POLR1C (RNA polymerase I and III subunit C)

Gene: POLR1C (RNA polymerase I and III subunit C) Canis lupus familiaris

Analyze

Symbol:

POLR1C

Name:

RNA polymerase I and III subunit C

RGD ID:

12383480

Description:

ENCODES a protein that exhibits DNA binding (inferred); protein dimerization activity (inferred); RNA polymerase I activity (inferred); INVOLVED IN DNA-templated transcription (inferred); transcription by RNA polymerase I (inferred); transcription by RNA polymerase III (inferred); PARTICIPATES IN RNA polymerase I transcription pathway; RNA polymerase III transcription pathway; ASSOCIATED WITH atherosclerosis (ortholog); breast cancer (ortholog); CAKUT (ortholog); FOUND IN cytoplasm (inferred); DNA-directed RNA polymerase complex (inferred); fibrillar center (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

DNA-directed RNA polymerases I and III subunit RPAC1; polymerase (RNA) I polypeptide C, 30kDa; RNA polymerase I subunit C

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	12	11,978,337 - 11,982,265 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	12	11,978,422 - 12,008,579 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	12	12,004,514 - 12,008,441 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	12	12,461,954 - 12,465,881 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	12	12,462,031 - 12,509,169 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	12	11,987,354 - 11,991,281 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	12	12,074,263 - 12,078,191 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	12	12,167,748 - 12,171,676 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

atherosclerosis (ISO)

breast cancer (ISO)

CAKUT (ISO)

Carey-Fineman-Ziter Syndrome 2 (ISO)

cholangiocarcinoma (ISO)

combined oxidative phosphorylation deficiency (ISO)

combined oxidative phosphorylation deficiency 8 (ISO)

developmental and epileptic encephalopathy (ISO)

diabetic angiopathy (ISO)

dilated cardiomyopathy 1G (ISO)

genetic disease (ISO)

head and neck squamous cell carcinoma (ISO)

Hearing Loss (ISO)

hemolytic disease of the fetus (ISO)

hypertrophic cardiomyopathy 9 (ISO)

hypomyelinating leukodystrophy 11 (ISO)

hypomyelinating leukodystrophy 26 (ISO)

infantile Refsum disease (ISO)

JABERI-ELAHI SYNDROME (ISO)

Lung Agenesis (ISO)

Mandibulofacial Dysostosis (ISO)

neurodegeneration with brain iron accumulation (ISO)

primary ciliary dyskinesia (ISO)

primary ciliary dyskinesia 12 (ISO)

progressive leukoencephalopathy with ovarian failure (ISO)

spondyloepimetaphyseal dysplasia with joint laxity (ISO)

Treacher Collins syndrome 3 (ISO)

xeroderma pigmentosum (ISO)

xeroderma pigmentosum variant type (ISO)

Zellweger syndrome (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

DNA-templated transcription (IEA)

transcription by RNA polymerase I (IEA)

transcription by RNA polymerase III (IEA)

Cellular Component

cytoplasm (IEA)

DNA-directed RNA polymerase complex (IEA)

fibrillar center (IEA)

nucleoplasm (IEA)

nucleus (IEA)

RNA polymerase I complex (IEA)

RNA polymerase III complex (IEA)

Molecular Function

DNA binding (IEA)

protein binding (ISO)

protein dimerization activity (IEA)

RNA polymerase I activity (IEA)

RNA polymerase III activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

RNA polymerase I transcription pathway (ISO)

RNA polymerase III transcription pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

POLR1C
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	12	11,978,337 - 11,982,265 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	12	11,978,422 - 12,008,579 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	12	12,004,514 - 12,008,441 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	12	12,461,954 - 12,465,881 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	12	12,462,031 - 12,509,169 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	12	11,987,354 - 11,991,281 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	12	12,074,263 - 12,078,191 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	12	12,167,748 - 12,171,676 (+)	NCBI		UU_Cfam_GSD_1.0

POLR1C
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	43,517,089 - 44,461,400 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	43,509,702 - 43,562,419 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	43,484,827 - 44,429,137 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	43,592,769 - 43,605,092 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	6	45,036,412 - 45,048,735 (+)	NCBI		Celera
Cytogenetic Map	6	p21.1	NCBI
HuRef	6	43,202,730 - 43,208,225 (+)	NCBI		HuRef
CHM1_1	6	43,487,909 - 43,492,383 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	6	43,345,828 - 44,296,039 (+)	NCBI		T2T-CHM13v2.0

Polr1c
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	46,554,846 - 46,558,971 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	46,554,846 - 46,558,980 (-)	Ensembl		GRCm39 Ensembl
GRCm38	17	46,243,920 - 46,248,045 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	46,243,920 - 46,248,054 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	46,380,869 - 46,384,994 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	17	45,707,509 - 45,711,545 (-)	NCBI		MGSCv36	mm8
Celera	17	49,677,058 - 49,681,183 (-)	NCBI		Celera
Cytogenetic Map	17	C	NCBI
cM Map	17	22.9	NCBI

Polr1c
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	22,233,318 - 22,237,430 (+)	NCBI		GRCr8
mRatBN7.2	9	14,735,740 - 14,739,852 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	14,735,714 - 14,739,852 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	23,319,979 - 23,324,091 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	28,382,463 - 28,386,575 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	26,683,367 - 26,687,479 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	17,120,759 - 17,124,871 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	17,120,759 - 17,124,871 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	16,017,436 - 16,021,548 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	10,298,309 - 10,302,421 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	10,295,630 - 10,299,743 (+)	NCBI
Celera	9	12,483,058 - 12,487,170 (+)	NCBI		Celera
Cytogenetic Map	9	q12	NCBI

Polr1c
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955437	9,346,397 - 9,350,591 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955437	9,346,397 - 9,350,591 (+)	NCBI	ChiLan1.0	ChiLan1.0

POLR1C
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	58,009,906 - 58,029,793 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	53,879,703 - 53,899,579 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	43,101,771 - 43,121,460 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	44,399,936 - 44,404,420 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	44,395,787 - 44,412,257 (+)	Ensembl	panpan1.1		panPan2

Polr1c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	47,472,764 - 47,476,677 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936476	16,480,835 - 16,487,424 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936476	16,483,203 - 16,487,360 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

POLR1C
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	38,507,073 - 38,537,943 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	38,511,521 - 38,531,938 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	44,092,595 - 44,111,879 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

POLR1C
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	17	28,637,868 - 28,649,898 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666044	43,572,869 - 43,577,363 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Polr1c
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624754	16,122,935 - 16,136,395 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624754	16,125,322 - 16,129,339 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in POLR1C
33 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	reproductive system	respiratory system	adipose tissue
High
Medium	5	5	18	2	2	2	6		12	8	10	6
Low			4	4	4	4		6
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_038491905	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038554170	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038618034	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038683631	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_532147	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000123	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000357	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCAFT00000002964 ⟹ ENSCAFP00000002749

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	12	11,978,422 - 11,982,264 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00000070259 ⟹ ENSCAFP00000054568

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	12	11,978,422 - 12,008,579 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00000086275 ⟹ ENSCAFP00000056632

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	12	11,978,422 - 11,989,382 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00000090224 ⟹ ENSCAFP00000056225

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	12	11,978,422 - 11,982,264 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845016839 ⟹ ENSCAFP00845013097

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	12	12,462,031 - 12,509,169 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845016884 ⟹ ENSCAFP00845013138

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	12	12,462,031 - 12,509,169 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845016916 ⟹ ENSCAFP00845013167

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	12	12,462,031 - 12,492,222 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845016951 ⟹ ENSCAFP00845013198

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	12	12,462,031 - 12,472,999 (+)	Ensembl

