Hsd17b14 (hydroxysteroid 17-beta dehydrogenase 14) - Rat Genome Database

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Gene: Hsd17b14 (hydroxysteroid 17-beta dehydrogenase 14) Ictidomys tridecemlineatus
Analyze
Symbol: Hsd17b14
Name: hydroxysteroid 17-beta dehydrogenase 14
RGD ID: 125004553
Description: ENCODES a protein that exhibits identical protein binding (ortholog); testosterone 17-beta-dehydrogenase (NADP+) activity (ortholog); INVOLVED IN steroid catabolic process (inferred); ASSOCIATED WITH High Myopia (ortholog); FOUND IN cytosol (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 17-beta-hydroxysteroid dehydrogenase 14
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934921,260,376 - 21,271,981 (-)NCBIHiC_Itri_2


Disease Annotations     Click to see Annotation Detail View
High Myopia  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IEA)

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Hsd17b14
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934921,260,376 - 21,271,981 (-)NCBIHiC_Itri_2
HSD17B14
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381948,813,018 - 48,836,491 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1948,813,018 - 48,836,510 (-)EnsemblGRCh38hg38GRCh38
GRCh371949,316,275 - 49,339,748 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361954,008,086 - 54,031,746 (-)NCBINCBI36Build 36hg18NCBI36
Build 341954,008,085 - 54,031,746NCBI
Celera1946,184,096 - 46,207,298 (-)NCBICelera
Cytogenetic Map19q13.33NCBI
HuRef1945,695,815 - 45,716,367 (-)NCBIHuRef
CHM1_11949,318,079 - 49,341,820 (-)NCBICHM1_1
T2T-CHM13v2.01951,808,041 - 51,831,370 (-)NCBIT2T-CHM13v2.0
Hsd17b14
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39745,204,345 - 45,216,745 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl745,204,317 - 45,217,176 (+)EnsemblGRCm39 Ensembl
GRCm38745,554,920 - 45,567,321 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl745,554,893 - 45,567,752 (+)EnsemblGRCm38mm10GRCm38
MGSCv37752,810,298 - 52,822,691 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36745,430,239 - 45,435,363 (+)NCBIMGSCv36mm8
Celera741,011,410 - 41,020,538 (+)NCBICelera
Cytogenetic Map7B3NCBI
cM Map729.35NCBI
Hsd17b14
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81105,165,695 - 105,176,045 (+)NCBIGRCr8
mRatBN7.2196,029,224 - 96,039,577 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl196,029,284 - 96,039,883 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1101,414,727 - 101,424,520 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01109,887,411 - 109,897,212 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01103,177,803 - 103,187,600 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01101,541,266 - 101,551,059 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1101,541,266 - 101,551,059 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01102,620,046 - 102,629,839 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4196,024,911 - 96,034,704 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera190,284,805 - 90,294,592 (+)NCBICelera
Cytogenetic Map1q22NCBI
Hsd17b14
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555591,775,971 - 1,784,265 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555591,775,889 - 1,784,598 (+)NCBIChiLan1.0ChiLan1.0
HSD17B14
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22054,916,483 - 54,941,333 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11956,840,193 - 56,867,306 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01945,812,558 - 45,837,292 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11954,918,603 - 54,942,676 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1954,918,606 - 54,942,676 (+)Ensemblpanpan1.1panPan2
HSD17B14
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11107,517,954 - 107,536,877 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1107,518,058 - 107,536,873 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1107,040,507 - 107,059,329 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01108,042,565 - 108,061,515 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1108,042,665 - 108,178,953 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11107,709,599 - 107,728,429 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01107,356,488 - 107,375,313 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01108,192,102 - 108,210,923 (+)NCBIUU_Cfam_GSD_1.0
HSD17B14
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1654,125,229 - 54,144,143 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2649,872,601 - 49,891,519 (-)NCBISscrofa10.2Sscrofa10.2susScr3
HSD17B14
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1642,052,330 - 42,075,843 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607321,930,636 - 21,955,318 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_040279191   ⟹   XP_040135125
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934921,260,376 - 21,271,981 (-)NCBI
RefSeq Acc Id: XM_040279192   ⟹   XP_040135126
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934921,260,376 - 21,271,981 (-)NCBI
RefSeq Acc Id: XM_040279193   ⟹   XP_040135127
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934921,260,376 - 21,271,981 (-)NCBI
Protein Sequences
Protein RefSeqs XP_040135125 (Get FASTA)   NCBI Sequence Viewer  
  XP_040135126 (Get FASTA)   NCBI Sequence Viewer  
  XP_040135127 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000003917.2
Reference Protein Sequences
RefSeq Acc Id: XP_040135127   ⟸   XM_040279193
- Peptide Label: isoform X3
RefSeq Acc Id: XP_040135126   ⟸   XM_040279192
- Peptide Label: isoform X2
RefSeq Acc Id: XP_040135125   ⟸   XM_040279191
- Peptide Label: isoform X1
- UniProtKB: I3M436 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000004348 UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000004364.3 UniProtKB/TrEMBL
Gene3D-CATH NAD(P)-binding Rossmann-like Domain UniProtKB/TrEMBL
InterPro NAD(P)-bd_dom_sf UniProtKB/TrEMBL
  Sc_DH/Rdtase_CS UniProtKB/TrEMBL
  SDR_fam UniProtKB/TrEMBL
NCBI Gene Hsd17b14 ENTREZGENE
PANTHER 17-BETA-HYDROXYSTEROID DEHYDROGENASE 14 UniProtKB/TrEMBL
  SHORT-CHAIN DEHYDROGENASE/REDUCTASE UniProtKB/TrEMBL
Pfam adh_short_C2 UniProtKB/TrEMBL
PRINTS GDHRDH UniProtKB/TrEMBL
  SDRFAMILY UniProtKB/TrEMBL
PROSITE ADH_SHORT UniProtKB/TrEMBL
Superfamily-SCOP SSF51735 UniProtKB/TrEMBL
UniProt I3M436 ENTREZGENE, UniProtKB/TrEMBL