Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | decreases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of HSD17B14 mRNA | CTD | PMID:22206623 | 1-naphthyl isothiocyanate | decreases expression | ISO | Hsd17b14 (Rattus norvegicus) | 6480464 | 1-Naphthylisothiocyanate results in decreased expression of HSD17B14 mRNA | CTD | PMID:30723492 | 17beta-estradiol | decreases expression | ISO | HSD17B14 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of HSD17B14 mRNA | CTD | PMID:21185374 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of HSD17B14 mRNA | CTD | PMID:21570461 | 4-hydroxyphenyl retinamide | decreases expression | EXP | | 6480464 | Fenretinide results in decreased expression of HSD17B14 mRNA | CTD | PMID:28973697 | 5-aza-2'-deoxycytidine | affects expression | ISO | HSD17B14 (Homo sapiens) | 6480464 | Decitabine affects the expression of HSD17B14 mRNA | CTD | PMID:23300844 | 8-Br-cAMP | decreases expression | ISO | HSD17B14 (Homo sapiens) | 6480464 | 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of HSD17B14 mRNA | CTD | PMID:22079614 | aflatoxin B1 | decreases expression | ISO | HSD17B14 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased expression of HSD17B14 mRNA | CTD | PMID:27153756 | Aflatoxin B2 alpha | increases methylation | ISO | HSD17B14 (Homo sapiens) | 6480464 | aflatoxin B2 results in increased methylation of HSD17B14 intron | CTD | PMID:30157460 | alpha-Zearalanol | multiple interactions | ISO | Hsd17b14 (Rattus norvegicus) | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of HSD17B14 mRNA | CTD | PMID:35163327 | antirheumatic drug | decreases expression | ISO | HSD17B14 (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of HSD17B14 mRNA | CTD | PMID:24449571 | aristolochic acid A | increases expression | ISO | HSD17B14 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of HSD17B14 mRNA | CTD | PMID:33212167 | avobenzone | increases expression | ISO | HSD17B14 (Homo sapiens) | 6480464 | avobenzone results in increased expression of HSD17B14 mRNA | CTD | PMID:31016361 | benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene results in decreased expression of HSD17B14 mRNA | CTD | PMID:23735875 | benzo[a]pyrene | affects methylation | ISO | HSD17B14 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of HSD17B14 5' UTR and Benzo(a)pyrene affects the methylation of HSD17B14 intron | CTD | PMID:27901495 and PMID:30157460 | benzo[a]pyrene | increases methylation | EXP | | 6480464 | Benzo(a)pyrene results in increased methylation of HSD17B14 exon and Benzo(a)pyrene results in increased methylation of HSD17B14 intron | CTD | PMID:27901495 | benzo[e]pyrene | increases methylation | ISO | HSD17B14 (Homo sapiens) | 6480464 | benzo(e)pyrene results in increased methylation of HSD17B14 intron | CTD | PMID:30157460 | bisphenol A | decreases expression | ISO | HSD17B14 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of HSD17B14 mRNA | CTD | PMID:19371625 | bisphenol A | increases expression | ISO | HSD17B14 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of HSD17B14 mRNA and bisphenol A results in increased expression of HSD17B14 protein | CTD | PMID:27685785 and PMID:29275510 | chlorpyrifos | increases expression | EXP | | 6480464 | Chlorpyrifos results in increased expression of HSD17B14 mRNA | CTD | PMID:37019170 | chrysene | increases expression | EXP | | 6480464 | chrysene results in increased expression of HSD17B14 mRNA | CTD | PMID:26377693 | cisplatin | affects expression | ISO | HSD17B14 (Homo sapiens) | 6480464 | Cisplatin affects the expression of HSD17B14 mRNA | CTD | PMID:23300844 | cisplatin | multiple interactions | ISO | HSD17B14 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of HSD17B14 mRNA | CTD | PMID:27392435 | copper atom | increases expression | ISO | Hsd17b14 (Rattus norvegicus) | 6480464 | Copper deficiency results in increased expression of HSD17B14 mRNA | CTD | PMID:26033743 | copper(0) | increases expression | ISO | Hsd17b14 (Rattus norvegicus) | 6480464 | Copper deficiency results in increased expression of HSD17B14 mRNA | CTD | PMID:26033743 | epoxiconazole | increases expression | EXP | | 6480464 | epoxiconazole results in increased expression of HSD17B14 mRNA | CTD | PMID:35436446 | fenvalerate | increases expression | ISO | Hsd17b14 (Rattus norvegicus) | 6480464 | fenvalerate results in increased expression of HSD17B14 mRNA | CTD | PMID:30307764 | fipronil | multiple interactions | ISO | HSD17B14 (Homo sapiens) | 6480464 | [fipronil co-treated with DEET] results in increased expression of HSD17B14 mRNA | CTD | PMID:27091632 | fipronil | increases expression | ISO | HSD17B14 (Homo sapiens) | 6480464 | fipronil results in increased expression of HSD17B14 mRNA | CTD | PMID:27091632 | fluoxetine | increases expression | ISO | HSD17B14 (Homo sapiens) | 6480464 | Fluoxetine results in increased expression of HSD17B14 mRNA | CTD | PMID:37386098 | genistein | decreases expression | ISO | HSD17B14 (Homo sapiens) | 6480464 | Genistein results in decreased expression of HSD17B14 mRNA | CTD | PMID:19371625 | hydrogen peroxide | multiple interactions | ISO | HSD17B14 (Homo sapiens) | 6480464 | [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of HSD17B14 protein | CTD | PMID:18951874 | methapyrilene | increases methylation | ISO | HSD17B14 (Homo sapiens) | 6480464 | Methapyrilene results in increased methylation of HSD17B14 intron | CTD | PMID:30157460 | N,N-diethyl-m-toluamide | multiple interactions | ISO | HSD17B14 (Homo sapiens) | 6480464 | [fipronil co-treated with DEET] results in increased expression of HSD17B14 mRNA | CTD | PMID:27091632 | N-methyl-4-phenylpyridinium | increases expression | ISO | HSD17B14 (Homo sapiens) | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of HSD17B14 mRNA | CTD | PMID:24810058 | NAD zwitterion | multiple interactions | ISO | HSD17B14 (Homo sapiens) | 6480464 | NAD binds to and results in increased activity of HSD17B14 protein | CTD | PMID:25526675 | NAD(+) | multiple interactions | ISO | HSD17B14 (Homo sapiens) | 6480464 | NAD binds to and results in increased activity of HSD17B14 protein | CTD | PMID:25526675 | niclosamide | increases expression | ISO | HSD17B14 (Homo sapiens) | 6480464 | Niclosamide results in increased expression of HSD17B14 mRNA | CTD | PMID:36318118 | perfluorooctane-1-sulfonic acid | increases expression | EXP | | 6480464 | perfluorooctane sulfonic acid results in increased expression of HSD17B14 protein | CTD | PMID:26178269 | perfluorooctanoic acid | multiple interactions | ISO | Hsd17b14 (Rattus norvegicus) | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of HSD17B14 mRNA | CTD | PMID:35163327 | rotenone | increases expression | ISO | HSD17B14 (Homo sapiens) | 6480464 | Rotenone results in increased expression of HSD17B14 mRNA | CTD | PMID:29955902 | silicon dioxide | increases expression | ISO | HSD17B14 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of HSD17B14 mRNA | CTD | PMID:25895662 | silver atom | increases expression | EXP | | 6480464 | Silver results in increased expression of HSD17B14 mRNA | CTD | PMID:27131904 | silver(0) | increases expression | EXP | | 6480464 | Silver results in increased expression of HSD17B14 mRNA | CTD | PMID:27131904 | sotorasib | multiple interactions | ISO | HSD17B14 (Homo sapiens) | 6480464 | [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of HSD17B14 mRNA | CTD | PMID:36139627 | sunitinib | increases expression | ISO | HSD17B14 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of HSD17B14 mRNA | CTD | PMID:31533062 | temozolomide | decreases expression | ISO | HSD17B14 (Homo sapiens) | 6480464 | Temozolomide results in decreased expression of HSD17B14 mRNA | CTD | PMID:31758290 | theophylline | multiple interactions | ISO | HSD17B14 (Homo sapiens) | 6480464 | [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of HSD17B14 protein | CTD | PMID:18951874 | thioacetamide | decreases expression | ISO | Hsd17b14 (Rattus norvegicus) | 6480464 | Thioacetamide results in decreased expression of HSD17B14 mRNA | CTD | PMID:34492290 | trametinib | multiple interactions | ISO | HSD17B14 (Homo sapiens) | 6480464 | [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of HSD17B14 mRNA | CTD | PMID:36139627 | trichloroethene | increases expression | ISO | Hsd17b14 (Rattus norvegicus) | 6480464 | Trichloroethylene results in increased expression of HSD17B14 mRNA | CTD | PMID:33387578 | trichostatin A | decreases expression | ISO | HSD17B14 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of HSD17B14 mRNA | CTD | PMID:24935251 | valproic acid | decreases expression | ISO | HSD17B14 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of HSD17B14 mRNA | CTD | PMID:24935251 and PMID:28001369 | vancomycin | increases expression | EXP | | 6480464 | Vancomycin results in increased expression of HSD17B14 mRNA | CTD | PMID:18930951 | zearalenone | decreases expression | ISO | HSD17B14 (Homo sapiens) | 6480464 | Zearalenone results in decreased expression of HSD17B14 mRNA | CTD | PMID:19371625 | |