RefSeq Acc Id:

XM_038491905 ⟹ XP_038347833

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	12	11,987,354 - 11,991,281 (+)	NCBI

RefSeq Acc Id:

XM_038554170 ⟹ XP_038410098

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	12	12,167,748 - 12,171,676 (+)	NCBI

RefSeq Acc Id:

XM_038618034 ⟹ XP_038473962

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	12	12,074,263 - 12,078,191 (+)	NCBI

RefSeq Acc Id:

XM_038683631 ⟹ XP_038539559

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	12	12,461,954 - 12,465,881 (+)	NCBI

RefSeq Acc Id:

XM_532147 ⟹ XP_532147

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	12	11,978,337 - 11,982,265 (+)	NCBI
Dog10K_Boxer_Tasha	12	12,004,514 - 12,008,441 (+)	NCBI

Sequence:

show sequence

TCCCGGGAGGCGGTGCGTTGCCATGGAGACGAAGGAGGGCGACTGGGACGCGCGCGCCAGTTTG
CTGCCCTAGTCACGTGGAGGGGTAGAAGATGGCGGCCGCCCAGGCGGTGCAAGAGATGCGGACC
CGCGTGGTTCTAGGGGAGTTCGGGGTTCGCAATGTTCATACCACCGACTTTCCCGGTAACTATT
CCGGCTATGATGATGCCTGGGACCAAGACCGCTTCGAGAAGAATTTCCGTGTGGATGTAGTGCA
CATGGATGAAAACTCATTGGAGTTCGACATGGTGGGAATTGATGCAGCCATTGCCAATGCTTTT
CGACGCATTTTATTAGCTGAGGTGCCAACCATGGCTGTGGAAAAGGTCCTGGTGTACAACAACA
CATCCATTGTCCAGGATGAGATCCTTGCTCATCGCTTGGGGCTTATTCCCATTCATGCTGATCC
TCGTCTGTTTGAGTATCGGAACCAAGGGGATGATGAAGGCACAGAGATAGATACTCTGCAGTTT
CGGCTTCAAGTCAGGTGCACACGGAACCCCCATGCTGCTAAAGATTCCTCTGACCCCAATGAAC
TCTATGTGAACCACAAAGTGTACTCCAGGCACATGACATGGGTGCCCCTGGGGAATCAGGCTGA
CCTCTTCCCAGAGGGCACGATCAGACCCGTGCATGATGATATCCTCATTGCTCAGCTGAGGCCT
GGCCAGGAGATTGACCTACTCATGCACTGTGTCAAGGGCATTGGAAAAGATCATGCCAAGTTTT
CACCTGTGGCAACAGCCAGTTACAGGCTCCTGCCAGACATCACCCTGCTTGAGCCCGTGGAAGG
GGATGCAGCGGAGGAGCTGAGCCGATGCTTCTCACCTGGTGTCATTGAGGTGCAGGAAGTCCAA
GGTAAAAAGGTGGCCAGGGTGGCCAATCCCCGGCTAGATACCTTCAGCAGGGAAGTGTTCCGGA
AGGAGAAGCTGAAGAAGGTTGTCCGCCTTGCGCGGGTTCGAGACCATTACATCTTCTCTGTCGA
GTCAACAGGGGTGTTACCACCAGATGTGCTAGTGAGTGAAGCCATCAAGGTGCTGATGGGGAAG
TGCCGACGGTTCTTGGATGAACTGGATGCAGTTCAGATGGACTGAGGTTTCCACCGGACTTACT
GGCATGGCTGGCCTCGGATGCTCCTGAGCCAAGCTGAAGATCTTGGGTCCTGACCTGACCTCAC
AGGCCTGCTAGAGTCTGGTGTGACTGGAGATCCTGGGTTTTCTGGGATAGTTCCAGTCTTATTT
TCAGTCAGTAGGTTTTGCTAAATGTGCCACAAAATGTGACCTCATGCCTTTGTAAGGCCTTAAT
GTAAATAAATTCACATCCAAATAAAGATCCTCTTGTCAGAGACTA

hide sequence

Protein Sequences


Protein RefSeqs	XP_038347833	(Get FASTA)	NCBI Sequence Viewer
	XP_038410098	(Get FASTA)	NCBI Sequence Viewer
	XP_038473962	(Get FASTA)	NCBI Sequence Viewer
	XP_038539559	(Get FASTA)	NCBI Sequence Viewer
	XP_532147	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000002749.3
	ENSCAFP00000054568.1
	ENSCAFP00000056225.1
	ENSCAFP00000056632.1
	ENSCAFP00030018356.1
	ENSCAFP00030018389.1
	ENSCAFP00030018482.1
	ENSCAFP00030018518.1
	ENSCAFP00040013373.1
	ENSCAFP00040013387.1
	ENSCAFP00040013436.1
	ENSCAFP00040013453.1
	ENSCAFP00845013097
	ENSCAFP00845013097.1
	ENSCAFP00845013138.1
	ENSCAFP00845013167.1
	ENSCAFP00845013198.1

RefSeq Acc Id:

XP_532147 ⟸ XM_532147

- UniProtKB:

A0A8C0KFY0 (UniProtKB/TrEMBL), A0A8C0QML3 (UniProtKB/TrEMBL), A0A8I3RVA8 (UniProtKB/TrEMBL), A0A8C0QJZ9 (UniProtKB/TrEMBL), A0A8I3NC91 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAAAQAVQEMRTRVVLGEFGVRNVHTTDFPGNYSGYDDAWDQDRFEKNFRVDVVHMDENSLEFD
MVGIDAAIANAFRRILLAEVPTMAVEKVLVYNNTSIVQDEILAHRLGLIPIHADPRLFEYRNQG
DDEGTEIDTLQFRLQVRCTRNPHAAKDSSDPNELYVNHKVYSRHMTWVPLGNQADLFPEGTIRP
VHDDILIAQLRPGQEIDLLMHCVKGIGKDHAKFSPVATASYRLLPDITLLEPVEGDAAEELSRC
FSPGVIEVQEVQGKKVARVANPRLDTFSREVFRKEKLKKVVRLARVRDHYIFSVESTGVLPPDV
LVSEAIKVLMGKCRRFLDELDAVQMD

hide sequence

RefSeq Acc Id:

ENSCAFP00000054568 ⟸ ENSCAFT00000070259

RefSeq Acc Id:

ENSCAFP00000056632 ⟸ ENSCAFT00000086275

RefSeq Acc Id:

ENSCAFP00000056225 ⟸ ENSCAFT00000090224

RefSeq Acc Id:

ENSCAFP00000002749 ⟸ ENSCAFT00000002964

RefSeq Acc Id:

XP_038347833 ⟸ XM_038491905

RefSeq Acc Id:

XP_038473962 ⟸ XM_038618034

RefSeq Acc Id:	XP_038539559 ⟸ XM_038683631
- UniProtKB:	A0A8C0KFY0 (UniProtKB/TrEMBL), A0A8C0QML3 (UniProtKB/TrEMBL), A0A8I3RVA8 (UniProtKB/TrEMBL), A0A8C0QJZ9 (UniProtKB/TrEMBL), A0A8I3NC91 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038410098 ⟸ XM_038554170
- UniProtKB:	A0A8C0KFY0 (UniProtKB/TrEMBL), A0A8C0QJZ9 (UniProtKB/TrEMBL), A0A8C0QML3 (UniProtKB/TrEMBL), A0A8I3NC91 (UniProtKB/TrEMBL), A0A8I3RVA8 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCAFP00845013138 ⟸ ENSCAFT00845016884

RefSeq Acc Id:

ENSCAFP00845013097 ⟸ ENSCAFT00845016839

RefSeq Acc Id:

ENSCAFP00845013167 ⟸ ENSCAFT00845016916

RefSeq Acc Id:

ENSCAFP00845013198 ⟸ ENSCAFT00845016951

Protein Domains

DNA-directed RNA polymerase RpoA/D/Rpb3-type

Promoters

RGD ID:

13685438

Promoter ID:

EPDNEW_C3506

Type:

multiple initiation site

Name:

POLR1C_1

Description:

RNA polymerase I subunit C

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	12	11,978,424 - 11,978,484	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000001872	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030011349	UniProtKB/TrEMBL
	ENSCAFG00040008228	UniProtKB/TrEMBL
	ENSCAFG00845009541	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000002964.5	UniProtKB/TrEMBL
	ENSCAFT00000070259.2	UniProtKB/TrEMBL
	ENSCAFT00000086275.2	UniProtKB/TrEMBL
	ENSCAFT00000090224.2	UniProtKB/TrEMBL
	ENSCAFT00030021049.1	UniProtKB/TrEMBL
	ENSCAFT00030021091.1	UniProtKB/TrEMBL
	ENSCAFT00030021197.1	UniProtKB/TrEMBL
	ENSCAFT00030021245.1	UniProtKB/TrEMBL
	ENSCAFT00040015426.1	UniProtKB/TrEMBL
	ENSCAFT00040015440.1	UniProtKB/TrEMBL
	ENSCAFT00040015498.1	UniProtKB/TrEMBL
	ENSCAFT00040015519.1	UniProtKB/TrEMBL
	ENSCAFT00845016839	ENTREZGENE
	ENSCAFT00845016839.1	UniProtKB/TrEMBL
	ENSCAFT00845016884.1	UniProtKB/TrEMBL
	ENSCAFT00845016916.1	UniProtKB/TrEMBL
	ENSCAFT00845016951.1	UniProtKB/TrEMBL
Gene3D-CATH	2.170.120.12	UniProtKB/TrEMBL
	3.30.1360.10	UniProtKB/TrEMBL
InterPro	DNA-dir_RNA_pol_30-40kDasu_CS	UniProtKB/TrEMBL
	DNA-dir_RNA_pol_insert	UniProtKB/TrEMBL
	DNA-dir_RNA_pol_RpoA/D/Rpb3	UniProtKB/TrEMBL
	RBP11-like	UniProtKB/TrEMBL
	RNAP_Rpo3/Rpb3/RPAC1	UniProtKB/TrEMBL
	RNAPI/III_AC40	UniProtKB/TrEMBL
	RNApol_insert_sf	UniProtKB/TrEMBL
KEGG Report	cfa:474912	UniProtKB/TrEMBL
NCBI Gene	POLR1C	ENTREZGENE
PANTHER	DNA-DIRECTED RNA POLYMERASE	UniProtKB/TrEMBL
	PTHR11800:SF13	UniProtKB/TrEMBL
Pfam	RNA_pol_A_bac	UniProtKB/TrEMBL
	RNA_pol_L	UniProtKB/TrEMBL
PROSITE	RNA_POL_D_30KD	UniProtKB/TrEMBL
SMART	RPOLD	UniProtKB/TrEMBL
Superfamily-SCOP	SSF55257	UniProtKB/TrEMBL
	SSF56553	UniProtKB/TrEMBL
UniProt	A0A8C0KFY0	ENTREZGENE
	A0A8C0N4L2_CANLF	UniProtKB/TrEMBL
	A0A8C0QFB8_CANLF	UniProtKB/TrEMBL
	A0A8C0QJZ9	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0QML3	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3N871_CANLF	UniProtKB/TrEMBL
	A0A8I3N8B1_CANLF	UniProtKB/TrEMBL
	A0A8I3NC91	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3RVA8	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:44790	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2018-03-13	POLR1C	RNA polymerase I and III subunit C		RNA polymerase I subunit C	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

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RGD Manual Annotations