TRANK1 (tetratricopeptide repeat and ankyrin repeat containing 1) - Rat Genome Database

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Gene: TRANK1 (tetratricopeptide repeat and ankyrin repeat containing 1) Canis lupus familiaris
Analyze
Symbol: TRANK1
Name: tetratricopeptide repeat and ankyrin repeat containing 1
RGD ID: 12278740
Description: INVOLVED IN intracellular signal transduction (inferred); ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); bipolar disorder (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: TPR and ankyrin repeat-containing protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1236,749,817 - 6,849,113 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl236,631,276 - 6,849,034 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha236,789,473 - 6,869,908 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0237,034,999 - 7,115,474 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl236,946,464 - 7,134,352 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1236,854,618 - 6,935,467 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0236,997,235 - 7,077,671 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0236,987,132 - 7,067,610 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
TRANK1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1236,749,817 - 6,849,113 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl236,631,276 - 6,849,034 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha236,789,473 - 6,869,908 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0237,034,999 - 7,115,474 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl236,946,464 - 7,134,352 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1236,854,618 - 6,935,467 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0236,997,235 - 7,077,671 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0236,987,132 - 7,067,610 (-)NCBIUU_Cfam_GSD_1.0
TRANK1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38336,826,819 - 36,945,744 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl336,826,819 - 36,945,057 (-)EnsemblGRCh38hg38GRCh38
GRCh37336,868,310 - 36,986,545 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36336,843,315 - 36,877,415 (-)NCBINCBI36Build 36hg18NCBI36
Celera336,811,078 - 36,929,308 (-)NCBICelera
Cytogenetic Map3p22.2NCBI
HuRef336,808,964 - 36,927,088 (-)NCBIHuRef
CHM1_1336,818,551 - 36,938,172 (-)NCBICHM1_1
T2T-CHM13v2.0336,828,168 - 36,947,110 (-)NCBIT2T-CHM13v2.0
Trank1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399111,140,351 - 111,224,843 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9111,140,807 - 111,224,843 (+)EnsemblGRCm39 Ensembl
GRCm389111,311,283 - 111,395,775 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9111,311,739 - 111,395,775 (+)EnsemblGRCm38mm10GRCm38
MGSCv379111,214,243 - 111,298,279 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369111,219,636 - 111,240,591 (+)NCBIMGSCv36mm8
Celera9111,038,156 - 111,123,540 (+)NCBICelera
Cytogenetic Map9F3NCBI
cM Map960.95NCBI
Trank1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88120,153,381 - 120,233,879 (+)NCBIGRCr8
mRatBN7.28111,275,973 - 111,355,491 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8111,276,354 - 111,355,092 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8116,892,440 - 116,970,177 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08115,091,671 - 115,169,416 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08112,934,500 - 113,012,248 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08119,566,509 - 119,644,249 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8119,566,509 - 119,644,249 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08118,916,156 - 118,993,803 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48115,701,554 - 115,781,013 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera8110,557,993 - 110,635,930 (+)NCBICelera
Cytogenetic Map8q32NCBI
Trank1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554213,707,510 - 3,853,868 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554213,707,510 - 3,852,886 (-)NCBIChiLan1.0ChiLan1.0
TRANK1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2236,788,485 - 36,907,530 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1336,793,249 - 36,912,330 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0336,732,939 - 36,852,023 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1337,023,455 - 37,141,982 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl337,024,909 - 37,102,299 (-)Ensemblpanpan1.1panPan2
Trank1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118193,265,171 - 193,365,150 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647326,403,681 - 26,482,721 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647326,403,786 - 26,481,284 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRANK1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1321,938,966 - 22,023,156 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11321,913,400 - 22,023,165 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21323,906,064 - 23,912,672 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TRANK1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1152,464,289 - 2,583,314 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl152,502,023 - 2,581,141 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606311,201,749 - 11,319,415 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Trank1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478814,922,497 - 15,065,624 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478814,926,685 - 15,035,745 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in TRANK1
1109 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 11
Low 5 15 6 6 6 6 1 8 10 6
Below cutoff 5 2 6

