CLDN34 (claudin 34) - Rat Genome Database

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Gene: CLDN34 (claudin 34) Canis lupus familiaris
Analyze
Symbol: CLDN34
Name: claudin 34
RGD ID: 12303073
Description: ENCODES a protein that exhibits structural molecule activity (inferred); INVOLVED IN bicellular tight junction assembly (inferred); cell adhesion (inferred); ASSOCIATED WITH autistic disorder (ortholog); FOUND IN bicellular tight junction (inferred); membrane (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: claudin-34
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X6,643,967 - 6,657,995 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX6,649,645 - 6,658,010 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX6,600,165 - 6,614,221 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X6,590,926 - 6,604,982 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1X6,581,258 - 6,595,313 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X6,616,449 - 6,630,505 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X6,606,843 - 6,620,899 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
CLDN34
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X6,643,967 - 6,657,995 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX6,649,645 - 6,658,010 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX6,600,165 - 6,614,221 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X6,590,926 - 6,604,982 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1X6,581,258 - 6,595,313 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X6,616,449 - 6,630,505 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X6,606,843 - 6,620,899 (+)NCBIUU_Cfam_GSD_1.0
CLDN34
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X9,967,358 - 9,968,352 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX9,967,358 - 9,968,352 (+)EnsemblGRCh38hg38GRCh38
GRCh37X9,935,398 - 9,936,392 (+)NCBIGRCh37GRCh37hg19GRCh37
CeleraX14,106,681 - 14,107,325 (+)NCBICelera
Cytogenetic MapXp22.2NCBI
HuRefX7,767,169 - 7,767,813 (+)NCBIHuRef
CHM1_1X9,965,818 - 9,966,462 (+)NCBICHM1_1
T2T-CHM13v2.0X9,549,941 - 9,550,935 (+)NCBIT2T-CHM13v2.0
Cldn34a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X151,320,524 - 151,347,194 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX151,320,497 - 151,347,193 (+)EnsemblGRCm39 Ensembl
GRCm38X152,537,528 - 152,564,198 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX152,537,501 - 152,564,197 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X148,997,877 - 148,998,512 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X148,997,877 - 148,998,512 (+)NCBIMGSCv36mm8
CeleraX136,689,100 - 136,689,735 (-)NCBICelera
Cytogenetic MapXF3NCBI
cM MapX68.46NCBI
Cldn34a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X25,164,586 - 25,233,074 (+)NCBIGRCr8
mRatBN7.2X21,717,101 - 21,737,363 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX21,736,419 - 21,737,054 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX22,638,720 - 22,639,355 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X26,059,696 - 26,060,331 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X22,318,369 - 22,319,004 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X23,371,171 - 23,415,287 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX23,414,354 - 23,414,989 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X23,785,424 - 23,832,886 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X42,210,493 - 42,211,128 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX22,158,824 - 22,159,459 (+)NCBICelera
Cytogenetic MapXq13NCBI
Cldn34
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555443,190,014 - 3,190,573 (+)NCBIChiLan1.0ChiLan1.0
CLDN34
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X11,762,676 - 11,773,083 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X11,766,343 - 11,776,750 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X2,591,451 - 2,599,328 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X9,850,227 - 9,850,932 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX9,850,227 - 9,850,871 (+)Ensemblpanpan1.1panPan2
Cldn34
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049534,336,486 - 4,346,248 (+)NCBIHiC_Itri_2
SpeTri2.0NW_00493664430,632 - 31,270 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CLDN34
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X8,416,983 - 8,423,683 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605610,097,322 - 10,098,753 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cldn34
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462478212,756,563 - 12,790,973 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CLDN34
351 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 1 8
Low 5 5 21 6 5 6 6 12 10 4
Below cutoff 1 5 2

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003435456 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005641097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022415925 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022415926 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038449370 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038449371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038449372 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038449373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038522792 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038522793 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038522794 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038522795 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038586794 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038586795 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038586796 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038586797 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038651299 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038651300 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038651301 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038651302 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000146 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000368 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000110 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000175 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000039 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSCAFT00000018100   ⟹   ENSCAFP00000016764
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 EnsemblX6,649,645 - 6,658,010 (+)Ensembl
RefSeq Acc Id: XM_003435456   ⟹   XP_003435504
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1X6,643,967 - 6,657,995 (+)NCBI
Dog10K_Boxer_TashaX6,600,165 - 6,614,221 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005641097   ⟹   XP_005641154
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1X6,643,967 - 6,657,995 (+)NCBI
Dog10K_Boxer_TashaX6,600,165 - 6,614,221 (+)NCBI
Sequence:
RefSeq Acc Id: XM_022415925   ⟹   XP_022271633
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1X6,647,345 - 6,657,995 (+)NCBI
Dog10K_Boxer_TashaX6,603,575 - 6,614,221 (+)NCBI
Sequence:
RefSeq Acc Id: XM_022415926   ⟹   XP_022271634
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1X6,647,615 - 6,657,995 (+)NCBI
Dog10K_Boxer_TashaX6,605,848 - 6,614,221 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038449370   ⟹   XP_038305298
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0X6,594,336 - 6,604,982 (+)NCBI
RefSeq Acc Id: XM_038449371   ⟹   XP_038305299
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0X6,596,609 - 6,604,982 (+)NCBI
RefSeq Acc Id: XM_038449372   ⟹   XP_038305300
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0X6,590,926 - 6,604,982 (+)NCBI
RefSeq Acc Id: XM_038449373   ⟹   XP_038305301
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0X6,590,926 - 6,604,982 (+)NCBI
RefSeq Acc Id: XM_038522792   ⟹   XP_038378720
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1X6,584,668 - 6,595,313 (+)NCBI
RefSeq Acc Id: XM_038522793   ⟹   XP_038378721
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1X6,586,941 - 6,595,313 (+)NCBI
RefSeq Acc Id: XM_038522794   ⟹   XP_038378722
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1X6,581,258 - 6,595,313 (+)NCBI
RefSeq Acc Id: XM_038522795   ⟹   XP_038378723
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1X6,581,258 - 6,595,313 (+)NCBI
RefSeq Acc Id: XM_038586794   ⟹   XP_038442722
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0X6,610,253 - 6,620,899 (+)NCBI
RefSeq Acc Id: XM_038586795   ⟹   XP_038442723
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0X6,612,526 - 6,620,899 (+)NCBI
RefSeq Acc Id: XM_038586796   ⟹   XP_038442724
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0X6,606,843 - 6,620,899 (+)NCBI
RefSeq Acc Id: XM_038586797   ⟹   XP_038442725
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0X6,606,843 - 6,620,899 (+)NCBI
RefSeq Acc Id: XM_038651299   ⟹   XP_038507227
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0X6,619,859 - 6,630,505 (+)NCBI
RefSeq Acc Id: XM_038651300   ⟹   XP_038507228
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0X6,622,132 - 6,630,505 (+)NCBI
RefSeq Acc Id: XM_038651301   ⟹   XP_038507229
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0X6,616,449 - 6,630,505 (+)NCBI
RefSeq Acc Id: XM_038651302   ⟹   XP_038507230
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0X6,616,449 - 6,630,505 (+)NCBI
RefSeq Acc Id: XP_005641154   ⟸   XM_005641097
- UniProtKB: A0A8C0RG35 (UniProtKB/TrEMBL),   A0A8C0QTT3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003435504   ⟸   XM_003435456
- UniProtKB: A0A8C0RG35 (UniProtKB/TrEMBL),   A0A8C0QTT3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022271633   ⟸   XM_022415925
- UniProtKB: A0A8C0RG35 (UniProtKB/TrEMBL),   A0A8C0QTT3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022271634   ⟸   XM_022415926
- UniProtKB: A0A8C0RG35 (UniProtKB/TrEMBL),   A0A8C0QTT3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000016764   ⟸   ENSCAFT00000018100
RefSeq Acc Id: XP_038378722   ⟸   XM_038522794
RefSeq Acc Id: XP_038378723   ⟸   XM_038522795
RefSeq Acc Id: XP_038378720   ⟸   XM_038522792
RefSeq Acc Id: XP_038378721   ⟸   XM_038522793
RefSeq Acc Id: XP_038507229   ⟸   XM_038651301
RefSeq Acc Id: XP_038507230   ⟸   XM_038651302
RefSeq Acc Id: XP_038507227   ⟸   XM_038651299
RefSeq Acc Id: XP_038507228   ⟸   XM_038651300
RefSeq Acc Id: XP_038305300   ⟸   XM_038449372
- UniProtKB: A0A8C0RG35 (UniProtKB/TrEMBL),   A0A8C0QTT3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038305301   ⟸   XM_038449373
- UniProtKB: A0A8C0RG35 (UniProtKB/TrEMBL),   A0A8C0QTT3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038305298   ⟸   XM_038449370
- UniProtKB: A0A8C0RG35 (UniProtKB/TrEMBL),   A0A8C0QTT3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038305299   ⟸   XM_038449371
- UniProtKB: A0A8C0RG35 (UniProtKB/TrEMBL),   A0A8C0QTT3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038442724   ⟸   XM_038586796
- UniProtKB: A0A8C0QTT3 (UniProtKB/TrEMBL),   A0A8C0RG35 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038442725   ⟸   XM_038586797
- UniProtKB: A0A8C0QTT3 (UniProtKB/TrEMBL),   A0A8C0RG35 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038442722   ⟸   XM_038586794
- UniProtKB: A0A8C0QTT3 (UniProtKB/TrEMBL),   A0A8C0RG35 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038442723   ⟸   XM_038586795
- UniProtKB: A0A8C0QTT3 (UniProtKB/TrEMBL),   A0A8C0RG35 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000011393 Ensembl
  ENSCAFG00030009007 UniProtKB/TrEMBL
  ENSCAFG00040014503 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00030016612.1 UniProtKB/TrEMBL
  ENSCAFT00040026710.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.140.150 UniProtKB/TrEMBL
InterPro Claudin UniProtKB/TrEMBL
  PMP22/EMP/MP20/Claudin UniProtKB/TrEMBL
KEGG Report cfa:100686536 UniProtKB/TrEMBL
NCBI Gene CLDN34 ENTREZGENE
PANTHER CLAUDIN-34 UniProtKB/TrEMBL
  PTHR12002 UniProtKB/TrEMBL
Pfam Claudin_2 UniProtKB/TrEMBL
PRINTS CLAUDIN UniProtKB/TrEMBL
UniProt A0A8C0QTT3 ENTREZGENE
  A0A8C0RG35 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:39320 ENTREZGENE