GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Stat3 | increases expression | ISO | STAT3 (Homo sapiens) | 6480464 | CTD | Nickel results in increased expression of STAT3 mRNA | PMID:24768652 PMID:25583101 | Stat3 | multiple interactions | ISO | STAT3 (Homo sapiens) | 6480464 | CTD | 2-((aminocarbonyl)amino)-5-(4-fluorophenyl)-3-thiophenecarboxamide inhibits the reaction [[Nickel co-treated with lipopolysaccharide, E. coli O26-B6] results in increased phosphorylation of STAT3 protein]; [Nickel co-treated with lipopolysaccharide, E. coli O26-B6] results in increased phosphorylation of STAT3 protein; N'-(7-fluoroH-pyrrolo(1,2-a)quinoxalin-4-yl)pyrazine-2-carbohydrazide promotes the reaction [[Nickel co-treated with lipopolysaccharide, E. coli O26-B6] results in increased phosphorylation of STAT3 protein] | PMID:35623502 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |