Fdps (farnesyl diphosphate synthase)

Gene: Fdps (farnesyl diphosphate synthase) Ictidomys tridecemlineatus

Analyze

Symbol:

Fdps

Name:

farnesyl diphosphate synthase

RGD ID:

12580903

Description:

ENCODES a protein that exhibits geranyltranstransferase activity (ortholog); INVOLVED IN cellular response to fatty acid (ortholog); farnesyl diphosphate biosynthetic process (ortholog); male gonad development (ortholog); PARTICIPATES IN alendronate pharmacodynamics pathway; cholesterol biosynthetic pathway; cholesterol ester storage disease pathway; ASSOCIATED WITH Charcot-Marie-Tooth disease type 2 (ortholog); gastrointestinal stromal tumor (ortholog); immunodeficiency 42 (ortholog); FOUND IN cytosol (ortholog); mitochondrial matrix (ortholog); nucleoplasm (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

farnesyl diphosphate synthase, transcript variant X1; farnesyl diphosphate synthase, transcript variant X2; farnesyl diphosphate synthase, transcript variant X3; farnesyl pyrophosphate synthase

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	25,768,903 - 25,778,024 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936580	4,799,354 - 4,808,406 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Charcot-Marie-Tooth disease type 2 (ISO)

gastrointestinal stromal tumor (ISO)

immunodeficiency 42 (ISO)

MHC class II deficiency (ISO)

parathyroid carcinoma (ISO)

Porokeratosis 9, Multiple Types (ISO)

Postmenopausal Osteoporosis (ISO)

severe congenital neutropenia 3 (ISO)

severe congenital neutropenia 5 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to fatty acid (ISO)

farnesyl diphosphate biosynthetic process (IEA,ISO)

isoprenoid biosynthetic process (IEA)

male gonad development (ISO)

positive regulation of cell growth involved in cardiac muscle cell development (ISO)

positive regulation of cholesterol biosynthetic process (ISO)

response to cholesterol (ISO)

response to peptide hormone (ISO)

response to testosterone (ISO)

response to xenobiotic stimulus (ISO)

spermatogenesis (ISO)

Cellular Component

cytoplasm (IEA)

cytosol (ISO)

mitochondrial matrix (ISO)

nucleoplasm (ISO)

peroxisome (ISO)

Molecular Function

dimethylallyltranstransferase activity (IEA)

geranyltranstransferase activity (IEA,ISO)

protein binding (ISO)

transferase activity (IEA)

transferase activity, transferring alkyl or aryl (other than methyl) groups (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

alendronate pharmacodynamics pathway (ISO)

cholesterol biosynthetic pathway (ISO)

cholesterol ester storage disease pathway (ISO)

congenital hemidysplasia with ichthyosiform erythroderma and limb defects pathway (ISO)

desmosterolosis pathway (ISO)

hypercholesterolemia pathway (ISO)

ibandronate pharmacodynamics pathway (ISO)

mevalonic aciduria pathway (ISO)

nitrogenous bisphosphonate pharmacodynamics pathway (ISO)

pamidronate pharmacodynamics pathway (ISO)

risedronate pharmacodynamics pathway (ISO)

Smith-Lemli-Opitz Syndrome pathway (ISO)

statin pharmacodynamics pathway (ISO)

Wolman disease pathway (ISO)

X-linked dominant chondrodysplasia punctata 2 pathway (ISO)

zoledronate pharmacodynamics pathway (ISO)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

Fdps
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	25,768,903 - 25,778,024 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936580	4,799,354 - 4,808,406 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

FDPS
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	155,308,866 - 155,320,665 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	155,308,748 - 155,320,666 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	155,278,657 - 155,290,456 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	153,545,374 - 153,557,080 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	152,092,649 - 152,103,529	NCBI
Celera	1	128,351,680 - 128,363,599 (+)	NCBI		Celera
Cytogenetic Map	1	q22	NCBI
HuRef	1	126,640,838 - 126,652,759 (+)	NCBI		HuRef
CHM1_1	1	156,673,976 - 156,685,898 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	154,447,406 - 154,459,205 (+)	NCBI		T2T-CHM13v2.0

Fdps
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	89,000,895 - 89,009,274 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	89,000,895 - 89,009,266 (-)	Ensembl		GRCm39 Ensembl
GRCm38	3	89,093,588 - 89,101,967 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	89,093,588 - 89,101,959 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	3	88,897,510 - 88,905,867 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	3	89,179,515 - 89,187,872 (-)	NCBI		MGSCv36	mm8
Celera	3	89,132,279 - 89,140,636 (-)	NCBI		Celera
Cytogenetic Map	3	F1	NCBI
cM Map	3	39.01	NCBI

Fdps
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	176,795,192 - 176,804,816 (-)	NCBI		GRCr8
mRatBN7.2	2	174,497,402 - 174,507,031 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	174,486,665 - 174,507,776 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	181,643,561 - 181,653,177 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	179,665,921 - 179,675,537 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	174,265,880 - 174,275,498 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	188,403,595 - 188,413,219 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	188,392,858 - 188,413,219 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	207,816,332 - 207,826,348 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	181,138,474 - 181,177,903 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	181,119,007 - 181,128,009 (-)	NCBI
Celera	2	168,441,483 - 168,451,110 (-)	NCBI		Celera
Cytogenetic Map	2	q34	NCBI

Fdps
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955545	1,757,418 - 1,765,028 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955545	1,757,090 - 1,765,028 (+)	NCBI	ChiLan1.0	ChiLan1.0

FDPS
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	94,523,831 - 94,535,834 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	94,255,158 - 94,267,161 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	130,653,316 - 130,665,196 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	134,258,881 - 134,270,237 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	134,258,968 - 134,270,237 (+)	Ensembl	panpan1.1		panPan2

FDPS
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	42,241,086 - 42,250,373 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	7	42,241,107 - 42,250,225 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	41,731,911 - 41,741,200 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	42,110,187 - 42,119,478 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	7	42,110,191 - 42,119,346 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	7	41,890,063 - 41,899,349 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	41,943,839 - 41,953,128 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	42,227,832 - 42,237,121 (-)	NCBI		UU_Cfam_GSD_1.0

FDPS
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	94,500,141 - 94,518,408 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	94,500,140 - 94,514,820 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	103,291,797 - 103,304,940 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

FDPS
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	8,514,311 - 8,526,363 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666038	7,851,669 - 7,864,161 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Fdps
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624885	943,571 - 949,528 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624885	942,998 - 949,529 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005331351	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005331352	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005331353	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000117	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

XM_005331351 ⟹ XP_005331408

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405058	25,769,867 - 25,778,024 (+)	NCBI
SpeTri2.0	NW_004936580	4,800,249 - 4,808,406 (+)	NCBI

Sequence:

show sequence

GGAGTGCACAGTACCCCTCCCTATGCCACCTCCACCATGCCCCTGTCCCGCTGGCTGAGATCTG
TGGGGGTCTTCCTGCTGCCAGCCCCCTGCTGGGCGCCTAGGGAGAGGTTTCTGGGTTACCTACG
GCGGCCCTCCCTGGTGCACGGGTGCCCAGTCCTGGGGGCCTGGCACAGTGCCCGCTGCTGGTGC
CAAGTGTGGACAGAGGAGCCTCGAGCACTTTGCTCCTCTCTCAGAATGAACGGAGACCAGAAAT
CAGATGGTTATGCTCAGGAAAAGCAGGATTTCATCCAGCACTTCTCCCAGATAGTCAAGGTGCT
GACTGAAGATGAGATGGGGCACCCAGAGACAGGAGATGCTATTGCTCGACTCAAGGAGGTCCTG
GAATATAATGCCATTGGAGGCAAGTACAACCGGGGTTTGACGGTGGTGGTAGCATTCCGGGAGC
TGGCGGATCCAAGAAAACAGGATGCTGATAGTCTCCAGAGGGCCCTGACAGTGGGCTGGTGTGT
GGAACTGCTTCAAGCTTTCTTCCTGGTGTCAGATGACATCATGGATGCATCCCTTACCCGCCGG
GGACAGCTCTGCTGGTATCAGAAGCCAGGCATAGGTTTGGATGCCATCAATGACTGTCTGCTTC
TGGAAGCATGTATCTACCGACTGCTGAAGTTCTACTGCCGGGATCAGCCCTACTATTTGAACTT
GATTGAGCTATTCCTGCAGAGTTCCTATCAGACGGAGATTGGGCAGACCCTGGACCTCATCACA
GCCCCCCAGGGCAATGTGGATCTTGGCAGATACACTGAAAAGAGGTACAAATCCATTGTCAAGT
ACAAGACAGCTTTCTACTCCTTCTACCTGCCTATCGCTGCTGCCATGTACATGGCAGGCATTGA
TGGGGAGAAGGAACATGCTAATGCCAAGAAGATCCTGATGCAGATGGGAGAGTTCTTCCAGATT
CAGGATGATTACCTTGACCTCTTTGGCGACCCCAGTGTGACGGGAAAAGTTGGCACTGACATCC
AGGACAACAAGTGCAGCTGGCTGGTGGTTCAGTGTCTGCAACGGGCCACTCCAGAACAGCGCCA
GATCTTGCAGGACAATTATGGGCAGAAGGACGCCAAGAAGGTGGCCCAGGTGAGGGCACTGTAC
GAGGAGATGAATCTACCAGCTGTTTTCTCCAAGTATGAAGAAGACAGTTACATCCACCTTATGA
GTCTCATTGAGCAGTGTGCTGCGCCTCTGCCCCCCACCATCTTCCTGGGGCTGGCCAACAAGAT
CTACAAGCGGAAAAAGTGACCTAGAGACTGCCAGGGCAGGGAGGGAGGGCGGGCTCTCAATAAA
TTATTGTGTAATCTTC

hide sequence

RefSeq Acc Id:

XM_005331352 ⟹ XP_005331409

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405058	25,768,904 - 25,778,024 (+)	NCBI
SpeTri2.0	NW_004936580	4,799,354 - 4,808,406 (+)	NCBI

Sequence:

show sequence

TACTTGACCCAGAGAGCCTAGCGCCGGGCGCGGCCGGATTTTAGGGATACCCCGCCAACCATCC
ACATCAAACGAGACCCGGCGTCCCCGAGCAGAGCACTTTGCTCCTCTCTCAGAATGAACGGAGA
CCAGAAATCAGATGGTTATGCTCAGGAAAAGCAGGATTTCATCCAGCACTTCTCCCAGATAGTC
AAGGTGCTGACTGAAGATGAGATGGGGCACCCAGAGACAGGAGATGCTATTGCTCGACTCAAGG
AGGTCCTGGAATATAATGCCATTGGAGGCAAGTACAACCGGGGTTTGACGGTGGTGGTAGCATT
CCGGGAGCTGGCGGATCCAAGAAAACAGGATGCTGATAGTCTCCAGAGGGCCCTGACAGTGGGC
TGGTGTGTGGAACTGCTTCAAGCTTTCTTCCTGGTGTCAGATGACATCATGGATGCATCCCTTA
CCCGCCGGGGACAGCTCTGCTGGTATCAGAAGCCAGGCATAGGTTTGGATGCCATCAATGACTG
TCTGCTTCTGGAAGCATGTATCTACCGACTGCTGAAGTTCTACTGCCGGGATCAGCCCTACTAT
TTGAACTTGATTGAGCTATTCCTGCAGAGTTCCTATCAGACGGAGATTGGGCAGACCCTGGACC
TCATCACAGCCCCCCAGGGCAATGTGGATCTTGGCAGATACACTGAAAAGAGGTACAAATCCAT
TGTCAAGTACAAGACAGCTTTCTACTCCTTCTACCTGCCTATCGCTGCTGCCATGTACATGGCA
GGCATTGATGGGGAGAAGGAACATGCTAATGCCAAGAAGATCCTGATGCAGATGGGAGAGTTCT
TCCAGATTCAGGATGATTACCTTGACCTCTTTGGCGACCCCAGTGTGACGGGAAAAGTTGGCAC
TGACATCCAGGACAACAAGTGCAGCTGGCTGGTGGTTCAGTGTCTGCAACGGGCCACTCCAGAA
CAGCGCCAGATCTTGCAGGACAATTATGGGCAGAAGGACGCCAAGAAGGTGGCCCAGGTGAGGG
CACTGTACGAGGAGATGAATCTACCAGCTGTTTTCTCCAAGTATGAAGAAGACAGTTACATCCA
CCTTATGAGTCTCATTGAGCAGTGTGCTGCGCCTCTGCCCCCCACCATCTTCCTGGGGCTGGCC
AACAAGATCTACAAGCGGAAAAAGTGACCTAGAGACTGCCAGGGCAGGGAGGGAGGGCGGGCTC
TCAATAAATTATTGTGTAATCTTC

