Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | ISO | Sat2 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of SAT2 mRNA] | CTD | PMID:31150632 | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | SAT2 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of SAT2 mRNA | CTD | PMID:22079256 | 1-naphthyl isothiocyanate | decreases expression | ISO | Sat2 (Rattus norvegicus) | 6480464 | 1-Naphthylisothiocyanate results in decreased expression of SAT2 mRNA | CTD | PMID:30723492 | 17alpha-ethynylestradiol | decreases expression | ISO | Sat2 (Rattus norvegicus) | 6480464 | Ethinyl Estradiol results in decreased expression of SAT2 mRNA | CTD | PMID:17557909 | 17beta-estradiol | decreases expression | ISO | SAT2 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of SAT2 mRNA | CTD | PMID:23019147 and PMID:31614463 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Sat2 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SAT2 mRNA | CTD | PMID:21215274 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Sat2 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of SAT2 mRNA | CTD | PMID:32109520 and PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | SAT2 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin affects the expression of SAT2 mRNA | CTD | PMID:22574217 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of SAT2 mRNA | CTD | PMID:21570461 | 2,4-dinitrotoluene | affects expression | ISO | Sat2 (Rattus norvegicus) | 6480464 | 2 and 4-dinitrotoluene affects the expression of SAT2 mRNA | CTD | PMID:21346803 | 2,6-dinitrotoluene | affects expression | ISO | Sat2 (Rattus norvegicus) | 6480464 | 2 and 6-dinitrotoluene affects the expression of SAT2 mRNA | CTD | PMID:21346803 | 2-hydroxypropanoic acid | decreases expression | ISO | SAT2 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of SAT2 mRNA | CTD | PMID:30851411 | 3-chloropropane-1,2-diol | decreases expression | ISO | Sat2 (Rattus norvegicus) | 6480464 | alpha-Chlorohydrin results in decreased expression of SAT2 protein | CTD | PMID:34915118 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | SAT2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of SAT2 mRNA | CTD | PMID:28628672 | acetamide | decreases expression | ISO | Sat2 (Rattus norvegicus) | 6480464 | acetamide results in decreased expression of SAT2 mRNA | CTD | PMID:31881176 | antirheumatic drug | increases expression | ISO | SAT2 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of SAT2 mRNA | CTD | PMID:24449571 | aristolochic acid A | increases expression | ISO | SAT2 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of SAT2 mRNA | CTD | PMID:33212167 | arsenous acid | multiple interactions | ISO | SAT2 (Homo sapiens) | 6480464 | Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to SAT2 protein] | CTD | PMID:26598702 | benzo[a]pyrene | increases expression | ISO | SAT2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of SAT2 mRNA | CTD | PMID:21632981 | bisphenol A | affects expression | ISO | Sat2 (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of SAT2 mRNA | CTD | PMID:25181051 | bisphenol A | decreases methylation | ISO | SAT2 (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of SAT2 gene | CTD | PMID:31601247 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of SAT2 mRNA | CTD | PMID:33221593 | bisphenol A | affects expression | ISO | SAT2 (Homo sapiens) | 6480464 | bisphenol A affects the expression of SAT2 mRNA | CTD | PMID:30903817 | bisphenol A | increases expression | ISO | SAT2 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of SAT2 mRNA | CTD | PMID:29275510 | bisphenol A | increases methylation | ISO | Sat2 (Rattus norvegicus) | 6480464 | bisphenol A results in increased methylation of SAT2 gene | CTD | PMID:28505145 | bisphenol F | multiple interactions | ISO | SAT2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of SAT2 mRNA | CTD | PMID:28628672 | buspirone | increases expression | ISO | Sat2 (Rattus norvegicus) | 6480464 | Buspirone results in increased expression of SAT2 mRNA | CTD | PMID:24136188 | busulfan | increases expression | EXP | | 6480464 | Busulfan results in increased expression of SAT2 mRNA and Busulfan results in increased expression of SAT2 protein | CTD | PMID:28578006 | carbamazepine | affects expression | ISO | SAT2 (Homo sapiens) | 6480464 | Carbamazepine affects the expression of SAT2 mRNA | CTD | PMID:24752500 | cerium trichloride | increases expression | EXP | | 6480464 | cerous chloride results in increased expression of SAT2 mRNA | CTD | PMID:23573234 | CGP 52608 | multiple interactions | ISO | SAT2 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to SAT2 gene] | CTD | PMID:28238834 | copper atom | increases expression | ISO | Sat2 (Rattus norvegicus) | 6480464 | Copper results in increased expression of SAT2 mRNA | CTD | PMID:30556269 | copper(0) | increases expression | ISO | Sat2 (Rattus norvegicus) | 6480464 | Copper results in increased expression of SAT2 mRNA | CTD | PMID:30556269 | crocidolite asbestos | increases expression | ISO | SAT2 (Homo sapiens) | 6480464 | Asbestos and Crocidolite results in increased expression of SAT2 mRNA | CTD | PMID:29523930 | cyclosporin A | increases expression | ISO | SAT2 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of SAT2 mRNA | CTD | PMID:25562108 | dexamethasone | multiple interactions | ISO | SAT2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of SAT2 mRNA | CTD | PMID:28628672 | diarsenic trioxide | multiple interactions | ISO | SAT2 (Homo sapiens) | 6480464 | Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to SAT2 protein] | CTD | PMID:26598702 | dibutyl phthalate | decreases expression | ISO | Sat2 (Rattus norvegicus) | 6480464 | Dibutyl Phthalate results in decreased expression of SAT2 mRNA | CTD | PMID:21266533 | diclofenac | affects expression | ISO | SAT2 (Homo sapiens) | 6480464 | Diclofenac affects the expression of SAT2 mRNA | CTD | PMID:24752500 | diuron | decreases expression | ISO | SAT2 (Homo sapiens) | 6480464 | Diuron results in decreased expression of SAT2 mRNA | CTD | PMID:35967413 | dorsomorphin | multiple interactions | ISO | SAT2 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | doxorubicin | increases expression | ISO | SAT2 (Homo sapiens) | 6480464 | Doxorubicin results in increased expression of SAT2 mRNA | CTD | PMID:29803840 | endosulfan | increases expression | ISO | Sat2 (Rattus norvegicus) | 6480464 | Endosulfan results in increased expression of SAT2 mRNA | CTD | PMID:29391264 | ethyl methanesulfonate | increases expression | ISO | SAT2 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of SAT2 mRNA | CTD | PMID:23649840 | flutamide | decreases expression | ISO | Sat2 (Rattus norvegicus) | 6480464 | Flutamide results in decreased expression of SAT2 mRNA | CTD | PMID:24136188 | formaldehyde | increases expression | ISO | SAT2 (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of SAT2 mRNA | CTD | PMID:23649840 | glafenine | decreases expression | ISO | Sat2 (Rattus norvegicus) | 6480464 | Glafenine results in decreased expression of SAT2 mRNA | CTD | PMID:24136188 | hydrogen peroxide | affects expression | ISO | SAT2 (Homo sapiens) | 6480464 | Hydrogen Peroxide affects the expression of SAT2 mRNA | CTD | PMID:20044591 | indometacin | multiple interactions | ISO | SAT2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of SAT2 mRNA | CTD | PMID:28628672 | indometacin | decreases expression | ISO | Sat2 (Rattus norvegicus) | 6480464 | Indomethacin results in decreased expression of SAT2 mRNA | CTD | PMID:36868495 | lead(0) | affects splicing | ISO | SAT2 (Homo sapiens) | 6480464 | Lead affects the splicing of SAT2 mRNA | CTD | PMID:28903495 | leflunomide | increases expression | ISO | Sat2 (Rattus norvegicus) | 6480464 | leflunomide results in increased expression of SAT2 mRNA | CTD | PMID:24136188 | methyl methanesulfonate | increases expression | ISO | SAT2 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of SAT2 mRNA | CTD | PMID:23649840 | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of SAT2 mRNA | CTD | PMID:17562736 | paraquat | decreases expression | ISO | Sat2 (Rattus norvegicus) | 6480464 | Paraquat results in decreased expression of SAT2 mRNA | CTD | PMID:32680482 | phenobarbital | affects expression | ISO | SAT2 (Homo sapiens) | 6480464 | Phenobarbital affects the expression of SAT2 mRNA | CTD | PMID:19159669 | pirinixic acid | multiple interactions | ISO | SAT2 (Homo sapiens) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of SAT2 mRNA | CTD | PMID:19710929 | pirinixic acid | decreases expression | EXP | | 6480464 | pirinixic acid results in decreased expression of SAT2 mRNA | CTD | PMID:20813756 and PMID:23811191 | potassium chromate | increases expression | ISO | SAT2 (Homo sapiens) | 6480464 | potassium chromate(VI) results in increased expression of SAT2 mRNA | CTD | PMID:22079256 | potassium chromate | multiple interactions | ISO | SAT2 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of SAT2 mRNA | CTD | PMID:22079256 | pravastatin | decreases expression | EXP | | 6480464 | Pravastatin results in decreased expression of SAT2 mRNA | CTD | PMID:27225895 | pravastatin | decreases expression | ISO | Sat2 (Rattus norvegicus) | 6480464 | Pravastatin results in decreased expression of SAT2 mRNA | CTD | PMID:27225895 | rac-lactic acid | decreases expression | ISO | SAT2 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of SAT2 mRNA | CTD | PMID:30851411 | resveratrol | multiple interactions | ISO | SAT2 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of SAT2 mRNA | CTD | PMID:23557933 | rotenone | increases expression | ISO | Sat2 (Rattus norvegicus) | 6480464 | Rotenone results in increased expression of SAT2 mRNA | CTD | PMID:28374803 | SB 431542 | multiple interactions | ISO | SAT2 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | sodium arsenite | increases expression | ISO | SAT2 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of SAT2 mRNA | CTD | PMID:22714537 | sulindac | increases activity | EXP | | 6480464 | Sulindac results in increased activity of SAT2 protein | CTD | PMID:17474863 | sulindac | increases expression | EXP | | 6480464 | Sulindac results in increased expression of SAT2 mRNA | CTD | PMID:17474863 | tetrachloromethane | affects expression | EXP | | 6480464 | Carbon Tetrachloride affects the expression of SAT2 mRNA | CTD | PMID:17484886 | tetrachloromethane | multiple interactions | ISO | Sat2 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of SAT2 mRNA] | CTD | PMID:31150632 | tetrachloromethane | decreases expression | ISO | Sat2 (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in decreased expression of SAT2 mRNA | CTD | PMID:31150632 | thioacetamide | decreases expression | ISO | Sat2 (Rattus norvegicus) | 6480464 | Thioacetamide results in decreased expression of SAT2 mRNA | CTD | PMID:23411599 and PMID:34492290 | trichloroethene | increases methylation | ISO | Sat2 (Rattus norvegicus) | 6480464 | Trichloroethylene results in increased methylation of SAT2 gene | CTD | PMID:27618143 | trichloroethene | increases expression | ISO | Sat2 (Rattus norvegicus) | 6480464 | Trichloroethylene results in increased expression of SAT2 mRNA | CTD | PMID:33387578 | trichostatin A | decreases expression | ISO | SAT2 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of SAT2 mRNA | CTD | PMID:26272509 | trichostatin A | multiple interactions | ISO | SAT2 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SAT2 mRNA | CTD | PMID:27188386 | trimellitic anhydride | decreases expression | EXP | | 6480464 | trimellitic anhydride results in decreased expression of SAT2 mRNA | CTD | PMID:19042947 | valproic acid | affects expression | ISO | SAT2 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of SAT2 mRNA | CTD | PMID:25979313 | valproic acid | multiple interactions | ISO | SAT2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SAT2 mRNA | CTD | PMID:27188386 | valproic acid | decreases expression | ISO | SAT2 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of SAT2 mRNA | CTD | PMID:23179753 more ... | zaragozic acid A | decreases expression | EXP | | 6480464 | squalestatin 1 results in decreased expression of SAT2 mRNA | CTD | PMID:27225895 | zaragozic acid A | increases expression | ISO | Sat2 (Rattus norvegicus) | 6480464 | squalestatin 1 results in increased expression of SAT2 mRNA | CTD | PMID:27225895 | |