GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | PRDX2 | affects expression | EXP | | 6480464 | CTD | Doxorubicin affects the expression of PRDX2 mRNA | PMID:29803840 | PRDX2 | decreases response to substance | EXP | | 6480464 | CTD | PRDX2 protein results in decreased susceptibility to Doxorubicin | PMID:23911960 | PRDX2 | increases expression | ISO | Prdx2 (Mus musculus) | 6480464 | CTD | Doxorubicin results in increased expression of PRDX2 mRNA; Doxorubicin results in increased expression of PRDX2 protein | PMID:21463615 | PRDX2 | increases oxidation | ISO | Prdx2 (Rattus norvegicus) | 6480464 | CTD | Doxorubicin results in increased oxidation of PRDX2 protein | PMID:28818578 | PRDX2 | multiple interactions | ISO | Prdx2 (Mus musculus) | 6480464 | CTD | MT1 affects the reaction [Doxorubicin results in increased expression of PRDX2 mRNA]; MT1 affects the reaction [Doxorubicin results in increased expression of PRDX2 protein]; MT2 affects the reaction [Doxorubicin results in increased expression of PRDX2 mRNA]; MT2 affects the reaction [Doxorubicin results in increased expression of PRDX2 protein] | PMID:21463615 | | ||||||||||||||||||||||
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