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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3870
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tlr4
Name: toll-like receptor 4
Acc ID: CHEBI:15600
Term: (+)-catechin
Definition: The (+)-enantiomer of catechin and a polyphenolic antioxidant plant metabolite.
Chemical ID: MESH:D002392
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tlr4multiple interactionsISOTLR4 (Homo sapiens)6480464CTD[epigallocatechin gallate co-treated with gallocatechol co-treated with epicatechin gallate co-treated with Catechin analog] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TLR4 protein]PMID:26187476
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