STT3B (STT3 oligosaccharyltransferase complex catalytic subunit B) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: STT3B (STT3 oligosaccharyltransferase complex catalytic subunit B) Canis lupus familiaris
Analyze
Symbol: STT3B
Name: STT3 oligosaccharyltransferase complex catalytic subunit B
RGD ID: 12117122
Description: ENCODES a protein that exhibits dolichyl-diphosphooligosaccharide-protein glycotransferase activity; INVOLVED IN protein N-linked glycosylation via asparagine; co-translational protein modification (ortholog); ERAD pathway (ortholog); ASSOCIATED WITH congenital disorder of glycosylation Ix (ortholog); FOUND IN oligosaccharyltransferase I complex; oligosaccharyltransferase II complex; oligosaccharyltransferase complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B; oligosaccharyl transferase subunit STT3B; STT3, subunit of the oligosaccharyltransferase complex, homolog B; STT3-B; STT3B, catalytic subunit of the oligosaccharyltransferase complex
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12313,036,301 - 13,143,629 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2313,037,722 - 13,143,743 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2313,010,181 - 13,116,925 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02313,327,482 - 13,434,395 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2313,327,493 - 13,434,763 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12313,127,716 - 13,234,421 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02313,271,517 - 13,378,344 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02313,283,996 - 13,390,719 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References
Additional References at PubMed
PMID:12887896   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
STT3B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12313,036,301 - 13,143,629 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2313,037,722 - 13,143,743 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2313,010,181 - 13,116,925 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02313,327,482 - 13,434,395 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2313,327,493 - 13,434,763 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12313,127,716 - 13,234,421 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02313,271,517 - 13,378,344 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02313,283,996 - 13,390,719 (-)NCBIUU_Cfam_GSD_1.0
STT3B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38331,532,925 - 31,637,616 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl331,532,638 - 31,637,616 (+)EnsemblGRCh38hg38GRCh38
GRCh37331,574,417 - 31,679,108 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36331,549,495 - 31,652,560 (+)NCBINCBI36Build 36hg18NCBI36
Celera331,512,441 - 31,615,151 (+)NCBICelera
Cytogenetic Map3p23NCBI
HuRef331,516,641 - 31,619,695 (+)NCBIHuRef
CHM1_1331,524,549 - 31,627,598 (+)NCBICHM1_1
T2T-CHM13v2.0331,535,391 - 31,640,070 (+)NCBIT2T-CHM13v2.0
Stt3b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399115,071,538 - 115,139,536 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9115,071,649 - 115,139,489 (-)EnsemblGRCm39 Ensembl
GRCm389115,242,470 - 115,310,468 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9115,242,581 - 115,310,421 (-)EnsemblGRCm38mm10GRCm38
MGSCv379115,151,699 - 115,219,539 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369115,091,279 - 115,159,119 (-)NCBIMGSCv36mm8
Celera9115,715,885 - 115,785,239 (-)NCBICelera
Cytogenetic Map9F3NCBI
cM Map967.71NCBI
Stt3b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88123,806,836 - 123,872,179 (-)NCBIGRCr8
mRatBN7.28114,928,678 - 114,994,027 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8114,917,824 - 114,994,028 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8120,542,918 - 120,608,216 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08118,741,936 - 118,807,243 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08116,585,033 - 116,650,343 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08123,303,910 - 123,370,729 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8123,293,057 - 123,371,257 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08122,604,518 - 122,668,754 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48119,680,704 - 119,747,784 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18119,690,013 - 119,767,827 (-)NCBI
Celera8114,167,159 - 114,232,088 (-)NCBICelera
Cytogenetic Map8q32NCBI
Stt3b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543022,986,762 - 23,069,383 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543022,986,673 - 23,070,923 (+)NCBIChiLan1.0ChiLan1.0
STT3B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2231,507,762 - 31,616,657 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1331,512,526 - 31,621,423 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0331,454,297 - 31,557,189 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1331,771,271 - 31,873,389 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl331,771,265 - 31,873,381 (+)Ensemblpanpan1.1panPan2
Stt3b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118189,059,062 - 189,150,368 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647322,197,321 - 22,288,941 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647322,197,625 - 22,288,941 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
STT3B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1317,534,171 - 17,635,035 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11317,532,341 - 17,635,039 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21319,678,088 - 19,778,904 (+)NCBISscrofa10.2Sscrofa10.2susScr3
STT3B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11576,060,670 - 76,165,415 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1576,060,406 - 76,165,468 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604149,405,224 - 49,509,806 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Stt3b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247889,615,658 - 9,725,240 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247889,614,932 - 9,726,773 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in STT3B
