CD74 (CD74 molecule) - Rat Genome Database

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Gene: CD74 (CD74 molecule) Canis lupus familiaris
Analyze
Symbol: CD74
Name: CD74 molecule
RGD ID: 12116636
Description: ENCODES a protein that exhibits cytokine binding (ortholog); nitric-oxide synthase binding (ortholog); INVOLVED IN antigen processing and presentation (ortholog); antigen processing and presentation of exogenous peptide antigen via MHC class II (ortholog); canonical NF-kappaB signal transduction (ortholog); ASSOCIATED WITH Acute Liver Failure (ortholog); Breast Neoplasms (ortholog); Disease Progression (ortholog); FOUND IN endoplasmic reticulum (ortholog); external side of plasma membrane (ortholog); extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: CD74 molecule, major histocompatibility complex, class II invariant chain; HLA class II histocompatibility antigen gamma chain
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1458,689,745 - 58,698,421 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl458,689,752 - 58,698,151 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha458,456,154 - 58,464,833 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0459,170,613 - 59,179,292 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl459,170,623 - 59,198,795 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1458,959,149 - 58,967,827 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0459,073,563 - 59,082,236 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0459,604,607 - 59,613,287 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
antigen processing and presentation  (IEA,ISO)
antigen processing and presentation of exogenous peptide antigen via MHC class II  (ISO)
canonical NF-kappaB signal transduction  (ISO)
chaperone cofactor-dependent protein refolding  (ISO)
cytokine-mediated signaling pathway  (IEA)
defense response  (ISO)
immune response  (IEA)
immunoglobulin mediated immune response  (ISO)
intracellular protein transport  (IEA,ISO)
macrophage migration inhibitory factor signaling pathway  (ISO)
negative regulation of apoptotic process  (IEA)
negative regulation of cell migration  (IEA)
negative regulation of DNA damage response, signal transduction by p53 class mediator  (IEA)
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator  (IEA)
negative regulation of mature B cell apoptotic process  (ISO)
negative regulation of peptide secretion  (IEA)
negative regulation of T cell differentiation  (ISO)
negative regulation of viral entry into host cell  (ISO)
negative thymic T cell selection  (ISO)
positive regulation of B cell proliferation  (IEA)
positive regulation of canonical NF-kappaB signal transduction  (IEA)
positive regulation of chemokine (C-X-C motif) ligand 2 production  (ISO)
positive regulation of chemokine production  (IEA)
positive regulation of cytokine production involved in inflammatory response  (ISO)
positive regulation of cytokine-mediated signaling pathway  (IEA)
positive regulation of dendritic cell antigen processing and presentation  (ISO)
positive regulation of DNA-templated transcription  (IEA)
positive regulation of ERK1 and ERK2 cascade  (IEA)
positive regulation of fibroblast proliferation  (IEA)
positive regulation of gene expression  (IEA)
positive regulation of inflammatory response  (ISO)
positive regulation of interleukin-6 production  (IEA)
positive regulation of interleukin-8 production  (IEA)
positive regulation of macrophage cytokine production  (IEA)
positive regulation of macrophage migration inhibitory factor signaling pathway  (IEA)
positive regulation of MAPK cascade  (IEA,ISO)
positive regulation of monocyte differentiation  (IEA)
positive regulation of neutrophil chemotaxis  (ISO)
positive regulation of non-canonical NF-kappaB signal transduction  (ISO)
positive regulation of peptidyl-tyrosine phosphorylation  (IEA)
positive regulation of prostaglandin biosynthetic process  (IEA)
positive regulation of protein phosphorylation  (IEA)
positive regulation of T cell differentiation  (ISO)
positive regulation of type 2 immune response  (IEA)
positive regulation of viral entry into host cell  (IEA)
positive thymic T cell selection  (ISO)
prostaglandin biosynthetic process  (IEA)
protein folding  (IEA)
protein stabilization  (ISO)
protein trimerization  (IEA)
protein-containing complex assembly  (ISO)
response to type II interferon  (IEA)
signal transduction involved in regulation of gene expression  (ISO)
T cell activation involved in immune response  (IEA)

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CD74
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1458,689,745 - 58,698,421 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl458,689,752 - 58,698,151 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha458,456,154 - 58,464,833 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0459,170,613 - 59,179,292 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl459,170,623 - 59,198,795 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1458,959,149 - 58,967,827 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0459,073,563 - 59,082,236 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0459,604,607 - 59,613,287 (+)NCBIUU_Cfam_GSD_1.0
CD74
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385150,401,639 - 150,412,910 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5150,401,637 - 150,412,969 (-)EnsemblGRCh38hg38GRCh38
GRCh375149,781,202 - 149,792,473 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365149,761,393 - 149,772,525 (-)NCBINCBI36Build 36hg18NCBI36
Build 345149,761,396 - 149,772,511NCBI
Celera5145,862,277 - 145,873,409 (-)NCBICelera
Cytogenetic Map5q33.1NCBI
HuRef5144,928,781 - 144,940,080 (-)NCBIHuRef
CHM1_15149,213,619 - 149,224,915 (-)NCBICHM1_1
T2T-CHM13v2.05150,938,180 - 150,949,451 (-)NCBIT2T-CHM13v2.0
Cd74
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391860,936,921 - 60,945,724 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1860,936,920 - 60,945,724 (+)EnsemblGRCm39 Ensembl
GRCm381860,803,849 - 60,812,652 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1860,803,848 - 60,812,652 (+)EnsemblGRCm38mm10GRCm38
MGSCv371860,963,503 - 60,972,306 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361860,929,247 - 60,938,021 (+)NCBIMGSCv36mm8
Celera1862,088,874 - 62,098,436 (+)NCBICelera
Cytogenetic Map18E1NCBI
cM Map1834.41NCBI
Cd74
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81856,527,071 - 56,536,406 (+)NCBIGRCr8
mRatBN7.21854,256,757 - 54,266,003 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1854,256,778 - 54,266,003 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1856,345,511 - 56,354,694 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01857,060,123 - 57,069,310 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01854,880,697 - 54,889,895 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01856,071,420 - 56,080,851 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1856,071,478 - 56,080,849 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01855,305,827 - 55,315,246 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41856,756,511 - 56,765,711 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11856,828,786 - 56,837,940 (+)NCBI
Celera1852,411,586 - 52,420,786 (+)NCBICelera
RH 3.4 Map18525.0RGD
Cytogenetic Map18q12.1NCBI
Cd74
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554154,129,254 - 4,137,826 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554154,129,151 - 4,138,336 (+)NCBIChiLan1.0ChiLan1.0
CD74
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24145,629,969 - 145,641,243 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15143,769,515 - 143,780,789 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05145,825,635 - 145,836,916 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15151,830,311 - 151,841,334 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5151,830,311 - 151,841,334 (-)Ensemblpanpan1.1panPan2
Cd74
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213142,948,591 - 142,958,314 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365044,522,751 - 4,531,750 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365044,522,576 - 4,532,289 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CD74
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2151,402,211 - 151,409,833 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12151,402,210 - 151,409,924 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
CD74
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12353,008,802 - 53,022,953 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2353,009,394 - 53,022,923 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603424,695,767 - 24,707,325 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cd74
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247749,700,393 - 9,709,514 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247749,699,876 - 9,708,871 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CD74
110 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High 6 5
Medium 5 5 22 6 6 6 2 12 5 6
Low 4 8
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005619298 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038473947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038473948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038473949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038473950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038497664 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038497678 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038535039 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038535040 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038535041 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038535042 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038599336 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038599337 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038599338 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038599339 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038663647 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038663648 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038663649 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038663650 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_536468 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000088 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000355 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000028776   ⟹   ENSCAFP00000026761
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl458,689,934 - 58,697,904 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000076946   ⟹   ENSCAFP00000045678
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl458,689,752 - 58,698,151 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000085581   ⟹   ENSCAFP00000056283
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl458,689,752 - 58,696,726 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845012204   ⟹   ENSCAFP00845009540
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl459,170,623 - 59,178,345 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845012264   ⟹   ENSCAFP00845009588
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl459,170,714 - 59,179,288 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845012331   ⟹   ENSCAFP00845009638
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl459,170,765 - 59,198,795 (+)Ensembl
RefSeq Acc Id: XM_005619298   ⟹   XP_005619355
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1458,689,751 - 58,698,421 (+)NCBI
Dog10K_Boxer_Tasha458,456,162 - 58,464,833 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038473947   ⟹   XP_038329875
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1458,959,150 - 58,967,827 (+)NCBI
RefSeq Acc Id: XM_038473948   ⟹   XP_038329876
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1458,959,149 - 58,967,827 (+)NCBI
RefSeq Acc Id: XM_038473949   ⟹   XP_038329877
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1458,959,157 - 58,967,827 (+)NCBI
RefSeq Acc Id: XM_038473950   ⟹   XP_038329878
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1458,959,155 - 58,967,827 (+)NCBI
RefSeq Acc Id: XM_038497664   ⟹   XP_038353592
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha458,456,154 - 58,464,833 (+)NCBI
RefSeq Acc Id: XM_038497678   ⟹   XP_038353606
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha458,456,160 - 58,464,833 (+)NCBI
RefSeq Acc Id: XM_038535039   ⟹   XP_038390967
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0459,604,608 - 59,613,287 (+)NCBI
RefSeq Acc Id: XM_038535040   ⟹   XP_038390968
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0459,604,607 - 59,613,287 (+)NCBI
RefSeq Acc Id: XM_038535041   ⟹   XP_038390969
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0459,604,615 - 59,613,287 (+)NCBI
RefSeq Acc Id: XM_038535042   ⟹   XP_038390970
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0459,604,613 - 59,613,287 (+)NCBI
RefSeq Acc Id: XM_038599336   ⟹   XP_038455264
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0459,073,564 - 59,082,236 (+)NCBI
RefSeq Acc Id: XM_038599337   ⟹   XP_038455265
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0459,073,563 - 59,082,236 (+)NCBI
RefSeq Acc Id: XM_038599338   ⟹   XP_038455266
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0459,073,571 - 59,082,236 (+)NCBI
RefSeq Acc Id: XM_038599339   ⟹   XP_038455267
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0459,073,568 - 59,082,236 (+)NCBI
RefSeq Acc Id: XM_038663647   ⟹   XP_038519575
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0459,170,614 - 59,179,292 (+)NCBI
RefSeq Acc Id: XM_038663648   ⟹   XP_038519576
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0459,170,613 - 59,179,292 (+)NCBI
RefSeq Acc Id: XM_038663649   ⟹   XP_038519577
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0459,170,621 - 59,179,292 (+)NCBI
RefSeq Acc Id: XM_038663650   ⟹   XP_038519578
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0459,170,619 - 59,179,292 (+)NCBI
RefSeq Acc Id: XM_536468   ⟹   XP_536468
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1458,689,745 - 58,698,421 (+)NCBI
Dog10K_Boxer_Tasha458,456,155 - 58,464,833 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_536468   ⟸   XM_536468
- Peptide Label: isoform X1
- UniProtKB: A0A8C0S1D1 (UniProtKB/TrEMBL),   A0A8C0LI20 (UniProtKB/TrEMBL),   A0A8I3N490 (UniProtKB/TrEMBL),   A0A8C0LIF5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005619355   ⟸   XM_005619298
- Peptide Label: isoform X2
- UniProtKB: A0A8C0LGA4 (UniProtKB/TrEMBL),   A0A8I3RTM7 (UniProtKB/TrEMBL),   A0A8P0NJF5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000026761   ⟸   ENSCAFT00000028776
RefSeq Acc Id: ENSCAFP00000045678   ⟸   ENSCAFT00000076946
RefSeq Acc Id: ENSCAFP00000056283   ⟸   ENSCAFT00000085581
RefSeq Acc Id: XP_038329876   ⟸   XM_038473948
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038329875   ⟸   XM_038473947
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038329878   ⟸   XM_038473950
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038329877   ⟸   XM_038473949
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038455265   ⟸   XM_038599337
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038455264   ⟸   XM_038599336
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038455267   ⟸   XM_038599339
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038455266   ⟸   XM_038599338
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038519576   ⟸   XM_038663648
- Peptide Label: isoform X1
- UniProtKB: A0A8C0S1D1 (UniProtKB/TrEMBL),   A0A8C0LI20 (UniProtKB/TrEMBL),   A0A8I3N490 (UniProtKB/TrEMBL),   A0A8C0LIF5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038519575   ⟸   XM_038663647
- Peptide Label: isoform X1
- UniProtKB: A0A8C0S1D1 (UniProtKB/TrEMBL),   A0A8C0LI20 (UniProtKB/TrEMBL),   A0A8I3N490 (UniProtKB/TrEMBL),   A0A8C0LIF5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038519578   ⟸   XM_038663650
- Peptide Label: isoform X2
- UniProtKB: A0A8C0LGA4 (UniProtKB/TrEMBL),   A0A8I3RTM7 (UniProtKB/TrEMBL),   A0A8P0NJF5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038519577   ⟸   XM_038663649
- Peptide Label: isoform X2
- UniProtKB: A0A8C0LGA4 (UniProtKB/TrEMBL),   A0A8I3RTM7 (UniProtKB/TrEMBL),   A0A8P0NJF5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038353592   ⟸   XM_038497664
- Peptide Label: isoform X1
- UniProtKB: A0A8C0S1D1 (UniProtKB/TrEMBL),   A0A8C0LI20 (UniProtKB/TrEMBL),   A0A8I3N490 (UniProtKB/TrEMBL),   A0A8C0LIF5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038353606   ⟸   XM_038497678
- Peptide Label: isoform X2
- UniProtKB: A0A8C0LGA4 (UniProtKB/TrEMBL),   A0A8I3RTM7 (UniProtKB/TrEMBL),   A0A8P0NJF5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038390968   ⟸   XM_038535040
- Peptide Label: isoform X1
- UniProtKB: A0A8C0LI20 (UniProtKB/TrEMBL),   A0A8C0LIF5 (UniProtKB/TrEMBL),   A0A8C0S1D1 (UniProtKB/TrEMBL),   A0A8I3N490 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038390967   ⟸   XM_038535039
- Peptide Label: isoform X1
- UniProtKB: A0A8C0LI20 (UniProtKB/TrEMBL),   A0A8C0LIF5 (UniProtKB/TrEMBL),   A0A8C0S1D1 (UniProtKB/TrEMBL),   A0A8I3N490 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038390970   ⟸   XM_038535042
- Peptide Label: isoform X2
- UniProtKB: A0A8C0LGA4 (UniProtKB/TrEMBL),   A0A8I3RTM7 (UniProtKB/TrEMBL),   A0A8P0NJF5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038390969   ⟸   XM_038535041
- Peptide Label: isoform X2
- UniProtKB: A0A8C0LGA4 (UniProtKB/TrEMBL),   A0A8I3RTM7 (UniProtKB/TrEMBL),   A0A8P0NJF5 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845009638   ⟸   ENSCAFT00845012331
RefSeq Acc Id: ENSCAFP00845009540   ⟸   ENSCAFT00845012204
RefSeq Acc Id: ENSCAFP00845009588   ⟸   ENSCAFT00845012264
Protein Domains
MHC class II-associated invariant chain   MHC class II-associated invariant chain/CLIP MHC II-   Thyroglobulin type-1

Promoters
RGD ID:13683028
Promoter ID:EPDNEW_C1093
Type:multiple initiation site
Name:CD74_1
Description:CD74 molecule
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1458,689,894 - 58,689,954EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000018101 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030002877 UniProtKB/TrEMBL
  ENSCAFG00040008960 UniProtKB/TrEMBL
  ENSCAFG00845006874 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000028776.5 UniProtKB/TrEMBL
  ENSCAFT00000076946.2 UniProtKB/TrEMBL
  ENSCAFT00000085581.2 UniProtKB/TrEMBL
  ENSCAFT00030005346.1 UniProtKB/TrEMBL
  ENSCAFT00040016630.1 UniProtKB/TrEMBL
  ENSCAFT00040016719.1 UniProtKB/TrEMBL
  ENSCAFT00845012204.1 UniProtKB/TrEMBL
  ENSCAFT00845012264 ENTREZGENE
  ENSCAFT00845012264.1 UniProtKB/TrEMBL
  ENSCAFT00845012331 ENTREZGENE
  ENSCAFT00845012331.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.870.10 UniProtKB/TrEMBL
  4.10.800.10 UniProtKB/TrEMBL
InterPro CD74_antigen UniProtKB/TrEMBL
  MHC_II-assoc_invar/CLIP_MHC-bd UniProtKB/TrEMBL
  MHC_II-assoc_invar_chain UniProtKB/TrEMBL
  MHC_II-assoc_invariant_trimer UniProtKB/TrEMBL
  MHCII_invariant_trimer_sf UniProtKB/TrEMBL
  Thyroglobulin_1 UniProtKB/TrEMBL
  Thyroglobulin_1_sf UniProtKB/TrEMBL
KEGG Report cfa:479329 UniProtKB/TrEMBL
NCBI Gene CD74 ENTREZGENE
PANTHER HLA CLASS II GAMMA CHAIN UniProtKB/TrEMBL
  HLA CLASS II HISTOCOMPATIBILITY ANTIGEN GAMMA CHAIN UniProtKB/TrEMBL
Pfam MHC2-interact UniProtKB/TrEMBL
  MHCassoc_trimer UniProtKB/TrEMBL
  Thyroglobulin_1 UniProtKB/TrEMBL
PIRSF CD74_antigen UniProtKB/TrEMBL
PRINTS CD74ANTIGEN UniProtKB/TrEMBL
PROSITE THYROGLOBULIN_1_1 UniProtKB/TrEMBL
  THYROGLOBULIN_1_2 UniProtKB/TrEMBL
SMART SM00211 UniProtKB/TrEMBL
Superfamily-SCOP SSF48305 UniProtKB/TrEMBL
  SSF57610 UniProtKB/TrEMBL
UniProt A0A8C0LGA4 ENTREZGENE
  A0A8C0LI20 ENTREZGENE
  A0A8C0LIF5 ENTREZGENE
  A0A8C0S1D1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0S1K8_CANLF UniProtKB/TrEMBL
  A0A8I3N448_CANLF UniProtKB/TrEMBL
  A0A8I3N490 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3RTM7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0NJF5 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A8P0P5P0 UniProtKB/TrEMBL
VGNC ID VGNC:38972 ENTREZGENE