 2 (mouse)Not determined382147043116147184Mouse
11041900Lmr11a_mleishmaniasis resistance 11a (mouse)383463991117464137Mouse
11039510Ltpr3d_mLeishmania tropica response 3d (mouse)383463991117464137Mouse
11039511Ltpr3c_mLeishmania tropica response 3c (mouse)383463991117464137Mouse
11039507Ltpr3g_mLeishmania tropica response 3g (mouse)383463991117464137Mouse
11039508Ltpr3f_mLeishmania tropica response 3f (mouse)383463991117464137Mouse
11039509Ltpr3e_mLeishmania tropica response 3e (mouse)383463991117464137Mouse
11039512Ltpr3b_mLeishmania tropica response 3b (mouse)383463991117464137Mouse
1301272Cfsw1_mcystic fibrosis survival to weaning 1 (mouse)Not determined383882912117883044Mouse
4142099Cq3_mcholesterol QTL 3 (mouse)Not determined384888918118889067Mouse
14746984Manh54_mmandible shape 54 (mouse)385289152119289152Mouse
1357583Sle18_msystematic lupus erythematosus susceptibility 18 (mouse)Not determined387208904125316236Mouse
12738440Twq3_mtestis weight QTL 3 (mouse)387228015121228015Mouse
4142178Ctrq2_mC. trachomatis resistance QTL 2 (mouse)Not determined389139967137453008Mouse
10766455Sle22_msystematic lupus erythematosus susceptibility 22 (mouse)390376936124377072Mouse
14747001Mancz4_mmandible centroid size 4 (mouse)390378017124378017Mouse
1302052Etohcta4_methanol conditioned taste aversion 4 (mouse)Not determined391000105125008748Mouse
1301349Pgia26_mproteoglycan induced arthritis 26 (mouse)Not determined392251533126251650Mouse
27226732Tibmd3_mtibia midshaft diameter 3, 10 week (mouse)396607316147805636Mouse
10043955Wt10q4_mbody weight, 10 weeks, QTL 4 (mouse)Not determined398624041132624197Mouse
11533920Mvb3_mmodifier of vibrator 3 (mouse)398635284132635383Mouse
12792984Modn1_mmodifier of Dstn neovascularization 1 (mouse)398635284132635383Mouse
1302114Tbs1_mtuberculosis severity 1 (mouse)Not determined398924105132924250Mouse
1300752Ap6q_malcohol preference 6 QTL (mouse)Not determined3100372912147045722Mouse
26884419Bzwq6_mbi-zygomatic width QTL 6, 10 week (mouse)3100607316137205761Mouse
8655600Cia5b_mcollagen induced arthritis QTL 5b (mouse)Not determined3100655184103744779Mouse
27226733Tibmd6_mtibia midshaft diameter 6, 16 week (mouse)3101307316149805637Mouse

Markers in Region
RH143014  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383101,813,718 - 101,813,865UniSTSGRCm38
MGSCv373101,617,641 - 101,617,788UniSTSGRCm37
Celera3104,025,714 - 104,025,861UniSTS
Cytogenetic Map3F2.2UniSTS
UniSTS:234784  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383101,813,794 - 101,814,006UniSTSGRCm38
MGSCv373101,617,717 - 101,617,929UniSTSGRCm37
Celera3104,025,790 - 104,026,002UniSTS
Cytogenetic Map3F2.2UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000061831   ⟹   ENSMUSP00000059212
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3101,720,392 - 101,743,539 (-)Ensembl
GRCm38.p6 Ensembl3101,813,076 - 101,836,223 (-)Ensembl
RefSeq Acc Id: ENSMUST00000118411   ⟹   ENSMUSP00000112730
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3101,720,999 - 101,756,275 (-)Ensembl
GRCm38.p6 Ensembl3101,813,683 - 101,848,959 (-)Ensembl
RefSeq Acc Id: NM_172295   ⟹   NP_758499
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393101,720,392 - 101,743,539 (-)NCBI
GRCm383101,813,076 - 101,836,223 (-)NCBI
MGSCv373101,616,999 - 101,640,146 (-)RGD
Celera3104,025,072 - 104,048,098 (-)RGD
cM Map3 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_011240120   ⟹   XP_011238422
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393101,720,995 - 101,743,601 (-)NCBI
GRCm383101,813,679 - 101,836,283 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_758499   ⟸   NM_172295
- UniProtKB: Q3TKM3 (UniProtKB/Swiss-Prot),   Q8CE43 (UniProtKB/Swiss-Prot),   Q8CI17 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011238422   ⟸   XM_011240120
- Peptide Label: isoform X1
- UniProtKB: Q3TKM3 (UniProtKB/Swiss-Prot),   Q8CE43 (UniProtKB/Swiss-Prot),   Q8CI17 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000112730   ⟸   ENSMUST00000118411
RefSeq Acc Id: ENSMUSP00000059212   ⟸   ENSMUST00000061831

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8CI17-F1-model_v2 AlphaFold Q8CI17 1-429 view protein structure

Promoters
RGD ID:6833485
Promoter ID:MM_KWN:35549
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_2Hour,   BoneMarrow_4Hour,   ES_Cell,   MEF_B6
Transcripts:NM_172295
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv363101,639,814 - 101,640,314 (-)MPROMDB
RGD ID:6881822
Promoter ID:EPDNEW_M4362
Type:initiation region
Name:Mab21l3_1
Description:Mus musculus mab-21-like 3 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm383101,836,171 - 101,836,231EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2446273 AgrOrtholog
Ensembl Genes ENSMUSG00000044313 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000061831 ENTREZGENE
  ENSMUST00000061831.11 UniProtKB/Swiss-Prot
  ENSMUST00000118411 ENTREZGENE
  ENSMUST00000118411.2 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.1410.40 UniProtKB/Swiss-Prot
  3.30.460.90 UniProtKB/Swiss-Prot
InterPro Mab-21-like_nuc_Trfase UniProtKB/Swiss-Prot
  Mab-21_dom UniProtKB/Swiss-Prot
  Mab-21_HhH/H2TH-like UniProtKB/Swiss-Prot
KEGG Report mmu:242125 UniProtKB/Swiss-Prot
MGD MGI:2446273 ENTREZGENE
NCBI Gene 242125 ENTREZGENE
PANTHER CELL FATE DETERMINING PROTEIN MAB21-RELATED UniProtKB/Swiss-Prot
  PTHR10656:SF30 UniProtKB/Swiss-Prot
Pfam Mab-21 UniProtKB/Swiss-Prot
  Mab-21_C UniProtKB/Swiss-Prot
PhenoGen Mab21l3 PhenoGen
SMART Mab-21 UniProtKB/Swiss-Prot
UniProt MB213_MOUSE UniProtKB/Swiss-Prot
  Q3TKM3 ENTREZGENE
  Q8CE43 ENTREZGENE
  Q8CI17 ENTREZGENE
UniProt Secondary Q3TKM3 UniProtKB/Swiss-Prot
  Q8CE43 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-03-12 Mab21l3  mab-21-like 3    mab-21-like 3 (C. elegans)  Symbol and/or name change 5135510 APPROVED
2011-07-27 Mab21l3  mab-21-like 3 (C. elegans)  BC037703  cDNA sequence BC037703  Symbol and/or name change 5135510 APPROVED