1155 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 5 22 6 6 6 6 6 12 8 10 6
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000008731   ⟹   ENSCAFP00000008096
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2313,037,722 - 13,143,743 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845039537   ⟹   ENSCAFP00845030985
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2313,327,493 - 13,434,763 (-)Ensembl
RefSeq Acc Id: XM_022408543   ⟹   XP_022264251
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12313,036,301 - 13,135,709 (-)NCBI
Dog10K_Boxer_Tasha2313,010,181 - 13,109,006 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038432078   ⟹   XP_038288006
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02313,327,482 - 13,434,395 (-)NCBI
RefSeq Acc Id: XM_038432079   ⟹   XP_038288007
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02313,327,482 - 13,426,453 (-)NCBI
RefSeq Acc Id: XM_038507384   ⟹   XP_038363312
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12313,127,716 - 13,234,421 (-)NCBI
RefSeq Acc Id: XM_038507385   ⟹   XP_038363313
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12313,127,716 - 13,226,504 (-)NCBI
RefSeq Acc Id: XM_038570618   ⟹   XP_038426546
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02313,283,996 - 13,390,719 (-)NCBI
RefSeq Acc Id: XM_038570619   ⟹   XP_038426547
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02313,283,996 - 13,382,815 (-)NCBI
RefSeq Acc Id: XM_038634808   ⟹   XP_038490736
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02313,271,517 - 13,378,344 (-)NCBI
RefSeq Acc Id: XM_038634809   ⟹   XP_038490737
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02313,273,032 - 13,370,435 (-)NCBI
RefSeq Acc Id: XM_542747   ⟹   XP_542747
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12313,036,301 - 13,143,629 (-)NCBI
Dog10K_Boxer_Tasha2313,010,181 - 13,116,925 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_542747   ⟸   XM_542747
- Peptide Label: isoform X1
- UniProtKB: E2RG47 (UniProtKB/TrEMBL),   A0A8C0R7K4 (UniProtKB/TrEMBL),   A0A8C0LIC6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022264251   ⟸   XM_022408543
- Peptide Label: isoform X2
- UniProtKB: A0A8C0LIC6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000008096   ⟸   ENSCAFT00000008731
RefSeq Acc Id: XP_038363312   ⟸   XM_038507384
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038363313   ⟸   XM_038507385
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038490736   ⟸   XM_038634808
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038490737   ⟸   XM_038634809
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038288006   ⟸   XM_038432078
- Peptide Label: isoform X1
- UniProtKB: E2RG47 (UniProtKB/Swiss-Prot),   A0A8C0R7K4 (UniProtKB/TrEMBL),   A0A8C0LIC6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038288007   ⟸   XM_038432079
- Peptide Label: isoform X2
- UniProtKB: A0A8C0LIC6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038426546   ⟸   XM_038570618
- Peptide Label: isoform X1
- UniProtKB: E2RG47 (UniProtKB/Swiss-Prot),   A0A8C0LIC6 (UniProtKB/TrEMBL),   A0A8C0R7K4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038426547   ⟸   XM_038570619
- Peptide Label: isoform X2
- UniProtKB: A0A8C0LIC6 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845030985   ⟸   ENSCAFT00845039537
Protein Domains
Oligosaccharyl transferase STT3 N-terminal   STT3/PglB/AglB core

Promoters
RGD ID:13687419
Promoter ID:EPDNEW_C5488
Type:initiation region
Name:STT3B_1
Description:Dolichyl-diphosphooligosaccharide--protein glycosyltransferasesubunit STT3B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12313,143,661 - 13,143,721EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000005423 Ensembl, UniProtKB/Swiss-Prot
  ENSCAFG00030017087 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSCAFG00040017680 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSCAFG00805020351 UniProtKB/Swiss-Prot
  ENSCAFG00845022397 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSCAFT00000008731.6 UniProtKB/Swiss-Prot
  ENSCAFT00030031541.1 UniProtKB/TrEMBL
  ENSCAFT00030031681.1 UniProtKB/Swiss-Prot
  ENSCAFT00030031811.1 UniProtKB/TrEMBL
  ENSCAFT00030031909.1 UniProtKB/TrEMBL
  ENSCAFT00030032034.1 UniProtKB/TrEMBL
  ENSCAFT00030032108.1 UniProtKB/TrEMBL
  ENSCAFT00040032882.1 UniProtKB/TrEMBL
  ENSCAFT00040032989.1 UniProtKB/Swiss-Prot
  ENSCAFT00805036801 UniProtKB/Swiss-Prot
  ENSCAFT00845039537 ENTREZGENE
  ENSCAFT00845039537.1 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.12610 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Oligo_trans_STT3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STT3-PglB_core UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STT3_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report cfa:485628 UniProtKB/Swiss-Prot
NCBI Gene STT3B ENTREZGENE
PANTHER DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT STT3B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR13872 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam STT3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STT3-PglB_core UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8C0LIC6 ENTREZGENE
  A0A8C0NJQ6_CANLF UniProtKB/TrEMBL
  A0A8C0NKA6_CANLF UniProtKB/TrEMBL
  A0A8C0NM75_CANLF UniProtKB/TrEMBL
  A0A8C0NS76_CANLF UniProtKB/TrEMBL
  A0A8C0NZF1_CANLF UniProtKB/TrEMBL
  A0A8C0R7K4 ENTREZGENE
  E2RG47 ENTREZGENE, UniProtKB/Swiss-Prot
VGNC ID VGNC:52904 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-01-29 STT3B  STT3 oligosaccharyltransferase complex catalytic subunit B    STT3B, catalytic subunit of the oligosaccharyltransferase complex  Symbol and/or name change 5135510 APPROVED