TSLP (thymic stromal lymphopoietin) - Rat Genome Database

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Pathways
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Gene: TSLP (thymic stromal lymphopoietin) Pan paniscus
Analyze
Symbol: TSLP
Name: thymic stromal lymphopoietin
RGD ID: 11803615
Description: ENCODES a protein that exhibits cytokine activity (inferred); interleukin-7 receptor binding (inferred); INVOLVED IN cell surface receptor signaling pathway via JAK-STAT (ortholog); defense response to fungus (ortholog); defense response to Gram-negative bacterium (ortholog); ASSOCIATED WITH Albuminuria (ortholog); allergic contact dermatitis (ortholog); asthma (ortholog); FOUND IN extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24106,340,561 - 106,348,525 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15104,494,184 - 104,502,180 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05106,440,136 - 106,446,849 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15112,242,490 - 112,249,200 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5112,242,490 - 112,250,130 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
TSLP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24106,340,561 - 106,348,525 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15104,494,184 - 104,502,180 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05106,440,136 - 106,446,849 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15112,242,490 - 112,249,200 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5112,242,490 - 112,250,130 (+)Ensemblpanpan1.1panPan2
TSLP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385111,070,062 - 111,078,026 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5111,070,062 - 111,078,026 (+)EnsemblGRCh38hg38GRCh38
GRCh375110,405,760 - 110,413,724 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365110,435,289 - 110,441,623 (+)NCBINCBI36Build 36hg18NCBI36
Celera5106,353,329 - 106,359,661 (+)NCBICelera
Cytogenetic Map5q22.1NCBI
HuRef5105,584,896 - 105,592,841 (+)NCBIHuRef
CHM1_15109,839,103 - 109,847,047 (+)NCBICHM1_1
T2T-CHM13v2.05111,580,695 - 111,588,660 (+)NCBIT2T-CHM13v2.0
Tslp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391832,948,436 - 32,952,852 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1832,948,436 - 32,952,850 (+)EnsemblGRCm39 Ensembl
GRCm381832,815,383 - 32,819,799 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1832,815,383 - 32,819,797 (+)EnsemblGRCm38mm10GRCm38
MGSCv371832,975,037 - 32,979,453 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361832,958,393 - 32,962,802 (+)NCBIMGSCv36mm8
Celera1833,286,509 - 33,290,920 (+)NCBICelera
Cytogenetic Map18B1NCBI
cM Map1818.12NCBI
Tslp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81824,723,990 - 24,728,419 (+)NCBIGRCr8
mRatBN7.21824,447,409 - 24,454,244 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1824,449,844 - 24,453,548 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01825,613,601 - 25,618,066 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1825,613,831 - 25,617,361 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01825,326,396 - 25,333,230 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41825,268,082 - 25,274,214 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1824,198,059 - 24,202,524 (+)NCBICelera
Cytogenetic Map18p12NCBI
Tslp
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554184,041,529 - 4,045,534 (-)NCBIChiLan1.0ChiLan1.0
TSLP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.131,502,469 - 1,507,696 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl31,503,188 - 1,507,696 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha32,907,296 - 2,971,755 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.031,393,149 - 1,400,425 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.131,339,901 - 1,404,345 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.031,341,683 - 1,348,998 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.031,506,469 - 1,571,642 (-)NCBIUU_Cfam_GSD_1.0
Tslp
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213156,110,394 - 156,115,633 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365315,495,872 - 5,500,462 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TSLP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.12115,832,152 - 115,837,572 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22120,289,894 - 120,323,977 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TSLP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12314,419,820 - 14,423,331 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603464,056,775 - 64,060,255 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000051785   ⟹   ENSPPAP00000028937
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl5112,242,490 - 112,249,200 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000051787   ⟹   ENSPPAP00000028939
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl5112,244,092 - 112,250,130 (+)Ensembl
RefSeq Acc Id: XM_003826752   ⟹   XP_003826800
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24106,340,563 - 106,348,525 (+)NCBI
NHGRI_mPanPan15104,494,218 - 104,502,180 (+)NCBI
Mhudiblu_PPA_v05106,440,136 - 106,446,849 (+)NCBI
PanPan1.15112,242,490 - 112,249,200 (+)NCBI
Sequence:
RefSeq Acc Id: XM_055112532   ⟹   XP_054968507
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24106,340,561 - 106,347,284 (+)NCBI
NHGRI_mPanPan15104,494,216 - 104,500,939 (+)NCBI
Protein Sequences
Protein RefSeqs XP_003826800 (Get FASTA)   NCBI Sequence Viewer  
  XP_054968507 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000028937
  ENSPPAP00000028937.1
  ENSPPAP00000028939.1
Reference Protein Sequences
RefSeq Acc Id: XP_003826800   ⟸   XM_003826752
- Peptide Label: isoform X2
- UniProtKB: A0A2R9BKN6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000028939   ⟸   ENSPPAT00000051787
RefSeq Acc Id: ENSPPAP00000028937   ⟸   ENSPPAT00000051785
RefSeq Acc Id: XP_054968507   ⟸   XM_055112532
- Peptide Label: isoform X1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000037495 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000051785.1 UniProtKB/TrEMBL
  ENSPPAT00000051787.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1250.90 UniProtKB/TrEMBL
InterPro TSLP UniProtKB/TrEMBL
  TSLP_sf UniProtKB/TrEMBL
KEGG Report pps:100971967 UniProtKB/TrEMBL
NCBI Gene TSLP ENTREZGENE
PANTHER PTHR38003 UniProtKB/TrEMBL
  THYMIC STROMAL LYMPHOPOIETIN UniProtKB/TrEMBL
Pfam TSLP UniProtKB/TrEMBL
UniProt A0A2R9BH14_PANPA UniProtKB/TrEMBL
  A0A2R9BKN6 ENTREZGENE, UniProtKB/TrEMBL