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000007678   ⟹   ENSCAFP00000007112
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl236,750,905 - 6,830,392 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000036550   ⟹   ENSCAFP00000031944
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl236,750,905 - 6,849,034 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000043491   ⟹   ENSCAFP00000041818
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl236,750,905 - 6,830,392 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000043893   ⟹   ENSCAFP00000038945
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl236,631,276 - 6,687,992 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000077905   ⟹   ENSCAFP00000051370
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl236,631,276 - 6,830,392 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000088109   ⟹   ENSCAFP00000050681
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl236,750,905 - 6,830,392 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845046448   ⟹   ENSCAFP00845036466
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl236,946,464 - 7,115,440 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845046674   ⟹   ENSCAFP00845036633
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl237,035,005 - 7,134,352 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845046877   ⟹   ENSCAFP00845036765
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl237,035,005 - 7,115,611 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845047062   ⟹   ENSCAFP00845036934
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl237,035,005 - 7,115,440 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845047193   ⟹   ENSCAFP00845037036
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl237,035,005 - 7,115,440 (-)Ensembl
RefSeq Acc Id: XM_005634226   ⟹   XP_005634283
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1236,749,817 - 6,849,113 (-)NCBI
Dog10K_Boxer_Tasha236,789,473 - 6,869,908 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038431816   ⟹   XP_038287744
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0237,034,999 - 7,115,474 (-)NCBI
RefSeq Acc Id: XM_038431817   ⟹   XP_038287745
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0237,034,999 - 7,115,474 (-)NCBI
RefSeq Acc Id: XM_038507138   ⟹   XP_038363066
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1236,854,618 - 6,935,467 (-)NCBI
RefSeq Acc Id: XM_038570369   ⟹   XP_038426297
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0236,987,132 - 7,067,610 (-)NCBI
RefSeq Acc Id: XM_038634558   ⟹   XP_038490486
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0236,997,235 - 7,077,671 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_005634283   ⟸   XM_005634226
- Peptide Label: isoform X1
- UniProtKB: A0A8C0JJN8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000050681   ⟸   ENSCAFT00000088109
RefSeq Acc Id: ENSCAFP00000038945   ⟸   ENSCAFT00000043893
RefSeq Acc Id: ENSCAFP00000051370   ⟸   ENSCAFT00000077905
RefSeq Acc Id: ENSCAFP00000041818   ⟸   ENSCAFT00000043491
RefSeq Acc Id: ENSCAFP00000031944   ⟸   ENSCAFT00000036550
RefSeq Acc Id: ENSCAFP00000007112   ⟸   ENSCAFT00000007678
RefSeq Acc Id: XP_038363066   ⟸   XM_038507138
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038490486   ⟸   XM_038634558
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038287745   ⟸   XM_038431817
- Peptide Label: isoform X2
- UniProtKB: A0A8C0MA15 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038287744   ⟸   XM_038431816
- Peptide Label: isoform X1
- UniProtKB: A0A8C0JJN8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038426297   ⟸   XM_038570369
- Peptide Label: isoform X1
- UniProtKB: A0A8C0JJN8 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845036934   ⟸   ENSCAFT00845047062
RefSeq Acc Id: ENSCAFP00845036466   ⟸   ENSCAFT00845046448
RefSeq Acc Id: ENSCAFP00845036765   ⟸   ENSCAFT00845046877
RefSeq Acc Id: ENSCAFP00845036633   ⟸   ENSCAFT00845046674
RefSeq Acc Id: ENSCAFP00845037036   ⟸   ENSCAFT00845047193
Protein Domains
Doublecortin

Promoters
RGD ID:13687390
Promoter ID:EPDNEW_C5458
Type:single initiation site
Name:TRANK1_1
Description:tetratricopeptide repeat and ankyrin repeat containing 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1236,849,012 - 6,849,072EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000004776 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030004832 UniProtKB/TrEMBL
  ENSCAFG00845026194 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000007678.6 UniProtKB/TrEMBL
  ENSCAFT00000036550.4 UniProtKB/TrEMBL
  ENSCAFT00030009820.1 UniProtKB/TrEMBL
  ENSCAFT00845046448.1 UniProtKB/TrEMBL
  ENSCAFT00845046674 ENTREZGENE
  ENSCAFT00845046674.1 UniProtKB/TrEMBL
  ENSCAFT00845046877.1 UniProtKB/TrEMBL
  ENSCAFT00845047062.1 UniProtKB/TrEMBL
  ENSCAFT00845047193.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.10 UniProtKB/TrEMBL
  1.25.40.20 UniProtKB/TrEMBL
  3.10.20.230 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro Ankyrin_rpt UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/TrEMBL
  Doublecortin_dom UniProtKB/TrEMBL
  Doublecortin_dom_sf UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/TrEMBL
  TPR_repeat UniProtKB/TrEMBL
  TRANK1 UniProtKB/TrEMBL
NCBI Gene TRANK1 ENTREZGENE
PANTHER PTHR21529 UniProtKB/TrEMBL
  TPR AND ANKYRIN REPEAT-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
Pfam DCX UniProtKB/TrEMBL
PROSITE PS50309 UniProtKB/TrEMBL
SMART ANK UniProtKB/TrEMBL
  DCX UniProtKB/TrEMBL
  TPR UniProtKB/TrEMBL
Superfamily-SCOP SSF48403 UniProtKB/TrEMBL
  SSF48452 UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
  SSF89837 UniProtKB/TrEMBL
UniProt A0A8C0JJN8 ENTREZGENE
  A0A8C0MA15 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3PPJ8_CANLF UniProtKB/TrEMBL
  A0A8I3PV15_CANLF UniProtKB/TrEMBL
  A0A8I3PWQ6_CANLF UniProtKB/TrEMBL
  A0A8I3Q9B2_CANLF UniProtKB/TrEMBL
  A0A8I3SAC9_CANLF UniProtKB/TrEMBL
  A0A8P0N7I0_CANLF UniProtKB/TrEMBL
  A0A8P0NMH6_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:47775 ENTREZGENE