CAPN10 (calpain 10) - Rat Genome Database

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Gene: CAPN10 (calpain 10) Pan paniscus
Analyze
Symbol: CAPN10
Name: calpain 10
RGD ID: 11719839
Description: ENCODES a protein that exhibits calcium-dependent cysteine-type endopeptidase activity (ortholog); cytoskeletal protein binding (ortholog); SNARE binding (ortholog); INVOLVED IN autophagy of mitochondrion (ortholog); mitochondrion organization (ortholog); positive regulation of apoptotic process (ortholog); ASSOCIATED WITH Bethlem Myopathy 1A (ortholog); chromosome 2q37 deletion syndrome (ortholog); D-2-hydroxyglutaric aciduria 1 (ortholog); FOUND IN cytoskeleton (ortholog); cytosol (ortholog); membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: calpain-10
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213143,264,218 - 143,280,660 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B143,279,184 - 143,295,625 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B127,838,477 - 127,851,334 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B246,645,632 - 246,658,490 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B246,645,630 - 246,679,169 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CAPN10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213143,264,218 - 143,280,660 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B143,279,184 - 143,295,625 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B127,838,477 - 127,851,334 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B246,645,632 - 246,658,490 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B246,645,630 - 246,679,169 (+)Ensemblpanpan1.1panPan2
CAPN10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382240,586,734 - 240,599,104 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2240,586,734 - 240,617,705 (+)EnsemblGRCh38hg38GRCh38
GRCh372241,526,151 - 241,538,521 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362241,174,818 - 241,205,795 (+)NCBINCBI36Build 36hg18NCBI36
Build 342241,246,141 - 241,277,112NCBI
Celera2235,198,477 - 235,210,856 (+)NCBICelera
Cytogenetic Map2q37.3NCBI
HuRef2233,282,748 - 233,295,178 (+)NCBIHuRef
CHM1_12241,532,185 - 241,544,581 (+)NCBICHM1_1
T2T-CHM13v2.02241,080,759 - 241,093,164 (+)NCBIT2T-CHM13v2.0
Capn10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39192,862,130 - 92,875,670 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl192,862,098 - 92,875,663 (+)EnsemblGRCm39 Ensembl
GRCm38192,934,408 - 92,947,948 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl192,934,376 - 92,947,941 (+)EnsemblGRCm38mm10GRCm38
MGSCv37194,830,985 - 94,844,525 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36194,764,814 - 94,778,354 (+)NCBIMGSCv36mm8
Celera195,879,004 - 95,892,543 (+)NCBICelera
Cytogenetic Map1DNCBI
Capn10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr89100,943,665 - 100,957,910 (+)NCBIGRCr8
mRatBN7.2993,498,132 - 93,510,494 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl993,498,478 - 93,510,494 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx9101,934,100 - 101,946,097 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09107,069,891 - 107,081,888 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.09105,426,045 - 105,438,042 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.09100,104,000 - 100,112,833 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl9100,104,000 - 100,112,832 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0999,767,655 - 99,776,488 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera991,034,781 - 91,046,660 (+)NCBICelera
Cytogenetic Map9q36NCBI
Capn10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955542874,083 - 885,084 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955542874,083 - 885,085 (-)NCBIChiLan1.0ChiLan1.0
CAPN10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12550,555,402 - 50,566,132 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2550,555,425 - 50,566,135 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2551,024,232 - 51,034,956 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02551,006,207 - 51,016,927 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2551,006,221 - 51,212,445 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12550,848,152 - 50,858,875 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02550,593,900 - 50,604,615 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02550,870,741 - 50,881,464 (+)NCBIUU_Cfam_GSD_1.0
Capn10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303192,177,907 - 192,189,909 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049367451,029,514 - 1,039,524 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CAPN10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15139,557,469 - 139,568,767 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115139,557,643 - 139,568,764 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
CAPN10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110126,613,722 - 126,626,388 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604072,768,979 - 72,782,938 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Capn10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248474,911,737 - 4,922,192 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248474,911,052 - 4,922,549 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000038620   ⟹   ENSPPAP00000015927
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B246,645,630 - 246,658,490 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000038632   ⟹   ENSPPAP00000015939
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B246,646,146 - 246,679,169 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000038637   ⟹   ENSPPAP00000015944
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B246,646,146 - 246,658,061 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000038638   ⟹   ENSPPAP00000015945
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B246,646,146 - 246,658,061 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000038644   ⟹   ENSPPAP00000015951
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B246,646,146 - 246,658,050 (+)Ensembl
RefSeq Acc Id: XM_055109296   ⟹   XP_054965271
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v213143,264,218 - 143,280,660 (+)NCBI
NHGRI_mPanPan12B143,279,186 - 143,295,625 (+)NCBI
RefSeq Acc Id: XM_055109297   ⟹   XP_054965272
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v213143,264,218 - 143,280,660 (+)NCBI
NHGRI_mPanPan12B143,279,187 - 143,295,625 (+)NCBI
RefSeq Acc Id: XM_063595627   ⟹   XP_063451697
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v213143,264,218 - 143,280,660 (+)NCBI
RefSeq Acc Id: XM_063595628   ⟹   XP_063451698
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v213143,264,218 - 143,280,660 (+)NCBI
RefSeq Acc Id: XM_063595629   ⟹   XP_063451699
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v213143,264,218 - 143,280,660 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: ENSPPAP00000015944   ⟸   ENSPPAT00000038637
RefSeq Acc Id: ENSPPAP00000015945   ⟸   ENSPPAT00000038638
RefSeq Acc Id: ENSPPAP00000015939   ⟸   ENSPPAT00000038632
RefSeq Acc Id: ENSPPAP00000015927   ⟸   ENSPPAT00000038620
RefSeq Acc Id: ENSPPAP00000015951   ⟸   ENSPPAT00000038644
RefSeq Acc Id: XP_054965271   ⟸   XM_055109296
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054965272   ⟸   XM_055109297
- Peptide Label: isoform X4
- UniProtKB: A0A2R9AF24 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063451697   ⟸   XM_063595627
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063451698   ⟸   XM_063595628
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063451699   ⟸   XM_063595629
- Peptide Label: isoform X5
- UniProtKB: A0A2R9ALU0 (UniProtKB/TrEMBL)
Protein Domains
Calpain catalytic   Peptidase C2 calpain


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000031063 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000038620.1 UniProtKB/TrEMBL
  ENSPPAT00000038632.1 UniProtKB/TrEMBL
  ENSPPAT00000038637.1 UniProtKB/TrEMBL
  ENSPPAT00000038638.1 UniProtKB/TrEMBL
  ENSPPAT00000038644.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.380 UniProtKB/TrEMBL
  Cysteine proteinases UniProtKB/TrEMBL
InterPro C2_III UniProtKB/TrEMBL
  Calpain_cysteine_protease UniProtKB/TrEMBL
  Calpain_domain_III UniProtKB/TrEMBL
  Calpain_III UniProtKB/TrEMBL
  Calpain_III_sf UniProtKB/TrEMBL
  Papain-like_cys_pep_sf UniProtKB/TrEMBL
  Pept_cys_AS UniProtKB/TrEMBL
  Peptidase_C2_calpain_cat UniProtKB/TrEMBL
NCBI Gene CAPN10 ENTREZGENE
PANTHER CALPAIN UniProtKB/TrEMBL
  PTHR10183:SF30 UniProtKB/TrEMBL
Pfam Calpain_III UniProtKB/TrEMBL
  Peptidase_C2 UniProtKB/TrEMBL
PRINTS CALPAIN UniProtKB/TrEMBL
PROSITE CALPAIN_CAT UniProtKB/TrEMBL
  THIOL_PROTEASE_CYS UniProtKB/TrEMBL
SMART calpain_III UniProtKB/TrEMBL
  CysPc UniProtKB/TrEMBL
Superfamily-SCOP SSF49758 UniProtKB/TrEMBL
  SSF54001 UniProtKB/TrEMBL
UniProt A0A2R9AF24 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9AF55_PANPA UniProtKB/TrEMBL
  A0A2R9AJZ5_PANPA UniProtKB/TrEMBL
  A0A2R9ALT4_PANPA UniProtKB/TrEMBL
  A0A2R9ALU0 ENTREZGENE, UniProtKB/TrEMBL