hide sequence

RefSeq Acc Id:

XM_005331353 ⟹ XP_005331410

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405058	25,768,903 - 25,778,024 (+)	NCBI
SpeTri2.0	NW_004936580	4,799,354 - 4,808,406 (+)	NCBI

Sequence:

show sequence

TACTTGACCCAGAGAGCCTAGCGCCGGGCGCGGCCGGATTTTAGGGATACCCCGCCAACCATCC
ACATCAAACGAGACCCGGCGTCCCCGAGCAGAATGAACGGAGACCAGAAATCAGATGGTTATGC
TCAGGAAAAGCAGGATTTCATCCAGCACTTCTCCCAGATAGTCAAGGTGCTGACTGAAGATGAG
ATGGGGCACCCAGAGACAGGAGATGCTATTGCTCGACTCAAGGAGGTCCTGGAATATAATGCCA
TTGGAGGCAAGTACAACCGGGGTTTGACGGTGGTGGTAGCATTCCGGGAGCTGGCGGATCCAAG
AAAACAGGATGCTGATAGTCTCCAGAGGGCCCTGACAGTGGGCTGGTGTGTGGAACTGCTTCAA
GCTTTCTTCCTGGTGTCAGATGACATCATGGATGCATCCCTTACCCGCCGGGGACAGCTCTGCT
GGTATCAGAAGCCAGGCATAGGTTTGGATGCCATCAATGACTGTCTGCTTCTGGAAGCATGTAT
CTACCGACTGCTGAAGTTCTACTGCCGGGATCAGCCCTACTATTTGAACTTGATTGAGCTATTC
CTGCAGAGTTCCTATCAGACGGAGATTGGGCAGACCCTGGACCTCATCACAGCCCCCCAGGGCA
ATGTGGATCTTGGCAGATACACTGAAAAGAGGTACAAATCCATTGTCAAGTACAAGACAGCTTT
CTACTCCTTCTACCTGCCTATCGCTGCTGCCATGTACATGGCAGGCATTGATGGGGAGAAGGAA
CATGCTAATGCCAAGAAGATCCTGATGCAGATGGGAGAGTTCTTCCAGATTCAGGATGATTACC
TTGACCTCTTTGGCGACCCCAGTGTGACGGGAAAAGTTGGCACTGACATCCAGGACAACAAGTG
CAGCTGGCTGGTGGTTCAGTGTCTGCAACGGGCCACTCCAGAACAGCGCCAGATCTTGCAGGAC
AATTATGGGCAGAAGGACGCCAAGAAGGTGGCCCAGGTGAGGGCACTGTACGAGGAGATGAATC
TACCAGCTGTTTTCTCCAAGTATGAAGAAGACAGTTACATCCACCTTATGAGTCTCATTGAGCA
GTGTGCTGCGCCTCTGCCCCCCACCATCTTCCTGGGGCTGGCCAACAAGATCTACAAGCGGAAA
AAGTGACCTAGAGACTGCCAGGGCAGGGAGGGAGGGCGGGCTCTCAATAAATTATTGTGTAATC
TTC

hide sequence

Protein Sequences


Protein RefSeqs	XP_005331408	(Get FASTA)	NCBI Sequence Viewer
	XP_005331409	(Get FASTA)	NCBI Sequence Viewer
	XP_005331410	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000004013.2
GenBank Protein	KAG3281736	(Get FASTA)	NCBI Sequence Viewer
	KAG3281737	(Get FASTA)	NCBI Sequence Viewer
	KAG3281738	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_005331409 ⟸ XM_005331352
- Peptide Label:	isoform X2
- UniProtKB:	I3M4B3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MNGDQKSDGYAQEKQDFIQHFSQIVKVLTEDEMGHPETGDAIARLKEVLEYNAIGGKYNRGLTV VVAFRELADPRKQDADSLQRALTVGWCVELLQAFFLVSDDIMDASLTRRGQLCWYQKPGIGLDA INDCLLLEACIYRLLKFYCRDQPYYLNLIELFLQSSYQTEIGQTLDLITAPQGNVDLGRYTEKR YKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILMQMGEFFQIQDDYLDLFGDPSVTG KVGTDIQDNKCSWLVVQCLQRATPEQRQILQDNYGQKDAKKVAQVRALYEEMNLPAVFSKYEED SYIHLMSLIEQCAAPLPPTIFLGLANKIYKRKK hide sequence

RefSeq Acc Id:	XP_005331410 ⟸ XM_005331353
- Peptide Label:	isoform X2
- UniProtKB:	I3M4B3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MNGDQKSDGYAQEKQDFIQHFSQIVKVLTEDEMGHPETGDAIARLKEVLEYNAIGGKYNRGLTV VVAFRELADPRKQDADSLQRALTVGWCVELLQAFFLVSDDIMDASLTRRGQLCWYQKPGIGLDA INDCLLLEACIYRLLKFYCRDQPYYLNLIELFLQSSYQTEIGQTLDLITAPQGNVDLGRYTEKR YKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILMQMGEFFQIQDDYLDLFGDPSVTG KVGTDIQDNKCSWLVVQCLQRATPEQRQILQDNYGQKDAKKVAQVRALYEEMNLPAVFSKYEED SYIHLMSLIEQCAAPLPPTIFLGLANKIYKRKK hide sequence

RefSeq Acc Id:

XP_005331408 ⟸ XM_005331351

- Peptide Label:

isoform X1

- Sequence:

show sequence

MPLSRWLRSVGVFLLPAPCWAPRERFLGYLRRPSLVHGCPVLGAWHSARCWCQVWTEEPRALCS
SLRMNGDQKSDGYAQEKQDFIQHFSQIVKVLTEDEMGHPETGDAIARLKEVLEYNAIGGKYNRG
LTVVVAFRELADPRKQDADSLQRALTVGWCVELLQAFFLVSDDIMDASLTRRGQLCWYQKPGIG
LDAINDCLLLEACIYRLLKFYCRDQPYYLNLIELFLQSSYQTEIGQTLDLITAPQGNVDLGRYT
EKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILMQMGEFFQIQDDYLDLFGDPS
VTGKVGTDIQDNKCSWLVVQCLQRATPEQRQILQDNYGQKDAKKVAQVRALYEEMNLPAVFSKY
EEDSYIHLMSLIEQCAAPLPPTIFLGLANKIYKRKK

hide sequence

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000004475	UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000004472.3	UniProtKB/TrEMBL
Gene3D-CATH	1.10.600.10	UniProtKB/TrEMBL
InterPro	FPS1-like	UniProtKB/TrEMBL
	Isoprenoid_synthase_dom_sf	UniProtKB/TrEMBL
	Polyprenyl_synt	UniProtKB/TrEMBL
	Polyprenyl_synt_CS	UniProtKB/TrEMBL
NCBI Gene	Fdps	ENTREZGENE
PANTHER	FARNESYL PYROPHOSPHATE SYNTHASE	UniProtKB/TrEMBL
	FARNESYL-PYROPHOSPHATE SYNTHETASE	UniProtKB/TrEMBL
Pfam	polyprenyl_synt	UniProtKB/TrEMBL
PROSITE	POLYPRENYL_SYNTHASE_1	UniProtKB/TrEMBL
	POLYPRENYL_SYNTHASE_2	UniProtKB/TrEMBL
Superfamily-SCOP	SSF48576	UniProtKB/TrEMBL
UniProt	I3M4B3	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB