LOC100990437 (NADPH--cytochrome P450 reductase)

Gene: LOC100990437 (NADPH--cytochrome P450 reductase) Pan paniscus

Analyze

Symbol:

LOC100990437 (Ensembl: POR)

Name:

NADPH--cytochrome P450 reductase (Ensembl:cytochrome p450 oxidoreductase)

RGD ID:

11805686

Description:

ENCODES a protein that exhibits cytochrome-b5 reductase activity, acting on NAD(P)H (ortholog); electron transfer activity (ortholog); enzyme binding (ortholog); INVOLVED IN carnitine metabolic process (ortholog); cellular response to follicle-stimulating hormone stimulus (ortholog); cellular response to gonadotropin stimulus (ortholog); PARTICIPATES IN aldosterone biosynthetic pathway; cortisol biosynthetic pathway; doxorubicin pharmacokinetics pathway; ASSOCIATED WITH 46, XY Disorders of Sex Development (ortholog); amenorrhea (ortholog); Antley-Bixler syndrome (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); endoplasmic reticulum (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

P450 (cytochrome) oxidoreductase; POR

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	6	93,968,924 - 94,040,322 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	7	142,233,562 - 142,304,506 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	7	68,035,021 - 68,105,934 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	7	82,364,311 - 82,437,530 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	7	82,364,418 - 82,437,530 (+)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

46, XY Disorders of Sex Development (ISO)

amenorrhea (ISO)

Antley-Bixler syndrome (ISO)

Antley-Bixler syndrome with disordered steroidogenesis (ISO)

Antley-Bixler syndrome without disordered steroidogenesis (ISO)

Chromosome 7q11.23 Deletion Syndrome, Distal, 1.2-MB (ISO)

congenital adrenal hyperplasia (ISO)

Congenital Adrenal Hyperplasia due to 21 Hydroxylase Deficiency (ISO)

congestive heart failure (ISO)

cytochrome P450 oxidoreductase deficiency (ISO)

disorder of sexual development (ISO)

Fine-Lubinsky Syndrome (ISO)

genetic disease (ISO)

gliosarcoma (ISO)

Hirschsprung's disease (ISO)

Hypotension (ISO)

learning disability (ISO)

Lung Injury (ISO)

Musculoskeletal Abnormalities (ISO)

Neoplastic Cell Transformation (ISO)

neural tube defect (ISO)

pleomorphic xanthoastrocytoma (ISO)

primary ovarian insufficiency (ISO)

urinary bladder cancer (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

carnitine metabolic process (ISO)

cellular organofluorine metabolic process (IEA)

cellular response to follicle-stimulating hormone stimulus (ISO)

cellular response to gonadotropin stimulus (ISO)

cellular response to peptide hormone stimulus (ISO)

demethylation (ISO)

electron transport chain (IEA)

fatty acid oxidation (ISO)

flavonoid metabolic process (ISO)

internal peptidyl-lysine acetylation (ISO)

negative regulation of apoptotic process (ISO)

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process (ISO)

negative regulation of lipase activity (ISO)

nitrate catabolic process (ISO)

nitric oxide catabolic process (ISO)

positive regulation of cholesterol biosynthetic process (ISO)

positive regulation of chondrocyte differentiation (ISO)

positive regulation of smoothened signaling pathway (ISO)

positive regulation of steroid hormone biosynthetic process (ISO)

regulation of cholesterol metabolic process (ISO)

regulation of growth plate cartilage chondrocyte proliferation (ISO)

response to dexamethasone (ISO)

response to hormone (IEA)

response to nutrient (ISO)

response to xenobiotic stimulus (ISO)

Cellular Component

cytoplasm (IEA)

cytosol (IEA)

endoplasmic reticulum (IEA)

endoplasmic reticulum membrane (IEA)

intracellular membrane-bounded organelle (IEA)

membrane (IEA)

Molecular Function

cytochrome-b5 reductase activity, acting on NAD(P)H (ISO)

electron transfer activity (ISO)

enzyme binding (ISO)

flavin adenine dinucleotide binding (IEA,ISO)

