GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | HMOX1 | decreases activity | ISO | Hmox1 (Rattus norvegicus) | 6480464 | CTD | protoporphyrin IX results in decreased activity of HMOX1 protein | PMID:19234301 | HMOX1 | multiple interactions | ISO | Hmox1 (Rattus norvegicus) | 6480464 | CTD | protoporphyrin IX inhibits the reaction [[Sulfasalazine results in increased expression of HMOX1 protein] which results in increased expression of CDKN1A protein]; protoporphyrin IX inhibits the reaction [Hemin results in increased activity of HMOX1 protein] | PMID:18845130 PMID:19234301 | |
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