DRD5 (dopamine receptor D5) - Rat Genome Database

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Gene: DRD5 (dopamine receptor D5) Pan paniscus
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Symbol: DRD5
Name: dopamine receptor D5
RGD ID: 11669679
Description: ENCODES a protein that exhibits dopamine neurotransmitter receptor activity (ortholog); G-protein alpha-subunit binding (ortholog); INVOLVED IN adenylate cyclase-activating dopamine receptor signaling pathway (ortholog); adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); associative learning (ortholog); PARTICIPATES IN dopamine signaling pathway; dopamine signaling pathway via D1 family of receptors; G protein mediated signaling pathway via Galphaq family; ASSOCIATED WITH Alzheimer's disease (ortholog); attention deficit hyperactivity disorder (ortholog); Benign Essential Blepharospasm (ortholog); FOUND IN axon (ortholog); brush border membrane (ortholog); dendrite (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: D(1B) dopamine receptor
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2310,026,932 - 10,030,293 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1410,235,569 - 10,237,977 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v044,189,536 - 4,193,144 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.149,508,711 - 9,511,072 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl49,509,094 - 9,510,527 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
DRD5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2310,026,932 - 10,030,293 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1410,235,569 - 10,237,977 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v044,189,536 - 4,193,144 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.149,508,711 - 9,511,072 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl49,509,094 - 9,510,527 (+)Ensemblpanpan1.1panPan2
DRD5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3849,781,634 - 9,784,009 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl49,781,634 - 9,784,009 (+)EnsemblGRCh38hg38GRCh38
GRCh3749,783,258 - 9,785,633 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3649,392,701 - 9,394,731 (+)NCBINCBI36Build 36hg18NCBI36
Build 3449,459,871 - 9,461,901NCBI
Celera410,266,117 - 10,268,492 (+)NCBICelera
Cytogenetic Map4p16.1NCBI
HuRef49,117,663 - 9,120,038 (+)NCBIHuRef
CHM1_149,781,174 - 9,783,549 (+)NCBICHM1_1
T2T-CHM13v2.049,781,407 - 9,783,782 (+)NCBIT2T-CHM13v2.0
Drd5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39538,476,742 - 38,479,868 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl538,476,710 - 38,479,861 (+)EnsemblGRCm39 Ensembl
GRCm38538,319,509 - 38,322,523 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl538,319,367 - 38,322,518 (+)EnsemblGRCm38mm10GRCm38
MGSCv37538,710,748 - 38,713,549 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36538,607,758 - 38,610,559 (+)NCBIMGSCv36mm8
Celera535,773,146 - 35,775,947 (+)NCBICelera
Cytogenetic Map5B3NCBI
cM Map520.4NCBI
Drd5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81476,700,244 - 76,703,344 (-)NCBIGRCr8
mRatBN7.21472,487,950 - 72,491,050 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1472,489,347 - 72,490,774 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1476,931,000 - 76,932,427 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01478,171,890 - 78,173,317 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01474,611,945 - 74,613,372 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01477,220,579 - 77,222,006 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1477,220,579 - 77,222,006 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01477,202,167 - 77,203,594 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41477,768,060 - 77,769,487 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11477,770,450 - 77,771,878 (-)NCBI
Celera1471,440,495 - 71,441,922 (-)NCBICelera
Cytogenetic Map14q21NCBI
Drd5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555145,450,495 - 5,452,282 (+)NCBIChiLan1.0ChiLan1.0
DRD5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1369,621,187 - 69,623,522 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl369,621,734 - 69,623,893 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha372,173,244 - 72,175,212 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0370,378,089 - 70,380,057 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl370,378,633 - 70,380,057 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1369,652,224 - 69,654,192 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0369,817,637 - 69,819,605 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0370,198,942 - 70,200,910 (-)NCBIUU_Cfam_GSD_1.0
Drd5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528563,158,693 - 63,162,200 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647716,861,773 - 16,863,215 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647716,860,222 - 16,863,505 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DRD5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl86,180,221 - 6,181,636 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.186,180,221 - 6,182,575 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.285,694,230 - 5,696,186 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DRD5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12740,267,681 - 40,270,061 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2740,268,235 - 40,269,671 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604787,064,155 - 87,066,433 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Drd5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475521,358,586 - 21,361,410 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003826782 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSPPAT00000026181   ⟹   ENSPPAP00000005874
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl49,509,094 - 9,510,527 (+)Ensembl
RefSeq Acc Id: XM_003826782   ⟹   XP_003826830
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2310,026,932 - 10,030,293 (+)NCBI
NHGRI_mPanPan1410,235,569 - 10,237,977 (+)NCBI
Mhudiblu_PPA_v044,189,536 - 4,193,144 (+)NCBI
PanPan1.149,508,711 - 9,511,072 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003826830 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000005874.1
RefSeq Acc Id: XP_003826830   ⟸   XM_003826782
- UniProtKB: A0A2R8ZLP4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000005874   ⟸   ENSPPAT00000026181

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000023786 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000026181.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro Dopamine_D5_rcpt UniProtKB/TrEMBL
  Dopamine_rcpt UniProtKB/TrEMBL
  GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
KEGG Report pps:100994450 UniProtKB/TrEMBL
NCBI Gene DRD5 ENTREZGENE
PANTHER ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR UniProtKB/TrEMBL
  D(1B) DOPAMINE RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/TrEMBL
PRINTS DOPAMINED1BR UniProtKB/TrEMBL
  DOPAMINER UniProtKB/TrEMBL
  GPCRRHODOPSN UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
SMART 7TM_GPCR_Srsx UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A2R8ZLP4 ENTREZGENE, UniProtKB/TrEMBL