FMN binding (IEA,ISO)

hydrolase activity (ISO)

iron-cytochrome-c reductase activity (ISO)

NADP binding (IEA,ISO)

NADPH-hemoprotein reductase activity (IEA,ISO)

nitric oxide dioxygenase NAD(P)H activity (ISO)

oxidoreductase activity (IEA)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

aldosterone biosynthetic pathway (ISO)

cortisol biosynthetic pathway (ISO)

doxorubicin pharmacokinetics pathway (ISO)

estradiol biosynthetic pathway (ISO)

steroid hormone biosynthetic pathway (ISO)

testosterone biosynthetic pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

LOC100990437
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	6	93,968,924 - 94,040,322 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	7	142,233,562 - 142,304,506 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	7	68,035,021 - 68,105,934 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	7	82,364,311 - 82,437,530 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	7	82,364,418 - 82,437,530 (+)	Ensembl	panpan1.1		panPan2

POR
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	7	75,915,155 - 75,986,855 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	7	75,899,200 - 75,986,855 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	7	75,544,473 - 75,616,173 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	75,382,356 - 75,454,109 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	7	75,227,957 - 75,260,823	NCBI
Celera	7	70,412,991 - 70,484,717 (+)	NCBI		Celera
Cytogenetic Map	7	q11.23	NCBI
HuRef	7	70,631,215 - 70,702,985 (+)	NCBI		HuRef
CHM1_1	7	75,474,511 - 75,546,243 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	7	77,202,773 - 77,274,511 (+)	NCBI		T2T-CHM13v2.0
CRA_TCAGchr7v2	7	74,877,484 - 74,949,237 (+)	NCBI

Por
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	135,698,894 - 135,764,180 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	135,698,887 - 135,764,180 (+)	Ensembl		GRCm39 Ensembl
GRCm38	5	135,670,040 - 135,735,326 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	135,670,033 - 135,735,326 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	5	136,165,084 - 136,211,195 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	5	135,973,841 - 136,019,952 (+)	NCBI		MGSCv36	mm8
Celera	5	132,696,393 - 132,742,504 (+)	NCBI		Celera
Cytogenetic Map	5	G2	NCBI
cM Map	5	75.34	NCBI

Por
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	26,587,674 - 26,655,612 (-)	NCBI		GRCr8
mRatBN7.2	12	20,951,058 - 20,999,198 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	20,951,058 - 20,999,245 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	12	22,092,790 - 22,140,733 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	22,705,228 - 22,753,069 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	21,771,683 - 21,819,534 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	23,998,411 - 24,017,063 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	23,998,411 - 24,046,814 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	12	25,995,663 - 26,014,366 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	12	22,078,629 - 22,097,301 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	12	22,065,892 - 22,141,603 (-)	NCBI
Celera	12	22,713,689 - 22,732,174 (-)	NCBI		Celera
Cytogenetic Map	12	q12	NCBI

Por
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955456	14,698,589 - 14,748,520 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955456	14,698,589 - 14,748,520 (+)	NCBI	ChiLan1.0	ChiLan1.0

POR
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	7,247,780 - 7,316,282 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	7,263,574 - 7,316,297 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	8,984,488 - 9,012,689 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	7,068,561 - 7,137,106 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	7,074,449 - 7,192,344 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	7,077,907 - 7,106,119 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	7,041,376 - 7,069,585 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	7,204,608 - 7,232,825 (+)	NCBI		UU_Cfam_GSD_1.0

LOC101965545
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	131,708,573 - 131,760,586 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936543	2,274,059 - 2,328,008 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936543	2,275,981 - 2,327,931 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

POR
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	10,212,735 - 10,281,823 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	10,212,734 - 10,272,184 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

LOC103246654
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	28	10,145,070 - 10,230,836 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	28	10,197,503 - 10,230,468 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666070	6,191,559 - 6,265,374 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

