ELP1 (elongator acetyltransferase complex subunit 1) - Rat Genome Database

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Gene: ELP1 (elongator acetyltransferase complex subunit 1) Pan paniscus
Analyze
Symbol: ELP1
Name: elongator acetyltransferase complex subunit 1
RGD ID: 11668347
Description: ENCODES a protein that exhibits ATP binding (ortholog); protein kinase activity (ortholog); INVOLVED IN I-kappaB phosphorylation (ortholog); ASSOCIATED WITH asthma (ortholog); Breast Neoplasms (ortholog); Charcot-Marie-Tooth disease (ortholog); FOUND IN elongator holoenzyme complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: elongator complex protein 1; IKBKAP
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21130,475,862 - 30,540,680 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1930,478,226 - 30,543,043 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0980,020,131 - 80,085,076 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19108,194,008 - 108,258,500 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9108,194,011 - 108,258,500 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ELP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21130,475,862 - 30,540,680 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1930,478,226 - 30,543,043 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0980,020,131 - 80,085,076 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19108,194,008 - 108,258,500 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9108,194,011 - 108,258,500 (-)Ensemblpanpan1.1panPan2
ELP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389108,867,517 - 108,934,124 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9108,866,898 - 108,934,328 (-)EnsemblGRCh38hg38GRCh38
GRCh379111,629,797 - 111,696,404 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369110,669,621 - 110,736,217 (-)NCBINCBI36Build 36hg18NCBI36
Build 349108,709,355 - 108,775,951NCBI
Celera982,129,095 - 82,195,809 (-)NCBICelera
Cytogenetic Map9q31.3NCBI
HuRef981,229,552 - 81,296,258 (-)NCBIHuRef
CHM1_19111,776,416 - 111,843,122 (-)NCBICHM1_1
T2T-CHM13v2.09121,036,644 - 121,103,197 (-)NCBIT2T-CHM13v2.0
Elp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39456,746,547 - 56,802,565 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl456,749,680 - 56,802,331 (-)EnsemblGRCm39 Ensembl
GRCm38456,746,547 - 56,802,569 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl456,749,680 - 56,802,331 (-)EnsemblGRCm38mm10GRCm38
MGSCv37456,762,552 - 56,815,203 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36456,844,828 - 56,896,313 (-)NCBIMGSCv36mm8
Celera456,657,583 - 56,710,224 (-)NCBICelera
Cytogenetic Map4B3NCBI
cM Map431.66NCBI
Elp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8576,248,545 - 76,300,985 (-)NCBIGRCr8
mRatBN7.2571,453,338 - 71,505,833 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl571,456,310 - 71,505,762 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx573,340,793 - 73,393,272 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0575,172,255 - 75,224,700 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0575,144,331 - 75,196,776 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0573,503,406 - 73,552,798 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl573,503,407 - 73,552,798 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0577,661,315 - 77,710,707 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4574,657,287 - 74,707,435 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1574,662,400 - 74,712,548 (-)NCBI
Celera570,310,353 - 70,359,709 (-)NCBICelera
Cytogenetic Map5q24NCBI
Elp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541918,038,507 - 18,095,894 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541918,035,197 - 18,097,681 (+)NCBIChiLan1.0ChiLan1.0
ELP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11164,035,667 - 64,094,402 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1164,037,506 - 64,093,819 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1162,437,897 - 62,496,433 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01165,169,787 - 65,228,593 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1165,170,724 - 65,228,543 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11163,690,982 - 63,749,074 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01163,709,775 - 63,768,691 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01164,402,753 - 64,461,318 (-)NCBIUU_Cfam_GSD_1.0
Elp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947179,284,678 - 179,342,148 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365593,924,185 - 3,983,028 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365593,924,185 - 3,981,907 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ELP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1249,905,351 - 249,981,641 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11249,905,550 - 249,980,570 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21280,435,992 - 280,511,016 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ELP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11230,620,685 - 30,687,583 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1230,620,278 - 30,687,405 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603511,996,706 - 12,063,562 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Elp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247582,575,671 - 2,646,313 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247582,575,516 - 2,646,313 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000031171   ⟹   ENSPPAP00000008535
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl9108,194,011 - 108,258,500 (-)Ensembl
RefSeq Acc Id: XM_003810890   ⟹   XP_003810938
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21130,475,862 - 30,540,680 (+)NCBI
NHGRI_mPanPan1930,478,226 - 30,543,043 (+)NCBI
Mhudiblu_PPA_v0980,020,131 - 80,085,076 (-)NCBI
PanPan1.19108,194,008 - 108,258,500 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034967934   ⟹   XP_034823825
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21130,475,871 - 30,540,680 (+)NCBI
NHGRI_mPanPan1930,478,235 - 30,543,043 (+)NCBI
Mhudiblu_PPA_v0980,021,255 - 80,085,034 (-)NCBI
Protein Sequences
Protein RefSeqs XP_003810938 (Get FASTA)   NCBI Sequence Viewer  
  XP_034823825 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000008535.1
Reference Protein Sequences
RefSeq Acc Id: XP_003810938   ⟸   XM_003810890
- Peptide Label: isoform X1
- UniProtKB: A0A2R8ZU92 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034823825   ⟸   XM_034967934
- Peptide Label: isoform X2
- UniProtKB: A0A2R8ZU92 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000008535   ⟸   ENSPPAT00000031171


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000027510 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000031171.1 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
InterPro Elp1 UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
KEGG Report pps:100986506 UniProtKB/TrEMBL
NCBI Gene IKBKAP ENTREZGENE
PANTHER ELONGATOR COMPLEX PROTEIN 1 UniProtKB/TrEMBL
  PTHR12747 UniProtKB/TrEMBL
Pfam IKI3 UniProtKB/TrEMBL
PIRSF IKAP UniProtKB/TrEMBL
Superfamily-SCOP Tricorn protease domain 2 UniProtKB/TrEMBL
UniProt A0A2R8ZU92 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-09-29 ELP1  elongator acetyltransferase complex subunit 1  ELP1  elongator complex protein 1  Symbol and/or name change 5135510 APPROVED
2017-05-09 ELP1  elongator complex protein 1  IKBKAP  inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein  Symbol and/or name change 5135510 APPROVED