LOC101712555
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624740	14,733,427 - 14,791,065 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624740	14,739,458 - 14,790,736 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003808918	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008961065	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008961066	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_014345705	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034965382	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034965383	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_057302889	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063605922	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063605923	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSPPAT00000052303 ⟹ ENSPPAP00000029454

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	7	82,364,418 - 82,437,530 (+)	Ensembl

RefSeq Acc Id:

ENSPPAT00000052309 ⟹ ENSPPAP00000029460

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	7	82,405,048 - 82,437,152 (+)	Ensembl

RefSeq Acc Id:

XM_003808918 ⟹ XP_003808966

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	6	93,968,924 - 94,040,322 (-)	NCBI
NHGRI_mPanPan1	7	142,233,562 - 142,304,506 (-)	NCBI
Mhudiblu_PPA_v0	7	68,035,021 - 68,105,934 (-)	NCBI
PanPan1.1	7	82,364,311 - 82,437,530 (+)	NCBI

Sequence:

show sequence

CCACCCCCGCGGCCGGCGAAGGCGGTGGTAGCGCCTCAGTGGTGCGGGCCTGCGCCCTGCCCAG
GTGCCCGCAGAGAGCAGCCGGGCTGCCAGCGTTTCATGATCAACATGGGGGACTCCCACGTGGA
CACCAGCTCCACTGTGTCCGAGGCGGTGGCCGAAGAAGTATCTCTTTTCAGCATGACGGACATG
ATTCTGTTTTCGCTCATCGTGGGTCTCCTAACCTACTGGTTCCTCTTCAGAAAGAAAAAAGAAG
AAGTCCCCGAGTTCACCAAAATTCAGACATTGACCTCCTCTGTCAGAGAGAGCAGCTTTGTGGA
AAAGATGAAGAAAACGGGGAGGAACATCATCGTGTTCTACGGCTCCCAGACGGGGACTGCAGAG
GAGTTTGCCAACCGCCTGTCCAAGGACGCCCACCGCTACGGGATGCGAGGCATGTCAGCGGACC
CTGAGGAGTATGACCTGGCCGACCTGAGCAGCCTGCCAGAGATCGACAACGCCCTGGTGGTTTT
CTGCATGGCCACCTACGGTGAGGGAGACCCCACCGACAATGCCCAGGACTTCTACGACTGGCTG
CAGGAGACAGACGTGGATCTCTCTGGGGTCAAGTTCGCGGTGTTTGGTCTTGGGAACAAGACCT
ACGAGCACTTCAATGCCATGGGCAAGTACGTGGACAAGCGGCTGGAGCAGCTCGGCGCCCAGCG
CATCTTTGAGCTGGGGTTGGGCGACGACGATGGGAACTTGGAGGAGGACTTCATCACCTGGCGA
GAGCAGTTCTGGCCGGCCGTGTGTGAACACTTTGGGGTGGAAGCCACTGGCGAGGAGTCCAGCA
TTCGCCAGTACGAGCTTGTGGTCCACACCGACATAGACGCGGCCAAGGTGTACATGGGGGAGAT
GGGCCGGCTGAAGAGCTACGAGAACCAGAAGCCCCCCTTTGATGCCAAGAATCCGTTCCTGGCT
GCAGTCACCACCAACCGGAAGCTGAACCAGGGAACCGAGCGCCACCTCATGCACCTGGAATTGG
ACATCTCAGACTCCAAAATCAGGTATGAATCTGGGGACCACGTGGCTGTGTACCCAGCCAACGA
CTCTGCTCTCGTCAACCAGCTGGGCAAAATCCTGGGTGCCGACCTGGACATTGTCATGTCCCTG
AACAACCTGGATGAGGAGTCCAACAAGAAGCACCCATTCCCGTGCCCTACGTCCTACCGCACGG
CCCTCACCTACTACCTGGACATCACCAACCCGCCGCGCACCAACGTGCTGTACGAGCTGGCGCA
GTACGCCTCGGAGCCCTCGGAGCAGGAGCTGCTGCGCAAGATGGCCTCCTCCTCCGGCGAGGGC
AAGGAGCTGTACCTGAGCTGGGTGGTGGAGGCCCGGAGGCACATCCTGGCCATCCTGCAGGACT
GCCCGTCCCTGCGGCCCCCCATCGACCACCTGTGTGAGCTGCTGCCGCGCCTGCAGGCCCGCTA
CTACTCTATCGCCTCATCCTCCAAGGTCCACCCCAACTCTGTGCACATCTGTGCGGTGGTTGTG
GAGTACGAGACCAAGGCCGGCCGCATCAACAAGGGCGTGGCCACCAACTGGCTGCGGGCCAAGG
AGCCTGCCGGGGAGAACGGCGGCCGTGCACTGGTGCCCATGTTCGTGCGCAAGTCCCAGTTCCG
CCTGCCCTTCAAGGCCACCACGCCTGTCATCATGGTGGGCCCCGGCACCGGGGTGGCACCCTTC
ATAGGCTTCATCCAGGAGCGGGCCTGGCTGCGACAGCAGGGAAAGGAGGTGGGGGAGACGCTGT
TGTACTACGGCTGCCGCCGCTCGGATGAGGACTACCTGTACCGGGAGGAGCTGGCGCAGTTCCA
CAGGGACGGTGCGCTCACCCAGCTCAACGTGGCCTTCTCCCGGGAGCAGTCCCACAAGGTCTAC
GTCCAGCACCTGCTAAAGCGAGACCGAGAGCACCTGTGGAAGTTGATCGAAGGCGGTGCCCACA
TCTACGTCTGTGGGGATGCACGGAACATGGCCAGGGATGTGCAGAACACCTTCTACGACATCGT
GGCTGAGCTCGGGGCCATGGAGCACGCACAGGCGGTGGACTACATCAAGAAACTGATGACCAAG
GGCCGCTACTCCCTGGACGTGTGGAGCTAGGGGCCTGCCTGCCTGCCCCACCCACCCCACAGAC
TCCGGCCTGTAATCAGCTCTCCTGGCTCCCTCCCGTAGTCTCCTGGGTGTGTTTGGCTTGGCCT
TGGCATGGGCGCAGGCCCAGTGACAAAGACTCCTCCGGGCCTGGGGTGCATCCTCCTCAGCCCC
CAGGCCAGGTGAGGTCCACTGGCCCCTGGCAGCACAGCCCAGGGCCTGCACGGGGGCACCGGGC
TCCATGCCTCTGGAGGCCTCTGGCCCTCGGTGGCTGCACAGAAGGGCTCTTTCTCTCTGCTGAG
CTGGGCCCAGCCCCTCCACGTGATTTCCAGTGAGTGTAAATAATTTTAAATAACCTCTGGCCCT
TGGAATAAAGTTCTGTTTTCTGTA

hide sequence

RefSeq Acc Id:

XM_057302889 ⟹ XP_057158872

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	6	93,968,924 - 94,001,619 (-)	NCBI
NHGRI_mPanPan1	7	142,233,562 - 142,249,187 (-)	NCBI

RefSeq Acc Id:

XM_063605922 ⟹ XP_063461992

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	6	93,968,924 - 94,032,814 (-)	NCBI

RefSeq Acc Id:

XM_063605923 ⟹ XP_063461993

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	6	93,968,924 - 93,984,612 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_003808966	(Get FASTA)	NCBI Sequence Viewer
	XP_057158872	(Get FASTA)	NCBI Sequence Viewer
	XP_063461992	(Get FASTA)	NCBI Sequence Viewer
	XP_063461993	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000029454.1
	ENSPPAP00000029460.1

RefSeq Acc Id:	XP_003808966 ⟸ XM_003808918
- Peptide Label:	isoform X1
- UniProtKB:	A0A2R9BIH1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MINMGDSHVDTSSTVSEAVAEEVSLFSMTDMILFSLIVGLLTYWFLFRKKKEEVPEFTKIQTLT SSVRESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSL PEIDNALVVFCMATYGEGDPTDNAQDFYDWLQETDVDLSGVKFAVFGLGNKTYEHFNAMGKYVD KRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEHFGVEATGEESSIRQYELVVHTDI DAAKVYMGEMGRLKSYENQKPPFDAKNPFLAAVTTNRKLNQGTERHLMHLELDISDSKIRYESG DHVAVYPANDSALVNQLGKILGADLDIVMSLNNLDEESNKKHPFPCPTSYRTALTYYLDITNPP RTNVLYELAQYASEPSEQELLRKMASSSGEGKELYLSWVVEARRHILAILQDCPSLRPPIDHLC ELLPRLQARYYSIASSSKVHPNSVHICAVVVEYETKAGRINKGVATNWLRAKEPAGENGGRALV PMFVRKSQFRLPFKATTPVIMVGPGTGVAPFIGFIQERAWLRQQGKEVGETLLYYGCRRSDEDY LYREELAQFHRDGALTQLNVAFSREQSHKVYVQHLLKRDREHLWKLIEGGAHIYVCGDARNMAR DVQNTFYDIVAELGAMEHAQAVDYIKKLMTKGRYSLDVWS hide sequence

RefSeq Acc Id:

ENSPPAP00000029454 ⟸ ENSPPAT00000052303

RefSeq Acc Id:

ENSPPAP00000029460 ⟸ ENSPPAT00000052309

RefSeq Acc Id:	XP_057158872 ⟸ XM_057302889
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_063461992 ⟸ XM_063605922
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_063461993 ⟸ XM_063605923
- Peptide Label:	isoform X3

Protein Domains

FAD-binding FR-type Flavodoxin-like

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000037718	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000052303.1	UniProtKB/TrEMBL
	ENSPPAT00000052309.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.360	UniProtKB/TrEMBL
	3.40.50.80	UniProtKB/TrEMBL
	Translation factors	UniProtKB/TrEMBL
InterPro	CysJ-like_FAD-binding	UniProtKB/TrEMBL
	FAD-bd_FR_type	UniProtKB/TrEMBL
	Flavdoxin-like	UniProtKB/TrEMBL
	Flavodoxin/NO_synth	UniProtKB/TrEMBL
	Flavoprot_Pyr_Nucl_cyt_Rdtase	UniProtKB/TrEMBL
	Flavoprotein-like_sf	UniProtKB/TrEMBL
	FNR_nucleotide-bd	UniProtKB/TrEMBL
	NADPH_Cyt_P450_Rdtase_alpha	UniProtKB/TrEMBL
	OxRdtase_FAD/NAD-bd	UniProtKB/TrEMBL
	P450R	UniProtKB/TrEMBL
	Riboflavin_synthase-like_b-brl	UniProtKB/TrEMBL
KEGG Report	pps:100990437	UniProtKB/TrEMBL
NCBI Gene	POR	ENTREZGENE
PANTHER	NADPH--CYTOCHROME P450 REDUCTASE	UniProtKB/TrEMBL
	NITRIC OXIDE SYNTHASE-RELATED	UniProtKB/TrEMBL
Pfam	FAD_binding_1	UniProtKB/TrEMBL
	Flavodoxin_1	UniProtKB/TrEMBL
	NAD_binding_1	UniProtKB/TrEMBL
PIRSF	P450R	UniProtKB/TrEMBL
PRINTS	FLAVODOXIN	UniProtKB/TrEMBL
	FPNCR	UniProtKB/TrEMBL
PROSITE	FAD_FR	UniProtKB/TrEMBL
	FLAVODOXIN_LIKE	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52218	UniProtKB/TrEMBL
	SSF52343	UniProtKB/TrEMBL
	SSF63380	UniProtKB/TrEMBL
UniProt	A0A2R9BIH0_PANPA	UniProtKB/TrEMBL
	A0A2R9BIH1	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2018-05-08	LOC100990437	NADPH--cytochrome P450 reductase	POR	P450 (cytochrome) oxidoreductase	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB